Clinical trials: sponsored by University of Aarhus
Pediatric Obesity
Factors Associated With Changes in Weight-status in Danish School Children With Obesity
Childhood obesity is increasing worldwide and causes a major health concern. Only limited insight exists into the natural history of childhood obesity at children already classified as obese.
- Trial name
- NCT06077266
- Testing
- Change of weight class to normal weight
- Where
- Denmark
- Volunteers
- 467 people
- Sponsor
- University of Aarhus
Diabetes Mellitus, Type 2, Randomized Controlled Trial
LIVING - Physical Activity in a Self-management Program Among Persons With Type 2 Diabetes
The goal of this pragmatic clinical trial is to evaluate two municipality-based interventions, Lev Livet (one without physical activity and one with) against no intervention in people with type 2 diabetes.
- Trial name
- NCT06091501
- Testing
- Lev Livet
- Where
- Denmark
- Volunteers
- 288 people
- Sponsor
- University of Aarhus
Chronic Postsurgical Pain, Acute Post Operative Pain
Prediction of Chronic Postsurgical Pain in Adults
This research will be a prospective single-centre observational cohort study in Denmark spanning approximately one year. The objective of this study is to develop a clinically applicable and generalizable prediction model for…
- Trial name
- NCT04866147
- Testing
- Cardiothoracic surgery, Breast surgery, Gastrointestinal surgery
- Where
- 2 sites in Denmark
- Volunteers
- 1,522 people
- Sponsor
- University of Aarhus
Anxiety Disorders
Development, Feasibility and Acceptability of an iCBT Intervention for Adolescents With Anxiety
The aim of the feasibility study is twofold: 1) to test the feasibility of the study design, and 2) to test the preliminary efficacy and the acceptability of a new iCBT intervention when delivered with different levels of…
- Trial name
- NCT06076954
- Testing
- CoolMinds
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Heart Failure With Preserved Ejection Fraction, Diabetes Mellitus, Type 2
Modulation of Circulating Levels of the Ketone Body 3-hydroxybutyrate in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction: Metabolic Effects. (KETO-HFpEF-Metabolic)
Heart failure (HF) is among the most common causes of death in patients with type 2 diabetes (T2D). Ketones, 3-hydroxybutyrate (3-OHB), have shown to have beneficial effects in patients with hearth failure with reduced ejection…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Diabetes Mellitus, Type 2, Ketonemia
- Trial name
- NCT05159570
- Testing
- Ketone ester
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Heart Failure With Preserved Ejection Fraction, Diabetes Mellitus, Type 2
Modulation of Circulating Levels of the Ketone Body 3-hydroxybutyrate in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction: Cardiovascular Effects.
Heart failure (HF) is among the most common causes of death in patients with type 2 diabetes (T2D). Ketones, 3-hydroxybutyrate (3-OHB), have shown to have beneficial hemodynamics effect in patients with hearth failure with…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Diabetes Mellitus, Type 2, Ketonemia
- Trial name
- KETO-HFpEF (NCT05236335)
- Testing
- Ketone ester
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- University of Aarhus
Acute Pain, Opioid Use
Low-dose KETamine as an Adjunct to MOrphine for Acute Pain in the ED
The KetMo study is an investigator-initiated, randomized, parallel group, double blinded trial investigating if ketamine as an adjunct to morphine improves pain treatment in the ED.
- Trial name
- KetMo (NCT05422001)
- Testing
- low dose ketamine
- Where
- Denmark
- Volunteers
- 116 people
- Sponsor
- University of Aarhus
Readmission
Prevalence of Factors Contributing to Unplanned Hospital Readmission of Older Medical Patients
We need to identify the essential factors that are linked to readmission among older medical patients as approximately 20% of all medical patients above the age of 65 are readmitted within 30 days after discharge.
- Trial name
- NCT05116644
- Testing
- NONE - this is a cross-sectional survey design
- Where
- Denmark
- Volunteers
- 165 people
- Sponsor
- University of Aarhus
Insomnia Chronic
Determination of Optimal Sleep Treatment Elements - Pilot
Previous research has shown the efficacy of (combinations of) individual components of cognitive behavioral therapy for insomnia (CBT-I), namely sleep hygiene education, sleep optimization, stimulus control therapy…
- Trial name
- DOSE (NCT05561790)
- Testing
- eCBT-I
- Where
- Denmark
- Volunteers
- 169 people
- Sponsor
- University of Aarhus
Chronic Kidney Diseases
The Danish Symptomburden Study Among Patients With Advanced Kidney Disease
Patients with chronic kidney disease stage five have a high symptom burden regardless of whether they are treated with dialysis or without dialysis, a conservative kidney management pathway (CKM).
- Trial name
- NCT06019871
- Testing
- Dialysis
- Where
- Denmark
- Volunteers
- 341 people
- Sponsor
- University of Aarhus
Pain, Postoperative, Postoperative Complications
Methadone in Cystectomy Patients
The role of a single-dose intraoperative methadone on postoperative pain and opioid consumption in patients undergoing Surgeon Accuracy Robot Assistant cystectomy.
- Conditions
- Pain, Postoperative, Postoperative Complications, Pathologic Processes, Bladder Cancer
- Trial name
- METAMORF (NCT04475029)
- Testing
- Methadone, Morphine
- Where
- Denmark
- Volunteers
- 114 people
- Sponsor
- University of Aarhus
Tuberculosis, Tuberculosis, Pulmonary
Treating Tuberculosis Wasting With a High-protein Supplement
Undernutrition at the time of diagnosis of active tuberculosis is a risk factor for increased mortality, and lack of weight gain during anti-tuberculous treatment has been linked to an increased relapse risk.
- Conditions
- Tuberculosis, Tuberculosis, Pulmonary, Undernutrition, Malnutrition
- Trial name
- NUTRIATO (NCT03302949)
- Testing
- Lacprodan® DI-8090
- Where
- Guinea-Bissau
- Volunteers
- 232 people
- Sponsor
- University of Aarhus
Multiple Sclerosis
Physical and Cognitive Performance During the Two First Years of Lemtrada Treatment
Multiple Sclerosis (MS) is a chronic autoimmune neurodegenerative disease of the central nervous system (CNS). The symptoms of MS are wide-ranging, but patients perceive loss of physical function (gait) and cognitive function as…
- Trial name
- NCT03806387
- Testing
- Alemtuzumab
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- University of Aarhus
Multiple Sclerosis
"Outwalk MS" - Benefits of Outdoor Walking in Multiple Sclerosis
Deterioration of walking capacity is a common symptom in persons with multiple sclerosis (pwMS), furthermore having a negative influence on well-being.
- Trial name
- NCT05415956
- Testing
- Walking exercise therapy
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Frail Elderly, Clostridioides Difficile
Clostridioides Difficile and Frailty
CDI is a major cause of antibiotics-associated diarrhoea. More than half of the patients affected are 70 years or older and frail. Mortality among older patients with CDI is high.
- Conditions
- Frail Elderly, Clostridioides Difficile, Geriatric Assessment, Faecal Microbiota Transplantation
- Trial name
- CLODIFRAIL (NCT05447533)
- Testing
- Comprehensive geriatric assessment (CGA), Continued geriatric care, Faecal microbiota transplantation (FMT)
- Where
- Denmark
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pain, Parkinson Disease
Experimental Pain in Parkinsons
Study comparing pain intensity and discomfort in patients with Parkinson´s disease and healthy controls during inducement of mechanical, thermal, and chemical experimental pain
- Trial name
- ExPainPD (NCT05981261)
- Testing
- inducement of experimental pain
- Where
- Denmark
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pre-Term, Cervical Insufficiency
Obstetric Outcome in Pregnancies Treated With Laparoscopic Cerclage
Preterm birth is a leading cause of neonatal mortality and morbidity. Cervical insufficiency is one factor implicated in the complex mechanisms involved in spontaneous preterm birth.
- Trial name
- NCT05863481
- Testing
- Laparoscopic cerclage placement
- Volunteers
- 185 people
- Sponsor
- University of Aarhus
Enuresis, Nocturnal
The Effect of Selecting Treatment With Desmopressin or Alarm to Children With Enuresis Based on Home Recordings.
The aim of this study is to investigate the importance of clinical characterization of children with monosymptomatic nocturnal enuresis (MNE) in order to improve treatment efficacy.
- Trial name
- DRYCHILD (NCT03389412)
- Testing
- Desmopressin, Conditional alarm
- Where
- 6 sites in Belgium, China and 2 more
- Volunteers
- 324 people
- Sponsor
- University of Aarhus
Nocturnal Enuresis
Biomarkers in Urine for Children With Monosymptomatic Nocturnal Enuresis and Nocturnal Polyuria
The aim of the study is to identify protein markers in relation to the enuresis related nocturnal polyuria by using mass spectrometry on nocturnal urine samples.
- Trial name
- NCT04049019
- Testing
- Urine collection through a collecting device (Uridome®) for maximum 1 week, Urine collection
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Anxiety, Autism
Testing a CBT Program for Anxiety in Teenagers With Autism: A Feasibility Study
The objective is to investigate the feasibility of a newly developed manualised group Cognitive Behavioural Therapy (CBT) programme for anxiety in 15 teenagers (aged 13-17 years) with Autism Spectrum Disorder (ASD).
- Trial name
- NCT04838912
- Testing
- Cool Kids (Chilled) Anxiety program adapted to children and youths with autism and anxiety disorders.
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
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