Clinical trials: sponsored by University of Toronto
Adiposity, Metabolic Syndrome
Meta-analysis of Low-calorie Sweetened Beverages and Cardiometabolic Outcomes
We propose to conduct a systematic literature review and meta-analysis to assess the association of low-calorie sweetened beverages (LCSBs) on cardiometabolic outcomes in prospective cohort studies.
- Conditions
- Adiposity, Metabolic Syndrome, Type 2 Diabetes, Cardiovascular Diseases
- Trial name
- NCT04245826
- Testing
- Change in LCSBs Intake, Substitute LCSBs for SSBs or Water
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Otitis Media
Antimicrobial Stewardship in Community Pharmacy
Acute otitis media (AOM) is the most common indication for antibiotics for Canadian paediatric patients. As the gatekeepers of safe and effective prescription pharmacotherapy, community pharmacists are well positioned to…
- Trial name
- NCT04219553
- Testing
- Antimicrobial stewardship, Comparator (no intervention)
- Where
- 2 sites in Canada
- Volunteers
- 188 people
- Sponsor
- University of Toronto
Lupus Erythematosus, Systemic
Contemplation-Based Intervention and Health Outcomes RCT in Lupus Patients
The objective of this study is to test the efficacy of an innovative contemplative-based and caregiver-inclusive intervention can modify pathogenic processes in systemic lupus erythematosus (SLE) compared to a…
- Trial name
- NCT04032496
- Testing
- Contemplative-Based Intervention for People Living with SLE, Health Enhancement Program (HEP)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Parkinson Disease
Flexible vs. Standard Deep Brain Stimulation Programming in Parkinson Disease Patients
Exploring the benefits of the linear lead in deep brain stimulation.
- Trial name
- NCT04116177
- Testing
- Deep brain stimulation
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- University of Toronto
HIV, Sexually Transmitted Diseases
HIV and Sexually Transmitted Infection Prevention Intervention in the Northwest Territories
Indigenous youth are disproportionately represented in new HIV infection rates in Canada. Limited studies have evaluated longitudinal effects of arts-based approaches to HIV prevention with youth.
- Trial name
- NCT02743026
- Testing
- FOXY
- Where
- Canada
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Parkinson Disease
Expanding the Therapeutic Window of Deep Brain Stimulation in Parkinson's Disease by Means of Directional Leads
Exploring directional lead
- Trial name
- NCT04093544
- Testing
- Deep brain stimulation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Toronto
Body Weight, Obesity
Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes
The Nordic Diet is a dietary pattern rich in traditional Nordic foods, including berries, grains, and fatty fish common in northern Europe.
- Conditions
- Body Weight, Obesity, Overweight and Obesity, Obesity, Abdominal
- Trial name
- NCT04094194
- Testing
- Nordic diet
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Stroke
Therapeutic Instrumental Music Performance With Sensory-Enhanced Motor Imagery in Chronic Post-Stroke Rehabilitation
Research has shown that music engages the brain bilaterally throughout cortical and subcortical regions, accessing extended sensorimotor, cognitive and affective networks.
- Trial name
- NCT03246217
- Testing
- Therapeutic Instrumental Music Performance, Therapeutic Performance with Sensory-Enhanced Motor Imagery, Therapeutic Performance with Motor Imagery
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Toronto
Delirium
EEG Phase Synchrony, Sedation and Delirium in the CVICU
EEG phase synchrony and variability has had limited investigation during transition from coma to wakefulness in response to sedation and analgesia.
- Trial name
- SOS (NCT04005196)
- Testing
- EEG
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Toronto
Hypertension, Diet, Healthy
mDASHNa-CC APP to Support a Healthy Diet and Hypertension Control for Chinese Canadian Seniors
The aim of this proposed study is to translate the Dietary Approach to Stop Hypertension with Sodium (Na) Reduction for Chinese Canadian (DASHNa-CC), a classroom-based antihypertensive dietary educational intervention, to an…
- Trial name
- NCT03988894
- Testing
- mDASHNa App
- Volunteers
- 60 people
- Sponsor
- University of Toronto
Immunisation Anxiety Related Reaction
Feasibility of Implementation of CARD for School-Based Immunizations
A multi-faceted knowledge translation intervention - The CARD (C-Comfort, A-Ask, R-Relax, D-Distract) System - was developed to improve the vaccination experience of students at school.
- Trial name
- NCT03948633
- Testing
- Multi-faceted knowledge translation intervention
- Where
- Canada
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Pain
MuscleCare™ Pain Relief Therapy vs. Voltaren® in the Relief of Trapezius Trigger Point Musculoskeletal Pain.
To determine the difference in efficacy of an all natural topical analgesic (MuscleCare) to a product containing the non-steroidal anti-inflammatory drug diclofenac (Voltaren) on trapezius trigger point pain.
- Trial name
- NCT03939884
- Testing
- MuscleCare Topical Product, Voltaren Topical, Nivea, Topical Cream
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Heart Failure, Chronic Obstructive Pulmonary Disease
TeleHomecaRe InterVention Evaluation Study
The goal of this study is to evaluate the overall impact of Telehomecare on COPD and HF patients and system level outcomes using a comparison group of patients that did not participate in the program (for up to 18 months).
- Trial name
- THRIVE (NCT03212001)
- Where
- Canada
- Volunteers
- 5,400 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Tooth Crown Fracture, Dental Caries
Clinical Performance of Ceramic CAD/CAM Crowns
The purpose of this study was to evaluate the clinical performance of laboratory and chairside fabricated monolithic anterior and posterior LDGC CAD/CAM crowns performed by predoctoral students at the University of Toronto and…
- Trial name
- NCT03921307
- Where
- Canada
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Increased Metabolic Requirement, Healthy
Protein Requirements In Active Populations
Protein requirements in active individuals have been suggested to be greater than the current recommended dietary allowance (RDA).
- Trial name
- NCT02478814
- Testing
- Amino Acid Intake
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Increased Metabolic Requirement, Healthy
Rate-limiting Amino Acids in Endurance-trained Athlete
Protein requirements in individuals who participate in endurance-based exercise training have been suggested to be greater than the current recommended dietary allowance (RDA).
- Trial name
- EA (NCT02628249)
- Testing
- Base protein, Sufficient protein, Branched chain amino acids
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Increased Metabolic Requirement, Healthy
Protein Requirements for Active Adolescent Females
Protein requirements in active individuals have been suggested to be greater than the current recommended dietary allowance (RDA).
- Trial name
- IAAO-AF (NCT02800239)
- Testing
- Amino Acid Intake
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Increased Metabolic Requirement, Healthy
Effect of Non-essential Amino Acids on Protein Requirements for Endurance Athletes
Protein requirements in individuals who participate in endurance-based exercise training have been suggested to be greater than the current recommended dietary allowance (RDA).
- Trial name
- EA3 (NCT02874638)
- Testing
- BASE egg protein, BCAA-enriched egg protein, small amount of essential amino acids
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
The Impact of Protein Intake on Protein Metabolism During Intensified Training
Protein requirements in individuals who participate in endurance-based exercise training have been suggested to be greater than the current recommended dietary allowance (RDA).
- Trial name
- NCT02801344
- Testing
- Normal, Moderate, High
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
Protein Requirements for Active Adolescent Males (IAAO-AM)
Protein requirements in active individuals have been suggested to be greater than the current recommended dietary allowance (RDA).
- Trial name
- NCT02859181
- Testing
- Amino Acid Intake
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Toronto