Clinical trials: sponsored by University of Rochester
Diabetes Mellitus, Type 1
Study of Calcium Metabolism in Teenage Girls With Type 1 Diabetes
The proposed pilot study will enroll 33 adolescent females with type 1 diabetes for the assessment of whole body calcium metabolism using dual stable calcium isotopes.
- Trial name
- NCT03156179
- Testing
- calcium isotope analysis
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Rochester
Overactive Bladder
Pilot Study: Is Overactive Bladder Caused by Subacute Urinary Tract Infections?
The purpose of this study is to look for evidence of bacteria in the urine or bladder of people with overactive bladder. Because you do not have overactive bladder, your participation in this study will be used as a comparison to…
- Trial name
- NCT00714792
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Urinary Incontinence
Assessment of Two Postoperative Techniques Used to Predict Voiding Efficiency After Gynecologic Surgery
After gynecologic surgery, it may be difficult to void (urinate). This problem is usually short-term with normal function returning within a few days to a few weeks.
- Trial name
- NCT00392210
- Testing
- Voiding Trial
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Stress Disorders, Post-Traumatic, Depression
Managing Sleep Symptoms and Modifying Mechanisms of Traumatic Stress
The primary purpose of this study is to test whether and how cognitive-behavioral therapy for insomnia (CBTi), a well-supported and highly effective insomnia treatment, may directly improve Posttraumatic Stress Disorder (PTSD)…
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Sleep
- Trial name
- NCT01743339
- Testing
- Cognitive Behavioral Therapy, Control
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Rochester
Prostate Cancer, Urinary Tract Infection
Antibiotic Prophylaxis for Urinary Catheter Removal After Radical Prostatectomy
The aim of this study is to determine whether antibiotics prophylaxis at the time of urinary catheter removal decreases the number of symptomatic urinary tract infections in patients after radical prostatectomy.
- Conditions
- Prostate Cancer, Urinary Tract Infection, Clostridium Difficile
- Trial name
- Abx (NCT02247960)
- Testing
- Ciprofloxacin
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- University of Rochester
Leukemia, Myeloid, Acute, Leukemia, Lymphoblastic, Acute
Use of Saline-Washed Platelet and Red Cell Transfusions in Adult Acute Leukemia
The purpose of this study is to determine whether a novel standard of care protocol, washing red cell and platelet transfusions for younger patients with acute leukemia, has yielded improved clinical outcomes at Strong Memorial…
- Trial name
- NCT01976442
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Rochester
Age-associated Memory Impairment, Alteration of Cognitive Function
Hormones and Cognition in the Menopausal Transition
The purpose of this study is to determine if the menopausal transition is associated with subjective and objective cognitive declines that ameliorate in menopause.
- Trial name
- NCT01429103
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Psychotic Disorders
Forensic Assertive Community Treatment: An Emerging Model of Service Delivery
The FACT model (ACT + legal leverage in the form of judicial monitoring) will be compared to enhanced outpatient treatment (close outpatient follow-up without judicial monitoring).
- Trial name
- FACT (NCT01313052)
- Testing
- Forensic Assertive Community Treatment (FACT), Enhanced Treatment as Usual
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Rochester
Elevated Risk of Cardiovascular Disease, Tobacco Dependence
Virtual Clinician Research Tool
The Virtual Clinician Research Tool (VCRT) will use a virtual format to present our National Cholesterol Education Program (Brown, 2004) and the Tobacco Use and Dependence Treatment Clinical Guideline (Fiore et al., 2008)…
- Trial name
- VCRT (NCT01408758)
- Testing
- Virtual Clinician Research Tool (VCRT), No VCRT, only physician counseling at visits
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of Rochester
Autism, Enuresis
Development of a Manualized Wireless Moisture Pager Intervention for Teaching Toileting in Children With Autism
This pilot study is designed to investigate the feasibility of comparing a standard behavioral intervention and an innovative intervention that incorporates the use of a wireless moisture alarm in training children with autism…
- Conditions
- Autism, Enuresis, Incontinence
- Trial name
- NCT01978210
- Testing
- Wireless Moisture Pager (WMP)
- Where
- 3 sites in United States
- Volunteers
- 31 people
- Sponsor
- University of Rochester
Parkinson Disease
Remote Access to Care, Everywhere, for Parkinson Disease
The primary objective of this study is to evaluate the feasibility, efficacy and the value of providing care to individuals with Parkinson disease directly into their homes. The specific aims are: 1.
- Trial name
- RACE-PD (NCT02144220)
- Testing
- Virtual care visit
- Where
- 3 sites in United States
- Volunteers
- 277 people
- Sponsor
- University of Rochester
Insomnia, Fatigue
Cognitive Behavioral Therapy +/- Armodafinil for Insomnia and Fatigue Following Chemotherapy
This is a four-arm, randomized, controlled, clinical trial examining the efficacy of of cognitive behavioral therapy (CBT)-I and armodafinil in reducing insomnia in 226 female breast cancer patients who report sleep disturbances…
- Conditions
- Insomnia, Fatigue, Breast Cancer
- Trial name
- NCT01091974
- Testing
- armodafinil, CBT-I
- Where
- 2 sites in United States
- Volunteers
- 138 people
- Sponsor
- University of Rochester
Parkinson Disease
Connect.Parkinson: Connecting Individuals With Parkinson Disease to Specialists in Their Homes
Connect.Parkinson is a randomized comparative effectiveness study, comparing usual care enhanced with educational materials to usual care, educational materials, and the delivery of specialty care via telemedicine into patient's…
- Trial name
- NCT02038959
- Testing
- Virtual Visits
- Where
- 20 sites in United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Suicide Prevention
Effectiveness Trial of Youth Suicide Prevention Delivered by Teen Peer Leaders
The purpose of this study is to evaluate the impact of the school-based Sources of Strength program in reducing suicidal behaviors in the population of high school students and determine how the program works (mechanisms of…
- Trial name
- NCT02043093
- Testing
- Sources of Strength
- Where
- United States
- Volunteers
- 17,603 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Influenza
Effect of Age and Prior Immunity to Response to Seasonal Influenza Vaccines in Children
A total of 88 children between 2 and 9 years of age will be randomized to receive a two dose schedule of either licensed live attenuated trivalent seasonal influenza vaccine (LAIV) or licensed inactivated seasonal influenza…
- Trial name
- NCT01246999
- Testing
- Live attenuated Influenza vaccine, Trivalent Influenza Vaccine, TIV followed by LAIV
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Adult Diffuse Large B-Cell Lymphoma, Mantle Cell Lymphoma Recurrent
A Phase II Study of Doxycycline in Relapsed NHL
The purpose of this study is to determine whether doxycycline is effective in the treatment of relapsed Non Hodgkin Lymphomas (NHL).
- Conditions
- Adult Diffuse Large B-Cell Lymphoma, Mantle Cell Lymphoma Recurrent, Lymphoma, Follicular, Marginal Zone B-Cell Lymphoma
- Trial name
- NCT02086591
- Testing
- Doxycycline
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Rochester
Substance Use, Psychopathy
The Impact of Psychopathic Traits on the Efficacy of a Substance Use Intervention
Substance use among criminal offenders constitutes a major public health problem and is tied to negative consequences for offenders, their families, and their communities.
- Trial name
- NCT01532934
- Testing
- motivational enhancement therapy, standard care
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Rochester
Chronic Myeloproliferative Disorders, Graft Versus Host Disease
Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing a Donor Umbilical Cord Blood Transplant for Hematologic Cancer
RATIONALE: Giving low doses of chemotherapy, such as fludarabine and cyclophosphamide, and radiation therapy before a donor umbilical cord blood stem cell transplant helps stop the growth of cancer cells.
- Conditions
- Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma
- Trial name
- NCT00255684
- Testing
- graft-versus-tumor induction therapy, cyclophosphamide, cyclosporine
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Rochester
Stroke
Activated Protein C in Acute Stroke Trial
The purpose of this research study is to determine the safety and learn more about the dose of Activated Protein C (APC) in reducing the damage from stroke.
- Trial name
- APCAST (NCT00533546)
- Testing
- Activated Protein C
- Where
- 9 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Rochester
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
PVI Using Cryoablation Alone in Paroxysmal AF Patients Converted From Persistent AF With Dofetilide
To determine the efficacy of cryoablation alone in patients with paroxysmal atrial fibrillation who have been pretreated with dofetilide and converted from persistent atrial fibrillation.
- Trial name
- ABLATE (NCT01877486)
- Testing
- Ablation
- Where
- United States
- Sponsor
- University of Rochester