Clinical trials: sponsored by University of Aarhus
Type2 Diabetes
Novel Organic Kale Products for Prevention of Obesity/Type 2 Diabetes
Investigating the health beneficial effects of freeze-dried Brassica oleracea var. acephala with a high content of fibers, protein, vitamin, minerals, and secondary metabolites on patients with type 2 diabetes.
- Trial name
- NCT04298970
- Testing
- Intervention
- Where
- Denmark
- Volunteers
- 34 people
- Sponsor
- University of Aarhus
Osteopenia, Osteoporosis
Isoflavone Treatment for Postmenopausal Osteopenia.
The aim of the project is to execute a double-blind, parallel, randomized 12-month intervention trial on postmenopausal women with osteopenia (low bone mineral density), in order to determine the effects of daily intake of…
- Trial name
- NCT02174666
- Testing
- Red clover extract
- Where
- Denmark
- Volunteers
- 85 people
- Sponsor
- University of Aarhus
Prostate Cancer
The ProCaRis Study: Prostate Cancer Risk Assessment in General Practice
The preferred method for early detection of prostate cancer (PCa) in older men with family history is the Prostate Specific Antigen test (PSA test), although the method is imprecise.
- Trial name
- ProCaRis (NCT01739062)
- Testing
- Genetic risk assessment
- Where
- Denmark
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Alzheimer Disease
MRI Assessment of Impaired Glucose Metabolism in Alzheimer's Disease
Diseases of dementia are chronic, untreatable, and cause a massive burden of morbidity. In this proposal, we seek to tackle the problem of better, earlier, and more efficient diagnosis using deuterium metabolic imaging (DMI).
- Trial name
- NCT05402566
- Testing
- Deuterium metabolic imaging
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- University of Aarhus
Heart Failure
Hemodynamic Effects of Chronic Ketosis.
Heart Failure (HF) is a major public health issue because the disease affects 1-2% of the Western population and the lifetime risk of HF is 20%.
- Trial name
- KETO-CHF (NCT05161650)
- Testing
- Ketone monoester (3-OHB)
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- University of Aarhus
Heart Failure
Metabolic Effects of Chronic Ketosis (KETO-CHF Metabolic)
Heart Failure (HF) is a major public health issue because the disease affects 1-2% of the Western population and the lifetime risk of HF is 20%.
- Trial name
- NCT05161676
- Testing
- Ketone monoester
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Sex Chromosome Abnormality, Klinefelter Syndrome
Endocrine, Metabolic, Cardiovascular and Immunological Aspects of Sex Chromosome Abnormalities in Relation to Genotype
Observational study of 160 patients with sex-chromosome abnormalities and 160 matched controls. Blood, fat, muscle, skin, buccal swaps, urine will be collected and analyzed for DNA, RNA and methylation patterns.
- Conditions
- Sex Chromosome Abnormality, Klinefelter Syndrome, Turner Syndrome, Metabolic Disease
- Trial name
- EMKISCA (NCT05425953)
- Testing
- No intervention other than obtaining biopsies
- Where
- Denmark
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Mental Disorder
Validation of Instruments for Clinical Trial on Patients With Bipolar Disorder in Rwanda
This study evaluates the cultural and linguistic sensitivity and psychometric properties of a set of four adapted measurement instruments essential to determining the efficacy of group-psychoeducation for patients with bipolar…
- Trial name
- NCT04834999
- Testing
- Validation of questionnaires in Kinyarwanda
- Where
- Rwanda
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
X-linked Hypophosphatemia, Hereditary Hypophosphatemia
Characterising Pain, QoL, Body Composition, Arterial Stiffness, Muscles and Bones in Adult Persons With XLH and Healthy Controls
Hereditary hypophosphatemia (XLH) is a rare, inherited disease. Loss-of-function mutation in the phosphate regulating gene with homologies to endopeptidases on the X-chromosome (PHEX) results in excess fibroblast growth factor 23…
- Trial name
- NCT04273490
- Where
- Denmark
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Diabetes Mellitus, Type 2, Bone Fragile
Bone Turnover in Type 2 Diabetes and Non-diabetes Controls (DiaMarv)
Type 2 diabetes (T2D) is related to an increased risk of major fractures which does written in English. The summary is used not only increase society health care costs, but also increase the morbidity and in the recruitment of…
- Trial name
- DiaMarv (NCT05585697)
- Testing
- None - crossectional
- Where
- Denmark
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Rheumatoid Arthritis, Osteoporosis
Alendronate Treatment of Osteoporosis in Rheumatoid Arthritis
A randomized, double-blind, placebo-controlled trial including 160 consecutive patients who have been diagnosed with both rheumatoid arthritis (RA) and low bone mass and have been treated with alendronate (ALN) for five years or…
- Trial name
- ALOSTRA (NCT02944799)
- Testing
- Alendronate, Calcium, Vitamin D
- Where
- 6 sites in Denmark
- Volunteers
- 69 people
- Sponsor
- University of Aarhus
Osteoarthritis
The Effect of Implant Coating (BoneMaster) on Migration and Clinical Outcome in Hip Arthroplasty With the Exceed Cup
This study focuses on the effect of the hydroxyapatite coating with BoneMaster on the fixation of the hip prosthesis in primary hip alloplasty.
- Trial name
- NCT02311179
- Testing
- Prosthesis, BoneMaster-Exceed cup (Biomet), Prosthesis Exceed cup without HA (Biomet)
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- University of Aarhus
Osteoarthritis, Knee
Oxford Partial Knee Replacement. A Randomized Clinical Trial of Three Implant Types
The purpose of this scientific study is to clarify whether there is a relationship between the appearance of radiolucent lines in bone-cement interphase of the tibial component of the different models of the Oxford Uni Knee…
- Trial name
- NCT00679120
- Testing
- Oxford Uni Knee
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- University of Aarhus
Renal Cancer
KIDNEY-PAGER: Analysis of Circulating Tumor DNA as a Biomarker in Renal Cancer - an Observational Trial
The overall aim of this observational study is to confirm that circulating tumor DNA (ctDNA) detected in plasma and or urine after intended curative treatment for renal cell carcinoma (RCC) can be applied in clinical practice as…
- Trial name
- KIDNEY-PAGER (NCT06145139)
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- University of Aarhus
Glucocorticoids Toxicity, Iatrogenic Effect
Effects of Glucocortioids in Human Skeletal Muscle, Adipose Tissue and Skin
BACKGROUND: A notorious and dreaded adverse effect of glucocorticoids (GC) is redistribution of muscle and fat mass towards muscle wasting and visceral obesity.
- Trial name
- FUSION (NCT06145126)
- Testing
- Prednisolone
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Uterine Cervical Cancer, Uterine Cervix Cancer
Three Birds With One Stone
The overall aim of the study is to increase participation rates in cervical cancer (CCU) and colorectal cancer (CRC) screening programmes in Denmark by offering home-based CCU and CRC screening to women who are overdue for one or…
- Conditions
- Uterine Cervical Cancer, Uterine Cervix Cancer, Uterine Cervical Neoplasm, Colorectal Neoplasms
- Trial name
- NCT05022511
- Testing
- Screening status
- Where
- Denmark
- Volunteers
- 27,099 people
- Sponsor
- University of Aarhus
Primary Angle Glaucoma Closure Suspect
Danish Angle Closure Prevention Trial
To determine whether primary angle closure suspects (PACS) in a Caucasian population benefit from prophylactic laser iridotomy.
- Trial name
- DAP (NCT06077253)
- Testing
- Iridotomy
- Where
- 5 sites in Denmark
- Volunteers
- 242 people
- Sponsor
- University of Aarhus
Commotio Cerebri, Mild Traumatic Brain Injury
Get Going After concussioN 2.0
The study tests the promising results of a previous study (GAIN 1.0) in a larger RCT (GAIN 2.0) which takes place in the municipalities of Central Denmark Region where citizens live their daily lives and whose health- and social…
- Trial name
- GAIN2 (NCT04798885)
- Testing
- GAIN 2.0
- Where
- Denmark
- Volunteers
- 310 people
- Sponsor
- University of Aarhus
Faecal Incontinence, Fecal Incontinence
Sacral Nerve Stimulation for Faecal Incontinence - Placebo or Clinical Effective
Sacral nerve stimulation (SNS) has over the last 20 years been recognised as an efficient treatment option for faecal incontinence (FI).
- Trial name
- SNS (NCT03261622)
- Testing
- Sacral nerve stimulation at different stimulation amplitudes
- Where
- Denmark
- Volunteers
- 73 people
- Sponsor
- University of Aarhus
Post-transplant Lymphoproliferative Disorder, Mononucleosis
Early Detection of Epstein-Barr Virus Related Disease.
Epstein-Barr virus (EBV) is one of several herpesviruses that cause disease in humans. EBV virus has an oncogenic potential, and it has been associated with the development of a wide range of cancers.
- Conditions
- Post-transplant Lymphoproliferative Disorder, Mononucleosis, Epstein-Barr Virus Infections, Epstein-Barr Virus Related Malignancy
- Trial name
- NCT03546101
- Where
- Denmark
- Volunteers
- 1,527 people
- Sponsor
- University of Aarhus
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