Clinical trials: sponsored by University of Alberta
Major Depressive Disorder
Group CBT and Exercise in Management of Depression
INTRODUCTION: There is strong evidence indicating the effectiveness of Cognitive-Behavior Therapy (CBT) in the management of Major Depressive Disorder (MDD) and some clinical trials indicating physical exercise (PE) as an…
- Trial name
- NCT03731728
- Testing
- Group CBT, Group exercise
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of Alberta
Perinatal Stroke
Intensive Motor Training After Perinatal Stroke to Enhance Walking
Early childhood injuries such as perinatal (around birth) stroke are devastating because the child lives with the problem for life, typically close to a normal lifespan.
- Trial name
- NCT01773369
- Testing
- Early leg training, Delayed leg training, Parent leg training
- Where
- 2 sites in Canada
- Volunteers
- 33 people
- Sponsor
- University of Alberta
Spastic Diplegia
Early Intensive Exercise to Improve Walking in Children With Spastic Diplegia
This is a randomized controlled trial comparing 3 months of intensive leg exercise to standard physiotherapy care for the improvement of motor function in the legs in young children with spastic diplegia.
- Trial name
- NCT03166293
- Testing
- Intensive leg training with a physical therapist
- Where
- 2 sites in Canada
- Volunteers
- 4 people
- Sponsor
- University of Alberta
Hypertension
Telemonitoring and Protocolized Case Management for Hypertensive Community Dwelling Seniors With Complex Care Needs
Hypertension affects over 70% of Canadians over the age of 65y. Seniors with hypertension are at high risk for cardiovascular disease and death. Most of this risk is mediated through high blood pressure (BP).
- Trial name
- TECHNOMED (NCT02721667)
- Testing
- Telemonitoring, Case Management
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Alberta
Ascites Hepatic
Prospective Evaluation of PleurX Drain for Treatment of Cirrhotic Refractory Ascites
Refractory ascites (fluid build up in the abdomen that can not bet managed by medications) occurs in at least 10% of patients with end stage liver disease (cirrhosis).
- Trial name
- NCT04569565
- Testing
- PleurX catheter
- Volunteers
- 12 people
- Sponsor
- University of Alberta
Diabetes Mellitus, Type 2
Pre-operative Carbohydrate Loading Patients With Diabetes Undergoing Elective Colorectal Surgery
Goal to evaluate the feasibility of conducting a large study that would assess the safety of carbohydrate drinks (i.e. juice) prior to elective colorectal surgery in patients with type 2 diabetes.
- Trial name
- NCT04495114
- Testing
- 40g carbohydrate load (Apple juice)
- Where
- Canada
- Volunteers
- 71 people
- Sponsor
- University of Alberta
Child Behavior, Acute Pain
Improving Children's Cooperation During Dental Injection
This clinical trial aims to investigate how to increase children cooperation in dental settings using ideas adopted from psychology to make an effective interdisciplinary approach.
- Trial name
- NCT03978390
- Testing
- behavioral priming, endowment effect, Positive reinforcement
- Sponsor
- University of Alberta
Neoplasms, Head and Neck, Trismus
Manual Therapy and Use of the Dynasplint for Trismus in Patients With Head and Neck Cancer
The objectives of this pilot study are to determine the effectiveness of a manual therapy (MT) protocol plus the use of a dynamic jaw opening device on the maximal interincisor distance; on trismus symptoms; on pain-disability…
- Trial name
- NCT03178110
- Testing
- Physical therapy and dynasplint
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- University of Alberta
Breast Neoplasms, Lymphedema
Night-time Compression Systems for Breast Cancer Related Lymphedema
Women who have undergone breast cancer surgery may develop swelling of the arm on the side the breast cancer occurred. If the swelling becomes chronic it is called lymphedema.
- Trial name
- NCT01550250
- Testing
- Night-time compression system garment, Day-time compression sleeve
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of Alberta
Ischemic Stroke, Transient Ischemic Attack
Eliquis Acute Stroke Safety Evaluation
Study Design: This is an investigator-initiated prospective, open label, single arm phase IV study. Patients with documented non-valvular atrial fibrillation (AF) with acute TIA (defined as acute focal neurological deficits, with…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Atrial Fibrillation
- Trial name
- EASSE (NCT04435418)
- Testing
- Apixaban
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Ischemic Attack, Transient, Stroke
Canadian Pradaxa Acute Stroke Safety Study
Study Design: This is a multicentre, prospective, open-label, single arm, phase IV registry study. No additional procedures are included in the study. Standard clinical data will be collected.
- Trial name
- CPASS (NCT02415855)
- Testing
- Dabigatran
- Where
- 2 sites in Canada
- Volunteers
- 101 people
- Sponsor
- University of Alberta
Cognitive Function 1, Social
Evaluating Cognitive and Functional Impairment in Alzheimer's Dementia With a Ketogenic Diet.
The present study is being done in a scientifically rigorous manner, using readily available MCT oil (refined from coconut oil) versus a placebo oil to assess any cognitive and functional benefits for AD patients.
- Trial name
- NCT04396015
- Testing
- Bulletproof Brain Octane
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Pharmacokinetics
Ketone Levels Achieved After Medium Chain Triglyceride (MCT) Oil
Assessing Ketone levels achieved after varying doses of Medium Chain Triglyceride (MCT) oil
- Trial name
- NCT04389983
- Testing
- Medium Chain Triglyceride oil
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Shoulder Pain, Head Neck Cancer
Brief Intraoperative Electrical Stimulation for Prevention of Shoulder Dysfunction After Oncologic Neck Dissection
Introduction: Shoulder pain and dysfunction is common after oncologic neck dissection for head and neck cancer (HNC). These symptoms can hinder postoperative rehabilitation and oral hygiene, activities of daily living (ADLs), and…
- Trial name
- ESSAN (NCT02268344)
- Testing
- Grass SD9 Stimulator
- Where
- Canada
- Volunteers
- 68 people
- Sponsor
- University of Alberta
Obesity, Metabolic Syndrome
FMT and Fiber in Patients With Metabolic Syndrome
This study is looking at the safety and effectiveness of stool transplant, also known as Fecal Microbiota Transplantation (FMT) and prebiotic supplementation in the management of metabolic syndrome.
- Trial name
- FMT (NCT03727321)
- Testing
- Fecal Microbial Transplant, Fiber, Cellulose
- Where
- 2 sites in Canada
- Volunteers
- 68 people
- Sponsor
- University of Alberta
Overweight and Obesity
The Alberta FYBER (Feed Your Gut Bacteria morE fibeR) Study
Too much body-fat has been linked to a low-grade inflammation throughout the body. This inflammation is thought to then cause different diseases, like heart disease and diabetes.
- Trial name
- NCT02322112
- Testing
- Microcrystalline Cellulose Supplementation, Acacia Gum Supplementation, Resistant Starch Type 4 Supplementation
- Where
- Canada
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Blood Pressure
Assessing the Accuracy of the A&D TM-2657W Oscillometric Device
The A\&D automatic blood pressure device is a new kiosk that can measure blood pressure in the general population. The investigators plan to use the existing International Standards Organization validation protocol to determine…
- Trial name
- NCT04238442
- Testing
- A&D TM-2657W oscillometric device
- Where
- Canada
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Colorectal Cancer, Colorectal Polyps
Urine Metabolomics and Colorectal Cancer Screening
This is a prospective, multi-centered study to assess whether urine metabolomics can play a role in the screening of colorectal cancer (CRC).
- Trial name
- NCT01486745
- Where
- Canada
- Volunteers
- 2,175 people
- Sponsor
- University of Alberta
Urinary Tract Infections
An Open-label Trial to Evaluate the Safety of an Essential Oil Infused Perineal Towel
The purpose of this study is to assess the safety (absence of skin irritation) of a feminine hygiene product for perineal hygiene prior to undertaking a clinical effectiveness trial.
- Trial name
- WIPEAWAY (NCT02509403)
- Testing
- Essential oils infused Perineal Hygiene wipe
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Chronic Obstructive Pulmonary Disease, Pulmonary Fibrosis
Using Health-related Quality of Life (HRQL) in Routine Clinical Care
The objective of this study is to assess the effects of using HRQL measures in the clinical care of pre- and post-lung transplant patients.
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Fibrosis, Pulmonary Hypertension, Cystic Fibrosis
- Trial name
- NCT00457301
- Testing
- HUI score card
- Where
- Canada
- Volunteers
- 213 people
- Sponsor
- University of Alberta