Clinical trials: sponsored by Seattle Children's Hospital
Cancer, Acute Lymphoblastic Leukemia
A Pilot RCT of the PRISM Intervention for AYAs With Cancer
Study Title: A Pilot Randomized Controlled Trial of the Promoting Resilience in Stress Management (PRISM) Intervention for Adolescents and Young Adults with Cancer Study Population and Sample Size: Two cohorts of Adolescent and…
- Conditions
- Cancer, Acute Lymphoblastic Leukemia, Lymphoma, Sarcoma
- Trial name
- NCT02340884
- Testing
- Promoting Resilience In Stress Management (PRISM)
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Seattle Children's Hospital
Respect, Trust
Better Research Interactions for Every Family
This is a study of the feasibility of implementing a modified recruitment approach, the Better Research Interactions for Every Family (BRIEF) Intervention, within a neonatal clinical trial.
- Conditions
- Respect, Trust, Study Enrollment
- Trial name
- BRIEF (NCT04152603)
- Testing
- BRIEF Educational Module
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Sepsis, Non-Infectious Systemic Inflammatory Response Syndrome
Gene Expression Objective Definition of Early Sepsis In Children
GEODESIC is a prospective descriptive cohort investigation that will examine the generalizability of the novel host gene expression biomarkers, SeptiCyteTM LAB, SeptiCyteTM VIRUS, SeptiCyteTM BACT, and SeptiCyteTM TRIAGE…
- Trial name
- GEODESIC (NCT06231862)
- Testing
- SeptiCyte (various)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Seattle Children's Hospital
Type 1 Diabetes
Social Media Use in Adolescent Diabetes Care
The goal of this clinical trial is to evaluate the feasibility of a social media intervention to support diabetes management in adolescents with type 1 diabetes.
- Trial name
- NCT06085339
- Testing
- Social Media
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Seattle Children's Hospital
Sickle Cell Disease
iCanCope With Sickle Cell Pain
The project will test a tailored web and smartphone-based application (iCanCope with SCD) to improve pain self-management and functioning in youth (aged 12-18) with sickle cell disease.
- Trial name
- NCT03201874
- Testing
- Pain self-management, Education
- Where
- 4 sites in United States, Canada
- Volunteers
- 137 people
- Sponsor
- Seattle Children's Hospital
Asthma in Children
The RECORD-ED Pilot Study
In this pilot randomized trial, the investigators will evaluate the feasibility, acceptability, and potential family-centered outcomes associated with providing asthma discharge instructions in audio-recorded format in addition…
- Trial name
- NCT04676490
- Testing
- RECORD-ED Card, RECORD-ED Patient Portal
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Seattle Children's Hospital
Autism, Early Intervention
Implementation Toolkit to Enhance EBP Among Marginalized Families
Although the efficacy of early intervention (EI) for autistic children and their families has been established, many marginalized families with diverse cultural and linguistic backgrounds still report inequitable access to…
- Trial name
- NCT06080087
- Testing
- I-TEAM
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Preventive Health Services, Health Promotion
Well-Child Care Clinical Practice Redesign: A Parent Coach-Led Model of Care
Parent-focused Redesign for Encounters, Newborns to Toddlers (PARENT) is a team-based approach to care using a health educator ("Parent Coach") to provide the bulk of WCC services, address specific needs faced by families in…
- Trial name
- NCT03797898
- Testing
- Parent Coach
- Where
- 2 sites in United States
- Volunteers
- 937 people
- Sponsor
- Seattle Children's Hospital
Autism Spectrum Disorder, Disruptive Behavior
RUBIES in Educational Settings
The proposed three-year pilot randomized trial aims to test the effectiveness of the newly-redesigned paraeducator-delivered RUBI for use in Educational Settings (RUBIES) intervention compared to usual care training in reducing…
- Trial name
- RUBIES (NCT05093686)
- Testing
- RUBIES, Usual Care Training
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Attention Deficit Hyperactivity Disorder
Lifestyle Enhancement for ADHD Program 2
The purpose of this study is to increase physical activity (PA) in children with ADHD using a novel, family-based intervention that promotes PA within the context of evidence-based behavioral management training (BMT) for…
- Trial name
- LEAP (NCT04779333)
- Testing
- LEAP, Standard BMT
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Epilepsy Intractable
ABI-009 (Nab-rapamycin) for Surgically-Refractory Epilepsy (RaSuRE)
This is a prospective, single-center, phase 1 safety study to investigate the safety, tolerability, seizure control, and quality of life in participants with medically-refractory epilepsy who failed epilepsy surgery.
- Trial name
- NCT03646240
- Testing
- ABI-009
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Seattle Children's Hospital
Risk Reduction Behavior
Assessing Health Electronically for Adolescent and Young Adult Oncology
The purpose of this study is to modify an existing Seattle Children's Hospital investigator-developed, patient-centered, electronic health assessment (eHA) called "Check Yourself" for AYAs with cancer.
- Trial name
- AHEAD (NCT04484194)
- Testing
- Check Yourself - Oncology
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Seattle Children's Hospital
Autism Spectrum Disorder
Training and Implementation of RUBI in Community Mental Health Settings
This project is focused on evaluating outcomes related to this statewide clinical training effort in the RUBI parent training program.
- Trial name
- NCT05742464
- Testing
- RUBI
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Septic Shock
Life After Pediatric Sepsis Evaluation
Sepsis represents the leading cause of childhood mortality worldwide. However, as distinct from adult medicine, there exists a large knowledge gap regarding long term health related quality of life (HRQL) and functional status…
- Trial name
- LAPSE (NCT01415180)
- Where
- 11 sites in United States
- Volunteers
- 389 people
- Sponsor
- Seattle Children's Hospital
Safety
Developing a Dyadic Shared Decision Making Tool About Firearm Storage
Given that firearm ownership is legal, common, and valued by many people in the U.S, safe storage is important to minimize the risk of unauthorized access, injury and death.
- Trial name
- NCT05451355
- Testing
- Family Safety Check-In, AAP Firearm Storage Web Page
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Health Care Utilization
Surgical Patient Education in Pediatric Urology
Randomized study to assess the impact of supplemental educational YouTube videos on postoperative healthcare utilization following ambulatory pediatric urologic surgery
- Trial name
- Uro Surg HL (NCT05597449)
- Testing
- YouTube videos on care after urologic surgery
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Substance Use Disorders, Recidivism
Preventing OUD in Justice-Involved Youth
The United States is experiencing an opioid epidemic. Sadly, opioid-related fatalities are on the rise, causing profound emotional, financial, and cultural impacts.
- Trial name
- POST (NCT04901312)
- Testing
- Adolescent Community Reinforcement Approach, Assertive Continuing Care, Trauma Affect Regulation Guide for Education and Therapy
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- Seattle Children's Hospital
Chronic Pain, Central Sensitisation
Mechanisms Of Change in Adolescent Pain Self-management
The MOCAS Study aims to describe the mechanisms through which sleep deficiency affects youth responses to an online pain self-management intervention over a 6-month period.
- Conditions
- Chronic Pain, Central Sensitisation, Headache
- Trial name
- MOCAS (NCT04043962)
- Testing
- Web-based CBT (Web-MAP)
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Seattle Children's Hospital
Hypothalamic Obesity
Energy Balance & Weight Loss in Craniopharyngioma-related or Other Hypothalamic Tumors in Hypothalamic Obesity
The proposed multicenter study will test the effect of glucagon-like peptide (GLP)-1 agonist exenatide once weekly extended-release (ExQW, Bydureon®) on clinical outcomes and metabolic parameters in a double-blind…
- Trial name
- ECHO (NCT02664441)
- Testing
- Exenatide
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Seattle Children's Hospital
Mental Health Disorders, Suicide or Selfinflicted Injury by Firearms and Explosives
Firearm Storage Device Distribution to Families of Children With Mental Health Complaints
This study aims to describe the baseline rate of safe firearm storage device use in the homes of pediatric patients with mental health complaints treated in the Emergency Department (ED) and/or inpatient psychiatric unit of an…
- Trial name
- NCT03386409
- Testing
- Free safe firearm storage device distribution, Low cost safe firearm storage device
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- Seattle Children's Hospital