Clinical trials: sponsored by University of Miami
Substance Use, Delinquency
Preventing Adolescents From Entering the Juvenile Justice System
This randomized controlled study tests an innovative juvenile diversion model that integrates evidence-based family therapy.Immediate and longer term effects of the family intervention will be compared to Services As Usual with…
- Trial name
- CCP (NCT02147743)
- Testing
- CCP+MDFT, CCP+SAU
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami
Family Member
Everycell's Effect on DNA Damage, Inflammation, and Stress
The investigators are conducting this research because they want to determine if a dietary supplement, called Everycell™, has an effect on the functioning of the study participants' cells.
- Trial name
- NCT02032693
- Testing
- Everycell™
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Miami
Substance Use, Delinquency
Juvenile Detention to Community Life
The fundamental objective of the proposed study is to develop and test an innovative two-stage, cross-systems family-based intervention for substance abusing juvenile offenders.
- Conditions
- Substance Use, Delinquency, Risk for HIV Infection
- Trial name
- DTC (NCT01910324)
- Testing
- Multidimensional Family Therapy Cross-Systems, Enhanced Services as Usual
- Where
- 5 sites in United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- University of Miami
Deep Vein Thrombosis
Coagulation Changes in Trauma Patients
Hypothesis to be tested: placement of a central venous catheter will induce a systemic hypercoagulable state. To determine this, the investigators will measure thromboelastography (TEG), PT(prothrombin time), PTT (partial…
- Trial name
- NCT00795743
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
HIV
Immunogenicity of Inactivated Swine H1N1 Vaccine In HIV Infected Children - The Miami Cohort Study
Immunosuppressed patients are at increased risk for complications of influenza infection, including secondary pneumonia and are recommended for annual influenza vaccination.
- Trial name
- NCT02031874
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Miami
Hypertrichosis
Eyelash Growth From Application of Bimatoprost in Gel Suspension to the Base of the Eyelashes
Objective: To determine if Lumigan (bimatoprost) causes increased lash length when used in gel suspension applied to the base of the eyelashes.
- Trial name
- NCT00773136
- Testing
- Bimatoprost Suspension
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Miami
Premature Birth
Preterm Infants' Weight Gain Following Massage Therapy
The specific aims of this study are: 1) to replicate the data that following ten days of massage therapy, preterm infants show greater daily weight gain and are discharged from the hospital earlier than the controls, thus…
- Trial name
- NCT00029198
- Testing
- massage
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- University of Miami
Primary Biliary Cirrhosis
Fenofibrate in Combination With Ursodeoxycholic Acid (UDCA) in Primary Biliary Cirrhosis
The purpose of this study is to determine if the combination of ursodeoxycholic acid (UDCA) and fenofibrate is more effective than UDCA alone in the treatment of primary biliary cirrhosis.
- Trial name
- NCT01141296
- Testing
- fenofibrate
- Where
- 2 sites in United States
- Sponsor
- University of Miami
Overweight and Obesity
IgG-mediated Food Test for Weight Loss
This study assessed the effect of an IgG-mediated food sensitivity test in combination with a food elimination diet on body composition and secondary outcomes in people who were overweight.
- Trial name
- NCT01592071
- Testing
- Replace reactive foods with non-reactive foods
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami
Glaucoma
Relationship Between Eye Pressure and Ganglion Cell Function in Eyes Receiving Latanoprost Versus Placebo
The purpose of this investigation is to evaluate the relationship between IOP fluctuation, RGC dysfunction, and optic nerve and retinal nerve fiber layer (RNFL) thickness changes in patients with glaucoma and ocular hypertension…
- Trial name
- NCT01042665
- Testing
- latanoprost 0.005%
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Miami
HIV Infections
Long-term Effects of Highly Active Anti-Retroviral Therapy on HIV-Infected Children
This study will use the NIH-sponsored Women and Infants Transmission Study (WITS) and the Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection (P2C2) HIV-infected pediatric cohorts to…
- Trial name
- NCT00260806
- Where
- 9 sites in United States, Puerto Rico
- Volunteers
- 71 people
- Sponsor
- University of Miami
Cardiovascular Diseases, Heart Diseases
Effects of Highly Active Anti-Retroviral Therapy on Cardiovascular Health in Infants of HIV-Infected Mothers
This study will determine the impact of highly active antiretroviral therapy (HAART) on the developing cardiovascular system, the evolution of HAART-associated cardiovascular changes over time, and the association between…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis, HIV Infections
- Trial name
- CHAART-1 (NCT00253682)
- Where
- 5 sites in United States
- Volunteers
- 167 people
- Sponsor
- University of Miami
Substance Use, Unsafe Sexual Behavior
Familias Unidas: Preventing Drug Abuse and HIV in Hispanic First Offenders
The main goal of the proposed study is to evaluate the efficacy of Familias Unidas (United Families), a family-based, ecodevelopmental intervention found to be previously efficacious in preventing and reducing behavior problems…
- Trial name
- NCT01257022
- Testing
- Familias Unidas
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- University of Miami
Patent Ductus Arteriosus
Timing of PDA Closure and Respiratory Outcome in Premature Infants
The investigators propose the present study with the following aims: to determine whether early patent ductus arteriosus (PDA) treatment with ibuprofen treatment at the onset of clinical symptoms is superior to late ibuprofen…
- Trial name
- NCT00802685
- Testing
- Early ibuprofen
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Miami
HIV, Pregnancy
Promoting Male Involvement to Improve Prevention of Mother to Child Transmission (PMTCT) Uptake and Reduce Antenatal Infection
This study will evaluate the impact of combining two evidence-based interventions: a couples risk reduction intervention with an evidence based medication adherence intervention designed to enhance male participation in…
- Trial name
- NCT01448512
- Testing
- PartnerPlus Intervention, Usual Care
- Where
- South Africa
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- University of Miami
Spinal Cord Injury
Improving Hand and Arm Function After Spinal Cord Injury (SCI)
The long-term goal of this project is to develop rehabilitation strategies that facilitate optimal restoration of skilled hand use in individuals with spinal cord injury (SCI).
- Trial name
- NCT01143597
- Testing
- Arm and hand training
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Miami
Dry Eye
Diurnal Variation of Tear Meniscus and Tear Osmolarity
This study is to determine the diurnal variation of tear meniscus and tear osmolarity in normal subjects and dry eye patients.
- Trial name
- NCT01206244
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Miami
Substance Abuse, Families
Family-Based Drug Services for Young Disaster Victims
This protocol seizes this rare scientific opportunity to test an integrative family based model to address youths' coexisting substance abuse and trauma in the wake of Hurricane Katrina.
- Conditions
- Substance Abuse, Families, Trauma
- Trial name
- Katrina (NCT01859000)
- Testing
- Multidimensional Family Therapy, Group CBT
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Miami
Trauma
Optimal Fluid Resuscitation for Trauma Patients
The purpose of this study is to determine if the overall fluid requirements for the first 24 hours after admission will be reduced with Hextend versus a standard of care crystalloid resuscitation fluid.
- Trial name
- NCT00527098
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- University of Miami
Metabolic Syndrome
Biobehavioral Bases & Management of Metabolic Syndrome (CHARMS)
The metabolic syndrome is increasingly being recognized as a major threat to good health - especially cardiovascular health - and its frequency appears to be increasing in relation to the current epidemic of obesity.
- Trial name
- CHARMS (NCT01741298)
- Testing
- CHARMS
- Volunteers
- 112 people
- Sponsor
- University of Miami