Clinical trials: sponsored by University of Calgary
Pain, Postoperative
Pain After Tonsillectomy Study
Pain is a common experience in childhood. Healthy children can undergo up to 20 painful procedures by the age of 5. Moreover, millions of children undergo surgery (e.g., tonsillectomies) each year, which is commonly linked to…
- Trial name
- PAT (NCT03538730)
- Testing
- Memory Reframing
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Syncope, Vasovagal, Neurally-Mediated
Clinical Trial for the Prevention of Vasovagal Syncope
The main question in the study is whether people taking fludrocortisone are less likely to faint than people taking an inactive pill called a placebo. Fludrocortisone is a drug that stimulates the body to retain salt and water.
- Trial name
- NCT00118482
- Testing
- fludrocortisone acetate
- Where
- 14 sites in United States, Canada
- Volunteers
- 213 people
- Sponsor
- University of Calgary
Multiple Sclerosis
Safety and Tolerability of Quetiapine in Multiple Sclerosis
Study Purpose: The purpose of this clinical trial is to determine if extended-release quetiapine in a dose of 300 mg daily is tolerable to people with relapsing remitting and progressive MS.
- Trial name
- NCT02087631
- Testing
- Extended-release quetiapine fumarate
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Calgary
Multiple Sclerosis, Relapsing-Remitting
Pilot Trial of Domperidone in Relapsing-Remitting Multiple Sclerosis (RRMS)
The first major objective of this pilot trial is to demonstrate that it is possible to study myelin repair in relapsing-remitting multiple sclerosis (RRMS) patients with enhancing lesions on MRI by using advanced imaging…
- Trial name
- NCT02493049
- Testing
- Domperidone
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- University of Calgary
Type 1 Diabetes, Neuropathy
Corneal Confocal Microscopy to Detect Diabetic Neuropathy in Children
The overall aim of this study is to confirm the utility of corneal confocal microscopy (CCM) as a new technique to rapidly and non-invasively assess diabetic neuropathy (DN) in children.
- Conditions
- Type 1 Diabetes, Neuropathy, Retinopathy
- Trial name
- CCM (NCT02321904)
- Testing
- Corneal Confocal Microscopy, Nerve Conduction Studies, Quantitative sensory testing
- Where
- Canada
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Pain, Traumatic Limb Injury
Pre-hospital Care With Intra-Nasal Ketamine for Transport (PRECINKT): A Pilot Study
The investigators hypothesize that intra-nasal ketamine, for analgesia of patients with moderate to severe pain in an alpine setting, will provide a clinically significant reduction in pain and provide an effective and feasible…
- Trial name
- PRECINKT (NCT02033434)
- Testing
- Intranasal Ketamine
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Premature Birth
Family Integrated Care (FICare) in Level II NICUs
In Alberta, nearly one in every twelve babies is born too soon (preterm). Preterm babies are at greater risk for breathing and feeding problems, as well as infections, than babies born on their due date (full term).
- Trial name
- FICare (NCT02879799)
- Testing
- Implement Family Integrated Care
- Where
- 10 sites in Canada
- Volunteers
- 765 people
- Sponsor
- University of Calgary
Acute Spinal Cord Injury
Mean Arterial Blood Pressure Treatment for Acute Spinal Cord Injury
Current guidelines for the clinical management of acute spinal cord injury (SCI) recommend maintenance of mean arterial blood pressure (MAP) at 85 to 90 mmHg for the first seven days after SCI as a clinical option.
- Trial name
- MAPS (NCT02232165)
- Testing
- Hypotension avoidance, Induced hypertension
- Where
- 2 sites in United States, Canada
- Volunteers
- 17 people
- Sponsor
- University of Calgary
Healthy, Pediatrics
Pediatric Transcranial Static Magnetic Field Stimulation to Improve Motor Learning
Non-invasive brain stimulation (NIBS) is a safe, painless way to improve brain function. It is used for many conditions, including to help children with disabilities.
- Trial name
- PSTIM (NCT03949712)
- Testing
- Transcranial Static Magnetic Field Stimulation (tSMS)
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Head and Neck Neoplasms
Exercise After Radiation for Head & Neck Cancer
People who receive radiation therapy for head and neck cancer (HNC) can experience side-effects which include a significant loss in body mass and a loss of muscle mass (cancer cachexia).
- Trial name
- NCT04013178
- Testing
- Accentuated eccentric loading + electromyostimulation, Conventional resistance training
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Calgary
Magnetic Resonance Imaging
The Use of a Mock MRI Scanner for Reducing the Use of Anesthesia in Children Undergoing Clinical MRI Scans
Diagnostic Magnetic Resonance (MR) imaging procedures can be stressful for children and parents. Patients must lie still during the procedure to provide diagnostic quality images.
- Trial name
- NCT02630342
- Testing
- Mock MRI scanner, Preparation materials, Child Life Specialist preparation
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of Calgary
Peripheral Arterial Disease, Critical Limb Ischemia
Exercise Rehabilitation for Patients With Critical Limb Ischemia After Revascularization
Peripheral arterial disease (PAD) affects more than 200 million people worldwide. This disease occurs with narrowing and occlusion of arteries supplying oxygenated blood to the organs and limbs.
- Trial name
- NCT03839953
- Testing
- Supervised Exercise Program, Best Medical Therapy
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Diabetes
Involvement of Community Pharmacists in Complex Care Plans for Diabetic Patients, a Pilot Study
This project is an initiative to bring physicians, nurses, community pharmacists and patients together in collaborative planning in the management of diabetes, which aligns with the collaborative, team based aspects of family…
- Trial name
- NCT02399332
- Testing
- Community pharmacist involvement
- Volunteers
- 16 people
- Sponsor
- University of Calgary
Malnutrition, Inflammatory Bowel Disease 1
Pre-Operative Parenteral Nutrition in Malnourished Patients
Malnourished patients with IBD that receive pre-operative parenteral nutrition therapy will have fewer post-operative complications compared to malnourished patients that receive standard of care nutritional therapy.
- Trial name
- NCT02985489
- Testing
- Olimel Parenteral Nutrition
- Sponsor
- University of Calgary
Cervical Dystonia
A Multicenter Pilot Study of Pallidal Deep Brain Stimulation for Cervical Dystonia
The purposes of this study are: to determine if bilateral pallidal deep brain stimulation results in improvement in neck postures/movements; to determine if bilateral pallidal deep brain stimulation results in improvement in…
- Trial name
- NCT00132990
- Testing
- Deep brain stimulation
- Where
- 5 sites in Canada
- Volunteers
- 10 people
- Sponsor
- University of Calgary
Depression, Men
The Effects of E-mental Health Program and Job Coaching on the Risk of Major Depression in Canadian Working Men
There is a pressing need for innovation in prevention of major depression in male workers. Major depression (MDE) affects workers' health and productivity.
- Trial name
- NCT02777112
- Testing
- e-mental health program, e-mental health program and job coaching, No intervention
- Where
- Canada
- Volunteers
- 1,133 people
- Sponsor
- University of Calgary
Pressure Ulcer
Pressure Sensing to Reduce the Risk of Pressure Ulcer Formation
Pressure ulcers are prevalent conditions that result in substantial financial costs to the healthcare system as well as significant distress to affected patients and their families.
- Trial name
- NCT02325388
- Testing
- ForeSite PT™ system
- Where
- Canada
- Volunteers
- 678 people
- Sponsor
- University of Calgary
Spinal Cord Injuries
Exoskeleton Use in Acute Rehab Post Spinal Cord Injury; a Safety and Feasibility Study
This study will examine the safety and feasibility of using an exoskeleton in subjects who are less than 6 months post spinal cord injury (SCI).
- Trial name
- NCT03144830
- Testing
- Exoskeleton
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of Calgary
Delirium
Family ICU Delirium Detection Study
To evaluate the validity, reliability, and acceptability of employing family-administered delirium detection tools in the critically ill.
- Trial name
- FIDDS (NCT03379129)
- Where
- Canada
- Volunteers
- 147 people
- Sponsor
- University of Calgary
Nephrotic Syndrome in Children, Nephrotic Syndrome, Minimal Change
CHILDNEPH The Canadian Childhood Nephrotic Syndrome Study
CHILDNEPH is a pan-Canadian project to observe clinical care for children with nephrotic syndrome. Previous studies have indicated that there is wide practice variation in how health care providers treat this remitting and…
- Conditions
- Nephrotic Syndrome in Children, Nephrotic Syndrome, Minimal Change, Nephrotic Syndrome，Idiopathic
- Trial name
- CHILDNEPH (NCT03786263)
- Where
- 12 sites in Canada
- Volunteers
- 400 people
- Sponsor
- University of Calgary