Clinical trials: sponsored by University of Toronto
Parkinson Disease
DBS Virtual Learning Experience
The success of Deep Brain Stimulation (DBS) is more correlated to fulfillment of patients' expectations, than merely improvement of motor status1.
- Trial name
- NCT06436313
- Testing
- Educational Sessions
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Toronto
Parkinson Disease, Freezing of Gait Symptoms in Parkinson's Disease
Brain-Machine Interface for Freezing of Gait
Gait problems in Parkinson's disease (PD), especially freezing of gait (FOG), greatly affect quality of life. While deep brain stimulation (DBS) is a highly effective treatment for many motor symptoms of PD, it is less effective…
- Trial name
- NCT06642519
- Testing
- Brain Stimulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Toronto
Retinal Detachment
Animated Video Education for Retinal Surgery
Retinal detachment is a vision-threatening condition that requires urgent surgical repair. Understanding the condition, the surgery, and post-operative instructions is difficult for many patients, particularly in multilingual and…
- Trial name
- NCT07184255
- Testing
- Patient Education Video Intervention
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- University of Toronto
Metabolic Disturbance, Sedentary Behavior
Multiple Risk Factor Intervention Trial (Ms. FIT)
This study aims to produce new evidence, specific to women, on the efficacy and mechanisms of exercise and diet for cardiometabolic risk reduction in pre and postmenopausal women.
- Trial name
- MsFIT (NCT06345937)
- Testing
- Behavioural Experimental: guidelines-based physical activity, Behavioural Experimental: guidelines-based physical activity and healthy eating, Behavioural: Stretching exercise
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- University of Toronto
Spinal Cord Injury
SCI&U Peer Health Coaching Program for Individuals Newly Discharged From Inpatient Rehabilitation
The goal of this clinical trial is to learn if the online program and web-based platform for delivery of self-management services to people with spinal cord injury (SCI) called "SCI \& U" can support transitions from hospital to…
- Trial name
- SCIU2 (NCT06677905)
- Testing
- web-based spinal cord injury self-management program, Peer support
- Where
- 2 sites in United States, Canada
- Volunteers
- 76 people
- Sponsor
- University of Toronto
Malnutrition, Growth &Amp; Development
Effect of Maternal Supplementation From Preconception to Lactation on Child Growth and Development
The goal of this observational study is to learn about the long-term effects of maternal multiple micronutrient supplementation from preconception through to lactation on child neurodevelopment and growth in a resource-limited…
- Trial name
- NCT06641349
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- University of Toronto
Schizophrenia, Psychosis
Outcomes From Remediation and Behavioural Intervention Techniques
It is currently unknown what factors predict response to Cognitive Behavioural Therapy for Psychosis (CBTp) or Cognitive Remediation Therapy (CR) among individuals with schizophrenia-spectrum disorders, thus the current trial…
- Conditions
- Schizophrenia, Psychosis, Psychotic Disorders, Schizophrenia; Psychosis
- Trial name
- ORBIT (NCT05731414)
- Testing
- Cognitive Behavioural Therapy for Psychosis (CBTp), Cognitive Remediation Therapy (CR), Befriending
- Where
- 2 sites in Canada
- Volunteers
- 360 people
- Sponsor
- University of Toronto
Exercise
Does Biological Sex Influence Insulin Sensitivity and Muscle Metabolism Following High-intensity Interval Exercise?
High-intensity interval exercise (HIIE) is a type of exercise that involves alternating periods of intense exercise with periods of rest.
- Trial name
- NCT06074003
- Testing
- Seated Rest (Non-exercise control), High-intensity interval exercise
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 2 Diabetes
Community Gardens and Environmental Health in Mississauga
The goal of this clinical trial is to evaluate a revised version of Ecosource's 26-week community garden program. This project aims to assess how community gardening can reduce type 2 diabetes risk and improve health outcomes…
- Trial name
- NCT07112326
- Testing
- Community Gardening Program
- Where
- 4 sites in Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 2 Diabetes
Community-integrated Nutrition Education to Prevent Type 2 Diabetes in Peel
The goal of this clinical trial is to assess the effectiveness of an intervention that delivers nutrition education based on the Portfolio Diet on type-2 diabetes (T2D) risk factors among adults who are without chronic…
- Trial name
- NCT07058558
- Testing
- Nutrition Education and Community Gardening
- Where
- 2 sites in Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Psychotic Disorders, Schizophrenia
Virtual Cognitive Behavioural Therapy for Psychosis
Participants with schizophrenia-spectrum disorders who are experiencing active symptoms of psychosis will randomized to either receive 6 months of individual cognitive behavioural therapy for psychosis or to receive treatment as…
- Trial name
- NCT04752449
- Testing
- Virtual Cognitive Behavioural Therapy for Psychosis
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of Toronto
Psychotic Disorders, Executive Dysfunction
Examining Strategy Monitoring and Remediation Training
Executive Function Training is a cognitive training approach that specifically trains executive functioning for people with schizophrenia-spectrum disorders.
- Trial name
- E-SMART (NCT04756388)
- Testing
- Strategy Development, Computerized Cognitive Training
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Toronto
Psychotic Disorders, Schizophrenia and Related Disorders
EEG Outcomes From Cognitive Behavioural Therapy for Psychosis
Despite overwhelming evidence for neurocognitive and neurophysiological factors involved in the etiology of psychosis, these factors have never been examined as mechanisms of improvement from CBTp.
- Trial name
- EPIC (NCT05703698)
- Testing
- Cognitive Behavioural Therapy for Psychosis
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Toronto
Temporomandibular Disorders (TMD), Bruxism
Behavioral Interventions for Controlling Oral Behaviors
Ecological momentary assessment (EMA) interventions via mobile devices can be implemented to monitor an individual's negative health behaviors in real-time, increase awareness, and assist patients in overting those behaviors.
- Conditions
- Temporomandibular Disorders (TMD), Bruxism, Masseter
- Trial name
- NCT07022795
- Testing
- Educational video combined with daily surveys, Educational video only
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hiv
Tele-Coaching Community-Based Exercise (CBE) Study
The primary aim of this research is to evaluate the implementation of an online tele-coaching community-based exercise (CBE) intervention with adults living with HIV.
- Trial name
- NCT05006391
- Testing
- Tele-Coaching (Online) Community-Based Exercise
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- University of Toronto
Depression, Anxiety
Emotion Focused Therapy for Competitive Athletes
This project will be a pilot study to test the feasibility of using Emotion Focused Therapy (EFT) among competitive athletes experiencing mild-to-moderate depression or anxiety.
- Trial name
- NCT05896436
- Testing
- Emotion Focused Therapy
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of Toronto
Diabetes Mellitus
The REmission of Diabetes Using a PlAnt-based Weight Loss InteRvention (REPAIR) Trial
The goal of this clinical trial is to learn if a plant-based intensive lifestyle intervention can achieve remission of diabetes.
- Trial name
- REPAIR (NCT06906172)
- Testing
- Plant-based intensive lifestyle intervention, Standard of Care
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of Toronto
Mental Health Issue, Hiv
An Affirmative Coping Skills Intervention to Improve Mental and Sexual Health of Sexual and Gender Minority Youth
AFFIRM is an 8-session manualized group coping skills intervention focused on reducing sexual risk behaviours and psychosocial distress among SGMY.
- Conditions
- Mental Health Issue, Hiv, Stigma, Social, Coping Skills
- Trial name
- AFFIRM (NCT04318769)
- Testing
- AFFIRM
- Where
- 7 sites in Canada
- Volunteers
- 300 people
- Sponsor
- University of Toronto
Healthy Diet
Using FoodFlip© to Improve Food Choices Among Post-secondary Students
Canada passed mandatory front-of-package labelling (FOPL) regulations where pre-packaged food and beverage products that are high in sugar, saturated fat, and/or sodium are required to display a 'high-in' front-of-pack nutrition…
- Trial name
- NCT06033911
- Testing
- FoodFlip© App with no nutrition symbol, FoodFlip© App with 'high-in' nutrition symbol
- Where
- Canada
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Diabetes
Comparison of Pulse Chips and Commercial Snacks on Food Intake, Appetite and Blood Glucose in Healthy Young Adults
Consumers are often forced to eat fast, convenient foods and snacks ("eat on the go") in order to match the pace of their lifestyles. However, these snack options more often than not offer little health benefit to the consumer.
- Trial name
- NCT03297931
- Testing
- Corn Chips + Onion Dip, Yellow pea chip + hummus, Pinto bean chip + hummus
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Toronto