Clinical trials: sponsored by University of Aarhus
Anal Cancer, Recurrent Anal Cancer
Pencil Beam Proton Therapy for Recurrences in Anal Cancer Patients Previously Treated With Radiotherapy (DACG 5)
This protocol aims to determine toxicity and efficacy of re-irradiation for patients with recurrences from anal cancers with dose-escalated pencil beam proton therapy either pre-operative for marginally resectable recurrences or…
- Trial name
- ReRad III (NCT05055635)
- Testing
- Pencil beam proton therapy
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- University of Aarhus
Glioblastoma
TMS Electrochemotherapy for Glioblastoma Multiforme
The proposed project aims to develop novel electrochemotherapeutic treatment of glioblastoma multiforme (GBM). Standard treatment has limited effect on survival and quality of life.
- Trial name
- NCT02283944
- Testing
- TMS
- Sponsor
- University of Aarhus
Neuralgia
Towards Individualized Deep Brain Stimulation Treatment of Chronic Neuropathic Pain
Chronic neuropathic pain affects millions of individuals worldwide. It causes marked reduction of health, utility and quality of life and represents a considerable economic burden to society due to loss of work capacity and large…
- Trial name
- DBSforPain (NCT01899170)
- Testing
- Deep brain stimulation, Cervel Neurotech, Multi-coil TMS, 11C-Carfentanil
- Where
- Denmark
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Colon Adenocarcinoma, Diarrhea
The Pathogenesis of Chronic Diarrhoea After Treatment for Cancer in Cecum and the Ascending Colon
Many patients suffer from chronic diarrhoea after surgical treatment for cancer in the right side of the colon. The investigators' main hypothesis is that colon cancer patients with chronic diarrhoea have a higher risk of bile…
- Trial name
- NCT04003181
- Testing
- Antibiotics, Bile Acid Binder
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- University of Aarhus
Precursor Cell Lymphoblastic Leukemia-Lymphoma, Recurrence
Childhood Acute Lymphoblastic Leukaemia: Follow-Up
Over the past decades, advances in treatment have led to an increasing number of children who survive cancer, resulting in a growing population of childhood cancer survivors.
- Trial name
- NCT03545659
- Testing
- Mode of relapse/SMN detection
- Where
- 5 sites in Denmark, Finland and 3 more
- Volunteers
- 277 people
- Sponsor
- University of Aarhus
Metabolic Disease, Insulin Sensitivity
Metabolic Effects of Melatonin Treatment
Modern living is associated with an epidemic of type 2 diabetes mellitus (T2DM). Sleep disturbances such as insomnia or frequent awakenings are strong risk factors for T2DM with several studies indicating a central role of…
- Conditions
- Metabolic Disease, Insulin Sensitivity, Glucose Metabolism Disorders (Including Diabetes Mellitus), Type 2 Diabetes Mellitus
- Trial name
- NCT03859934
- Testing
- Melatonin
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- University of Aarhus
Idiopathic Pulmonary Fibrosis
Immunopathologic Profiles and Blood Biomarkers in Patients With IPF
Examination of expression of PD-L1, PD-L2, Beta- catenin, B-cell follicles and Tenascin- C in patients with IPF compared with other interstitial lung diseases.
- Trial name
- NCT04187079
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Hypovolemia, Fluid Overload
Prediction of the Effect of Fluid Administration Using Arterial Pressure and Ventilator Data During Abdominal Surgery
It is well known, that patients with circulatory impairment sometimes, but not always, benefit from intravenous fluids. Predicting if a fluid administration will improve circulation is therefore of substantial clinical interest.
- Trial name
- NCT04298931
- Testing
- Series of ventilator settings
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- University of Aarhus
Diabetes Mellitus, Type 2, Obesity
Effect of Roux-en-Y Gastric Bypass or Gastric Sleeve Surgery on Type 2 Diabetes
Roux-en-Y Gastric Bypass surgery (RYGB) ameliorates type 2 diabetes within days after surgery. Studies indicate that the gastric sleeve procedure has comparable effect on type 2 diabetes, but to what extent and how is not fully…
- Trial name
- NCT02713555
- Testing
- Roux-en-Y Gastric Bypass, Gastric Sleeve
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Shoes
Footwear Among Medical Doctors
The footwear fashion among medical doctors has been static for decades with a high preference for clogs. However, other types of shoes have been introduced, including sneakers, sandals etc.
- Trial name
- TÅFIS (NCT04740281)
- Testing
- Footwear
- Where
- Denmark
- Volunteers
- 154 people
- Sponsor
- University of Aarhus
Osteogenesis Imperfecta
The Effect of Treatment With Teriparatide and Zoledronic Acid in Patients With Osteogenesis Imperfecta
Osteogenesis imperfecta (OI) is an inherited disease of the connective tissue. Symptoms are fractures, growth retardation, blue sclera, bad teeth, impaired hearing a.o.
- Trial name
- NCT01679080
- Testing
- Zoledronic acid, Teriparatide, No active treatment
- Where
- 3 sites in Denmark
- Volunteers
- 9 people
- Sponsor
- University of Aarhus
Infertility
Involuntary Childlessness and Stress Management
Many couples experience involuntary childlessness and seek treatment at fertility clinics. Going through treatment procedures can be very challenging, time consuming and emotionally demanding.
- Trial name
- NCT01187095
- Testing
- Expressive writing, Active ctrl
- Where
- Denmark
- Volunteers
- 298 people
- Sponsor
- University of Aarhus
Functional Disorder
Feasibility and Pilot Testing of Group-based ACT for Adolescents With Functional Somatic Syndromes
Recurrent and impairing functional somatic syndromes (FSS) are common in adolescents. Despite a high need for care, empirically supported treatments are lacking for youth.
- Trial name
- AHEAD (NCT04464447)
- Testing
- Acceptance and Commitment Therapy
- Volunteers
- 21 people
- Sponsor
- University of Aarhus
Multiple Sclerosis, Brain Atrophy
Aerobic Exercise and Brain Health in Multiple Sclerosis
The purpose of the project is to investigate how aerobic exercise affects brain volume, specific brain regions, neurotrophins and cognition in patients with multiple sclerosis.
- Conditions
- Multiple Sclerosis, Brain Atrophy, Cognitive Impairment
- Trial name
- NCT02661555
- Testing
- Aerobic exercise
- Where
- Denmark
- Volunteers
- 86 people
- Sponsor
- University of Aarhus
Allergy, Immune Tolerance
Effect of Intralymphatic Immunotherapy
The investigators want to investigate whether specific immunotherapy can be delivered directly into a lymph node. The investigators think that a direct introduction of allergen to the antigen presenting cells in the lymph node a…
- Conditions
- Allergy, Immune Tolerance, Injection Site Discomfort
- Trial name
- NCT02255604
- Testing
- Alk (225) Phleum Pratense. 0.1 ml of 10,000 standard quantity units/ml., 0.1 ml Isoton saline
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- University of Aarhus
Neuralgia, Spinal Cord Stimulation
Examining Carryover Effect in Patients Treated witH Spinal cOrd Stimulation (ECHO)
Spinal cord stimulation is a minimally invasive surgical treatment for severe, chronic, neuropathic pain that is refractory to conventional treatment.
- Trial name
- ECHO (NCT03386058)
- Testing
- Temporary device deactivation
- Where
- 10 sites in Belgium, Canada and 4 more
- Volunteers
- 200 people
- Sponsor
- University of Aarhus
Heart Defects, Congenital
Impact of Congenital Heart Disease on Neurodevelopmental Outcome
The project aims toward clarifying the underlying mechanism and the long-term impact of congenital heart disease on neurodevelopment.
- Trial name
- NCT03871881
- Testing
- Magnetic Resonance Imaging, Neuropsychological assessment
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Non-small Cell Lung Cancer
The Utility of PET/CT in the Planning of Stereotactic Body Radiotherapy for Non-small Cell Lung Cancer
The trial evaluates the utility of 18FDG-PET/CT scan in the target definition process when SBRT is planned for stage I NSCLC.
- Trial name
- NCT00380666
- Testing
- PET/CT scan
- Sponsor
- University of Aarhus
Adverse Effects for Adaptive RT of Bladder Cancer
Adaptive Radiotherapy Using Plan Selection for Bladder Cancer
This protocol describes a Phase 2 clinical trial of online adaptive Radiotherapy, using a library of 3 dose plans corresponding to Small, Medium and Large size bladder.
- Trial name
- plan selection (NCT01762527)
- Testing
- Adaptive Radiotherapy
- Where
- 3 sites in Denmark
- Volunteers
- 65 people
- Sponsor
- University of Aarhus
Atrial Septal Defect, Pulmonary Hypertension
Atrial Septal Defect - Exercise Capacity and Pulmonary Hypertension
The purpose of the study is to compare exercise capacity, cardiac contractility, pulmonary vascular pressures and heart rate variability between patients with an atrial septal defect and healthy controls.
- Trial name
- NCT03565471
- Testing
- Echocardiography, Right side catheterization, Exercise test
- Where
- Denmark
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
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