Clinical trials: sponsored by University of Miami
Sjogren's Syndrome
Fecal Microbial Transplant (FMT) for Sjogrens Syndrome
This is an open label study to evaluate the effect of Fecal Microbiota Transplantation (FMT) on the gut microbiome and Systemic parameters.
- Trial name
- NCT03926286
- Testing
- FMP-30
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Miami
Infection Due to Resistant Organism
FMT for MDRO Colonization in Solid Organ Transplant
This is a pilot feasibility study to determine whether fecal microbiota transplantation (FMT) can suppress or reverse gastrointestinal carriage of MDROs in hospitalized solid organ transplant recipients with a history of one or…
- Trial name
- FMT (NCT02816437)
- Testing
- OpenBiome Fecal Microbiota Transplantation retention enema
- Sponsor
- University of Miami
Apraxia Speech
Transcranial Magnetic Stimulation (TMS) for Primary Progressive Apraxia of Speech (PPAOS)
The purpose of this study is to assess the influence of transcranial magnetic stimulation (TMS) on speech performance in individuals with primary progressive apraxia of speech.
- Trial name
- NCT03028324
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Miami
Educational Control, Resistance Training
High Speed Circuit Training and Cognition
The purpose of this research study is to see if a weight training program can make a positive change in participant fitness as measured by the ability to use oxygen and help the participant remember things.
- Trial name
- NCT04022707
- Testing
- High-speed circuit resistance training, Educational control
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Miami
Photoaging
Combination Versus Laser Treatment Only
Our objective is to determine the effects of (1) basic skin care regimen + "active" (Lytera 2.0) vs. (2) basic skin care regimen only, both groups combined with laser, on the appearance of skin tone and photo-aging on the face.
- Trial name
- NCT03661697
- Testing
- Laser Therapy, Basic Skin Care Regimen, Lytera
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cerebrospinal Fluid Leak
Acetazolamide to Prevent Post Operative CSF Leak
The purpose of this research is to test the use of Acetazolamide in preventing post-operative cerebrospinal fluid leak in patients having endoscopic skull base surgery (it is a surgery performed through the nose and sinus).
- Trial name
- NCT02902133
- Testing
- Acetazolamide
- Sponsor
- University of Miami
Endometrial Cancer
Sentinel Lymph Node Dissection (SLND) in Patients With Apparent Early Stage Endometrial Cancer
The investigators hypothesize that SLND (unlike lymphadenectomy) decreases complications such as hemorrhage, lower extremity lymphedema and lymphocyst formation while enhancing quality of life in EC patients with low risk for…
- Trial name
- NCT02834988
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Miami
Obesity, Metabolic Syndrome
Effects of Leptin Replacement in Children
To assess the endocrine and immune effects of leptin replacement in leptin-deficient children, from a consanguineous family. The hypothesis is that leptin replacement will have significant effects on endocrine function.
- Conditions
- Obesity, Metabolic Syndrome, Diabetes
- Trial name
- NCT00659828
- Testing
- Recombinant methionyl human leptin
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Miami
Obesity, Metabolic Syndrome
Effects of Human Leptin Replacement
This study will test the hypothesis that leptin contributes to the regulation of the dynamics of human endocrine function.
- Conditions
- Obesity, Metabolic Syndrome, Diabetes
- Trial name
- NCT00657605
- Testing
- Recombinant methionyl human leptin
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Miami
Uveal Melanoma
Vorinostat in Patients With Class 2 High Risk Uveal Melanoma
This proof-of-concept study will evaluate the ability of vorinostat to induce the transformation of Class 2 uveal melanoma cells into a cell phenotype that resembles normal melanocytes.
- Trial name
- NCT03022565
- Testing
- Vorinostat
- Sponsor
- University of Miami
Cleaning Product Causing Toxic Effect
AvenovaTM as a Sterile Skin Preparation Agent
Aim 1: To determine in vivo capability of AvenovaTM against common cutaneous microbial biome on human skin Aim 2: To compare to povidone-iodine 5% solution, 4% chlorhexidine and isopropyl alcohol against AvenovaTM as a sterile…
- Trial name
- NCT02990013
- Testing
- Avenova, Povidone-iodine 5% solution, 4% chlorhexidine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Miami
Head and Neck Cancer, Lung Cancer
DMH-Based Plan Evaluation and Inverse Optimization in Radiotherapy
The hypotheses of the study are as follows: Mass-based inverse optimization in radiotherapy treatment planning will result in a reduction of normal tissue and organs at risk (OAR) doses for desired prescription therapeutic doses…
- Conditions
- Head and Neck Cancer, Lung Cancer, Prostate Cancer
- Trial name
- NCT02663817
- Testing
- CT Scan
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Miami
Emotional Adjustment
MCRF Clinical Pilot Study
The purpose of this study is to see if music can help children practice how to manage their emotions.
- Trial name
- NCT03991585
- Testing
- Musical Contour Regulation Facilitation (MCRF)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Miami
Healthy Lifetime Non-smokers
Evaluation of Acute and Subacute Effects of Nicotine Free Electronic Cigarette(NCFE) Vapors
This aim will examine the acute and subacute exposures to electronic cigarette (EC) vapor generated from e-liquids without nicotine (NFEC) on life-time non smokers subjects by measuring changes in nasal ion transport and TGF-β…
- Trial name
- NCT02585791
- Testing
- Propylene Glycol, vegetable glycerin, PG+VG
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Miami
Orthopedic Disorders, Injury of Anterior Cruciate Ligament
Injection Pressure & Adductor Canal Block
This is a prospective, randomized, single-blinded human clinical trial that will examine how injection pressure influences the spread of a given volume of injectate in the adductor canal, during adductor canal nerve block.
- Trial name
- NCT02563990
- Testing
- High Pressure Injection, Low Pressure Injection
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Miami
Overweight and Obesity
Exercise and Nutrition on Obese Microbiome
The purpose of this study is to examine the effects nine weeks of intense exercise training will have on weight, inflammation, and intestinal bacteria composition of overweight and obese adults.
- Trial name
- NCT04138303
- Testing
- Exercise Protocol, Calorie-Restrictive Low Carbohydrate Diet (CR-LC), Ancestral Diet (AD)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Miami
HIV
Striving Towards EmPowerment and Medication Adherence (STEP-AD)
Striving Towards Empowerment and Medication Adherence (STEP-AD) is a research study aimed at developing an intervention for Black women living with HIV to address psychosocial factors (i.e.
- Trial name
- STEP-AD (NCT02764853)
- Testing
- Experimental Intervention (STEP-AD), Enhanced Treatment as Usual (E-TAU)
- Where
- 2 sites in United States
- Volunteers
- 184 people
- Sponsor
- University of Miami
Ischemic Stroke
Albumin in Acute Ischemic Stroke Trial
The goal of the trial is to determine whether human albumin, administered within 5 hours of symptom onset, improves the 3-month outcome of subjects with acute ischemic stroke.
- Trial name
- ALIAS (NCT00235495)
- Testing
- Albumin, Saline
- Where
- 89 sites in United States, Canada and 2 more
- Volunteers
- 841 people
- Sponsor
- University of Miami
Phenylketonuria
Kuvan Therapy in Phenylketonuria (PKU): The Effect of Blood Phenylalanine Concentration on Kuvan Response
The investigators will investigate the effect of blood phenylalanine on Kuvan responsiveness in the same patients with PKU when their blood phenylalanine concentrations are altered by diet.
- Trial name
- NCT00841100
- Testing
- Kuvan, Diet
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Miami
Venous Thromboembolism, Thromboprophylaxis
Aspirin and Enoxaparin for VTE in Trauma
The purpose of this study is to determine if the addition of antiplatelet therapy (i.e. aspirin) to low-molecular-weight-heparin (i.e.
- Conditions
- Venous Thromboembolism, Thromboprophylaxis, Trauma
- Trial name
- NCT02396732
- Testing
- Aspirin, Enoxaparin
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Miami