Clinical trials: completed, sponsored by Universitaire Ziekenhuizen KU Leuven
Head and Neck Cancer
Dose De-escalation to the Elective Nodal Sites in Head and Neck Cancer
A randomized clinical trial was initiated to investigate whether a reduction of the dose to the elective nodal sites and the swallowing apparatus delivered by IMRT would result in a reduction of acute and late side effects…
- Trial name
- NCT01812486
- Testing
- dose de escalation, standard dose
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Blood Transfusion Events
Common Causes of Blood Transfusion Events in a University Hospital: Analysis of Incident Reports
Inhospital the blood transfusion process consists of many phases: ordering the blood product, analysis of the blood sample, delivery, transport and storage of the blood product and administration.
- Trial name
- NCT01812499
- Where
- Belgium
- Volunteers
- 131 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Effects of Strength Training in Older Adults
The Effects of Low- and High-intensity Resistance Exercise on Force-velocity Characteristics in Older Adults
The purpose of this study is to compare the impact of high- and low-intensity resistance exercise on force-velocity characteristics, muscle mass and inflammatory processes in older adults.
- Trial name
- NCT01707017
- Testing
- Strength training
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Non-cystic Fibrosis Bronchiectasis
Mortality in Non-cystic Fibrosis Bronchiectasis
In this study we analyzed the overall survival for all newly diagnosed patients with non-cystic fibrosis bronchiectasis from June 2006 onwards.
- Trial name
- NCT01792427
- Where
- Belgium
- Volunteers
- 253 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Non-cystic Fibrosis Bronchiectasis, Healthy
The Sputum Colour Chart as a Predictor of Lung Inflammation and Proteolysis in Non-cystic Fibrosis Bronchiectasis
Non-cystic fibrosis bronchiectasis patients (and controls) were recruited for the study. The investigators' aim was to study the relevance of clinical parameters in terms of underlying disease severity, proteolysis and…
- Trial name
- NCT01792440
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Open-angle Glaucoma, Low Tension Glaucoma
Waveform Analysis of the Doppler Curve of Ophthalmic Arteries in Glaucoma Patients
Color Doppler Imaging (CDI) has been providing information about ocular blood flow over the past decades. This non-invasive procedure based on ultrasound technique has identified increased resistance and decreased systolic blood…
- Trial name
- NCT01487655
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Open Angle Glaucoma, Low Tension Glaucoma
Validation of Retinal Oximetry in Glaucoma Patients: a Structural and Functional Correlation
Retinal ischemia is thought to play an important role in the pathogenesis of glaucoma. Up until today, very little is known about the metabolic alterations in the retina of glaucoma patients, since only techniques for surrogate…
- Trial name
- NCT01391247
- Where
- Belgium
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Myocardial Infarction
Bone Marrow-Derived Stem Cell Transfer in Acute Myocardial Infarctions
The benefit of reperfusion therapies for ST-elevation acute myocardial infarction (STEMI) is limited by postinfarction left ventricular (LV) dysfunction.The purpose of this study is to determine whether intracoronary transfer of…
- Trial name
- NCT00264316
- Testing
- bone marrow-derived stem cell transfer
- Where
- Belgium
- Volunteers
- 68 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Asthma
Guidance of Patients With Asthma During Preparation and During Expedition to the Aconcagua Mountain
A selection of asthma patients were followed during preparation to climb the Aconcagua mountain. The primary goal of this follow up was to optimize patients' asthma status.
- Trial name
- NCT01760928
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ageing Process, Muscle Quality
The Influence of Ageing on Muscle Quality
The purpose of the present study is to evaluate the influence of the ageing process on muscle quality. Therefore, muscle mass, muscle density and force-velocity characteristics are measured after a 5-yr interval in older adults…
- Trial name
- NCT01216917
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Training, Ageing
The Long-term Effects of Training on Muscle Strength and Functionality
The purpose of the present study is to evaluate the long-term effects of 1 year of high-intensity fitness training and low-intensity whole-body vibration training on muscle strength and functionality.
- Conditions
- Training, Ageing, Muscle Strength, Functionality
- Trial name
- NCT01682330
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Functionality, Strength
Objective Assessment of Physical Activity in Older Adults
The purpose of the present study is to evaluate the validity of 2 objective measures of physical activity among older adults. In addition, the investigators will examine the influence of functionality, walking aids, walking speed…
- Conditions
- Functionality, Strength, Validity During Daily Activities, Physical Activity
- Trial name
- NCT01621035
- Where
- Belgium
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Strength Training, Muscle Strength, Muscle Mass, Inflammatory Processes
The Role of Mechanical Stress and Muscle Fatigue in Strength Gains
The purpose of this study is to compare the impact of different levels of mechanical stress and muscle fatigue in strength training conditions on muscle strength, muscle mass and inflammatory processes.
- Trial name
- NCT01216774
- Testing
- Strength training
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Test-retest Reliability, Validity
Test-retest Reliability of a Standard Protocol on the Biodex Dynamometer
The purpose of the present study is to evaluate test-retest reliability of a standard protocol on the Biodex dynamometer in older adults.
- Conditions
- Test-retest Reliability, Validity, Biodex Medical Systems III Dynamometer, Experimental Measure of Knee Extension Strength
- Trial name
- NCT01217684
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Acute Rejection of Renal Transplant, Renal Graft Loss
Reasons for Mycophenolate Mofetil Dose Reduction and Impact on Graft Outcome in Renal Transplant Recipients
Mycophenolate mofetil (MMF) decreases the risk of acute rejection and is associated with improved graft survival in renal transplant recipients.
- Trial name
- NCT01496703
- Testing
- no intervention, this is an observational retrospective trial
- Where
- Belgium
- Volunteers
- 749 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Dialysis, Fistula
Study of Pain, Anxiety and Complications Related to Cannulation of Arteriovenous (AV) Fistula in Chronic Hemodialysis Patients
A. Pain and other disadvantages of AV fistula cannulation can be limited by using the so-called buttonhole technique. B. Till present in our center catheters with cylindrical points are used for cannulation of AV fistulas with…
- Trial name
- NCT00544492
- Testing
- catheter for AV fistula cannulation
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Prophylaxis
Cefazolin Pharmacokinetics: Elimination Clearance in Neonates
To document cefazolin disposition (concentration/time profile, protein binding, metabolism, renal elimination characteristics) and its covariates in neonates following intravenous administration of the drug at induction of…
- Trial name
- NCT01295606
- Testing
- Cefazolin
- Volunteers
- 40 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Postoperative Pain
Disposition of Intravenous Ketorolac
The purpose of this study is: to document ketorolac disposition (concentration/time profile, protein binding, metabolism) and its covariates following intravenous (iv) administration of ketorolac right after caesarean section and…
- Trial name
- NCT01291472
- Testing
- Ketorolac Tromethamine
- Where
- Belgium
- Volunteers
- 42 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Osteoid Osteoma
Treatment Outcome After Surgical Treatment of Osteoid Osteoma
Purpose of the study: To retrospectively determine the clinical results in an unselected group of consecutive patients with osteoid osteoma treated by surgery.
- Trial name
- NCT01466010
- Testing
- surgical removal of osteoid osteoma
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Idiopathic Rhinitis Patients, Healthy Controls
Neuro-immunological Analysis of Idiopathic Rhinitis Patients and Controls Treated With Capsaicin.
The term idiopathic rhinitis (IR) is used in this study to describe a patient group with following characteristics: patients with complaints of nasal obstruction, sneezing and/or rhinorrhea for a period of over 1 year, which…
- Trial name
- NCT01223820
- Testing
- Capsaicin
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven