Clinical trials: sponsored by Rush University Medical Center
Coronary Artery Disease
The Impact of the Routine Aminophylline Administration Following Regadenoson Stress on SPECT Myocardial Perfusion
The investigators developed a modified regadenoson nuclear stress test of the heart that incorporates an aminophylline injection following regadenoson (The ASSUAGE protocol).
- Trial name
- ASSUAGE-MPI (NCT01655524)
- Testing
- ASSUAGE Protocol
- Where
- United States
- Sponsor
- Rush University Medical Center
Major Depressive Disorder
The Relationship Among Changes in Brain Network Activation in Adult Outpatients With Major Depressive Disorder
The purpose of this study is to explore patterns of Brain Network Activation (BNA) changes from baseline to endpoint on 1) efficacy of core symptoms of Major Depressive Disorder (MDD) and 2) improvement of cognitive dysfunction…
- Trial name
- NCT02749721
- Testing
- vortioxetine
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Rush University Medical Center
Cardiovascular Morbidity, Risk Reduction
Help Everyone Assess Risk Today: LEnten Nutrition Study (HEART-LENS)
The purpose of this study is to evaluate the impact of community health screening, health education and nutritional intervention on risk factors for cardiovascular disease in a predominantly African American population.
- Conditions
- Cardiovascular Morbidity, Risk Reduction, Nutrition Disorders
- Trial name
- NCT05057650
- Testing
- Vegan diet
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Shoulder Pain, Opioid Use
Multimodal Analgesia in Shoulder Arthroplasty
Opioid medications are associated with many side effects and the risk of abuse or overdose. Orthopaedic surgeons are currently investigating ways to control pain after surgery while limiting the amount of opioid medications…
- Trial name
- NCT03586934
- Testing
- Acetaminophen, Celecoxib 200mg, Celecoxib 400 mg
- Where
- United States
- Sponsor
- Rush University Medical Center
Persistent Postsurgical Pain
Risk Factors and Mechanisms for Persistent Postsurgical Pain After Total Knee Replacement
Osteoarthritis (OA) is the single most common cause of disability in mid and late life. About 27 million people in the United States suffer from this incurable process and 10 million have OA of the knee.
- Trial name
- PPP-TKA (NCT01320150)
- Where
- United States
- Volunteers
- 311 people
- Sponsor
- Rush University Medical Center
Biceps Tendonitis
Analysis of Suprapectoral and Subpectoral Biceps Tenodesis
Biceps pathology typically includes pain in the anterior shoulder that is reproduced with provocative maneuvers. However, optimal treatment of patient with this diagnosis is not clear and can include tenotomy (cutting the biceps)…
- Trial name
- NCT02192073
- Testing
- Suprapectoral Biceps tenodesis, Subpectoral biceps tenodesis
- Where
- United States
- Sponsor
- Rush University Medical Center
Degenerative Disc Disease, Cervical Spine Degeneration
Stand-Alone Cage Verus Anterior Plating for Anterior Cervical Discectomy and Fusion.
The purpose of this study is to compare the clinical results between two different techniques for ACDF: 1. Stand-alone ACDF, which means the placement of an interbody device (cage) without anterior fixation or plating; 2.
- Trial name
- NCT03312192
- Testing
- Interbody Cage, Interbody Cage and Anterior Plating
- Where
- United States
- Sponsor
- Rush University Medical Center
Metabolic Syndrome, Obesity
Virtual Enhanced Lifestyle for Metabolic Syndrome (ELM) Proof-of-Concept Study
This is a proof-of-concept study of a virtual version of a lifestyle intervention aimed at reducing cardiometabolic risk in patients with the Metabolic Syndrome (MetS).
- Trial name
- NCT04637477
- Testing
- Virtual ELM
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Parkinson Disease, Telemedicine
Telerehabilitation for Parkinson's Disease
Our primary objective in this 10-week pilot study is to demonstrate the feasibility of using videoconferencing technology to provide Parkinson's Disease (PD) patients, alongside their supervising care partners, specialized…
- Trial name
- TelerehabPD (NCT04600011)
- Testing
- Physical and occupational therapy (PT/OT), Home Safety Evaluation (HSE)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Rush University Medical Center
Degenerative Spinal Cord Disease
Single-Level TLIF: Post-Fusion Rehabilitation
This investigation will assess how the timing and type of rehabilitation after a transforaminal lumbar interbody fusion will affect the efficacy of the surgical procedure.
- Trial name
- NCT03033212
- Testing
- Therapist-Guided Rehabilitation, Self-Guided Rehabilitation
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Rush University Medical Center
Surgery, Arthroscopic, Analgesia
Preoperative Fluoroscopy Guided Hip Articular Branch Blocks and Analgesic Outcomes Following Hip Arthroscopy
Arthroscopic hip surgeries are increasingly being performed as both diagnostic and therapeutic interventions. These procedures are considerably painful, thus requiring the proper pain management techniques in order to provide…
- Conditions
- Surgery, Arthroscopic, Analgesia, Pain, Acute
- Trial name
- NCT04538105
- Testing
- Control, Articular Branch Block (ABB)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Anal Fistula, Rectal Fistula
A Prospective Evaluation of the Strattice-LIFT to Treat Anal Fistula
This clinical trial will evaluate the safety and efficacy of the Strattice-LIFT procedure to treat anal fistulas.
- Conditions
- Anal Fistula, Rectal Fistula, Fistula in Ano, Transsphincteric Fistula
- Trial name
- NCT02423330
- Testing
- Strattice-LIFT
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Rush University Medical Center
Opioid Use and Disposal
Impacting the Disposal of Unused Opioid
The purpose of this study is to compare the rates of proper opioid disposal in patients receiving an educational brochure compared to an automated text message delivered directly to patients' cell phones alongside the brochure…
- Trial name
- NCT04044105
- Testing
- Pamphlet education, Pamphlet education + texts
- Where
- United States
- Volunteers
- 563 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Prosthesis-Related Infections
Oral Antibiotics After 2-Stage Revision for Infected Total Hip Arthroplasty and Total Knee Arthroplasty
The primary purpose of this study is to compare the re-infection rates in patients undergoing 2-stage revision arthroplasty who receive additional oral antibiotic therapy to those patients who received in-hospital perioperative…
- Trial name
- NCT01760863
- Testing
- Oral Antibiotics
- Where
- 4 sites in United States
- Volunteers
- 185 people
- Sponsor
- Rush University Medical Center
Infection
The Effect of Oral Antibiotics on Synovial Fluid and Differential for the Diagnosis of Infection
Periprosthetic joint infection following total hip or knee arthroplasty is a rare but potentially devastating complication. Accurate diagnosis of these infections remains one of the most challenging undertakings in orthopaedics.
- Trial name
- NCT03551847
- Testing
- Antibiotic, No antibiotics
- Where
- United States
- Sponsor
- Rush University Medical Center
Prosthesis-Related Infections, Arthroplasty
Dilute Betadine Lavage in the Prevention of Postoperative Infection
The purpose of this study is to examine the efficacy of a dilute betadine solution in reducing infectious complications in revision total knee arthroplasty.
- Trial name
- NCT01175044
- Testing
- Betadine Lavage, Saline Lavage
- Where
- 2 sites in United States
- Volunteers
- 505 people
- Sponsor
- Rush University Medical Center
Parkinson Disease
High Order Spectral Analysis of Local Field Potential Data on a Subgroup of Parkinson's Disease Patients Who Are Carriers of Mutations in the Glucocerebrosidase (GBA) Gene Undergoing DBS Electrode Placement
The aim is to study a specific group of PD patients, carriers of mutations in the glucocerebrosidase (GBA) gene, which is the most common genetic risk factor for PD and is a harbinger of aggressive cognitive and motor decline.
- Trial name
- NCT04268030
- Testing
- collection of LFPs
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rush University Medical Center
Anxiety, Depression
Using CBT to Probe Psychobiobehavioral Resilience to Post-trauma Psychopathology
This randomized controlled trial uses a modularized cognitive behavioral resilience training (MCBRT) intervention to probe risk and resilience mechanisms linked to post-trauma psychopathology.
- Trial name
- NCT02279290
- Testing
- Healthy Mind Intervention (HMI), Healthy Body Intervention (HBI)
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Rush University Medical Center
Joint Pain, Trouble Balancing
Study of an Orthotic Designed to Equalize Leg Lengths for Patients With Injuries Managed in Walking Boots
Patients who undergo foot and ankle surgery are often made weight-bearing as tolerated (WBAT) in a controlled ankle movement (CAM) boot during their recovery and rehabilitation process.
- Trial name
- NCT03848949
- Testing
- Evenup
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Rush University Medical Center
Crohn's Disease, Inflammatory Bowel Disease
Dietary Treatment of Crohn's Disease
Our objective is to determine whether a specific dietary intervention or a fructooligosaccharide (FOS) supplement has anti-oxidant or prebiotic effects and whether it is beneficial in the treatment of Crohn's Disease (CD.
- Trial name
- NCT00343642
- Testing
- Active fructo-oligosaccharide, Diet
- Where
- 2 sites in United States
- Volunteers
- 73 people
- Sponsor
- Rush University Medical Center