Clinical trials: sponsored by Tongji Hospital
Postoperative Pulmonary Complications, Risk Factors
Incidence and Risk Factors of PPCs in Elderly Patients Undergoing Robot Assisted Laparoscopic Pelvic Surgery
Postoperative pulmonary complications are important factors affecting the prognosis of patients undergoing surgery. Studies have shown that patients undergoing abdominal or pelvic surgery, emergency surgery, or prolonged surgery…
- Trial name
- NCT05519657
- Volunteers
- 154 people
- Sponsor
- Tongji Hospital
Migraine, Classic
Transcutaneous Supraorbital Nerve Stimulator Versus Topiramate in Prevention of Recurrent Migraine
Migraine has been ranked as the second most disabling neurological disorder in the worldwide. Medication or nonpharmacological treatments are all reasonable options for the prevention.
- Trial name
- NCT05516251
- Testing
- Transcutaneous Supraorbital Nerve Stimulator, Topiramate 25Mg Tab
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Chronic Kidney Diseases
Human Umbilical Cord Mesenchymal Stem Cell(UC-MSC)Delayed Renal Chronic Kidney Disease(CKD3、4 )
The chronic kidney disease is caused by renal structural and functional impairment for more than 3 months due to various causes, including normal and abnormal glomerular filtration rate (GFR), abnormal blood, urine, and imaging…
- Trial name
- NCT05512988
- Testing
- UC-MSC, Saline solution
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Tongji Hospital
Colonic Neoplasms
Cetuximab in Combination With Anti-PD-1 and mFOLFOX Treat For RAS/BRAF wt Right-Sided Colon Cancer
We plan to evaluate the efficacy and safety of cetuximab combined with anti-PD-1 and mFOLFOX6 in the treatment of RAS/BRAF WT locally advanced or metastatic right colon cancer
- Trial name
- CIFOXRC (NCT05468177)
- Testing
- neoadjuvant chemotherapy
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Tongji Hospital
Difficult Airway
Evaluation of a Flexible Videoscope Training Simulator
Flexible bronchoscope or videoscope plays important roles in managing difficult airway. But this technique is time-consuming and very difficult to learn for novices.
- Trial name
- NCT05327842
- Testing
- New training simulator, Traditional simulator
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Tongji Hospital
HCC
A Novel MSE Score to Predict rHCC Patients
Develop and validate a novel scoring system based on pathological factors to predict the postoperative survival of patients with rHCC.Patients with rHCC who underwent hepatectomy were recruited from two hospitals.Exploring…
- Trial name
- NCT05450874
- Testing
- hepatectomy
- Volunteers
- 300 people
- Sponsor
- Tongji Hospital
Mental Retardation, Autism Spectrum Disorder
A Cross-sectional Study to Evaluate Speech and Language Development in Chinese Children Aged 2-6 Years
The purpose of this study is to establish a new Chinese children's speech and language norm by obtaining the latest data of speech and language development of children aged 2 ~ 6 from different regions in China.
- Conditions
- Mental Retardation, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT05442229
- Testing
- establish a new Chinese children's speech and language norm
- Volunteers
- 5,744 people
- Sponsor
- Tongji Hospital
Hepatocellular Carcinoma, Programmed Cell Death 1
Real-world Study of Efficacy and Safety of ICIs and TKIs Therapy for HCC
China is a high-risk area of Hepatocellular Carcinoma (HCC). Although Chinese population accounts for 18.4% of the global population, the number of new HCC patients accounting for about half of the global, which seriously…
- Conditions
- Hepatocellular Carcinoma, Programmed Cell Death 1, Effects of Immunotherapy
- Trial name
- NCT05420922
- Testing
- Lenvatinib Oral Product, PD-1 inhibitor, Local treatment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Tongji Hospital
HCC, Portal Hypertension
Hepatectomy for Early-stage HCC Patients With CSPH
Clinically significant portal hypertension (CSPH) can affect the surgical prognosis of early-stage (BCLC stage A) HCC. An additional stage, such as the BCLC stage A-B, can be considered.
- Trial name
- NCT05402644
- Testing
- hepatectomy
- Volunteers
- 320 people
- Sponsor
- Tongji Hospital
Paroxysmal Atrial Fibrillation
The Effect and Safety of Pulsed Field Ablation (PFA) in Patients With Paroxysmal Atrial Fibrillation (PAF)
This study is aimed to evaluate the Efficacy and Safety of Pulsed Field Ablation (PFA) in Patients with Paroxysmal Atrial Fibrillation (PAF)
- Trial name
- ESPFA-CN21 (NCT05400928)
- Testing
- Pulsed Field Ablation
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Tongji Hospital
Myelodysplastic Syndromes
Hetrombopag for Lower-risk MDS With Thrombocytopenia: a Prospective，Open-label, Single-arm Study.
The is a phase 2, single-arm, open-label clinical study assessing the efficacy and safety of hetrombopag to increase platelet count in lower-risk MDS patients with thrombocytopenia.
- Trial name
- NCT05392647
- Testing
- Hetrombopag
- Volunteers
- 28 people
- Sponsor
- Tongji Hospital
Endometrial Cancer, Cervical Stromal Invasion
Radiomics Based Multimodal Transvaginal Ultrasound Imaging in Endometrial Cancer
Retrospectively collect preoperative transvaginal B-mode ultrasound (BMUS), color Doppler flow imaging (CDFI) and three-dimensional ultrasound (3D-US) images and clinical data in patients with non-endometrial cancer diseases and…
- Conditions
- Endometrial Cancer, Cervical Stromal Invasion, Transvaginal Ultrasound
- Trial name
- NCT05387460
- Testing
- radiomics
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Tongji Hospital
Gut Microbiota, Hepatocellular Carcinoma
The Effect of Gut Microbiota on Postoperative Liver Function Recovery in Patients With Hepatocellular Carcinoma
The purpose of this study was to explore the correlation between postoperative recovery of liver function and gut microbiota in patients with hepatocellular carcinoma (HCC).
- Trial name
- NCT04303286
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Cancer
Safety and Efficacy of RD133 in Subjects With Relapsed or Refractory MSLN-Positive Solid Tumors
This study is a single-center exploratory clinical trial. It is estimated that 9-24 subjects will be enrolled. The "3+3" dose escalation design is adopted.
- Trial name
- NCT05141253
- Testing
- RD133
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Tongji Hospital
Cholangitis, Secondary Biliary, Treatment Compliance
Antibiotics Treatment of Cholangitis Post-Kasai Portoenterostomy
Application of multi-center, prospective study on the severity of postoperative cholangitis biliary atresia classification, according to the degree of cholangitis targeted therapy, to improve the therapeutic effect of…
- Conditions
- Cholangitis, Secondary Biliary, Treatment Compliance, Antibodies Drug Specific
- Trial name
- NCT04370145
- Testing
- Sulperazon, Teicoplanin, Meropenem Injection
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Tongji Hospital
Circulating Tumor Cell
Circulating Tumor Cell Detection in Hepatocellular Carcinoma
The investigators examined circulating tumor cells (CTC) in the perioperative peripheral blood of hundreds of HCC patients undergoing liver cancer surgery using CellSearch technology between 2013 and 2016.
- Trial name
- NCT05297955
- Where
- China
- Volunteers
- 458 people
- Sponsor
- Tongji Hospital
Pemphigus Vulgaris
A Study to Evaluate Efficacy and Safety of Abatacept in Participants of Pemphigus Vulgaris (PV)
Pemphigus vulgaris (PV) is a rare, chronic, debilitating, and potentially life-threatening autoimmune disorder that is characterized by mucocutaneous blisters.Abatacept is a biologic drug that belongs to the class of T-cell…
- Trial name
- NCT05303272
- Testing
- Abatacept Prefilled Syringe, Mycophenolate Mofetil 500Mg Tab
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tongji Hospital
HPV Integration
The Predictive Role of HPV Integration in HSIL and Cervical Cancer
The stratified analysis by the level of HPV DNA integration in HSIL and cervical cancer will be drawn to explore whether the status of HPV integration makes any difference in the progression of cervical cancer.
- Trial name
- NCT05300243
- Testing
- HPV integration test
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Rosai-Dorfman Disease, Langerhans Cell Histiocytosis
Central China Rosai-Dorfman Disease Registry
This is a research study among patients with Rosai-Dorfman disease.
- Trial name
- CCR-DDR (NCT05284942)
- Testing
- Mycophenolate mofetil combined with oral prednisone
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- Tongji Hospital
Vasospastic Angina
A Multi-Omics Study of Vasospastic Angina
This is a observational study to identify the key factor associated with vasospastic angina and to explore the prognosis of the participants.
- Trial name
- KIVAM (NCT05282511)
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital