Clinical trials: sponsored by University of Miami
Depression
Magnesium Sulfate Versus 5% Dextrose With Treatment Resistant Depression
The proposed study is a 1-week, randomized, double-blind, placebo-controlled, trial to evaluate the efficacy of an IV infusion of magnesium sulfate on symptoms of treatment resistant mild and moderate depression in 20 males and…
- Trial name
- NCT01597167
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Miami
Cardiovascular Diseases, Heart Diseases
Psychophysiology of Cardiovascular Reactivity
To determine why Black Americans have a higher prevalence of hypertension than whites by examining the interactions of psychosocial stressors and suppressed hostility with genetic or constitutional factors.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension
- Trial name
- NCT00005192
- Sponsor
- University of Miami
Marginal Zone Lymphoma
Yttrium Y 90 Ibritumomab Tiuxetan and Rituximab in Treating Patients With Previously Untreated Marginal Zone Lymphoma
Zevalin may be an effective therapy for newly diagnosed marginal zone lymphoma (MZL).
- Trial name
- NCT00453102
- Testing
- Rituximab, Ibritumomab Tiuxetan
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Leukemia, Myelodysplasia
Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients With High Risk Leukemia and Myelodysplasia
Unrelated Cord Blood (UCB) transplant in children is a viable stem cell transplant modality for patients with leukemia and myelodysplasia.
- Conditions
- Leukemia, Myelodysplasia, Acute Lymphocytic Leukemia, Acute Myelogenous Leukemia
- Trial name
- NCT02007863
- Testing
- Umbilical Cord Blood Transfusion, Fludarabine, Busulfan
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- University of Miami
Schizophrenia
Culturally Based Family Therapy for Improving Treatment Outcome for People With Schizophrenia
This study will evaluate the effectiveness of a culturally based family therapy intervention in improving treatment outcome in people with schizophrenia.
- Trial name
- NCT00356317
- Testing
- Culturally informed therapy for schizophrenia (CIT-S), Psychoeducation treatment as usual
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Miami
Premature Birth
Three Interacting Single Nucleotide Polymorphisms (SNPs) and the Risk of Preterm Birth in Black Families
A multilocus interaction of three pro-inflammatory cytokine single nucleotide polymorphisms (SNPs), -3448 Tumor Necrosis Factor-α, -7227 Interleukin 6, and 33314 Interleukin 6R was reported by Menon and associates in 2006.
- Trial name
- NCT00675753
- Testing
- Blood spot specimens will be drawn
- Where
- 2 sites in United States
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- University of Miami
Depression, Social Anxiety
Coping With Adolescent Peer Victimization and Reducing Anxious/Depressed Symptoms
Among adolescents, SAD and depression are prevalent, highly comorbid, and can be chronic and impairing. Interpersonal peer victimization (IPV) is a key stressor that contributes to both social anxiety and depression in…
- Trial name
- NCT02011438
- Testing
- UTalk
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Miami
Substance Use Disorders, Risk Behavior
Culturally Informed Family Based Treatment of Adolescents: A Randomized Trial
This Stage II randomized trial tests Culturally Informed \& Flexible Family Based Treatment for Adolescents (CIFFTA) developed as part of a Stage I treatment development effort and yielding promising preliminary findings.
- Conditions
- Substance Use Disorders, Risk Behavior, Psychiatric Disorders, Family Dysfunction
- Trial name
- CIFFTA (NCT01823250)
- Testing
- Family Therapy based on Structural Family Therapy, Group Therapy, Psychoeducational Sessions
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- University of Miami
Stem Cell Transplantation, Ventricular Dysfunction, Left
The Transendocardial Autologous Cells (hMSC or hBMC) in Ischemic Heart Failure Trial (TAC-HFT)
The technique of transplanting progenitor cells into a region of damaged myocardium, termed cellular cardiomyoplasty, is a potentially new therapeutic modality designed to replace or repair necrotic, scarred, or dysfunctional…
- Trial name
- TAC-HFT (NCT00768066)
- Testing
- Autologous human mesenchymal cells (hMSCs), Autologous human bone marrow cells (hBMCs)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Miami
HIV, Acquired Immunodeficiency Syndrome
Evaluating an Exercise Program to Reduce Cardiovascular Risk Factors in Children Infected With HIV
People infected with HIV are now living longer lives because of the use of highly active antiretroviral therapy (HAART). However, HAART medications have been shown to increase the risk of cardiovascular disease and metabolic…
- Conditions
- HIV, Acquired Immunodeficiency Syndrome, Cardiovascular Diseases
- Trial name
- NCT00908284
- Testing
- Exercise Program, Control Group
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Miami
Glaucoma
Tube Versus Trabeculectomy (TVT) Study
The purpose of the Tube Versus Trabeculectomy (TVT) Study is to compare the safety and efficacy of nonvalved tube shunt surgery to trabeculectomy with mitomycin C in patients with previous ocular surgery.
- Trial name
- NCT00306852
- Testing
- Baerveldt implant, Trabeculectomy with mitomycin C
- Where
- 17 sites in United States, United Kingdom
- Volunteers
- 212 people
- Sponsor
- University of Miami
Cholestasis, Prematurity
Prevention of Parenteral Nutrition-Associated Cholestasis With Cyclic Parenteral Nutrition in Infants
Hypothesis to be Tested: Since the first description of intravenous alimentation over half a century ago, parenteral nutrition (PN) has become a common nutritional intervention for conditions characterized by inability to…
- Conditions
- Cholestasis, Prematurity, Gastroschisis, Intestinal Atresia
- Trial name
- NCT01062815
- Testing
- Parenteral Nutrition
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Miami
Spinal Cord Injury
Skilled Motor Training and tDCS to Improve Leg Function After Spinal Cord Injury
The study investigates the effect of using transcranial direct current stimulation (tDCS) and skilled stepping training versus skilled stepping training with sham-tDCS in improving ankle and leg motor control in persons with…
- Trial name
- SLT (NCT01962675)
- Testing
- Transcranial direct current stimulation + step training
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Miami
Transplant; Failure, Kidney
XM-One Study for Living Donor Program
Donor-Specific Antibody (DSA) (HLA) levels and non-HLA antibody levels in recipients prior to living kidney transplantation and randomize these individuals into a desensitization protocol in order to evaluate shifts that can…
- Trial name
- NCT01679184
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Miami
Lymphoma
R-MACLO-IVAM and Thalidomide in Untreated Mantle Cell Lymphoma
RATIONALE: To evaluate the efficacy of a new high intensity chemotherapy regimen with thalidomide maintenance in patients with newly diagnosed mantle cell lymphoma PURPOSE: This phase II trial is studying how well giving…
- Trial name
- NCT00450801
- Testing
- Rituximab, Cyclophosphamide, Cytarabine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Miami
Breast Cancer
Facilitating Adjustment in Low Income Black Women With Breast Cancer
The main goal of the proposed study is to test whether a successful stress management intervention can be effectively implemented in natural settings in the community and will be acceptable to a community dwelling, low income…
- Trial name
- NCT02272335
- Testing
- Group Sessions
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- University of Miami
Substance-Related Disorders
Rapid HIV Testing and Counseling in Drug Abuse Treatment
This is a randomized controlled clinical trial in which adults receiving drug abuse treatment will be recruited to participate in a multi-center HIV testing and counseling study.
- Trial name
- NCT00809445
- Testing
- On-site HIV rapid test and brief, prevention counseling, On- site HIV rapid test & information, Referral for off-site HIV testing
- Where
- 12 sites in United States
- Volunteers
- 1,281 people
- Sponsor
- University of Miami
HIV Infections
Emotional Disclosure in HIV
The specific objective of this study are to examine whether or not a treatment aimed at emotional disclosure may have beneficial psychological, health and immune effects for HIV infected individuals.
- Trial name
- NCT00067704
- Testing
- Trauma writing, Writing about daily events
- Where
- United States
- Volunteers
- 283 people
- Sponsor
- University of Miami
Diabetic Peripheral Neuropathy
Laser Therapy for Diabetic Peripheral Neuropathic Pain
The proposed study is a randomized, double-blinded clinical trial to evaluate the efficacy of a course of laser therapy on peripheral neuropathic pain in persons with diabetes.
- Trial name
- NCT02328911
- Testing
- Laser treatment
- Where
- United States
- Sponsor
- University of Miami
Cancer Survivor, Pediatric Cancer
Vascular Endothelial Inflammation and Dysfunction in Pediatric Long-term Cancer Survivors
Survivors of childhood cancer have an increased risk of death from cardiovascular disease due to both the therapies they received while undergoing treatment and diet and lifestyle factors.
- Trial name
- NCT02032121
- Testing
- Blood specimen, Echocardiography
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Miami