Clinical trials: sponsored by University of Alberta
Lung Cancer
Therapeutic Yoga and Resistance Exercise for Lung Cancer
The purpose of the study is to determine the feasibility and preliminary efficacy of a combined therapeutic yoga and resistance exercise intervention for individuals with lung cancer and their caregivers.
- Trial name
- ASSURE (NCT03084692)
- Testing
- Therapeutic Yoga and Resistance Exercise
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Ischemic Stroke, Transient Ischemic Attacks
Preventing Recurrent Vascular Events in Patients With Stroke or Transient Ischemic Attack
People who have had a stroke or transient ischemic attack (TIA or "mini-stroke") are at high risk of having another stroke or a heart attack.
- Trial name
- PREVENTION (NCT00931788)
- Testing
- Antihypertensive agents and lipid lowering therapy, Usual Care
- Where
- Canada
- Volunteers
- 279 people
- Sponsor
- University of Alberta
Myocardial Infarction
Feasibility and Effectiveness of Remote Virtual Reality-Based Cardiac Rehabilitation
Regular exercise in patients who have heart disease is highly beneficial and improves quality of life and survival. Exercise training is considered a core component of cardiac rehabilitation (CR), which is a multicomponent…
- Trial name
- NCT02711631
- Testing
- MedBIKE
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of Alberta
Chronic Rhinosinusitis
Early Saline Irrigation to Decrease Post-operative Endoscopic Debridement
Nasal saline is a common treatment adjunct in the post-operative setting for endoscopic sinus surgery. However, the ideal timing and quantity of irrigation in the early post-operative period remains unknown.
- Trial name
- NCT01943370
- Testing
- Early saline irrigation, Routine Irrigation
- Volunteers
- 25 people
- Sponsor
- University of Alberta
Children Requiring IV Placement
Distraction to Reduce Pain and Distress in the Pediatric Emergency Department
Many medical procedures aimed at helping children can cause them pain and distress. If children have certain levels of pain or distress, it can have long lasting negative effects.
- Trial name
- NCT02326623
- Testing
- distraction, topical anesthetic cream
- Where
- Canada
- Volunteers
- 85 people
- Sponsor
- University of Alberta
Atherosclerosis, Complications of Diabetes Mellitus
18F-Sodium Fluoride (18F-NaF) PET-CT Imaging to Identify Vulnerable Plaques in Patients With Diabetes
Coronary artery calcification is a sign of heart disease. A nuclear medicine PET-CT test using sodium fluoride (18F-NaF) radioisotope has been shown to help identify growing calcification plaques early on in the disease process.
- Trial name
- D-NaF (NCT03530176)
- Testing
- 18Fluoride-Sodium Fluoride radio-isotope
- Where
- Canada
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Atrial Fibrillation, Thrombus Due to Heart Valve Prosthesis
The Effect of Medication Timing on Anticoagulation Stability in Users of Warfarin: The "INRange" RCT
Warfarin is an anticoagulant medication that is highly effective at preventing clotting disorders but which has a narrow therapeutic window.
- Conditions
- Atrial Fibrillation, Thrombus Due to Heart Valve Prosthesis, Deep Venous Thrombosis, Thromboembolism
- Trial name
- NCT02376803
- Testing
- Warfarin
- Where
- 2 sites in Canada
- Volunteers
- 217 people
- Sponsor
- University of Alberta
Prostate Cancer
Prostate Cancer Survivors Moving Toward Exercise (PROMOTE) Trial
The primary purpose of the study is to determine the effects of an implementation intention intervention on physical activity (PA) behaviour in prostate cancer survivors.
- Trial name
- PROMOTE (NCT01410656)
- Testing
- Telephone Implementation Intention, Self-completed implementation intention
- Where
- Canada
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Burning Mouth Syndrome
Effectiveness of Mucolox® and Clonazepam in Treatment of Burning Mouth Syndrome
What affect does the use of a mucoadhesive drug delivery system (Mucolox®) compounded with clonazepam have in the treatment of burning mouth syndrome? There are no clinical trials reported in the literature that evaluate the use…
- Trial name
- NCT02690844
- Testing
- Clonazepam mixed with Mucolox®, Mucolox® alone, Clonazepam
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Urinary Tract Infections
Outcomes of Urinary Tract Infection Management by Pharmacists
Pharmacists in some Canadian jurisdictions have recently been granted the ability to prescribe for uncomplicated urinary tract infections (UTIs).
- Trial name
- RxOUTMAP (NCT03184818)
- Testing
- Advanced care
- Where
- Canada
- Volunteers
- 750 people
- Sponsor
- University of Alberta
Ulcerative Colitis
Personalized "Alberta" Diet for Prevention of Relapse in Ulcerative Colitis
In the present study, ulcerative colitis (UC) patients in the remission stage of the disease will be randomized into two groups: Alberta anti-inflammatory diet and Canada's Food Guide diet.
- Trial name
- NCT02093780
- Testing
- Alberta Anti-inflammatory diet, Canada's Food Guide Diet
- Where
- Canada
- Volunteers
- 53 people
- Sponsor
- University of Alberta
End Stage Renal Disease
Risk Factors for Coronary Artery Calcification and Left Ventricular Hypertrophy in Hemodialysis Patients
Individuals with kidney disease are at a higher risk for heart and vascular diseases, including heart attacks and strokes, than those with normal kidney function.
- Trial name
- NCT01427374
- Where
- 4 sites in United States, Canada
- Volunteers
- 30 people
- Sponsor
- University of Alberta
Cerebral Infarction, Brain Ischemia
Penumbral Based Novel Thrombolytic Therapy in Acute Ischemic Stroke
Rationale The only proven therapy for acute stroke is tPA within 4.5 hours of symptom onset. This is the standard of care for patients presenting to our hospital within that time frame.
- Conditions
- Cerebral Infarction, Brain Ischemia, Stroke
- Trial name
- TIAS (NCT02101606)
- Testing
- Tenecteplase (TNK) (0.25 mg/kg, to maximum of 25mg)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Coronary Artery Disease
Outcomes of Angiotensin Converting Enzyme Inhibitor Management Strategies Prior to Coronary Artery Bypass
Coronary artery disease is a leading cause of death, hospitalization, and health care costs in developed nations. Coronary revascularization with coronary artery bypass graft (CABG) surgery improves the long term survival in…
- Trial name
- COMPACT (NCT02096406)
- Testing
- ACE/ARB continuation, ACE/ARB withdrawal
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- University of Alberta
Obesity
Extension of the 5As Team Study for Improved Provider Obesity Management to Physicians and Medical Trainees (Part 2)
Results from the 5As Team (5AsT) Study have identified critical gaps in medical school curricula on obesity, leading to a wave of new family physicians who lack confidence and are poorly equipped to manage obesity with their…
- Trial name
- 5AsT-MD2 (NCT02648308)
- Testing
- Obesity Management Workshop
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Stroke
A Home-based Intervention to Reduce Sedentary Behaviour and Improve Function After Stroke
The traditional approach to physical activity promotion in people with stroke has always emphasized activities of a moderate-to-vigorous intensity (i.e. moving enough to breathe fast and break a sweat).
- Trial name
- STUFFS (NCT02980744)
- Testing
- Sedentary behaviour intervention
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University of Alberta
Congenital Heart Disease
Infant Nasal Nitric Oxide Levels in Congenital Heart Disease
This pilot study aims to measure nasal nitric oxide (nNO) in a group of neonates and infants (≤ 12 months) with congenital heart disease (CHD) and compare their nNO levels to age matched controls without CHD.
- Trial name
- NCT02551107
- Testing
- Measurement of nasal Nitric Oxide level
- Where
- Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Heart Failure
The VO2 Increase With Testosterone Addition - Heart Failure (VITA-HF) Trial
Evaluate the efficacy and safety of testosterone supplementation on functional capacity, biomarkers, quality of life and clinical outcomes for patients with heart failure.
- Trial name
- VITA-HF (NCT01469988)
- Testing
- Testosterone
- Where
- 7 sites in Canada
- Volunteers
- 318 people
- Sponsor
- University of Alberta
Coronary Artery Bypass Grafting, Cardiopulmonary Bypass
Protection of the Heart With Doxycycline During Coronary Artery Bypass Grafting
The purpose of this study is to determine whether doxycycline (Periostat) at a sub-antimicrobial dose will decrease reperfusion injury after coronary artery bypass grafting (CABG) surgery with cardiopulmonary bypass (CPB).
- Conditions
- Coronary Artery Bypass Grafting, Cardiopulmonary Bypass, Reperfusion Injury
- Trial name
- NCT00246740
- Testing
- Periostat
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Alberta
Congenital Heart Disease
The CHAPTER II Study - Congenital Heart Adolescents Participating in Transition Evaluation Research
Transition is the planned movement of teens with chronic conditions from child-centered to adult-oriented healthcare. National bodies have published detailed guidelines about the importance of helping teens move to adult…
- Trial name
- NCT01723332
- Testing
- Educational, Self management
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- University of Alberta