Clinical trials: sponsored by University of Alberta
Overbite (Excessive) Horizontal
Study the Effect of Upper Expansion Appliances on Lower Jaw Forward Projection/Growth
Young children with backward positioned lower jaw/chin will be recruited to have an upper jaw expansion appliance. Previous research showed that the use of similar appliances can lead to lower jaw forward growth.
- Trial name
- NCT03286569
- Testing
- Upper arch Wilson quadhelex appliance
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Living Donor Kidney Transplantation
Multidisciplinary Support to Access Living Donor Kidney Transplant (MuST AKT)
For people living with kidney failure, the two active treatment options are dialysis or kidney transplantation. Transplantation is optimal, and especially from a living donor - offering patients longer survival, a better quality…
- Trial name
- MuST AKT (NCT05459337)
- Testing
- MuST AKT
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- University of Alberta
Cardiovascular Risk Factors, Blood Pressure
Pharmacist Case Finding and Intervention for Vascular Prevention Trial
Heart disease is a common and serious medical condition which causes nearly one in every three deaths worldwide every year. The factors which increase people's risk for heart disease are well-known, but there needs to be more…
- Conditions
- Cardiovascular Risk Factors, Blood Pressure, Cardiovascular Disease, Diabetes
- Trial name
- PRxOACT (NCT06405880)
- Testing
- Pharmacist-led care pathway
- Where
- Canada
- Volunteers
- 1,003 people
- Sponsor
- University of Alberta
Tracheostomy
Digital Health Pathway for Children With Medical Complexity Requiring Tracheostomy
The DECIDE-T project is developing a standardized clinical pathway specifically for pediatric patients who require tracheostomy with or without long-term ventilation (tracheostomy/LTV).
- Trial name
- DECIDE-T (NCT06375369)
- Testing
- Digital health pathway for children with medical complexity requiring tracheostomy (DECIDE-T)
- Where
- 2 sites in Canada
- Volunteers
- 180 people
- Sponsor
- University of Alberta
PCOS, Cardiovascular Disease
Fish Oil, Metformin and Heart Health in PCOS
Women with Polycystic Ovary Syndrome (PCOS) have high testosterone levels which is associated with altered insulin-glucose metabolism and an adverse blood lipid profile, predisposing them to the development of Type II Diabetes…
- Conditions
- PCOS, Cardiovascular Disease, Atherosclerotic Cardiovascular Disease, Atherosclerotic Plaque
- Trial name
- NCT06424860
- Testing
- Fish oil, Metformin, Fish Oil and Metformin
- Where
- 3 sites in Canada
- Volunteers
- 146 people
- Sponsor
- University of Alberta
Cancer, Other Malnutrition
Can Protein Intake be Increased Using Whole Foods Post-treatment in Cancer Patients?
Cancer and its treatments often result in severe toxicities and side effects that, over the course of treatment, results in weight loss and depletion of key nutrients.
- Trial name
- NCT05859100
- Testing
- ≥ 2 eggs in addition to usual diet for 8 weeks, ≥ 2 eggs in addition to usual diet for 4 weeks
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Alberta
Temporomandibular Disorders, Temporomandibular Joint Pain
Neck Exercises in Patients With Temporomandibular Disorders
Musculoskeletal (MSK) pain is a common reason to seek medical treatment. Temporomandibular disorders (TMDs) are MSK disorders that affect the masticatory muscles, the temporomandibular joint, and related structures in the neck…
- Trial name
- NCT03403998
- Testing
- Exercises
- Where
- Canada
- Volunteers
- 113 people
- Sponsor
- University of Alberta
Healthy
Cardiovascular Consequences of Inhaled Short-acting Beta-agonist Use
The goal of this clinical trial is to test the impact inhalers have on blood vessels in young healthy individuals. The main question it aims to answer is if long term use of asthma inhalers have any effect on the blood vessels…
- Trial name
- NCT06027606
- Testing
- Salbutamol 400mcg, Budesonide/formoterol
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Social Robots for Procedural Distress
Canada-UK AI Study
Children experience pain and distress in clinical settings every day. The negative consequences of unaddressed pain can be both short-term (e.g. fear, distress, inability to perform procedures) and long-term (e.g.
- Trial name
- Canada-UK AI (NCT06556329)
- Testing
- Robot (Intervention)
- Where
- 2 sites in Canada
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Transhumeral Amputation
Optimizing Transhumeral Osseointegration Prosthesis Control
Upper limb amputation above the elbow results in a significant loss of function. There have been many advancements in surgery and prosthetic devices to restore arm function, but many people still reject upper limb prostheses.
- Trial name
- NCT06853938
- Testing
- Myoelectric prosthesis
- Where
- 2 sites in Canada
- Volunteers
- 5 people
- Sponsor
- University of Alberta
Stress, Anxiety
Mindfulness in High Risk Pregnancies
Anxiety, depression and stress are common during pregnancy. These have been found to negatively impact mother and child outcomes.
- Conditions
- Stress, Anxiety, Depression, Mindfulness
- Trial name
- NCT04496115
- Testing
- Mindfulness
- Volunteers
- 60 people
- Sponsor
- University of Alberta
Pain, Perioperative
Reducing Pain From Retinal Laser With Vibrational Stimulation
The goal of this clinical trial is to learn if Vibration Anesthesia Device works to reduce pain during retinal laser for diabetic retinopathy.
- Trial name
- NCT06649604
- Testing
- Vibration Anesthesia Device, Panretinal Photocoagulation
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Neonatal Abstinence Syndrome
The Alberta Neonatal Abstinence Syndrome Mother-Baby Care ImprovEmeNT Program
Neonatal Abstinence Syndrome (NAS), is a common and costly problem in Alberta that affects approximately 250 babies per year exposed to drugs during pregnancy. Unfortunately, this has become more common in the last 10 years.
- Trial name
- NASCENT (NCT05226624)
- Testing
- Rooming-in care, Baseline standard of care
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- University of Alberta
Inflammatory Bowel Diseases, Crohn Disease
Fasting-mimicking Diet in Treatment of Depressive Symptoms in IBD
Inflammatory bowel disease (IBD) is a chronic illness characterized by inflammation of the intestine. Many individuals with IBD suffer from depressive symptoms and anxiety which can lead to a decreased quality of life, poor…
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- NCT05382897
- Testing
- Plant-based fasting-mimicking diet
- Where
- 2 sites in Canada
- Volunteers
- 42 people
- Sponsor
- University of Alberta
Chronic Obstructive Pulmonary Disease
Enhanced Pulmonary Rehabilitation With Digital Remote Home Monitoring
The primary objective of the current randomized controlled trial is to assess feasibility of integrating digital remote patient monitoring (dRPM) with the an enhanced Breathe Easy Pulmonary Rehabilitation Program for Individuals…
- Trial name
- NCT06077994
- Testing
- digital Remote Patient Monitoring+BEPR+ (dRPM+), Enhanced Breathe Easy Pulmonary Rehabilitation Program (BEPR+)
- Where
- Canada
- Volunteers
- 78 people
- Sponsor
- University of Alberta
Mild Cognitive Impairment (MCI)
A Game-based Screening for MCI Detection in Older Adults
This research explores a new and engaging way to screen for mild cognitive impairment (MCI) in older adults using a computer game instead of traditional paper-based tests.
- Trial name
- NCT07137650
- Where
- Canada
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Cirrhosis, Liver
Cirrhosis Care Alberta (CCAB): A Pragmatic Type II Hybrid Effectiveness Implementation Trial
Liver cirrhosis is the leading cause of morbidity and premature mortality in patients with digestive disease. There are many gaps in care which contribute to a high rate of hospital readmissions (44 percent at 90 days) and…
- Trial name
- CCAB (NCT04149223)
- Testing
- Evidence-based standardized Cirrhosis order set
- Where
- Canada
- Volunteers
- 3,975 people
- Sponsor
- University of Alberta
Diabetes Mellitus, Type 2, Surgery
Carbohydrate Loading and Diabetes in Colorectal Surgery
The goal of this study is to evaluate the feasibility of conducting a large study that would assess the safety of carbohydrate drinks (i.e. juice) prior to elective colorectal surgery in patients with type 2 diabetes.
- Conditions
- Diabetes Mellitus, Type 2, Surgery, Surgery--Complications
- Trial name
- NCT04410419
- Testing
- Pre-operative carbohydrate drink
- Where
- Canada
- Volunteers
- 71 people
- Sponsor
- University of Alberta
Mild Cognitive Impairment, Dementia
SCGs as a Proxy for Determining the Cognitive Status of Older Adults
Detecting memory problems early is crucial for treating conditions like Mild Cognitive Impairment (MCI), which often leads to dementia. Currently, doctors use tests in clinics to check for these issues.
- Conditions
- Mild Cognitive Impairment, Dementia, Alzheimer Disease, Healthy Aging
- Trial name
- NCT06367231
- Testing
- VibrantMinds
- Where
- 8 sites in Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Class II Malocclusion
Modified Herbst Approach to Improve Chin Projection
This study will collect data to try to assess which one of the two management options works better. The first option involves the use of the bite corrector first and then braces, while the second option involves the temporary…
- Trial name
- NCT05597748
- Testing
- Modified Herbst Approach, Conventional Herbst Approach
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta