Clinical trials: sponsored by Research Inc
Family Relations
Testing Relationship Skills Education Services With a Robust Economic Security Component
The Parenting Center (TPC) offers the Empowering Families program, which integrates a relationship education curriculum (Family Wellness) into a comprehensive set of services that includes case management, employment services…
- Trial name
- TPC (NCT02902003)
- Testing
- Empowering Families
- Where
- United States
- Volunteers
- 1,758 people, healthy volunteers welcome
- Sponsor
- Mathematica Policy Research, Inc.
Attitudes, Knowledge
Testing the Effectiveness of the Full and Abridged Relationship Smarts Curriculum for 9th Grade Students
This evaluation will test the program effectiveness of a relationship education program (Relationship Smarts PLUS)and an abridged version of the program to 9th Grade Students on outcomes of knowledge.
- Trial name
- NCT02832856
- Testing
- Healthy Relationship Education, Job Readiness Curriculum
- Where
- United States
- Volunteers
- 1,180 people, healthy volunteers welcome
- Sponsor
- Mathematica Policy Research, Inc.
Heart Failure
NATriuretic Response to Expansion and dIUretics in huMans With Heart Failure
NATRIUM-HF is a multicenter, non-randomized, pre-post intervention study designed to assess renal response to intravascular fluid expansion and diuretics after sacubitril/valsartan (Entresto®) in euvolemic heart failure patients…
- Trial name
- NATRIUM-HF (NCT04235062)
- Testing
- Ringer's (8.6 g/L sodium chloride, 0.33 g/L calcium chloride, 0.3 g/L potassium chloride) Solution, Intravenous Bolus Furosemide
- Where
- 13 sites in Armenia, Bosnia and Herzegovina and 1 more
- Volunteers
- 229 people
- Sponsor
- Momentum Research, Inc.
Anorexia Nervosa
Effects of Reduced Environmental Stimulation on Eating Disorders
The study proposed in this protocol aims to document the physiological, subjective, behavioral, and neural effects of reduced environmental stimulation (floating) in patients with current or prior anorexia nervosa The primary aim…
- Trial name
- NCT02801084
- Testing
- Reduced environmental stimulation
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Any Injury or Illness Acutely Impacting Work
Minnesota RETAIN Impact Evaluation
This study is a randomized control trial (RCT) to evaluate the impact of RETAIN program expansion and services on workforce retention and reduction of future workplace disability in the state of MN.
- Trial name
- NCT05146349
- Testing
- Minnesota RETAIN
- Where
- United States
- Volunteers
- 3,200 people
- Sponsor
- Mathematica Policy Research, Inc.
Covid19
The Doctors for Coronavirus Prevention Project Thanksgiving / Christmas Messaging Campaign
Facebook ads with physician-delivered videos were shown before the Thanksgiving and Christmas holidays and focused on staying safe during the COVID pandemic by limiting travel and mask-wearing.
- Trial name
- NCT04644328
- Testing
- Facebook Ads on the importance of staying safe during the Thanksgiving / Christmas holiday
- Where
- United States
- Volunteers
- 820 people, healthy volunteers welcome
- Sponsor
- National Bureau of Economic Research, Inc.
Early Intervention, Educational (Head Start and Early Head Start Access and Participation)
Head Start REACH: Strengthening Outreach, Recruitment and Engagement Approaches With Families
Mathematica, funded by the Administration for Children and Families (ACF) Office of Planning, Research, and Evaluation (OPRE) in the U.S.
- Trial name
- HSREACH (NCT05145933)
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Mathematica Policy Research, Inc.
Basal Cell Carcinoma
Topical Vitamin C for Treatment of Basal Cell Cancer
Randomized coomparative trial of a 30% solution of ascorbic acid in 95% dimethylsulfoxide applied topically twice a day for 8 weeks vs 5% imiquimod cream in the treatment biopsy proven basal cell carcinomas inotherwise healthy…
- Trial name
- NCT04279535
- Testing
- Topical Ascorbic Acid
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Center for Biomedical Research, Inc.
Depression
Adherence to Antidepressant Treatment in Subjects With Depression
This study aims to determine whether a combination a first-line antidepressant plus "RT2CK17" in a capsule relative to a first-line antidepressant plus placebo in a capsule results in higher rates of medication adherence in…
- Trial name
- NCT03388164
- Testing
- Escitalopram + RT2CK17
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Dermatitis, Atopic
Different Application Rates of Crisaborole Ointment 2% in Adults With Mild to Moderate Atopic Dermatitis
This study is being conducted to evaluate the efficacy and safety of 3 different application rates of topically applied Crisaborole ointment 2% over vehicle in adults with mild to moderate atopic dermatitis (AD).
- Trial name
- NCT03868098
- Testing
- Crisaborole 2%
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Innovaderm Research Inc.
Adolescent With Early Life Stress, Resilience
Mindfulness for Resilience in Early Life
Early life stress (ELS) is associated with a number of psychiatric and medical conditions later in life, thought to be caused by subsequent disruptions in biological processes involved in regulation of stress responses.
- Trial name
- MindREaL (NCT03633903)
- Testing
- Mindfulness
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Coronavirus
COVID-19 Health Messaging to Underserved Communities
Recent data have shown that covid19 is disproportionately infecting and killing African Americans and Latinx people in the United States.
- Trial name
- NCT04371419
- Testing
- Messaging
- Where
- United States
- Volunteers
- 14,267 people, healthy volunteers welcome
- Sponsor
- National Bureau of Economic Research, Inc.
Covid19
Covid-19 Messaging to Underserved Communities - 2nd Experiment
The aim of the study is to build off results from our first experiment (NCT04371419) , and test whether messages that acknowledge racial injustice on behalf of institutions affect the retention of knowledge and movement of…
- Trial name
- NCT04502056
- Testing
- Acknowledgement Racial Injustice AMA, African American Sender Acknowledgement, African American Sender in Informational Videos.
- Where
- United States
- Volunteers
- 20,460 people, healthy volunteers welcome
- Sponsor
- National Bureau of Economic Research, Inc.
Early Head Start Participation
The Early Head Start Family and Child Experiences Survey (Baby FACES 2018)
Early Head Start (EHS) Family and Child Experiences Survey - 2018 (Baby FACES 2018) will answer new questions about EHS programs, staff, and families that can guide program technical assistance, management, and policy.
- Trial name
- BabyFACES18 (NCT04897789)
- Where
- United States
- Volunteers
- 6,723 people
- Sponsor
- Mathematica Policy Research, Inc.
Teen Pregnancy Prevention
Evaluation of the Making Proud Choices! Teen Pregnancy Prevention Program
Under contract to the Office of Population Affairs (OPA), Mathematica is conducting an impact study of the Making Proud Choices! (MPC) teen pregnancy prevention program.
- Trial name
- NCT04863326
- Testing
- Making Proud Choices, Business as usual
- Volunteers
- 2,810 people
- Sponsor
- Mathematica Policy Research, Inc.
Metastatic Breast Cancer
A Trial of Standard Chemotherapy With Metformin (vs Placebo) in Women With Metastatic Breast Cancer
The purpose of this study is to determine if the addition of metformin to standard chemotherapy improves progression free survival in women with metastatic breast cancer.
- Trial name
- NCT01310231
- Testing
- Metformin
- Where
- 5 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Ozmosis Research Inc.
Marriage, Family Relations
Testing the Effectiveness of Integrating Relationship Education Into an Existing Workforce Readiness Program
The project will test the strategy of integrating 25 hours of relationship education into an existing employment program for low-income individuals ages 18-30.
- Trial name
- NCT02829411
- Testing
- Workforce Readiness Program, Relationship education
- Where
- United States
- Volunteers
- 909 people, healthy volunteers welcome
- Sponsor
- Mathematica Policy Research, Inc.
Teen Pregnancy Prevention
Impacts of the Positive Youth Development Program for Expectant and Parenting Teens in California
Under contract to the U.S. Department of Health and Human Services (DHHS), Mathematica is conducting an impact study of California Department of Public Health, Center for Family Health, Maternal, Child and Adolescent Health's…
- Trial name
- NCT04181034
- Testing
- Adolescent Family Life Program Positive Youth Development (PYD) program, Adolescent Family Life Program (AFLP)
- Where
- 13 sites in United States
- Volunteers
- 1,330 people
- Sponsor
- Mathematica Policy Research, Inc.
Breast Cancer, Abnormal Mammogram, Unspecified
Breath Test to Predict Breast Cancer and Outcome of Mammography
To validate a breath test that predicts risk of breast cancer and an abnormal mammogram.
- Trial name
- NCT04755829
- Testing
- BreathX test for breath VOCs
- Where
- 3 sites in Germany, Netherlands and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Menssana Research, Inc.
Family Relations, Marriage
Testing the Effectiveness of Behavioral Text Messages to Promote Attendance at HMRE Sessions
The University of Florida offers relationship education programs named ELEVATE, for couples, and Smart Steps, for couples in stepfamilies, in Citrus, Duval, Manatee, Palm Beach, and Santa Rosa counties.
- Trial name
- NCT02787460
- Testing
- Behavioral Text Messages
- Where
- United States
- Volunteers
- 1,904 people, healthy volunteers welcome
- Sponsor
- Mathematica Policy Research, Inc.