Clinical trials: sponsored by University Hospital, Montpellier
Knee Arthropathy, Hip Arthropathy
Patient Blood Management Program in Total Hip or Total Knee Arthroplasty
Total hip and knee arthroplasty are among the most common surgical procedures for which blood transfusion is prescribed. Patient blood management program has been proposed to decrease the need for transfusion.
- Trial name
- NCT04137484
- Where
- France
- Volunteers
- 723 people
- Sponsor
- University Hospital, Montpellier
Guided Bone
Bone Loss in Posterior Mandible Postextraction Sockets
The aim of this study is to evaluate the bone loss after extraction. The surgery protocol is flapless, and the teeth are mandibular premolars or molars leaving sockets with 4 walls intact or at least 3 walls intact and the buccal…
- Trial name
- NCT04051905
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Montpellier
Cystic Fibrosis
Educational Program Through Video Conference for Inhaled Therapies in Cystic Fibrosis Patients
Educational programs are essential for cystic fibrosis patients who need to take several different drugs every day. Compliance is often klow in these patients, and clinicals and paramedics try to increase it, through educational…
- Trial name
- Visio-Respir (NCT03850145)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Extracorporeal Life Support, Hypotension
Hypotension During Extracorporeal Circulatory Support Indicated for Cardiogenic Shock
The cardiogenic shock is characterized by an alteration of organs function following a decrease in cardiac output linked to an impairment of cardiac performance. The prognosis remains poor with mortality between 40 and 50%.
- Conditions
- Extracorporeal Life Support, Hypotension, Vasoplegia
- Trial name
- RetroECMO-VP (NCT03968926)
- Testing
- Arterial pressure management during circulatory support by VA-ECMO
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Post-Poliomyélitis Syndrom
Treatment of Post-poliomyelitis Syndrome by Intravenous Immunoglobulin
Our study evaluates the efficacy of IGIV treatment in PPS on clinical (walking and pain) and isokinetic (muscle strength) criteria, on patients with PS at Montpellier's Hospital
- Trial name
- PPS and IGIV (NCT04004390)
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Montpellier
BMI Greater Than 30
Establishment of a Database of Patients Suffering From Obesity With a Medical Treatment
Obesity is a public health problem, given its prevalence (15% in France in 2012, Obépi survey) but also by the complications that it generates. We were firstly, intersted in bone mineral density during obesity.
- Trial name
- Elodie Cohort (NCT03755323)
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Montpellier
Unexpected Delivery Outside Maternity
Observatory of Unintentional Births Hospital Extras
In France, pre-hospital unexpected birth is a rare situation, but over the last ten years, the investigators have seen an increase in the number of these.
- Trial name
- AIEH34 (NCT03820505)
- Where
- France
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Adverse Drug Event
Adverse Drug Events at Emergency Department
Emergency departments (EDs) are a crucial element of the health care systems at interface between hospital and communities. The goals of the ED are to make an initial diagnosis and deliver urgent and critical care 24 hour per day…
- Trial name
- ADEsED (NCT03442010)
- Testing
- Detection of adverse drug events
- Where
- France
- Volunteers
- 13,453 people
- Sponsor
- University Hospital, Montpellier
Drug Hypersensitivity
Drug Provocation Test (DPT) to Non Steroidal Anti-inflammatory Drugs (NSAID)
Background : Non steroidal anti-inflammatory drugs are responsible for 25% of reported adverse drug events which include immunological and non-immunological hypersensitivity reactions.
- Trial name
- NSAID (NCT03743220)
- Where
- France
- Volunteers
- 311 people
- Sponsor
- University Hospital, Montpellier
Critical Illness, ICU Acquired Weakness
Muscle Evaluation Using Ultrasound in the Critically Ill
Critical illness is associated with ICU acquired weakness and diaphragmatic dysfunction. Ultrasound can evaluate the muscle mass non invasively and provides the ability for a muscle follow up during and after the ICU stay.
- Trial name
- ULTRAMUSCLE (NCT03550222)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Tuberous Sclerosis Complex
Dermatologic Patterns of Tuberous Sclerosis Patients and Somatic Mutation Relationship
Tuberous Sclerosis is a rare genetic disorder that affects about one in 15,000 individuals. It is part of the phacomatoses: a germline mutation of the gene Tuberous Sclerosis Complex 1 (TSC1) or TSC2 causes a protein dysfunction…
- Trial name
- NCT04112537
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier
Optimal Treatment of Lymphedema
Surgery in Addition to the Medical Treatment of Lymphedema
Lymphedema is a chronic pathology with a real impact on the quality of life of patients. Despite optimal medical management of patients, some patients still have no pitting edema on which the medical treatment has no effect.
- Trial name
- LYMPHOSPIR (NCT03776214)
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Cardiac Surgery
sST2 and Cardiac Surgery
Evaluation of the prognosis value of sST2 dosed before cardiac surgery on prognosis of long terme prognosis after cardiac surgery.
- Trial name
- NCT03887767
- Where
- France
- Volunteers
- 158 people
- Sponsor
- University Hospital, Montpellier
Fall, Fatigue
Determinants of the Fall Risk Profile and Quality of Life of Older Subjects Visting Climatic Health Resorts
The main objective of the study conducted in subjects aged 65 or older visiting the French Balaruc-les-bains climatic health resort was to : Determine factors that distinguish fallers from not fallers Determine factors that may…
- Trial name
- NCT04277000
- Where
- France
- Volunteers
- 1,471 people
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder
Care Pathway for Children With Autism Spectrum Disorder Included in the ELENA Cohort
Autism Spectrum Disorder (ASD) is lifelong neurodevelopmental disorder that affect social communication and interaction and includes limited and repetitive patterns of behavior (DSM 5).
- Trial name
- ELENA-SNDS (NCT04292522)
- Where
- France
- Volunteers
- 903 people
- Sponsor
- University Hospital, Montpellier
Brachymetatarsia
One-stage Bone Lengthening in the Management of Brachymetatarsia
Brachymetatarsia is a shortening in length of a metatarsal exceeding 5mm. This congenital anomaly most often affecting women and the second metatarsal is associated with frequent aesthetic disorders leading patients to consult.
- Trial name
- BRACHYONESTAGE (NCT04287127)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Montpellier
Early Osteoarthritis
Clinical and Molecular Aspects of Early Osteoarthritis
The etiology of osteoarthritis is varied, ranging from multifactorial, environmental to monogenic. In individuals in whom osteoarthritis appears earlier than in the general population, it is called early osteoarthritis.
- Trial name
- NCT04267510
- Where
- France
- Volunteers
- 65 people
- Sponsor
- University Hospital, Montpellier
M.Abscessus Pulmonary Disease
Liposomal Amikacin Inhalation in M.Abscessus Patients
Mycobacterium abscessus is one of the many species of non-tuberculous mycobacteria. M. abscessus infections are known to be common in patients with cystic fibrosis (CF). Mycobacterium abscessus yields poor cure rates.
- Trial name
- NCT04163601
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Montpellier
Facioscapulohumeral Muscular Dystrophy
Effects Antioxidants Supplementation on Muscular Function Patients Facioscapulohumeral Dystrophy (FSHD)
On the basis of published data and the investigators' results indicating that oxidative stress may contribute to the peripheral skeletal muscle dysfunction in patients with FSHD, the investigators propose a study to test whether…
- Trial name
- FSHD (NCT01596803)
- Testing
- Taking of blood, needle biopsy of the vastus lateralis muscle, Vit C Vit E Zn Se
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Montpellier
Duchenne Muscular Distrophy (DMD)
Endomysial Fibrosis, Muscular Inflammatory Response and Calcium Homeostasis Dysfunction in Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is the most common and devastating form of muscular dystrophy, caused by an X-chromosome gene mutation resulting in the absence of the protein dystrophin.
- Trial name
- NCT01823783
- Testing
- Muscle biopsy
- Where
- 7 sites in France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
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