Clinical trials: sponsored by University of Calgary
Oculopharyngeal Muscular Dystrophy, Muscular Dystrophies
Expiratory Muscle Strength Training (EMST) in Neuromuscular Disorders
The purpose of this study is to investigate the impact of expiratory muscle strength training (EMST) on the swallowing, breathing, oral intake, quality of life and cough function of people with oculopharyngeal muscular dystrophy…
- Conditions
- Oculopharyngeal Muscular Dystrophy, Muscular Dystrophies, Myopathy; Hereditary
- Trial name
- NCT04009408
- Testing
- Expiratory muscle strength therapy (EMST150, Aspire LLC)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Total Knee Arthroplasty, Anterior Cruciate Ligament Reconstruction
Impact of Crutch Type on Gait and Functional Outcomes Post-knee Surgery
Study withdrawn
- Trial name
- NCT04258917
- Testing
- Study withdrawn
- Sponsor
- University of Calgary
Cancer
EXCEL: Technology and Exercise Adherence
Exercise adherence and maintenance in the EXCEL program supported with a smart phone application: A pilot randomized controlled trial
- Trial name
- NCT04790578
- Testing
- ZoeInsights Application, EXCEL Exercise Class
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- University of Calgary
Infant, Premature, Diseases, Infant
The Alberta BLOOM Long Term Follow Up Study
This is a prospective, observational clinical cohort study involving children born very preterm at less than 31 weeks and six days gestation.
- Conditions
- Infant, Premature, Diseases, Infant, Asthma, Asthma in Children
- Trial name
- BLOOM-LTFU (NCT04641000)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Calgary
Young Adult Cancer, Young Adult Oncology
Yoga for Young Adults Affected by Cancer
Yoga may enhance physical and psychological outcomes among young adults affected by cancer. Yet, yoga has rarely been studied in this population.
- Trial name
- NCT05314803
- Testing
- Yoga
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- University of Calgary
Infant, Premature, Infants, Extremely Premature
The Alberta BLOOM Preterm Neonate Study
This is a prospective, observational clinical cohort study involving 100 mothers and their very preterm infants born at less than 32 weeks gestation.
- Conditions
- Infant, Premature, Infants, Extremely Premature, Microbiota, Gastrointestinal Microbiome
- Trial name
- BLOOM-PTN (NCT03840980)
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University of Calgary
Cancer, Head and Neck Cancer
EXCEL: Exercise for Cancer to Enhance Living Well
Project EXCEL will provide community or online exercise programs to rural and remote and under-served cancer survivors, as well as encourage participants to become life-long exercisers.
- Conditions
- Cancer, Head and Neck Cancer, Colon Cancer, Breast Cancer
- Trial name
- EXCEL (NCT04478851)
- Testing
- Group Exercise Classes
- Where
- 3 sites in Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Anorexia in Adolescence
Finding Treatments for Eating Disorders
Currently, Family Based Treatment (FBT) is the leading evidence-based, manualized treatment for adolescents with anorexia nervosa (AN).
- Trial name
- FED (NCT05249140)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Calgary
Head and Neck Cancer, Head and Neck Neoplasms
Prehabilitation and Recovery After Head and Neck Cancer Surgery
Implementing a multiphasic, multimodal prehabilitation intervention for people undergoing surgery with free flap reconstruction for the treatment of head and neck cancer.
- Conditions
- Head and Neck Cancer, Head and Neck Neoplasms, Surgery
- Trial name
- NCT04598087
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of Calgary
Crohn Disease
Can Intermittent Fasting Induce Weight Loss and Improve Gut Health as Compared to Standard Medical Care in Patients With Obesity/High BMI and Crohn's Disease.
Diet is a determinant of gut microbial diversity and composition and is recognized as a potential environmental trigger for IBD; for example, high-fat diets are associated with increased risk of CD in pre-clinical models, with…
- Trial name
- CD-Fast (NCT05230160)
- Testing
- Intermittent Fasting
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Calgary
Major Depressive Disorder
Adjunctive D-Cycloserine in Major Depressive Disorder
Transcranial magnetic stimulation (rTMS) is an approved treatment for depression. The purpose of this study is to test an adjunctive medication, D-cycloserine, in rTMS for depression using a placebo-controlled design.
- Trial name
- NCT03937596
- Testing
- D-cycloserine, Transcranial Magnetic Stimulator
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Major Depressive Disorder
Cycloserine rTMS Plasticity Augmentation in Depression
Transcranial magnetic stimulation (rTMS) is an investigational and therapeutic modality that impacts the connection strength between neurons by delivering patterned energy.
- Trial name
- NCT03511599
- Testing
- Cycloserine, Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Calgary
Synaptic Plasticity
Roflumilast TMS-EEG Plasticity
Repetitive transcranial magnetic stimulation (rTMS) uses a magnetic field to non-invasively induce electrical function within the brain.
- Trial name
- NCT04369547
- Testing
- Transcranial Magnetic Stimulation, Roflumilast
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Calgary
Diabetes, Diabetes Complications
Pressure-Sensing Insoles in the Neuropathic Ulcer Treatment Pathway
Diabetic foot ulceration (DFU) is a common complication with a 25% lifetime risk in patients with diabetes. While most of these ulcers can be treated successfully on an outpatient basis, some will persist and become infected.
- Conditions
- Diabetes, Diabetes Complications, Neuropathy, Peripheral Neuropathy
- Trial name
- PINUP (NCT02586519)
- Testing
- SurroSense Rx System
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Calgary
Tic Disorders
TICS: Transcranial Magnetic Stimulation for Intervening in Children With Tourette's Syndrome (CIHR)
Tourette's Syndrome (TS) is characterized by repetitive movements and vocalizations called tics. Due to the suffering caused by TS, children and adolescents often require treatment for their tics.
- Trial name
- TICS-CIHR (NCT03844919)
- Testing
- rTMS + CBIT
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Non-Alcoholic Fatty Liver Disease, Hepatitis B
A Prospective Study of HBV Immunity and HBV Vaccination in Patients With NAFLD in Canada
(1) Due to missed childhood vaccination programs, the majority of adult patients with NAFLD in Canada do not have immunity to hepatitis B.
- Conditions
- Non-Alcoholic Fatty Liver Disease, Hepatitis B, Vaccine Reaction
- Trial name
- NCT02985450
- Testing
- Engerix-B
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- University of Calgary
Stroke
Robotic Evaluations of Motor Learning During Stroke Neurorehabilitation
The RELEARN trial is a a prospective longitudinal cohort study sampled by convenience. Stroke survivors and healthy control individuals will be recruited to analyze motor learning in the upper extremity and its neural basis in…
- Trial name
- RELEARN (NCT05106140)
- Testing
- Magnetic Resonance Imaging (MRI), Kinarm Robotic Exoskeleton Assessment, Clinical Assessment
- Where
- 4 sites in Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Whiplash Injuries, Neck Injuries
Effectiveness of Physiotherapy Following PRP for Chronic Whiplash
The investigators will explore a standardized and previously published evidence-based conservative multimodal physiotherapy treatment fulfilling clinical practice guidelines in individuals with chronic whiplash-associated…
- Conditions
- Whiplash Injuries, Neck Injuries, Platelet Rich Plasma
- Trial name
- NCT03949959
- Testing
- Multimodal physiotherapy
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- University of Calgary
Postural Tachycardia Syndrome
Hemodynamic Effects of Compression in POTS
When an individual with Postural Tachycardia Syndrome (POTS) stands up, their heart rate increases significantly (>30BPM) and they may experience symptoms such as lightheadedness, dizziness, shortness of breath, nausea and mental…
- Trial name
- NCT03484273
- Testing
- LifeWrap Compression Garment
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Calgary
Rotator Cuff Tears
Arthroscopic Rotator Cuff Repair Utilizing Mechanical Bone Debridement Versus Coblation Debridement
Randomized controlled trial comparing coblation debridement to mechanical debridement in rotator cuff repair.
- Trial name
- FLOW90 (NCT05084781)
- Testing
- Coblation Debridement (FLOW90)
- Where
- Canada
- Volunteers
- 94 people
- Sponsor
- University of Calgary