Clinical trials: sponsored by Research Inc
Depression, Functional Impairment
The Health and Social Consequences of Depression Among the Elderly
Mental illnesses often go undiagnosed or untreated in low-income settings. Mental health care may be especially important for the elderly - events in the lives of the elderly, like illnesses or deaths of peers, may put these…
- Trial name
- NCT05856552
- Testing
- CBT, Group Activities
- Where
- 2 sites in India
- Volunteers
- 5,370 people, healthy volunteers welcome
- Sponsor
- National Bureau of Economic Research, Inc.
Pain Management
Neurofeedback-EEG-VR System for Non-opioid Pain Therapy
This study will assess the feasibility of developing the Neurofeedback-EEG-VR (NEVR) system for non-opioid pain therapy. Subjects suffering from pain will undergo sessions involving VR and Neurofeedback training and their pain…
- Trial name
- NEVR (NCT04551092)
- Testing
- NEVR
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Quantum Applied Science & Research, Inc.
Depression, Anxiety, Fear
Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression
This mechanistic study uses an anti anxiety drug and brain imaging to study the threat processing system and associated brain circuits in people with depression, anxiety disorders and comorbid depression and anxiety disorders.
- Conditions
- Depression, Anxiety, Fear, Depression, Anxiety and Fear
- Trial name
- NCT06004115
- Testing
- Lorazepam
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Healthy Controls
Dose-Dependent Effects of Low-Intensity Focused Ultrasound
Low-intensity focused ultrasound (LIFU) has emerged as a tool to modulate the activity of deep brain structures noninvasively and reversibly, with anatomical precision.
- Trial name
- NCT07099950
- Testing
- Low-intensity focused ultrasound
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Anorexia Nervosa, Body Image Disturbance
Interoceptive Mechanisms of Body Image Disturbance in Anorexia Nervosa
The proposed study utilizes a randomized experimental therapeutics design to test a mechanistic framework linking interoceptive processing and disturbed body image, with the purpose of informing the development of future…
- Conditions
- Anorexia Nervosa, Body Image Disturbance, Interoception
- Trial name
- NCT06332963
- Testing
- Floatation-REST, IFT, EFT
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Plaque Psoriasis
Study to Assess the Reliability of PASI Scoring Using Digital-Based Images
This is an open-labeled study to evaluate the reliability of digital photographs for the remote assessment of the disease severity of plaque psoriasis.
- Trial name
- NCT05835843
- Testing
- In-Person and Remote Disease Assessment
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Innovaderm Research Inc.
Ischemic Stroke
A Study of NCS-01 in Patients With Acute Ischemic Stroke
This is an initial Phase1/2 dose-finding, randomized, multi-center study to evaluate the safety and tolerability of NCS-01 in patients with acute ischemic stroke. All patients will be randomized within 48 hours of stroke onset.
- Trial name
- NCT03915431
- Testing
- NCS-01
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- NC Medial Research Inc
Loneliness
The Economic Consequences of Loneliness Among the Elderly
Elderly individuals across the world are increasingly living alone. However, little is known about the effects of loneliness on economic and health outcomes.
- Trial name
- NCT04225845
- Testing
- Phone therapy, Cash transfer
- Where
- India
- Volunteers
- 1,120 people, healthy volunteers welcome
- Sponsor
- National Bureau of Economic Research, Inc.
Aging
The Causal Effects of Old Age Pensions
Old age pensions are a common feature of welfare policy worldwide. However, little is known about the effect of these pensions on the recipients and their families.
- Trial name
- NCT04029194
- Testing
- Assistance with old age pension application
- Where
- India
- Volunteers
- 1,459 people
- Sponsor
- National Bureau of Economic Research, Inc.
Major Depressive Disorder
Lipopolysaccharide (LPS) Challenge in Depression
LPS Challenge in Individuals with Major Depressive Disorder
- Trial name
- NCT03142919
- Testing
- Lipopolysaccharide
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Safety Issues, Tolerance
Phase1 First in Human Ascending Dose Study to Evaluate the Safety and Tolerability of FC-12738 in Health Adults
A Phase I, Randomized, Double-Blind, Placebo-Controlled, First-in-human, Single-Ascending-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of retro enversio (RT) thymopentin in Healthy Adult…
- Trial name
- NCT05978908
- Testing
- FC-12738, Saline
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Neurodegenerative Disease Research Inc
Bipolar Depression
Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression
This is a 2x2, within-subjects, cross-over trial to test the anti-depressant effects of acute exercise in 20 participants with bipolar depression.
- Trial name
- NCT06088732
- Testing
- Exercise Session, Ibuprofen 800 mg, Rest
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Safety Issues, Tolerability
Single Ascending Dose and Multiple Ascending Dose Study of AVR-48
This is a Phase 1 (healthy adult volunteers), 2-part, double-blind, randomized, placebo controlled trial to evaluate the safety and pharmacokinetic (PK) profiles of escalating single doses of AVR-48 versus placebo (SAD) and…
- Conditions
- Safety Issues, Tolerability, Pharmacokinetics, Pharmacodynamics
- Trial name
- NCT06847698
- Testing
- AVR-48
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AyuVis Research, Inc.
Atopic Dermatitis
Effects of Abrocitinib in Subjects With Atopic Dermatitis With an Unsatisfactory Response After Treatment With Dupilumab
This is a single-arm, open-label study that will examine the effect of abrocitinib in subjects with atopic dermatitis.
- Trial name
- NCT05602207
- Testing
- Abrocitinib
- Where
- 12 sites in United States, Canada
- Volunteers
- 24 people
- Sponsor
- Innovaderm Research Inc.
Atopic Dermatitis
Short-Term Efficacy of Triamcinolone Acetonide (Aristocort® C) in Subjects with Atopic Dermatitis
This study is a randomized, intraindividual study to evaluate the short-term efficacy of triamcinolone acetonide (Aristocort® C) in subjects with atopic dermatitis.
- Trial name
- NCT05844618
- Testing
- Triamcinolone Acetonide (Aristocort® C), Vehicle
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Innovaderm Research Inc.
Discoid Lupus Erythematosus
Study to Evaluate the Efficacy of Ruxolitinib 1.5% Cream in Adult Subjects with Discoid Lupus Erythematosus
This study is a single-blind, intraindividual study to evaluate the efficacy of ruxolitinib 1.5 % cream in adult subjects with discoid lupus erythematosus.
- Trial name
- NCT06261021
- Testing
- Ruxolitinib 1.5% cream, Application without occlusion in Area 1, Application under occlusion at night in Area 2
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- Innovaderm Research Inc.
Schizophrenia, Bipolar Disorder
Contingency Management for Problematic Behavior Reduction in the Community
This study aims to determine the feasibility and effectiveness of implementing a contingency management program in a small group of mentally ill, unhoused individuals with schizophrenia or bipolar disorder and anosognosia (a lack…
- Conditions
- Schizophrenia, Bipolar Disorder, Anosognosia
- Trial name
- NCT06486584
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Influenza, Vaccination
Using Explainable AI Risk Predictions to Nudge Influenza Vaccine Uptake
The study team previously demonstrated that patients are more likely to receive flu vaccine after learning that they are at high risk for flu complications.
- Conditions
- Influenza, Vaccination, Health Promotion, Health Behavior
- Trial name
- NCT05009251
- Testing
- Reminder, Risk reduction, Medical records-based recommendation
- Where
- United States
- Volunteers
- 45,061 people
- Sponsor
- National Bureau of Economic Research, Inc.
Influenza, Vaccination
Lottery Incentive Nudges to Increase Influenza Vaccinations
In the current study, the study team will explore whether small incentives are effective at promoting flu vaccine uptake. The study is designed to compare the relative efficacy of incentives of equal perceived expected value (EV)…
- Conditions
- Influenza, Vaccination, Health Promotion, Health Behavior
- Trial name
- NCT05012163
- Testing
- Reminder, Financial incentive, Lottery
- Where
- United States
- Volunteers
- 57,581 people
- Sponsor
- National Bureau of Economic Research, Inc.
Hidradenitis Suppurativa (HS)
Participants with Mild to Moderate Hidradenitis Suppurativa Will Receive EVO101 a Topical Cream 0.1%
The goal of this clinical trial is to learn if drug EVO101 works to treat mild to moderate hidradenitis suppurativa in adults. The main questions it aims to answer are: Does drug EVO101 lower the total number of lesion a…
- Trial name
- NCT06645821
- Testing
- EVO101
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Virginia Clinical Research, Inc.