Clinical trials: sponsored by Rennes University Hospital
Myocardial Iron Overload, HFE-Associated Hereditary Hemochromatosis
Estimation of Myocardial Iron Overload by 3 Tesla MRI in HFE Hereditary Haemochromatosis
Hereditary haemochromatosis (HHC) is a frequent disease in Brittany (5 to 7‰), responsible first for biological disorder in blood iron parameters and minor clinical disorders, before evolving to potential life-threatening…
- Trial name
- HEMOCOEUR (NCT02099214)
- Testing
- 3Tesla cardiac MRI, Electrocardiogram (EKG), Iron and cardiac markers
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Biliary Concentration of Tacrolimus
Therapeutic Drug Monitoring of Tacrolimus Biliary Concentrations for Liver-transplanted Patients (STABILE)
The purpose of this study is to demonstrate that the biliary concentration of TCR is a good marker of its immunosuppressive activity.
- Trial name
- STABILE (NCT02820259)
- Testing
- Tacrolimus
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Rennes University Hospital
Renal Colic
Use of Analgesic Drugs in Renal Colic in Emergency Room
A prospective non-interventional study on the use of analgesic drugs in renal colic in emergency rooms
- Trial name
- NEPHROPAIN (NCT03278652)
- Testing
- Consumption of drugs for analgesic use
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Rennes University Hospital
Infertility
Improved Medically Assisted Procreation Monitoring
Patient care in Medically Assisted Procreation (MAP) requires a close and regular monitoring of the evolution of the estradiol rate.
- Trial name
- NGAMP (NCT03274765)
- Testing
- Dosage of oestradiol
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Rennes University Hospital
Trauma, Emergencies
Descriptive Study of Trampoline Accidents in the Pediatric Emergency Department of Rennes
The aim of this study is to compare trauma related to others sport to trauma due to trampoline in pediatric emergencies of Rennes.
- Conditions
- Trauma, Emergencies, Child, Only
- Trial name
- TRAUMPO (NCT03250936)
- Where
- France
- Volunteers
- 4,000 people
- Sponsor
- Rennes University Hospital
Urinary Tract Infections in Children
Evaluation of Pain in Urinary Collections in Pediatric Emergencies in Children Who Have Not Acquired Cleanliness
Observational study.
- Trial name
- SONDAPU (NCT03263845)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Rennes University Hospital
Rheumatoid Arthritis
Validation of the French Version of the Health Assessment Questionnaire II (HAQ-II) for Rheumatoid Arthritis
The purpose of the study is to develop a validated French version of the HAQ-II questionnaire for rheumatoid arthritis.
- Trial name
- HAQ-II (NCT03249467)
- Where
- France
- Volunteers
- 129 people
- Sponsor
- Rennes University Hospital
Hypertriglyceridemia, Cutaneous T Cell Lymphoma
Carbohydrate Metabolism Disorder Frequency in Hypertriglyceridemia Induced by Bexarotene of Cutaneous T Cell Lymphoma
Bexarotene is a RXR-selective retinoid, licensed for the treatment of cutaneous T cell lymphoma. The most frequent adverse effect is hypertriglyceridemia but its mechanism is not well known.
- Trial name
- TgBEX (NCT01569724)
- Testing
- oral glucose tolerance test (OGTT)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Rennes University Hospital
Ulcerative Colitis
Interest of Propionibacterium Freudenreichii for the Treatment of Mild to Moderate Ulcerative Colitis
Ulcerative colitis (UC) is an immune mediated chronic inflammatory bowel disease that results at least in part of an abnormal immune response to environmental factors including the intestinal microbiota.
- Trial name
- EMMENTAL (NCT02488954)
- Testing
- Probiotics in the form of cheese portion
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Rennes University Hospital
Hemiplegic Patients
Interest of Evaluating the Movement of the Center of Mass in a Dynamic Avoidance Task as the Endpoint of the Dynamic Equilibrium of Hemiplegic Patients
For several years, the postural disorders assessment in hemiplegic patients was conducted through force plate, using the center of plantar pressure displacement in a static position.
- Trial name
- EQHEM (NCT02350556)
- Testing
- Dynamic Avoidance Task, physical therapy, 3D motion on optoelectronic device
- Where
- France
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Joint Effusion
Use of Infrared Spectroscopy in Septic Arthritis Diagnosis
The main objective of this study is to assess the ability of Fiber-optic Evanescent Wave Spectroscopy (FEWS) to discriminate synovial fluids samples of septic arthritis patients from other causes of joint effusion by analyzing ex…
- Trial name
- SynoFAST (NCT02860871)
- Testing
- infrared spectroscopy
- Where
- France
- Volunteers
- 611 people
- Sponsor
- Rennes University Hospital
Ulcerative Colitis, Crohn's Disease
Validation of the French Version of the Inflammatory Bowel Disease Questionnaire (IBDQ) for Ulcerative Colitis and Crohn's Disease
The purpose of the study is to develop a validated French version of the IBDQ in a cohort of patients suffering from Inflammatory bowel diseases, namely Crohn's disease and Ulcerative Colitis.
- Trial name
- F-IBDQ (NCT01891214)
- Testing
- Validation of the French Version of the Inflammatory Bowel Disease Questionnaire (IBDQ)
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Rennes University Hospital
IVF, Endometriosis
VARITI-5 : Study of Variations of Serum ITIH5 in Women During the Genital Life and in Pathological Situations
The five proteins of the ITI (Inter-α-trypsin inhibitor) family, are essential components of the extracellular matrix, the dynamics of which they participate in the processes of cellular differentiation and proliferation. I.
- Trial name
- VARITI-5 (NCT01826500)
- Testing
- blood test
- Where
- 2 sites in France
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Stage IIIb and IV Non Small Cell Lung Cancer
Molecular Diagnosis on Circulating Tumor DNA of Non-Small Cell Lung Cancer
The purpose of this study is to develop an ultra sensitive assay of mutation detection on circulating tumor DNA (ctDNA) for treatment, diagnosis and monitoring disease progression of Non-Small Cell Lung Cancer (NSCLC).
- Trial name
- ANTiCIPe (NCT02169349)
- Testing
- laboratory biomarker analysis, Next Generation Sequencing, DNA Analysis
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Rennes University Hospital
Bladder Cancer
FIRBladd - Use of Infrared Spectroscopy in the Diagnosis of Bladder Tumors
The purpose of this study is too assess infrared spectroscopy ability to discriminate urine of a patient affected by bladder cancer from urine of reference patient.
- Trial name
- FIRBladd (NCT02149862)
- Testing
- Urine infrared analysis
- Where
- France
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Knee Prosthesis
Positioning of the Tibial Cut in Unicompartmental Medial Knee Replacement by Using Patient Specific Cutting Guides.
Unicompartmental knee replacements are performed to treat osteoarthritis or osteonecrosis of the knee especially when it affects only the medial femoro-tibial compartment. To place the prosthesis, bone removal is necessary.
- Trial name
- PSI-PUC (NCT02018484)
- Testing
- Unicompartmental Knee Replacement
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Rennes University Hospital
Fatty Liver, Non-alcoholic Fatty Liver Disease
Using Infrared Spectroscopy for Diagnosis Severity of Nonalcoholic Fatty Liver Disease
The main objective of this study is to evaluate the ability of infrared spectroscopy to discriminate simple hepatic steatosis from NASH
- Trial name
- NASH (NCT02860884)
- Testing
- liver biopsy, infrared spectroscopy
- Where
- France
- Volunteers
- 136 people
- Sponsor
- Rennes University Hospital
Died, in End-of-life Situation
Better Understand End-of-life Emergencies' Management Among Elderly in Nursing Homes: a Pilot Study in Brittany, France
The purposes of this study are : To know and to understand frequency and variability (quantitative and qualitative) of end-of-life emergencies in nursing homes.
- Trial name
- PUFPAE (NCT02852733)
- Testing
- end-of-life emergencies' management
- Where
- France
- Volunteers
- 602 people
- Sponsor
- Rennes University Hospital
Neuropathic Pain Evaluation
Neuropathic Evaluation of Postoperative Pain
Chronic postsurgical pain (CPSP) is defined by pain persisting longer than 2 months after surgery (1). Its incidence varies from 10 to 50 % in the literature (2). A high proportion of CPSP is neuropathic (CPSNP) (4).
- Trial name
- DN4-SFAR (NCT02826317)
- Testing
- preoperative and postoperative setting
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Rennes University Hospital
Peripheral Arterial Disease
Optimized Supervised Education Program for Peripheral Arterial Disease
Peripheral arterial disease (PAD) is a frequent and serious chronic disease witch is undertreated. The recommended management of PAD include pharmacological approach and lifestyle modifications.
- Trial name
- POPART (NCT01065740)
- Testing
- Patient education
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Rennes University Hospital