Clinical trials: sponsored by Tongji Hospital
Ovarian Cancer, Postoperative Complications
Systematic Lymphadenectomy During Interval Debulking Surgery in Advanced Epithelial Ovarian Cancer
The study aims to investigate the prognostic and postoperative complication relevance of lymphadenectomy in advanced epithelial ovarian cancer patients who received neoadjuvant chemotherapy (NACT) followed by interval debulking…
- Conditions
- Ovarian Cancer, Postoperative Complications, Neoadjuvant Therapy, Lymph Node Excision
- Trial name
- NCT06385912
- Testing
- lymphadenectomy
- Where
- China
- Volunteers
- 1,090 people
- Sponsor
- Tongji Hospital
RSV Infection
Epidemiological and Clinical Characteristics of Hospitalized Patients Under 5 Years Old With RSV Infection in Central China, Wuhan
The study will be a multicenter, hospital-based retrospective study. We plan to collect the clinical and laboratory data among all hospitalized ARTI cases in three hospitals in Wuhan from June 1, 2020 to May 31, 2023 and then…
- Trial name
- NCT05767294
- Testing
- Observation
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Tongji Hospital
B Cell Malignancies
Anti-CD19-CAR-T Cells in Relapsed/Refractory B-cell Tumor Patients.
This study is a single-center, open-label, single-dose clinical trial of anti-CD19-CAR-T cell therapy in relapsed/refractory B-cell tumor patients after Qinglin pre-treatment.
- Trial name
- NCT06375161
- Testing
- anti-CD19-CAR-T cells
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Breast Cancer
Adebrelimab Combined With Dalpiciclib and Standard Endocrine Therapy for HR+/HER2 - Advanced Breast Cancer
This is a prospective, single-arm, multicenter Phase II study of patients with advanced HR+/HER2- breast cancer who are untreated or have failed previous first-line endocrine therapy。The primary objective of this study was to…
- Trial name
- NCT06149130
- Testing
- Adebrelimab, dalpiciclib
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Tongji Hospital
Coronary Disease
Evaluation of Plasma Non-coding RNAs as Biomarkers in Coronary Heart Disease
The purpose of this study is to determine whether the expression level of miR-320a are effective as biomarker in evaluating the diagnosis, prognosis and treatment effects of coronary heart disease.
- Trial name
- NCT02751060
- Testing
- No intervention
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Tongji Hospital
Prognosis, Sequelae
Longitudinal Changes in Characteristics of COVID-19 Survivors and Their Long-term Follow-up Study
Follow-up study of Coronavirus disease 2019 (COVID-19) survivors has rarely been reported. We aimed to investigate longitudinal changes in the characteristics of COVID-19 survivors after discharge.
- Trial name
- NCT05004246
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Tongji Hospital
Liquid Biopsy, Endometriosis
A Liquid Biopsy Diagnostic Techniques for Endometriosis
To evaluate the diagnostic efficiency of circulating endometrial cell detection method using microfluidic chip as an non-invasive method for diagnosis in endometriosis.
- Trial name
- NCT05749341
- Testing
- Three-Dimensional Poly(dimethylsiloxane) Scaffold
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Tongji Hospital
Ovarian Aging
A Multicenter Clinical Study of Yijing Keli in the Treatment of Ovarian Aging
Ovarian aging (OA) seriously affects the physical and mental health of women. Nowadays, Chinese herbs have huge appeal and potential in treating OA.
- Trial name
- NCT06271928
- Testing
- Yijing Keli
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital
Lung Cancer, Pulmonary Nodule, Solitary
Application of Carbon Dioxide for Identifying the Intersegmental Plane in Thoracoscopic Segmentectomy
With the increasing acceptance of routine computed tomography (CT) screenings, early-stage lung cancer detection is becoming more frequent.
- Conditions
- Lung Cancer, Pulmonary Nodule, Solitary, Segmentectomy, Pulmonary Nodule, Multiple
- Trial name
- NCT05350137
- Testing
- 100% oxygen, Carbon dioxide
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Tongji Hospital
Ovarian Aging
A Clinical Study of Baozhu Keli in the Treatment of Ovarian Aging
Ovarian aging (OA) seriously affects the physical and mental health of women. Nowadays, Chinese herbs have huge appeal and potential in treating OA.
- Trial name
- NCT06256783
- Testing
- Baozhu Keli
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital
Dilated Cardiomyopathy, Kaposi's Sarcoma-Associated Herpesvirus Infection
The Effects of Sirolimus in Patients With Dilated Cardiomyopathy Infected With Kaposi Sarcoma-associated Virus
Evaluating the efficacy of sirolimus (compared to standard therapy alone) in the treatment of dilated cardiomyopathy infected with Kaposi Sarcoma-associated virus -- a multicenter randomized controlled study.
- Trial name
- SDCMK (NCT06236022)
- Testing
- Sirolimus
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Tongji Hospital
Laryngopharyngeal Reflux
Clinical Study of Jinsang Liyan Capsules Combined With PPI in the Treatment of LPRD
The goal of this clinical trial is to compare the efficacy of Jinsang Liyan capsule in combination with PPI versus PPI alone for the treatment of Laryngopharyngeal Reflux Disease (LPRD).
- Trial name
- NCT05879029
- Testing
- Jinsang Liyan Capsule; Rabeprazole enteric-coated tablets.
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Tongji Hospital
Cholangiocarcinoma Non-resectable
Combined DEB-TACE, Lenvatinib and Pucotenlimab as Conversion Therapy for Unresectable Intrahepatic Cholangiocarcinoma
This is an open-label, single-arm, phase 2 study. The purpose of study is to evaluate the feasibility and safety of drug eluting beads-transcatheter arterial chemoembolization combined with lenvatinib and pucotenlimab as…
- Trial name
- CCGLC-012 (NCT06192784)
- Testing
- DEB-TACE, Lenvatinib plus pucotenlimab
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Tongji Hospital
Atrial Fibrillation
Three Dimensional Navigation IntraCardiac Guidance Kit for Atrial Septal Puncture
This study aims to evaluate the safety and efficacy of a three-dimensional navigation intracardiac guidance kit to perform atrial septal puncture in patients requiring catheter ablation, which will be compared with procedures…
- Trial name
- NCT06188351
- Testing
- Three-Dimensional Navigation Atrial Septal Puncture, Conventional Atrial Septal Puncture
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Tongji Hospital
Hepatocellular Carcinoma
PVE/PVL Combined With DEB-TACE in the Treatment of Patients With Large and Unresectable Liver Cancer
This is a multicenter, randomized, positive parallel controlled clinical study to evaluate the short-term and long-term efficacy and safety of PVL/PVE combined with DEB-TACE in the treatment of unresectable patients with large or…
- Trial name
- CCGLC-004 (NCT05103007)
- Testing
- DEB-TACE, PVL/PVE+DEB-TACE
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Hepatocellular Carcinoma, Biliary Tract Neoplasms
Primary Hepatobiliary Cancer Cohort of Central China
This registry is designed as a longitudinal cohort study of patients diagnosed with primary hepatobiliary cancer in Tongji Hospital, Wuhan.
- Trial name
- CCGLC-002 (NCT05520801)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Tongji Hospital
Dental Implant
The Accuracy of Static Navigation Systems and Robotic System in Partially Edentulous in Posterior Area
The aim of this randomized clinical trial to compare the implant positional accuracy of robotic system-assisted implant surgery with that of static system-assisted implant surgery.
- Trial name
- NCT06173921
- Testing
- robotic system, Static navigation system
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Breast Cancer With Brain Metastases
Pyrotinib Combined With Capecitabine and Bevacizumab for Patients With HER2 Positive Breast Cancer and Brain Metastases
This study intends to conduct a small, prospective, single-center clinical study to explore and evaluate the efficacy and safety of pyrrotinib combined with capecitabine and bevacizumab in HER2-positive advanced breast cancer…
- Trial name
- NCT06152822
- Testing
- pyrotinib+capecitabine+bevacizumab
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Tongji Hospital
Atrial Arrhythmia, Atrial Premature Complexes
Zero Fluoroscopic Ablation Versus Conventional Fluoroscopic Ablation for Right Atrial Arrhythmias
This study is intended to compare the feasibility, safety and efficacy of a zero-fluoroscopic approach with conventional fluoroscopic approach as performing catheter ablation of right atrial arrhythmias.
- Conditions
- Atrial Arrhythmia, Atrial Premature Complexes, Atrial Tachycardia
- Trial name
- ZFA-RAA (NCT03151278)
- Testing
- Zero-fluoroscopy ablation, Conventional fluoroscopy ablation
- Where
- China
- Volunteers
- 212 people
- Sponsor
- Tongji Hospital
Paroxysmal Supraventricular Tachycardia
Zero-fluoroscopy Approach Versus Fluoroscopic Approach for the Ablation of Paroxysmal Supraventricular Tachycardia
This study is aimed to compare the feasibility, safety and efficacy of a zero-fluoroscopic approach using Ensite NavX with conventional fluoroscopic approach using Ensite NavX plus fluoroscopy for the ablation of paroxysmal…
- Trial name
- ZFA-PSVT (NCT03042078)
- Testing
- Zero-fluoroscopic ablation, Conventional fluoroscopic ablation
- Where
- China
- Volunteers
- 3,060 people
- Sponsor
- Tongji Hospital