Clinical trials: sponsored by University of Malaya
Periodontitis
Probiotics as Adjunctive Therapy in the Management of Periodontitis
The goal of this clinical trials is to learn about the effect of taking Prodentis on a long term basis following periodontal therapy. The main question it aims to answer is 1.
- Trial name
- NCT07531875
- Testing
- Prodentis
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- University of Malaya
CLABSI - Central Line Associated Bloodstream Infection
Efficacy & Cost Effectiveness of Antimicrobial-impregnated CVCs in CLABSI Prevention in a Malaysia Adult ICU
Central venous catheters (CVCs) are indispensable in modern critical care. However, CVC usage is associated with complications, including central line-associated bloodstream infections (CLABSIs), which in turn, is translated to…
- Trial name
- NCT05959018
- Testing
- Arrow Three-Lumen Central Venous Catheter, Arrowg+ard Blue Plus® Three-Lumen Central Venous Catheter
- Where
- Malaysia
- Volunteers
- 110 people
- Sponsor
- University of Malaya
Stroke, Acute, Gait, Spastic
Rhythmic Auditory Stimulation as Pre-Gait Training for Improving Balance and Weight Shifting in Rehabilitation Patients
The purpose of this study is to explore whether Rhythmic Auditory Stimulation (RAS) as pre-gait training can help improve balance, weight-shifting abilities, and overall gait performance in stroke patients undergoing…
- Conditions
- Stroke, Acute, Gait, Spastic, Attention Impaired
- Trial name
- NCT06995092
- Testing
- Music therapy, Standard physiotherapy program
- Where
- Malaysia
- Volunteers
- 27 people
- Sponsor
- University of Malaya
Adolescent Idiopathic Scoliosis (AIS)
Small Study Comparing Two Pain Medicines in Teenagers for Pain Control After Scoliosis Corrective Surgery.
The goal of this clinical trial is to evaluate whether adding low-dose ketamine to PCA morphine reduces opioid requirements after posterior spinal fusion surgery in adolescent idiopathic scoliosis patients.
- Trial name
- KetaMorph (NCT07452705)
- Testing
- Ketamine-Morphine PCA, Morphine (Intravenous patient-controlled analgesia)
- Where
- Malaysia
- Volunteers
- 114 people
- Sponsor
- University of Malaya
Treatment, Growth Modification
Study of The Effects of Mandibular Advancement Aligners in Treating Children With Class II Division 1 Malocclusion
The goal of this clinical trial is to learn the effects of Mandibular Advancement Aligner in growth modification of children with Class II Division 1 malocclusion.
- Trial name
- NCT07420270
- Testing
- Mandibular Advancement Aligner
- Where
- Malaysia
- Volunteers
- 21 people
- Sponsor
- University of Malaya
Diabetes Mellitus, Diabetes Mellitus Type 2
Multilevel Ecological and COM-B Determinants of Medication Adherence in Adults With Diabetes
This observational study aims to understand why some adults with diabetes find it difficult to take their medicines as prescribed.
- Conditions
- Diabetes Mellitus, Diabetes Mellitus Type 2, Medication Adherence
- Trial name
- ADHECOM (NCT07420634)
- Testing
- Multilevel Ecological Determinants of Medication Adherence
- Where
- India
- Volunteers
- 220 people
- Sponsor
- University of Malaya
Liver Cirrhosis, Cognitive Dysfunction
The Liver Cirrhosis Cognitive Decline Scale (LiCCoS)
The goal of this observational study is to develop and test a new questionnaire called the Liver Cirrhosis Cognitive Decline Scale (LiCCoS) for adults with liver cirrhosis.
- Conditions
- Liver Cirrhosis, Cognitive Dysfunction, Hepatic Encephalopathy, Neurocognitive Disorders
- Trial name
- LiCCoS (NCT07418008)
- Where
- India
- Volunteers
- 230 people
- Sponsor
- University of Malaya
Postoperative Pain, Gynecologic Disease
Analgesic Effect of IntraPeritoneal LIGNOcaine in Gynaecological Open Surgery
The incidence of postoperative pain is highly prevalent among surgical patients. Inadequate postoperative pain control can slow the recovery and it increases the risk of postoperative complications, namely lung collapse and…
- Conditions
- Postoperative Pain, Gynecologic Disease, Local Anesthetic Systemic Toxicity
- Trial name
- NCT05897385
- Testing
- Lignocaine, Normal Saline
- Where
- Malaysia
- Volunteers
- 112 people
- Sponsor
- University of Malaya
Prostate Cancer, Procedural Pain Relief
AcuTENS for Pain Relief During TRUS-Guided Prostate Biopsy
This study evaluates whether transcutaneous electrical nerve stimulation applied at specific acupuncture points (AcuTENS) can reduce pain and anxiety during transrectal ultrasound-guided prostate biopsy for participants suspected…
- Conditions
- Prostate Cancer, Procedural Pain Relief, TRANSRECTAL ULTRASOUND-GUIDED PROSTATE BIOPSY, Transcutaneous Electrical Nerve Stimulation
- Trial name
- NCT07292337
- Testing
- Active AcuTENS
- Where
- Malaysia
- Volunteers
- 53 people
- Sponsor
- University of Malaya
Stroke
The Brain Symphony For Post-Stroke Rehabilitation
Music listening intervention has made great strides in improving the condition of stroke survivors. Thus, this research explores the effects of music listening intervention on post-stroke survivors during rehabilitation by using…
- Trial name
- NCT06239948
- Testing
- With Music, Without Music
- Where
- Malaysia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Diabetes Mellitus Type 2
Effect of Acute Protein Supplementation in Diabetic Patients
The goal of this trial is to test the effect of house cricket (Acheta domesticus) preload on glycemic response in diabetic patients.
- Trial name
- NCT06880614
- Testing
- Oral Glucose Tolerance test (75g 2-hour), Whey, House cricket
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- University of Malaya
Periodontitis, Rheumatoid Arthritis
Effect of Nonsurgical Periodontal Therapy (NSPT) on Rheumatoid Arthritis Subjects With Periodontitis
Periodontitis (PD), a chronic inflammatory disease which results in irreversible attachment loss, bone destruction and, if left untreated, tooth loss.
- Trial name
- NCT05880303
- Testing
- Nonsurgical periodontal therapy
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- University of Malaya
Breast Exicision Biopsy
Study Comparing Dynastat and Parestat Pain Relief Medications for Patients After Breast Surgery
The goal of this clinical trial is to learn if generic parecoxib (Parestat) works as well as the original drug (Dynastat) for treating pain after breast surgery. It will also learn about the safety of both drugs.
- Trial name
- PANDA (NCT07154446)
- Testing
- Parestat(generic parecoxib), Dynastat (original Parecoxib)
- Volunteers
- 60 people
- Sponsor
- University of Malaya
Postoperative Pain Management in Total Knee Arthroplasty
Dexmedetomidine as an Adjunct to Periarticular Ropivacaine in Total Knee Replacement: A Pilot Randomised Controlled Trial
This study aims to evaluate whether adding dexmedetomidine to ropivacaine-based periarticular infiltration (PAI) improves postoperative pain control in patients undergoing total knee replacement (TKR).
- Trial name
- NCT07176065
- Testing
- Ropivacaine + saline solution, Ropivacaine + Dexmedetomidine
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- University of Malaya
Bracket Bonding, Digital Application
ACCURATE ORTHODONTIC BRACKETS POSITIONING WITH OR WITHOUT DENTAL MAGNIFYING LOUPES
The goal of this clinical trial is to assess the accuracy of bracket positioning on tooth facial axis of clinical crown with dental loupes (L) or without dental loupes (NL) on orthodontic patients.
- Conditions
- Bracket Bonding, Digital Application, Technology-enhanced Learning
- Trial name
- NCT07134803
- Testing
- Bonding of the orthodontic brackets with dental loupe with Zumax Dental loupes DFK Angled Loupe with a magnification of x3.0 and focus depth of 42cm
- Where
- Malaysia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Dental Anxiety
Exploring Dental Anxiety in Special Needs Patients: A Comparison of I-MDAS and Malay MDAS
This study aims to better understand and improve how dental anxiety is measured in patients with special needs (PSN) who visit the Special Care Dentistry (SCD) Clinic at Universiti Malaya (UM).
- Trial name
- MDAS (NCT07121608)
- Where
- Malaysia
- Volunteers
- 56 people
- Sponsor
- University of Malaya
Nerve Condition
Intra-operative Steroid Irrigation for Reducing Recurrent Laryngeal Nerve Palsy Post-thyroidectomy
The main aim of this study is to elucidate whether the topical irrigation of steroid during thyroid surgery can reduce the rate of recurrent laryngeal nerve palsy as majority of nerve dysfunction was due to neuropraxia to…
- Trial name
- NCT07068048
- Testing
- Dexametasone, Water for injection
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- University of Malaya
Orthodontic Appliances, Removable, Orthodontic Appliance Complication
Microbial Adherence, Surface Roughness, Effectiveness and Impact on Patients Between Conventional and 3D Printed Twin Block Appliances
The Twin Block appliance is a removable orthodontic appliance that is used to help correct a backward positioned lower jaw in growing children.
- Conditions
- Orthodontic Appliances, Removable, Orthodontic Appliance Complication, Class II Malocclusion, Division 1
- Trial name
- NCT06944860
- Testing
- Conventional TBA, 3D TBA
- Where
- Malaysia
- Volunteers
- 32 people
- Sponsor
- University of Malaya
Crohn Disease
Dietary Modification In Inflammatory Bowel Disease Patients
This research project aimed to develop a culturally appropriate Asian Inflammatory Bowel Disease Diet for the Malaysian population, based on the Crohn's disease exclusion diet (CDED).
- Trial name
- NCT06871267
- Testing
- General Healthy Diet, Crohn's Disease Exclusion Diet (CDED)
- Where
- Malaysia
- Volunteers
- 74 people
- Sponsor
- University of Malaya
Vaginal Dryness
Assess Efficacy, Safety, and Tolerability of 8 Weeks of Vaginal Hyaluronic (V-HYAL) Gel in Peri- and Post-Menopausal Female
The goal of this clinical trial is to assess the efficacy of repeat doses of V-HYAL Gel on vaginal dryness in Peri- and Post-Menopausal Female.
- Trial name
- V-HYAL (NCT06964646)
- Testing
- Vaginal Hyal gel 2.5g
- Where
- Malaysia
- Volunteers
- 70 people
- Sponsor
- University of Malaya