Clinical trials: sponsored by University of Calgary
Injury of Shoulder Region, Rotator Cuff Syndrome
Rotator Cuff Surgical Outcomes in Women
The overall purpose of this work is to use a prospective cohort study to examine patient-specific but shoulder-extrinsic factors and how they influence the results of rotator cuff surgery.
- Trial name
- RCSOW (NCT02725320)
- Where
- Canada
- Volunteers
- 192 people
- Sponsor
- University of Calgary
Healthy, Pediatrics
Accelerating Motor Learning in Pediatrics
Non-invasive brain stimulation can both study and potentially treat neurological disorders. Transcranial direct-current stimulation (tDCS) is an emerging safe and tolerability form of stimulation and has been used increasingly…
- Trial name
- AMPED (NCT03193580)
- Testing
- Anodal Conventional tDCS, Anodal High Definition tDCS
- Where
- 2 sites in Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Brain Injuries, Traumatic, Concussion, Brain
rTMS Treatment of Persistent Headache and Post Concussion Symptoms Attributed to Mild Traumatic Injury to the Head
The objective of this study is to investigate the treatment effect of repetitive transcranial magnetic stimulation in patients with a history of both persistent post-traumatic headache and post-concussion symptoms.
- Conditions
- Brain Injuries, Traumatic, Concussion, Brain, Headaches Chronic, Headache
- Trial name
- TOPiCS-rTMS (NCT03691272)
- Testing
- rTMS - Real Air Film Coil
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Pre-Eclampsia
Identifying Methods for Postpartum Reduction of Vascular Events: Pilot Randomized Controlled Trial
IMPROVE is a pilot RCT with a behavioral intervention component (CardioPrevent program). The primary objectives of this pilot study are to assess the feasibility of the implementation of a postpartum CVD prevention lifestyle…
- Trial name
- IMPROVE (NCT03302260)
- Testing
- CardioPrevent® Program
- Volunteers
- 84 people
- Sponsor
- University of Calgary
Depressive Disorder, Treatment-Resistant
DBS for Treatment Resistant Depression
The purpose of this study is to examine the effects of sub-callosal cingulate (SCC) deep brain stimulation (DBS) in patients with treatment resistant depression (TRD).
- Trial name
- CRIO-DBS (NCT01983904)
- Testing
- deep brain stimulation with short & long pulse width
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Calgary
Medication Overuse Headache, Analgesic Overuse Headache
Frovatriptan as a Transitional Therapy in Medication Overuse Headache
This study will analyze the effectiveness of a medication called Frovatriptan, in the context of medication overuse headache (MOH). MOH is a headache that develops when pain-killers are taken frequently.
- Trial name
- NCT01044251
- Testing
- Frovatriptan
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University of Calgary
Type 1 Diabetes
Prebiotic Fiber Supplement in T1DM Children
The gut microbiome is increasingly recognized as a contributor to disease states. In type 1 diabetes, alterations in gut microbiota may be linked to changes in intestinal permeability, inflammation and insulin resistance.
- Trial name
- NCT02442544
- Testing
- Prebiotic
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- University of Calgary
Age-Related Osteoporosis
Dose-dependent Effects of Vitamin D on Bone Health
We propose to conduct a randomized double blind trial of three doses of vitamin D, 400, 4000, and 10,000 International Units (IU) per day, to assess the effect on bone density and architecture as assessed by high resolution…
- Trial name
- NCT01900860
- Testing
- Vitamin D
- Where
- Canada
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Prematurity
Oxygen Saturation and Caffeine Post-Discharge
This study aims to determine normative values of oxygen saturation in late preterm infants, and evaluate the frequency of hypoxic events in infants requiring caffeine at discharge and those not requiring it.
- Trial name
- OCPDPS (NCT02386046)
- Testing
- Pulse oxymeter measurements
- Where
- Canada
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Preterm Birth, Prematurity
Parent-child Interactions, Child Developmental Health, and Health System Costs at 6 Months Corrected Age
The aim of this novel health services research proposal is to assess the longer-term outcomes, to 6 months corrected age, of an adapted Family Integrated Care (FICare) model of care for moderate and late preterm infants admitted…
- Conditions
- Preterm Birth, Prematurity, Infant,Premature, Infant Development
- Trial name
- NCT03357458
- Testing
- Family Integrated Care
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Calgary
Hematologic Neoplasms
Use of Haploidentical Related Donors for Patients Without Matched Sibling, Unrelated Donor or Cord Blood Units
The administration of high-dose chemotherapy followed by the infusion of blood or bone marrow stem cells (stem cell transplantation) from a matched donor has become standard treatment for patients with high-risk or relapsed…
- Trial name
- NCT02504047
- Testing
- T-Cell replete haplo-transplant
- Where
- 5 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Refractory Epilepsy
Voronistat in Pediatric Patients With Drug Resistant Epilepsy
The study evaluates the safety, tolerability, and efficacy of Vorinostat in addition to standard of care anti-epileptic drugs in pediatric patients with medically refractory epilepsy.
- Trial name
- NCT03894826
- Testing
- Vorinostat 100 MG
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Calgary
Stroke
Robot and tDCS Based Proprioceptive Rehabilitation After Stroke
Proprioceptive deficits are common following stroke, yet current evidence-based approaches for rehabilitating proprioception are limited.
- Trial name
- RoboStim (NCT03888326)
- Testing
- 1x1 anodal tDCS, Robotic Rehabilitation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Cancer, Pain
Group Versus Individual Acupuncture for Cancer Pain
Typically, in North America, acupuncture is performed on an individual basis. However, community acupuncture, also known as group acupuncture, is an emerging method of treating patients.
- Trial name
- NCT03641222
- Testing
- Acupuncture
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- University of Calgary
Motor Activity
Cycloserine rTMS Plasticity Augmentation
Transcranial magnetic stimulation (rTMS) is an investigational and therapeutic modality that impacts the connection strength between neurons by delivering patterned energy.
- Trial name
- NCT03432689
- Testing
- Transcranial Magnetic Stimulation, Cycloserine
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Disturbances in Initiating and Maintaining Sleep, Parent-Child Relations
Play2Sleep: Using Play to Improve Infant Sleep
The objective of this study is to evaluate and explore the effectiveness of Play2Sleep on families of infants with infant sleep disturbances.
- Trial name
- NCT02742155
- Testing
- Play2Sleep, Comparison
- Where
- 9 sites in Canada
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Vancomycin Resistant Enterococci Infection, Clostridium Difficile Infection
Hospital Design and Risk of Nosocomial Infections: A Prospective Controlled Trial
With the construction of a new medical teaching ward with features designed to reduce hospital-acquired infections, we hypothesized that the design of the new ward was the major factor that contributed to the improved outcomes…
- Conditions
- Vancomycin Resistant Enterococci Infection, Clostridium Difficile Infection, Nosocomial Infection, Methicillin Resistant Staphylococcus Aureus Infection (MRSA)
- Trial name
- NCT00563186
- Testing
- Admission to a novel hospital ward
- Where
- Canada
- Volunteers
- 1,514 people
- Sponsor
- University of Calgary
Chronic Kidney Disease
A Cluster Randomized Trial to Assess the Impact of Patient and Provider Education on Use of Home Dialysis
Patients with severe kidney failure require dialysis or transplantation to survive. For those in whom a transplant is not an option, there are two main dialysis options: hemodialysis (either incenter or at home) or home…
- Trial name
- NCT02202018
- Testing
- Active KT intervention
- Where
- 2 sites in Canada
- Volunteers
- 55 people
- Sponsor
- University of Calgary
Schizophrenia
A Trial of Cognitive Training in Schizophrenia
Schizophrenia is associated with a wide range of symptoms impacting a number of different domains, including cognitive impairment.
- Trial name
- NCT02478827
- Testing
- Cognitive training
- Where
- 3 sites in Canada
- Volunteers
- 83 people
- Sponsor
- University of Calgary
Celiac Disease
A 12-week Exercise Program for Adults With Celiac Disease
Engagement in regular physical activity (PA) is associated with a range of physical and psychological benefits among chronic disease populations.
- Trial name
- MOVE-C (NCT03520244)
- Testing
- Exercise + Holistic Education
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Calgary