Clinical trials: sponsored by University of Aarhus
Knee Arthroplasty
Rehabilitation After Fast-track Total Knee Arthroplasty
BACKGROUND In 2008 approximately 7,700 total knee arthroplasties (TKA) were performed in Denmark. The results after TKA is in general very good, the investigators have, however, discovered that patients following fast-track TKA…
- Trial name
- HOLEST (NCT01329081)
- Testing
- Postoperative rehabilitation after fast-track TKA
- Where
- Denmark
- Sponsor
- University of Aarhus
Osteoarthritis
A Comparison of Fixation Method in Total Knee Arthroplasty - Low Viscosity Versus High Viscosity Bone Cement
The purpose of this study is to compare the early migration and periprosthetic bone changes of two total knee arthroplasties fixated with two different type bone cement.
- Trial name
- NCT00175162
- Testing
- Osteopal G vs. Refobacin-Palacos R bone cement
- Where
- Denmark
- Sponsor
- University of Aarhus
Osteoarthritis
A Roentgen Stereophotogrammetric Analysis on Migration of Knee Prostheses.
The purpose of this study is to compare the early migration of two uncemented total knee arthroplasties with different metal coating. Only the tibial prosthesis plateau varies.
- Trial name
- Ti-Tan (NCT00138853)
- Testing
- Tibial component
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Osteonecrosis, Femoral Neck Fracture
A Comparison of Two Different Surgical Techniques in Hip Resurfacing Arthroplasty
The purpose of the study is to compare two different surgical techniques in hip resurfacing arthroplasty (RHA), comparing bloodflow and metabolism in the femoral head, as well as implant migration, periprosthetic bone mineral…
- Conditions
- Osteonecrosis, Femoral Neck Fracture, Implant Failure
- Trial name
- NCT00913679
- Testing
- Surgical approach (ReCap Hip Resurfacing System)
- Where
- Denmark
- Volunteers
- 49 people
- Sponsor
- University of Aarhus
Stroke
TReatment Strategy In Acute Ischemic larGE Vessel STROKE: Prioritize Thrombolysis or Endovascular Treatment
Should we prioritize thrombectomy or thrombolysis in acute stroke? Finding the answer to this question will improve treatment and outcome for stroke patients only by changing triage and transportation.
- Trial name
- TRIAGE (NCT03542188)
- Testing
- Primary Stroke Center (PSC), Comprehensive Stroke Center (CSC)
- Where
- Denmark
- Volunteers
- 174 people
- Sponsor
- University of Aarhus
Spinal Cord Injuries, Spinal Cord Diseases
Impact of Peripheral Afferent Input on Central Neuropathic Pain
The overarching aim of this study is to investigate the contribution of peripheral afferent input to spontaneous and evoked central neuropathic pain after a spinal cord lesion or disease.
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Syringomyelia
- Trial name
- NCT05646810
- Testing
- Lidocaine (10 mg/ml), Isotonic saline
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Hip Dislocation
Investigation of Efficacy of Use of a Bandage
This trial investigates the effectiveness of using a bandage after dislocation of the hip after total hip arthroplasty. Patients with a dislocated hip after total hip arthroplasty coming to the emergency department to have the…
- Trial name
- NCT05012969
- Testing
- Hipstop bandage
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Fibromyalgia, Irritable Bowel Syndrome
Welfare Benefits in Functional Somatic Disorders
The objective of this observational study is to estimate the number of weeks of welfare benefits, i.e. sickness benefit, unemployment benefit and social assistance, for individuals with functional somatic disorders and compare…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Chronic Fatigue Syndrome, Bodily Distress Syndrome
- Trial name
- NCT05611606
- Volunteers
- 9,656 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Irritable Bowel Syndrome, Fibromyalgia
Psychological Risk Factors for Functional Somatic Disorders
The objective of this study is to explore the role of neuroticism, perceived stress, and adverse life events, respectively, in the development and perpetuation of functional somatic disorders.
- Conditions
- Irritable Bowel Syndrome, Fibromyalgia, Chronic Fatigue Syndrome, Somatoform Disorders
- Trial name
- NCT05631860
- Volunteers
- 7,493 people
- Sponsor
- University of Aarhus
Stress, Psychological, Mental Health Issue
Engaged and Resilient - a Preventive Intervention to Promote Psychological Well-being and Mental Health for Leaders
Leaders in organizations must handle organizational complexity and adversity as part of their position and profession. Work-related risk exposure is associated with perceived stress, low engagement, and mental health issues.
- Trial name
- NCT04727255
- Testing
- Engaged and Resilient intervention
- Where
- Denmark
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Diabetes Mellitus, Type 2, Gestational Diabetes
Hormonal and Inflammatory Changes During Pregnancy in Women With Glucose Metabolic Disorders.
The first aim of this study is to describe maternal hormonal and inflammatory changes during pregnancy in women that differ metabolically (limited to women with type 2 diabetes, gestational diabetes and/or overweight).
- Conditions
- Diabetes Mellitus, Type 2, Gestational Diabetes, Overweight and Obesity, Pregnancy in Diabetic
- Trial name
- HI-MET (NCT04617405)
- Testing
- No interventions
- Where
- 3 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- University of Aarhus
Diabetes Mellitus, Type 2, Gestational Diabetes
Mechanisms Behind Severe Insulin Resistance During Pregnancy in Women With Glucose Metabolic Disorders (SIR-MET)
The aim of this study is to describe the metabolic changes during pregnancy in women with type 2 diabetes or gestational diabetes in order to detect the pathophysiological mechanisms behind severe insulin resistance during…
- Conditions
- Diabetes Mellitus, Type 2, Gestational Diabetes, Overweight and Obesity, Pregnancy in Diabetic
- Trial name
- NCT04924504
- Testing
- No interventions
- Where
- 2 sites in Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
In-hospital Diabetes Management With Flash Glucose Monitoring (isCGM) - the INDIGO Study, Part A
The aim of the study is to investigate the applicability of a Flash glucose monitoring sensor (Freestyle Libre, isCGM) for in-hospital glucose monitoring in patients with diabetes requiring nutritional therapy (tube feeding or…
- Conditions
- Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus
- Trial name
- NCT04650945
- Testing
- isCGM group
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- University of Aarhus
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
In-hospital Diabetes Management With Flash Glucose Monitoring (isCGM) - the INDIGO Study, Part B
The aim of the study is to investigate the applicability of a Flash glucose monitoring sensor (Freestyle Libre, isCGM) for in-hospital glucose monitoring in patients with diabetes and hypoglycemia (<3,9 mmol/l) during the…
- Conditions
- Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus
- Trial name
- INDIGO (NCT04630925)
- Testing
- isCGM
- Where
- Denmark
- Volunteers
- 1 people
- Sponsor
- University of Aarhus
Overweight and Obesity, Overweight Adolescents
Breakfast for Young Females
Investigators will test the health effects of eating a dairy-based protein-rich breakfast or isocaloric breakfast and performing regular physical exercise training for 12 weeks in young overweight women (2 x 2 factorial design).
- Conditions
- Overweight and Obesity, Overweight Adolescents, Metabolic Disease
- Trial name
- NyStart2 (NCT04518605)
- Testing
- Low protein breakfast, High protein breakfast, Exercise training
- Where
- Denmark
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Growth, Vitamin D Supplementation
Next-generation Effects of Vitamin D Supplementation in Pregnancy
Vitamin D deficiency is common among pregnant women, despite daily vitamin D supplements. This study aims to investigate if maternal vitamin D intake of 90 vs 10 µg affects the overall health, growth, and immune system of the…
- Conditions
- Growth, Vitamin D Supplementation, Immune System Diseases, Child Development
- Trial name
- NCT05616117
- Testing
- Intrauterine 90µg D-vitamin, Intrauterine 10µg D-vitamin
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Stroke
Brain Computer Interface Training After Stroke
In this study, we want to examine the effect of a new treatment approach for patients with severe upper limb paresis in the subacute phase after stroke.
- Trial name
- NCT04071587
- Testing
- Brain Computer Interface training, Control
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis
Glucagon Resistance in Patients With NAFLD
The investigators propose that the sensitivity to glucagon in hepatic lipid metabolism is impaired in subjects with non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH).
- Conditions
- Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis, Glucose Metabolism Disorders
- Trial name
- NCT04042142
- Testing
- glucagon
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pregnancy Related, Sleep Disturbance
Treating Pregnancy Related Insomnia With Music
This study aims to examine the effects of 4 weeks music listening at bedtime on sleep quality during the third trimester of pregnancy.
- Conditions
- Pregnancy Related, Sleep Disturbance, Insomnia
- Trial name
- NCT04633395
- Testing
- Music, Sleep hygiene
- Where
- Denmark
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Orthodontic Appliances, Fixed
Computer-aided Indirect Bonding Versus Traditional Direct Bonding of Brackets in Orthodontic Patients
Accurate bracket positioning is one of the keys for effective orthodontic treatment. Traditionally, orthodontic brackets are positioned one-by-one on the teeth of the patient, with the so-called direct bonding method.
- Trial name
- NCT04395625
- Testing
- Direct bonding of Orthodontic brackets, Indirect bonding of Orthodontic brackets
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
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