Clinical trials: sponsored by University of Toronto
Glaucoma
The Effect of Body Posture on Intraocular Pressure in Progressive Glaucoma
Glaucoma is a condition where the optic nerve (the nerve responsible for sight) shows progressive damage with characteristic loss of visual field.
- Trial name
- NCT01351779
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Toronto
Diabetes Prevention, Obesity Prevention
Effects of Intact and Hydrolyzed Pea Protein on Food Intake, Glycemic Response and Subjective Appetite
The purpose of this protocol is to study the effects of intact and hydrolyzed yellow pea protein, compared to intact and hydrolyzed whey protein, on satiety, food intake, and glucose metabolism in healthy young men.
- Trial name
- NCT01298154
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes, Obesity
Comparing Liquid Versus Solid Forms of Sugars and Whey Protein
To compare the effect of eating solid vs. drinking liquid forms of gelatin, sucrose and its component mixtures and whey protein on subjective appetite and food intake in young men.
- Trial name
- NCT01348685
- Testing
- Compare the effect of solid vs. liquid forms of sugars on satiety and food intake, the effect of solid vs. liquid forms of gelatin on appetite and food intake, The effect of solid vs. liquid forms of whey protein on food intake
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Central Retinal Vein Occlusion
Retinal Blood Flow in Response to an Intravitreal Injection of Ranibizumab for Central Retinal Vein Occlusion (CRVO)
Ranibizumab (Lucentis, Genentech) is an off-label drug used for the clinical treatment of central retinal vein occlusion, which is one of the most common retinal vascular disorders.
- Trial name
- NCT01303276
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Oxidative Stress, Antioxidants
Effect of Acute Red Raspberry Consumption on Post-prandial Oxidative Stress
Eight healthy adult subjects will be given a meal of one, two or four cups red raspberries, or two slices white bread with or without 200 mg vitamin C, after an overnight fast and consumption of a low polyphenol diet for two…
- Trial name
- NCT01242033
- Testing
- red raspberries, bread controls
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Oxidative Stress
Effect of Red Raspberry Consumption on Fasting Oxidative Stress Biomarkers
The purpose of this study is determine whether daily consumption of frozen red raspberries can improve the antioxidant capacity of the blood and reduce the effects of oxidative stress, dose-dependently, in a healthy adult…
- Trial name
- NCT00876811
- Testing
- individually quick frozen red raspberries
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Glaucoma
Retinal Vascular Reactivity in Subjects With Newly Diagnosed Glaucoma Before and After Selective Laser Trabeculoplasty
The purpose of this study is to assess retinal blood flow and vascular reactivity in patients with newly diagnosed primary open angle glaucoma pre- and post-primary Selective Laser Trabeculoplasty(SLT).
- Trial name
- NCT01209975
- Testing
- Selective Laser Trabeculoplasty
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Toronto
Healthy Boys With no Emotional, Behavioral or Learning Problems Within a Normal Body Weight
Activity at 25% Above the Ventilation Threshold on Appetite and Food Intake in Boys
The investigators hypothesize exercise increases short term appetite and food intake, and interferes with satiety and satiations to a preload in normal weight, boys.
- Trial name
- HIE (NCT01196364)
- Testing
- Dietary Supplement: water with noncalorie sweetener, Activity: With noncalorie sweetener or glucose
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity Prevention
Activity at Ventilation Threshold on Appetite and Food Intake in Boys
The investigators hypothesize exercise increases short term appetite and food intake, and interferes with satiety and satiations to a preload in normal weight, overweight and obese boys.
- Trial name
- VeT (NCT01196351)
- Testing
- Dietary Supplement: water with noncalorie sweetener, Activity: With noncalorie sweetener or glucose
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Vitiligo Vulgaris
Ginkgo Biloba for the Treatment of Vitiligo Vulgaris in Adolescents
Vitiligo is a common hypopigmentation disorder with significant psychological impact if occurring before adulthood. One study investigating the use of Ginkgo biloba for the treatment of vitiligo in adults reports effectiveness…
- Trial name
- NCT00907062
- Testing
- Ginkgo biloba
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Attention Deficit Disorder
Working Memory Training in College Students With Attention-Deficit Hyperactivity Disorder/Learning Disabilities
The overall objective of the current study is to determine whether computerized Working Memory (WM) training will enhance WM capacity in college students with Attention Deficit Hyperactivity Disorder (ADHD)/Learning Disabilities…
- Trial name
- NCT01154686
- Testing
- Cogmed
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Toronto
Chronic Sinusitis
The Hemostatic and Hemodynamic Effects of Adrenaline During Endoscopic Sinus Surgery
Obtaining adequate hemostasis is crucial during endoscopic sinus surgery. Submucosal injection of local anaesthetic containing adrenaline has frequently been used to improve surgical milieu.
- Trial name
- NCT00852410
- Testing
- 1% lidocaine with 1:100,000 adrenaline, 1% lidocaine with 1:200,000 adrenaline
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 2 Diabetes Mellitus, Cardiovascular Disease
The Effect of a Traditional Dietary Intervention on Diabetes Mellitus and Cardiovascular Disease Risk Factors in a First Nation Community: A Pilot Study
The purpose of this study is to evaluate whether or not a traditional First Nations diet (high protein) and/or a dietary intervention based upon current Canadian dietary recommendations (high carbohydrate/high fiber) effects risk…
- Conditions
- Type 2 Diabetes Mellitus, Cardiovascular Disease, Obesity
- Trial name
- SLHDP (NCT00707460)
- Testing
- Dietary Intervention (Macronutrient composition)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Poor Ovarian Response
How Dose Coenzyme Q10 Supplementation During Infertility Treatment Effects Pregnancy Outcome
As women age the ovarian response and pregnancy rate are reduced while the rate of chromosomal abnormalities in the embryos is increased.
- Trial name
- CoQ10 (NCT00878124)
- Testing
- Coenzyme Q10 co treatment
- Where
- 2 sites in Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity Prevention
Television Viewing (TVV) & Puberty on Lunchtime Food Intake
The investigators hypothesize that television viewing will affect food intake in adolescent girls, and will depend on pubertal stage.
- Trial name
- NCT01025687
- Testing
- water with noncalorie sweetener, water with glucose, TV program showed while feeding
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity Prevention, Diabetes Prevention
Types of Starch and Their Effect on Blood Glucose, Appetite and Food Intake
The investigators hypothesize that different types of starch vary in their effects on appetite, blood sugar and food intake. In this study, subjects consumed five soups containing 50 g of whole grain, high amylose corn, regular…
- Trial name
- NCT00988689
- Testing
- Dietary Intervention
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes Prevention, Obesity Prevention
The Effect of Whey Protein on Short-Term Food Intake and Post-Meal Blood Glucose Response in Young Men
The objective of this study was to describe relationships among whey protein when consumed before a meal on food intake and pre- and post-meal satiety, blood glucose in healthy young adults.
- Trial name
- NCT00988377
- Testing
- dietary intervention, water control
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes Prevention, Obesity Prevention
The Effect of Whey Protein and Its Hydrolysate on Pre- and Post-Fixed Meal Glycemia and Insulin in Young Adults
The purpose of this study is to describe relationships among whey protein and its hydrolysate when consumed before a meal on pre- and post-fixed meal satiety, blood glucose and insulin in healthy young adults.
- Trial name
- NCT00988182
- Testing
- dietary intervention, water control
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity Prevention, Diabetes Prevention
Types of Starch and Their Effect on Blood Glucose, Appetite and Food Intake
The investigators hypothesize that different types of starch vary in their effects on appetite, blood sugar and food intake. In this study, subjects consumed five soups containing 50 g of whole grain, high amylose corn, regular…
- Trial name
- NCT00980941
- Testing
- soup with or without starch
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Dental Caries
Fluoride Varnish in the Prevention of Dental Caries in Aboriginal and Non-aboriginal Children
The purpose of this study is to determine whether semi-annual fluoride varnish applications combined with caregiver counseling are effective in preventing and reducing a severe form of dental decay, known as early childhood…
- Trial name
- NCT00435500
- Testing
- Fluoride varnish
- Where
- Canada
- Volunteers
- 1,320 people, healthy volunteers welcome
- Sponsor
- University of Toronto