Clinical trials: sponsored by University of Minnesota
Obesity, Childhood, Physical Activity
New Ulm at HOME (Healthy Offerings Via the Mealtime Environment), NU-HOME
The goal of the proposed project is to see if an innovative family-based intervention can reduce childhood obesity by actively engaging the whole family in promoting healthy behaviors in the home.
- Conditions
- Obesity, Childhood, Physical Activity, Food Intake, Rural Health
- Trial name
- NU-HOME (NCT02973815)
- Testing
- NU-HOME Intervention
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Type 2 Diabetes Mellitus
The Long-term Effects of an Intensive Lifestyle Intervention for Type 2 Diabetes on Medicare Outcomes
This study investigates whether an intensive lifestyle intervention for type 2 diabetes had long-term effects on Medicare enrollment, health care use, and health care spending.
- Trial name
- NCT03952728
- Testing
- Intensive lifestyle intervention, Diabetes support and education
- Volunteers
- 2,796 people
- Sponsor
- University of Minnesota
Tobacco Smoking
Methods Project 4: Clinical Trial - Amended
Cigarette smokers will be randomized to E-cigarette, Nicotine Gum or Lozenge, or Control Group. Participants will enter a 1 week sampling phase.
- Trial name
- COMET (NCT03111537)
- Testing
- Cigarettes, E-Cigarette, Nicotine Gum or Lozenge
- Where
- 3 sites in United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity, Diet Modification
Metabolic Impact of Time Restricted Feeding
The investigators are interested in how time-restricted feeding will impact weight, sleep duration and efficacy, and activity levels in obese adults.
- Trial name
- NCT03129581
- Testing
- Dietary Counseling
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
SRP, Minocycline HCl Microspheres
Systemic Markers of Inflammation: 9- and 12-Month Follow-Up Post Non-Surgical Periodontal Therapy
The primary goal of this study is to determine the amount of three systemic markers of inflammation: 1) Hemoglobin A1c (Hgb A1c, 2) High Sensitivity C-Reactive Protein (hsCRP), and 3) Haptoglobin (Hp) at 9 and 12 month follow-up…
- Conditions
- SRP, Minocycline HCl Microspheres, Biomarkers
- Trial name
- NCT04312542
- Testing
- Measurement of Biomarkers
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Minnesota
Pregnancy
Use of an Occlusal Support Device During the Second Stage of Labor
The primary objectives of this study are to determine if the use of an Occlusal Support Device (OSD)(Mouthguard) can reduce the duration and intensity of the second stage of labor, reduce the incidence of labor complications…
- Trial name
- NCT02807493
- Testing
- Occlusal Support Device, Control
- Where
- United States
- Volunteers
- 347 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Anorexia Nervosa
Neural Correlates of Reward and Symptom Expression in Anorexia Nervosa
The objective of this study is to identify the patterns of brain activity in reward circuitry that promote symptoms of anorexia nervosa.
- Trial name
- NCT03275545
- Testing
- No intervention
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Stroke, Hemiparesis
Perinatal Stroke: Understanding Brain Reorganization
The incidence of perinatal stroke is relatively common, as high as 1 in 2,300 births, but little is known about the resulting changes in the brain that eventually manifest as cerebral palsy (CP).
- Trial name
- NCT02743728
- Testing
- Magnetic Resonance Imaging, Transcranial Magnetic Stimulation, General Movement Assessment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Intervention, Waitlist Control
Online Program for Coaching Girls: Coaching HER
Despite the numerous physical and psychological benefits of taking part in sport, studies consistently show that only 15% of adolescent girls globally meet the recommended daily exercise guidelines (Guthold et al., 2018).
- Trial name
- NCT05500781
- Testing
- Coaching HER
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Anesthesia, Surgery
Post-operative Sore Throat and Gum Chewing
The purpose of this study is to determine if chewing gum immediately prior to transport to the operating room reduces the severity of post-operative sore throat in patients who have an LMA (laryngeal mask airway) placed for…
- Trial name
- NCT04859101
- Testing
- Gum, Control
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Generalized Anxiety Disorder, Panic Disorder
Adapting an Effective CBT for Comorbidity to a Computer-Delivered Format
Up to one-half of those in treatment for alcohol use disorder (AUD) has a co-occurring anxiety disorder ("comorbidity"), a condition that marks a high degree of treatment resistance, severity and relapse risk in AUD treatment…
- Conditions
- Generalized Anxiety Disorder, Panic Disorder, Social Anxiety, Alcohol Use Disorder
- Trial name
- NCT03300232
- Testing
- Computer-based VC-CBT
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Minnesota
Epilepsy, Complex Partial
Neural Correlates of Cognition and Mood
The overall objective of this study is to determine the neural correlates of cognition and mood. This study represents the first preliminary study to begin investigating cognitive and emotional states in patients who have…
- Trial name
- NCT04573569
- Testing
- Behavioral testing
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Minnesota
Mal de Debarquement Syndrome
Transcranial Magnetic Stimulation for Mal de Debarquement Syndrome
The goal of this study is to determine whether external neuromodulation using repetitive transcranial magnetic stimulation (rTMS) can reduce the perception of self-motion that is experienced by individuals with mal de…
- Trial name
- NCT02470377
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Minnesota
Lumbar Disc Herniation, Degenerative Disc Disease
Peri-Incisional Drug Injection in Lumbar Spine Surgery
This is a randomized prospective study that will compare the use of narcotics in a control group of non-injected patients with a treatment arm of patients injected intra-operatively with a ropivacaine, morphine, and epinephrine…
- Conditions
- Lumbar Disc Herniation, Degenerative Disc Disease, Spondylolisthesis
- Trial name
- NCT03513445
- Testing
- Morphine, Epinephrine, naropin
- Where
- United States
- Sponsor
- University of Minnesota
COVID, COVID19
International SARS-CoV-2 (COVID-19) Infection Observational Study
The general aim of this study is to estimate the rate of disease progression for adults testing positive for SARS-CoV-2. The primary endpoint for this study and the basis for sample size is hospitalization or death during the 28…
- Conditions
- COVID, COVID19, SARS-CoV 2, Dyspnea
- Trial name
- ICOS (NCT04385251)
- Testing
- Data Collection
- Where
- 4 sites in United States, Argentina and 2 more
- Volunteers
- 11,973 people
- Sponsor
- University of Minnesota
Covid19, SARS-CoV Infection
Epidemiologic Assessment of SARS-CoV-2 (COVID-19) Prevalence in Minnesota
The purpose of this epidemiologic study is to estimate the prevalence and incidence of anti-SARS-CoV-2 antibodies in at-risk, exposed, affected populations.
- Conditions
- Covid19, SARS-CoV Infection, SARS-CoV-2, Corona Virus Infection
- Trial name
- NCT04473183
- Testing
- Specimen Collection, Surveys
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Sub-cortical Stimulation
Ultrasound in Deep Brain Stimulation
It is the purpose of this proposal to apply tFUS to the ventral posterior lateral (VPL) nucleus of the thalamus in humans.
- Trial name
- NCT02382965
- Testing
- transcranial focused ultrasound
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Pre-Eclampsia
Placental Volume, Flow, and Vascularity Study
The purpose of this preliminary study is to implement an automated and standardized computer-based method that accurately measures placental volume, blood flow, and vascularity.
- Trial name
- NCT04900207
- Where
- United States
- Volunteers
- 440 people
- Sponsor
- University of Minnesota
Scoliosis, Adolescent Idiopathic Scoliosis
Min Implants Max Outcomes Clinical Trial
Objectives Primary objective: Determine if there is a clinically significant difference in percent Cobb curve correction in a low- vs. high-implant density cohort through a prospective randomized controlled trial.
- Trial name
- MIMOCT (NCT01792609)
- Testing
- Maximum Number of Screws, Minimum Number of Screws
- Where
- 14 sites in United States, Canada
- Volunteers
- 200 people
- Sponsor
- University of Minnesota
Alzheimer Disease, Dementia
The Residential Care Transition Module
Emerging research on family caregiving and institutionalization has emphasized that families do not disengage from care responsibilities following a relative's admission to residential long-term care settings.
- Trial name
- RCTM (NCT02915939)
- Testing
- The Residential Care Transition Module
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
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