Clinical trials: sponsored by University of Toronto
Diabetes Mellitus, Type 2, Metabolic Syndrome X
Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases
There is an urgent need for stronger evidence to support recommendations for the role of sugars in diabetes and related cardiometabolic diseases.
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Syndrome X, Hypertension, Cardiovascular Diseases
- Trial name
- NCT02702375
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Increased Metabolic Requirement, Healthy
Protein Requirements in Endurance-trained Athlete
Protein requirements in individuals who participate in endurance-based exercise training have been suggested to be greater than the current recommended dietary allowance (RDA).
- Trial name
- EP (NCT02478801)
- Testing
- amino acids intake
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Diabetes
Acute Effects of Dietary Fiber on Postprandial Responses in Lean and Overweight Subjects
It has been suggested that obesity occurs because the colonic microbes in obese individuals, compared to those who are lean, produce more short chain fatty acids during the fermentation of dietary fiber; this means that obese…
- Trial name
- NCT02795559
- Testing
- Glucose, Inulin, Resistant starch
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Gestational Diabetes Mellitus
MAIN STUDY: Low Glycaemic Index (GI) Diet in the Management of GDM SUB-STUDY: The Breast Milk Sub-Study
MAIN STUDY: Low glycaemic index (GI) diets are recommended by the Canadian Diabetes Association for treating type 1 and 2 diabetes mellitus (DM), but the role of GI in the management of gestational diabetes(GDM)is not yet clear.
- Trial name
- GIinGDM (NCT01589757)
- Testing
- Standard Care, Low GI diet
- Where
- 4 sites in Canada
- Volunteers
- 99 people
- Sponsor
- University of Toronto
Muscle Fatigue, Muscle Strength
Short Term Omega-3 Supplementation on Performance
Nerves are the rate limiting factor that control muscle function. However, it is unknown if a nutritional supplement can change the nerve-muscle interaction, and therefore alter human performance.
- Trial name
- NCT02014233
- Testing
- Omega-3, Olive oil
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Dyslipidemia
Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk
The rise in high fructose corn syrup (HFCS) consumption over the past 40 years since its introduction as a popular sweetener in the United States has led to much concern regarding its contribution to the rise in obesity (1)…
- Conditions
- Obesity, Dyslipidemia, Prediabetes, Dysglycemia
- Trial name
- NCT02702479
- Testing
- High Fructose Corn Syrup, Sucrose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
TMD
What Are the Effects of Music on Temporomandibular Disorder Symptoms?
The purpose of the study will be to examine the effectiveness of an innovative use of music on TMD. Music and rhythmic vibrations can alter the basic processes related to sensation of pain in the brain.
- Trial name
- TMD (NCT02427113)
- Testing
- Sound Oasis Vibrating Chair, Self-Select Music
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes, Obesity
The Effect of Dairy and Non-dairy Alternatives on Satiety and Post-meal Glycemia in Healthy Young Adults
This study investigates the effects of commercially-available dairy (1% cow's milk and yogurt beverage) and non-dairy alternatives (almond and soy beverages) on satiety and post-meal blood glucose.
- Trial name
- NCT02491814
- Testing
- 1% M.F. Milk, Yogurt Beverage, Soy Beverage
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes, Obesity
The Effect of Dairy and Non-dairy Breakfasts on Satiety and Post-meal Glycemia in Healthy Older Adults
This study investigates the effects of dairy breakfasts (2% cow's milk, 2% Greek yogurt, cheese) and a non-dairy breakfast (soy beverage) on satiety and post-meal blood glucose.
- Trial name
- NCT02607007
- Testing
- 2% M.F. Milk, White Bread, Strawberry Jam
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Posttraumatic Stress Disorders
The Role of Affect Regulation and Self-presentation in the Expressive Writing Intervention
The purpose of the present study is twofold. First, we will attempt to examine the role that emotion regulation and self-presentation play as potential moderators in the expressive writing paradigm.
- Trial name
- NCT00831727
- Testing
- Expressive Writing, Control
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- University of Toronto
Social Stigma
Reducing Lesbian, Gay , Bisexual and Transgender (LGBT) Stigma in Swaziland and Lesotho
The specific objectives of this study are reduce stigma towards lesbian, gay, bisexual, and transgender persons in Swaziland and Lesotho, using performance ethnography at community roundtables.
- Trial name
- NCT02410434
- Testing
- LGBT Stigma Reduction Intervention
- Where
- 2 sites in Eswatini, Lesotho
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Acute HIV Infection
Effects of Intensive cART During Acute/Early HIV Infection
This trial will investigate the efficacy and safety of intensified antiretroviral treatment that includes raltegravir and maraviroc during the early stages of HIV infection.
- Trial name
- NCT01154673
- Testing
- raltegravir, maraviroc, emtricitabine 200mg /tenofovir 300mg
- Where
- 2 sites in Canada
- Volunteers
- 32 people
- Sponsor
- University of Toronto
Bacterial Vaginosis, HIV Infections
Effect of Bacterial Vaginosis on HIV Susceptibility and Female Genital Immunology
A non-randomized, interventional, longitudinal clinical study to quantify the impact of bacterial vaginosis treatment on HIV susceptibility and genital immunology in Kenyan women.
- Trial name
- NCT02527941
- Testing
- Metronidazole
- Where
- Kenya
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Childhood Obesity
Nutrition and Physical Activity Counselling
Background: Childhood obesity imposes a great burden on the healthcare system. Given the increased frequency of dental compared to medical visits during childhood, dentists may be in an ideal position to recognize patients at…
- Trial name
- NCT02637752
- Testing
- Lifestyle counseling or nutrition/physical counselling
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 2 Diabetes, Cardiovascular Disease
Low Glycemic Index Diets vs. High Cereal Fibre Diets in Type 2 Diabetes
Large observational studies have shown cereal fiber to protect from diabetes and heart disease. Despite the success of acarbose, an α-glucosidase hydrolase inhibitor, which lowers the glycemic index of foods containing starch…
- Trial name
- NCT00438698
- Testing
- Low Glycemic Index diet, High Cereal Fibre Diets
- Where
- Canada
- Volunteers
- 210 people
- Sponsor
- University of Toronto
Heart Disease, Diabetes
Fruits, Vegetables, and Whole Grains: A Community-based Intervention
The aim of this study is to see if the investigators can encourage people to eat more fruits, vegetables and whole grains and drink less pop by giving them advice about their diet, or by providing them with samples of different…
- Conditions
- Heart Disease, Diabetes, Hypertension
- Trial name
- NCT00516620
- Testing
- No further instruction, Food Delivery, Fruits (F), vegetables (V), and whole grain (WG) counseling
- Where
- Canada
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 2 Diabetes
Low Glycemic Index Diets (With Pulses) in Type 2 Diabetes
Healthy individuals with type 2 diabetes will receive intensive counseling on food selection to improve glucose control using either high cereal fiber dietary strategies or low glycemic index foods emphasizing dried legumes and…
- Trial name
- NCT01063361
- Testing
- Low glycemic index diet with pulses, High Cereal Fibre
- Where
- Canada
- Volunteers
- 131 people
- Sponsor
- University of Toronto
Type 2 Diabetes
Low Glycemic Index Diet (With Canola Oil) for Type 2 Diabetics
Healthy individuals with type 2 diabetes will receive intensive counseling on food selection to improve glucose control using either high cereal fiber dietary strategies or low glycemic index foods especially canola oil…
- Trial name
- NCT01348568
- Testing
- low glycemic index diet with canola oil bread, High fiber diet
- Where
- Canada
- Volunteers
- 141 people
- Sponsor
- University of Toronto
Obesity
The Acute Effect of Exercise on Appetite Appetite-regulating Hormones and Inflammation in Children
This study describes the effect of acute high intensity exercise at 70% VO2peak on inflammation, stress, appetite hormones and appetite in lean and obese children and adolescents.
- Trial name
- NCT02619461
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
Caffeine, Genetic Variation and Athletic Performance
Numerous studies have investigated the effect of caffeine on athletic performance, but the findings have not been consistent. This is due, in part, to the differences in response that has been observed both within and between…
- Trial name
- GMC-AP (NCT02109783)
- Testing
- Caffeine 2mg, Caffeine 4 mg, Caffeine 0
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toronto