Clinical trials: sponsored by Sir Run Run Shaw Hospital
Penile Amputation
Replantation Following Complete Penile Amputation
The goal of this observational study Replantation following Complete Penile Amputation a case series before and after study is to help andrologist and urologists deal with such rare male emergencies easily in emergency situation.
- Trial name
- NCT06244927
- Testing
- Replantation surgery
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Sir Run Run Shaw Hospital
Type 2 Diabetes, Non-Alcoholic Fatty Liver Disease
Henagliflozin in Relieving Type 2 Diabetes With Non-alcoholic Fatty Liver Disease
This study is a randomized, non-blinded clinical trial specifically designed to assess the initial feasibility and efficacy of SGLT2 inhibitors in treating NAFLD among adults diagnosed with type 2 diabetes.
- Trial name
- NCT06218342
- Testing
- Henagliflozin, Background medication
- Volunteers
- 156 people
- Sponsor
- Sir Run Run Shaw Hospital
Cigarette Smoking, Smartphone App-based Smoking Cessation
Efficacy of Smartphone App for Smoking Cessation in China
This study aims to evaluate the efficacy of cognitive behavioral therapy (CBT)-based cigarette smoking cessation smartphone app for treatment seeking smokers in China.
- Trial name
- NCT04421170
- Testing
- smartphone app for smoking cessation
- Where
- China
- Volunteers
- 1,289 people
- Sponsor
- Sir Run Run Shaw Hospital
Major Depressive Disorder
Prospective Clinical Cohort Study of Depression
This is a prospective clinical cohort study of depression. The study was intended to include 300 patients with depression and 100 healthy controls.
- Trial name
- NCT05775809
- Testing
- selective serotonin reuptake inhibitors, TMS
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Healthy
Molecular Basis of Loss Aversion
The goal of this clinical trial is to test the roles of dopamine and norepinephrine in decision making related to loss aversion in the healthy population.
- Trial name
- NCT06034158
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Digestive System Neoplasms
Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Subjects With Resected Digestive System Neoplasms
The purpose of this study is to assess the safety, feasibility, and efficacy of personalized mRNA vaccine iNeo-Vac-R01 with standard adjuvant therapy in subjects with surgically resected digestive system neoplasms.
- Trial name
- NCT06026774
- Testing
- iNeo-Vac-R01 in combination with standard adjuvant therapy
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Sir Run Run Shaw Hospital
Digestive System Neoplasms
Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Combination With Standard First-line Treatment in Subjects With Advanced Digestive System Neoplasms
The purpose of this study is to assess the safety, feasibility, and efficacy of personalized mRNA vaccine iNeo-Vac-R01 in combination with first-line treatment in subjects with advanced digestive system neoplasms.
- Trial name
- NCT06026800
- Testing
- iNeo-Vac-R01
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Sir Run Run Shaw Hospital
Catheter Complications
An Exploratory Study of Perioperative Venous Access in Obese Patients
This study is intended to explore the application effect of long peripheral intravenous catheters(LPCs) and midline catheters(MCs) in the perioperative period of obese patients, aiming at providing the scientific basis for the…
- Trial name
- NCT06031545
- Testing
- Long peripheral venous catheters for use, Midline catheter
- Where
- China
- Volunteers
- 528 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Digestive System Neoplasms
Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen Alone in Subjects With Advanced Digestive System Neoplasms
The purpose of this study is to assess the safety, feasibility, and efficacy of personalized mRNA vaccine iNeo-Vac-R01 alone in subjects with advanced digestive system neoplasms.
- Trial name
- NCT06019702
- Testing
- iNeo-Vac-R01
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Sir Run Run Shaw Hospital
Cigarette Smoking, Psychological Interventions
Efficacy and Neuroimaging Mechanisms of Smoking Cessation in China
This proposed project is to assess the efficacy of CBT-based digital smoking cessation interventions in China, as well as explore its neuroimaging mechanisms.
- Conditions
- Cigarette Smoking, Psychological Interventions, Smoking Cessation
- Trial name
- NCT05788068
- Testing
- Cognitive behavior therapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Sir Run Run Shaw Hospital
Rectal Cancer
Total Neoadjuvant Therapy With Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Ultra Low Rectal Adenocarcinoma
Short-course radiotherapy combined with immunotherapy may bring revolutionary changes to the total neoadjuvant therapy mode for locally advanced ultra low rectal cancer to preserve the organs.
- Trial name
- RECMULRA-TNT (NCT05858567)
- Testing
- Envafolimab
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sir Run Run Shaw Hospital
Infection
A Multicentre Pilot Study of Midline Catheter's Tip at a Different Position in Antimicrobial Therapy
The research protocol was based on assigning patients to three different catheter tip groups and then observing the relationship between the tip and catheter-related complications when infusing antimicrobial agents.
- Trial name
- NCT04601597
- Testing
- Shu Bei Kang (China) Midline Catheters
- Where
- 6 sites in China
- Volunteers
- 330 people
- Sponsor
- Sir Run Run Shaw Hospital
Catheter Complications
Application Study of Infusing Irritant Medications Through Midline Catheter Based on Real World Study
The goal of this observational study is to learn about the effect on midline catheter outcomes when infusing irritant medications through midline catheter.
- Trial name
- NCT05710835
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Sir Run Run Shaw Hospital
Cigarette Smoking, Smoking Cessation
'WeChat WeQuit' Smoking Cessation Program
This proposed project is to assess whether WeChat-based smoking cessation interventions ('WeChat WeQuit' program) will be effective at helping people in China who smoke, to quit.
- Trial name
- NCT03169686
- Testing
- Cognitive and Behavioral Intervention
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Schizophrenia
Effect of Nicotine Transdermal Patch on Cognitive Function and Glycolipid Metabolism in Non-smoking Schizophrenia
Schizophrenia is a group of severe mental disorders of unknown etiology, with significant abnormalities in mental activities such as cognition, thinking, emotion, and behavior, and lead to obvious occupational and social function…
- Trial name
- NCT05301660
- Testing
- Nicotine transdermal patch
- Volunteers
- 80 people
- Sponsor
- Sir Run Run Shaw Hospital
Advanced Malignant Solid Tumor
Clinical Study of a Personalized Neoantigen Cancer Vaccine in Treating Patients With Advanced Malignant Tumor
This research study is evaluating a new type of cancer vaccine called "Personalized Neoantigen Cancer Vaccine" as a possible treatment for advanced malignant tumor.
- Trial name
- NCT03662815
- Testing
- iNeo-Vac-P01, GM-CSF
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sir Run Run Shaw Hospital
Hematological Diseases, Carbapenem-resistant Enterobacteriaceae
Carbapenem-resistant Organisms (CRO) Screening From Rectal Swabs in Patients With Hematological Diseases in China
Carbapenem-resistant Organisms (CRO) include Carbapenem-resistant Enterobacteriaceae (CRE), Carbapenem-resistant Pseudomonas aeruginosa (CRPA) and Carbapenem-resistant Acinetobacter baumannii (CRAB).
- Conditions
- Hematological Diseases, Carbapenem-resistant Enterobacteriaceae, Carbapenem-resistant Pseudomonas Aeruginosa, Carbapenem-resistant Acinetobacter Baumannii
- Trial name
- CROSS (NCT05002582)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Sir Run Run Shaw Hospital
Advanced Malignant Solid Tumor
Clinical Study of a Personalized Neoantigen Cancer Vaccine Combined With Anti-PD-1 and RFA in Patients With Solid Tumors
This research study is evaluating a new type of personalized neoantigen cancer vaccine（iNeo-Vac-P01）combined with anti-PD-1 antibody and radiofrequency ablation as a possible treatment for patients with advanced solid tumors.
- Trial name
- NCT04864379
- Testing
- iNeo-Vac-P01, GM-CSF, PD-1
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sir Run Run Shaw Hospital
Thin Endometrium, Intrauterine Adhesion
Clinical Study of Umbilical Cord Mesenchymal Stem Cells Combined With Collagen Scaffold in the Treatment of Thin Endometrium
This is a non-blind self-control trial. We mainly compare the changes of endometrial thickness，changes in menstrual flow, and improvement in pregnancy before and after stem cell treatment in patients with thin endometrium.
- Trial name
- NCT03724617
- Testing
- umbilical cord mesenchymal stem cells combined with collagen scaffold
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Sir Run Run Shaw Hospital
Face-touching Behavior
Mindfulness-based "STOP (Stop, Take a Breath, Observe, Proceed) Touching Your Face" Intervention
This single-blind, randomized, controlled, trial is to assess the efficasy of a brief mindfulness-based "STOP touching your face" training program to reduce or avoid face-touching to low people's chances of catching infectious…
- Trial name
- NCT04330352
- Testing
- Mindfulness-based "STOP touching your face" practice
- Where
- China
- Volunteers
- 1,094 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital