Clinical trials: sponsored by Universitas Indonesia
Knee Surgery, Pelvic Surgery
ED50 of Dexmedetomidine as an Adjuvant to 0.5% Hyperbaric Bupivacaine 12.5 mg for Spinal Anesthesia in Hip and Knee Surgery: An Up-and-Down Method Approach
Determine ED50 dexmedetomidine adjuvant that can provide spinal anesthetic sensory blockade duration of 200 minutes on knee and pelvis surgery with up-and-down method.
- Conditions
- Knee Surgery, Pelvic Surgery, Spinal Aneshtesia
- Trial name
- NCT07144215
- Testing
- Dexmedetomidine 3 mcg, Dexmedetomidine 4 mcg, Dexmedetomidine 5 mcg
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Maternal Exposure, Health Behavior
Brain Probiotic and LC-PUFA Intervention for Optimum Early Life
Probiotics is suggested to play several roles in promoting health, including alleviating disease symptoms, protection against atopic disease, and modulating the immune system by improving the beneficial gut microbiota…
- Conditions
- Maternal Exposure, Health Behavior, Infant Development, Child Development
- Trial name
- BRAVE (NCT03851120)
- Testing
- Probiotics and LC-PUFA (480 mg DHA), Psychosocial stimulation and healthy eating education
- Where
- Indonesia
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Type 2 Diabetes Mellitus
Mesenchymal Stromal/Stem Cells-Derived Exosomes (MSC-Exos) Therapy for Type 2 Diabetes Mellitus Patients
This is an open-label randomized controlled trial with a pre-and-post-test control group design to evaluate the effect of Mesenchymal Stromal/Stem Cells-Derived Exosomes (MSC-Exos) as an adjunctive therapy on glycemic control and…
- Trial name
- NCT07144241
- Testing
- Mesenchymal Stromal/Stem Cells-Derived Exosomes (Exo-HWS + 1 vial Exo-HUVEC) Therapy, Mesenchymal Stromal/Stem Cells-Derived Exosomes (Exo-HWS ) Therapy
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Universitas Indonesia
Melasma
Secretome TGF Beta 3
A therapeutic modality currently being developed for melasma is secretome. Secretome is a bioactive molecule secreted by mesenchymal stem cells in a conditioned medium containing a large number of growth factors, cytokines…
- Trial name
- TGF Beta 3 (NCT07137130)
- Testing
- Concentrated secretome Injection 3 mL, Concentrated secretome Injection 3 mL with addition of TGF Beta 3
- Where
- Indonesia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Cleft Palate, Fistula of Soft Palate (Disorder)
LIMA Protocol Towards Palatal Fistula and Maxillary Growth in Cleft Palate
This randomized controlled trial compared palatoplasty outcomes using the LIMA protocol (Hybrid and one-flap techniques) versus the RSCM protocol (two-flap technique) in patients with unilateral Veau III-IV cleft palate at Cipto…
- Conditions
- Cleft Palate, Fistula of Soft Palate (Disorder), Maxillar Hypoplasia
- Trial name
- NCT07137169
- Testing
- LIMA protocol, RSCM Protocol
- Where
- Indonesia
- Volunteers
- 35 people
- Sponsor
- Universitas Indonesia
Craniotomy Surgery, Regional Anaesthesia
A Comparative Analysis of Combined Superficial Cervical Plexus and Supraorbital Blocks Compared to Scalp Blocks During Craniotomy: a Review of Opioid Consumption and The Suppression of Hemodynamic Responses
Perioperative pain management in craniotomy requires the administration of effective regional anesthetic techniques to reduce the use of systemic opioids and optimize hemodynamic control.
- Conditions
- Craniotomy Surgery, Regional Anaesthesia, Scalp Block, Plexus Block;Analgesia;Neurosurgery
- Trial name
- NCT07131046
- Testing
- Combination of superficial cervical plexus block and supraorbital block, Scalp block with bupivacaine alone
- Where
- Indonesia
- Volunteers
- 41 people
- Sponsor
- Universitas Indonesia
Lung Cancer Patients
Press Needle Acupuncture for Pain and Quality of Life in Lung Cancer Patients
The purpose of this clinical trial is to evaluate the effect of press needle acupuncture on pain management and quality of life improvement in patients with lung cancer.
- Trial name
- NCT07112950
- Testing
- Press Needle Acupuncture and standart therapy
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Post Craniotomy
Effect of Acupuncture on Hemodynamics and Pain of Post Craniotomy Patients With Mechanical Ventilation
The aim of this clinical trial is to prove that acupuncture therapy combined with standard therapy can optimize hemodynamics and reduce pain in post-craniotomy patients with mechanical ventilation.
- Trial name
- NCT06808256
- Testing
- the acupuncture therapy, Standard therapy
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Indonesia
Heart Defects, Congenital, Intensive Care Units, Pediatric
High-Flow Nasal Cannula vs. NIV After Extubation in Children Undergoing Heart Surgery
High-Flow Nasal Cannula vs. NIV After Extubation in Children Undergoing Heart Surgery
- Conditions
- Heart Defects, Congenital, Intensive Care Units, Pediatric, Respiration, Artificial, Extubation
- Trial name
- NCT07059689
- Testing
- High Flow Nasal Cannula (HFNC), Non-Invasive Ventilation (NIV)
- Where
- Indonesia
- Volunteers
- 114 people
- Sponsor
- Universitas Indonesia
Oropharyngeal Dysphagia, Swallowing Disorders
The Effect of Swallowing Exercise and Maneuver Program For Older Adults With Dysphagia in Nursing Home
This clinical trial aimed to evaluate the effectiveness of a structured swallowing exercise and maneuver program for older adults with dysphagia living in a nursing home.
- Conditions
- Oropharyngeal Dysphagia, Swallowing Disorders, Frailty-related Dysphagia, Nursing Homes
- Trial name
- NCT07049471
- Testing
- Swallowing Exercise and Maneuver Program for Older Adults with Dysphagia
- Where
- Indonesia
- Volunteers
- 72 people
- Sponsor
- Universitas Indonesia
Nasopharyngeal Cancinoma (NPC)
Impact of Vitamin D on Therapeutic Respons in NPC Chemoradiated Patients
Nasopharyngeal cancer is the sixth most common cancer and the sixth leading cause of death in Indonesia. NPC is a radiosensitive cancer so radiotherapy is the basic therapy for NPC.
- Trial name
- NCT07042711
- Testing
- Vitamin D 5,000IU Oral Tablet
- Where
- Indonesia
- Volunteers
- 300 people
- Sponsor
- Universitas Indonesia
Extubation Failure, Ventilated Patients
Factors Associated With Extubation Failure in Kanigara ICU (Intensive Care Unit) RSUPN Dr. Cipto Mangunkusumo
Extubation is the final stage after patients undergo weaning procedure from mechanical ventilation in the ICU. Extubation failure followed by reintubation is associated with worse patient outcomes, including prolonged length of…
- Trial name
- NCT07038291
- Testing
- Not applicable- observational study
- Where
- Indonesia
- Volunteers
- 156 people
- Sponsor
- Universitas Indonesia
Anterior Cruciate Ligament Rupture
Comparison of Clinical Outcomes Between All-Inside and Complete Tibial Tunnel Techniques in Anterior Cruciate Ligament Reconstruction Among Patients With ACL Ruptures
This study aims to compare the functional outcomes of patients with ACL rupture following ACL reconstruction surgery using hamstring grafts, between the all-inside technique and the complete tibial tunnel technique.
- Trial name
- NCT07023653
- Testing
- All-Inside Techniques, Complete Tibial Tunnel techniques
- Where
- 2 sites in Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia
Geriatric, General Anesthesia Induced Hypotension
What Causes Low Blood Pressure After Anesthesia in Older Adults Having Non-Heart Surgery ?
The purpose of this study is to identify risk factors contributing to post-induction hypotension in geriatric patients undergoing elective non-cardiac surgery under general anesthesia at Dr.
- Conditions
- Geriatric, General Anesthesia Induced Hypotension, Elective Surgery, Hypotension
- Trial name
- GERIHYPO (NCT07019805)
- Testing
- Standard General Anesthesia Induction Using Propofol, Fentanyl and Midazolam, Blood Pressure Continous Monitoring, syrnge pump for the anesthesia agent, and vasoconstrictor drug
- Where
- Indonesia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Neonatal Hypoglycemia
The Efficacy of Self-Manufactured 40% Dextrose Gel in Asymptomatic Transient Neonatal Hypoglycemia Treatment
The goal of this clinical trial is to determine the efficacy of 40% dextrose gel therapy as an additional therapy for the management of asymptomatic transient neonatal hypoglycemia in high risk infants The main question it aims…
- Trial name
- NCT07015450
- Testing
- self-manufactured 40% dextrose gel, Standard therapy
- Where
- 3 sites in Indonesia
- Volunteers
- 133 people
- Sponsor
- Universitas Indonesia
Acne Vulgaris
Efficacy, Safety Profile, and Post-Acne Sequelae of 0.025% Retinoic Acid Cream vs. 0.1% Adapalene Cream in Mild Acne Vulgaris in Fitzpatrick Skin Types III-V
The goal of this clinical trial is to compare the effectiveness, safety profile, and post-acne sequelae of 0.025% retinoic acid cream versus 0.1% adapalene cream for mild acne vulgaris in individuals with Fitzpatrick skin types…
- Trial name
- NCT07015931
- Testing
- retinoic acid cream 0.025%, adapalene cream 0.1%
- Where
- Indonesia
- Volunteers
- 23 people
- Sponsor
- Universitas Indonesia
Appetite Loss
Effectiveness of Cyproheptadine Hydrochloride Against Appetite to Improve Children's Nutritional Status
The goal of this clinical trial is to learn about the benefits of Cyproheptadine hydrochloride in increasing appetite as well as its effect on weight gain in children aged 1-5 years who have difficulty eating.
- Trial name
- NCT07006181
- Testing
- cyproheptadine hydrochloride
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Universitas Indonesia
Overweight
Comparing HICT and MICT for Health Improvements in Overweight Young Adults
The increasing prevalence of overweight and obesity is becoming a concern worldwide as it is associated with the increased prevalence of non-communicable diseases.
- Trial name
- HiMod Impact (NCT07008326)
- Testing
- High Intensity Circuit Training, Moderate Intensity Continuous Training
- Where
- Indonesia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Elective Surgical Procedure, ASA Physical Status I
Effectiveness of Intranasal Dexmedetomidine Premedication in Child Intubation
The purpose of this study is to find out if a medicine called dexmedetomidine, given as a nasal spray, can help patients stay calm and comfortable before having a breathing tube placed (intubation).
- Conditions
- Elective Surgical Procedure, ASA Physical Status I, ASA Physical Status II
- Trial name
- NCT06991647
- Testing
- Intranasal dexmedetomidine, 0.9% NaCl solution
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia
Sports Physical Therapy, Military Activity
The Effect Of Ears Acupuncture On Fitness Test 12 Minutes Running in Students Of Medical Faculty UNHAN RI
The goal of this clinical trial is to study the use of ear acupuncture in 12 minutes running test on third semester of cadets of Medical Faculty, Indonesia Defense University, between intervention and sham group.
- Conditions
- Sports Physical Therapy, Military Activity, Exercise Overtraining
- Trial name
- sportacup (NCT06708312)
- Testing
- press needle acupuncture
- Where
- Indonesia
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia