Clinical trials: sponsored by University of Toronto
Prenatal Community Program, Vulnerable Population
Parkdale Infant Nutrition Security Targeted Evaluation Project: Chart Review
In Toronto Ontario, the Parkdale Community Health Centre operates a community outreach program entitled Parkdale Parents' Primary Prevention Project (5P's).
- Conditions
- Prenatal Community Program, Vulnerable Population, Postnatal Community Program
- Trial name
- PINSTEP-1 (NCT03372408)
- Testing
- Chart review
- Where
- Canada
- Volunteers
- 338 people
- Sponsor
- University of Toronto
Breastfeeding, Breastfeeding, Exclusive
Providing Postnatal Breastfeeding Support Through the Canada Prenatal Nutrition Program
The Canada Prenatal Nutrition Program (CPNP) aims to improve birth outcomes among Canadian women in challenging life circumstances, including those who are adolescents, newcomers, low-income or single mothers.
- Conditions
- Breastfeeding, Breastfeeding, Exclusive, Infant Nutrition, Complementary Feeding
- Trial name
- PINSTEP-4 (NCT03589963)
- Testing
- Postnatal Lactation Support
- Where
- 2 sites in Canada
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, PreDiabetes
Network Meta-analysis of Intermittent Fasting and Cardiometabolic Risk
Intermittent fasting is a method of restricting calories over a defined period of time and includes regimens such as whole-day fasting, alternate-day fasting, and time-restricted feeding.
- Conditions
- Obesity, PreDiabetes, Diabetes, Hypertension
- Trial name
- NCT05309057
- Testing
- Intermittent Fasting
- Where
- 2 sites in Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Adults
Practical Approaches for Interrupting Prolonged Sitting to Improve Postprandial Glucose and Protein Metabolism
The present study will determine the impact of interrupting prolonged sitting with short, 2-minute walks or body-weight squats on: i) postprandial glycemia and insulinemia, and; ii) postprandial utilization of dietary amino…
- Trial name
- NCT03896828
- Testing
- Mixed-macronutrient meal
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Concussion, Brain
Post-acute Structured Exercise Following Sport Concussion
This study will investigate the effect of structured, standardized aerobic exercise (AE) compared to usual care on clinical recovery from sport-related concussion (SRC) within the post-acute phase of injury.
- Trial name
- NCT02969824
- Testing
- Supervised Aerobic Exercise
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University of Toronto
Mental Health
Mental Health Literacy and Mental Health Promotion With Urban Refugee Youth in Kampala, Uganda
From our previous studies, we know that urban refugee youth commonly report depressive symptoms. The primary aim of this study is to compare the effectiveness of youth-tailored interventions to improve mental health literacy and…
- Trial name
- NCT05187689
- Testing
- VR + MHL intervention, Group PM+
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Toronto
HIV/AIDS, HIV Infections
Tushirikiane HIV-self Testing Intervention With Urban Refugee Youth in Kampala, Uganda
HIV is the leading cause of death for adolescents and young people (AYP) in sub-Saharan Africa (SSA). Uganda hosts 1.3 million refugees/displaced persons, and more than 80,000 live in Kampala, most in slums, yet little is known…
- Conditions
- HIV/AIDS, HIV Infections, Knowledge, Attitudes, Practice
- Trial name
- Tushirikiane (NCT04504097)
- Testing
- m-Health, HIV self-testing
- Where
- Canada
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Knowledge, Attitudes, Practice, Post-exposure Prophylaxis
Comic Intervention for Sexual Violence Prevention and Post-rape Care
In humanitarian settings, sexual and gender-based violence disproportionately impacts women and children. However, there continues to be a lack of evidence regarding both sexual violence prevention and post-rape care…
- Trial name
- NCT04656522
- Testing
- Participatory Comic Intervention
- Where
- 2 sites in Canada, Uganda
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Knowledge, Attitudes, Practice, Covid19
mHealth Intervention for Increasing COVID-19 Prevention Practices With Urban Refugee and Displaced Youth in Uganda
Uganda hosts 1.4 million refugees, making it Sub-Saharan Africa's largest refugee host community and the third largest globally.
- Trial name
- NCT04631367
- Testing
- Kukaa Salama: mHealth intervention, Face Mask + Soap
- Where
- Canada
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hypertension, Cardiovascular Diseases
South Asian Low-sodium Trial
The overall goal of this pilot study is to examine the feasibility and acceptability of a culturally-tailored low-sodium dietary intervention is South Asian Canadians with stage one HTN.
- Trial name
- SALT (NCT05136911)
- Testing
- SALT-Intervention
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- University of Toronto
Depression, Anxiety
A Feasibility Study of an Emotion-Focused Mindfulness Group
Living with symptoms of mental illness is associated with psychosocial impairment as it can affect someone's ability to work, their relationships and level of functioning. This also has high economic costs on a societal level.
- Trial name
- NCT02987582
- Testing
- Emotion-focused mindfulness group
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Toronto Practice Based Research Network
Immunosuppression, Immune Tolerance
Liver Immune Tolerance Marker Utilization Study
The purpose of this study is to validate and test a tolerance gene expression profile for the identification of operationally tolerant liver transplant recipients, allowing for the successful withdrawal of immunosuppression…
- Trial name
- LITMUS (NCT02541916)
- Testing
- Controlled weaning of immunosuppression
- Where
- Canada
- Volunteers
- 69 people
- Sponsor
- University of Toronto
Food Marketing
Can a Coding Tool Accurately Evaluate How Kids Respond to Marketing on Food Packaging?
Child-appealing marketing for unhealthy foods and beverages is a global public health concern, and marketing on product packaging is one of children's top sources of exposure to this type of marketing.
- Trial name
- NCT04294121
- Testing
- Food marketing on product packaging
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Pain, Cardiac Ischemia
Development and Usability Testing of a Progressive WebApp for Women With Heart Disease
The overall goal of this program of research is to develop and systematically evaluate an integrated smartphone and web-based intervention (at heart [formerly called HEARTPA♀N]) to provide evidence-informed symptom triage and…
- Conditions
- Pain, Cardiac Ischemia, Women, Pain, Chronic
- Trial name
- at heart (NCT03800082)
- Testing
- at heart (changed from HEARTPA♀N during usability testing)
- Where
- Canada
- Volunteers
- 98 people
- Sponsor
- University of Toronto
Vaccine Adverse Reaction, Vaccination; Complications
Improving the School Vaccination Experience: What CARDs Are You Going to Play?
Vaccination hesitancy is identified as a threat to global health by the World Health Organization (WHO). For adolescents undergoing vaccination at school, prior studies demonstrate that concerns about pain and/or fear of needles…
- Conditions
- Vaccine Adverse Reaction, Vaccination; Complications, Fear
- Trial name
- NCT03966300
- Testing
- Multi-faceted knowledge translation intervention
- Where
- Canada
- Volunteers
- 1,919 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Heart Rate, Blood Pressure
Effect of High and Low Glycemic Index Foods on Post Meal Pulse and Blood Pressure
The aim of this study is to test high and low glycemic index foods in healthy adult volunteers and determine the effects on post meal pulse and blood pressure.
- Trial name
- NCT04910828
- Testing
- Common foods of varying glycemic indices
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Happiness, Anxiety
Prosocial Behavior Can Safeguard Mental Health and Foster Emotional Well-being During the COVID-19 Pandemic
The COVID-19 pandemic and the accompanying lockdown measures have made mental health a pressing public health concern. Acts that focus on benefiting others-known as prosocial behaviors-offer one promising intervention that is…
- Conditions
- Happiness, Anxiety, Depression, Morality
- Trial name
- NCT04517006
- Testing
- Self-focused acts, Prosocial acts
- Where
- Canada
- Volunteers
- 1,328 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes
Meta-analysis of Low GI/GL Diets and Cardiometabolic Risk in Diabetes
Low glycemic index and low glycemic load diets have been shown to improve glycemic control and cardiometabolic risk factors in randomized controlled trials in people with diabetes and are associated with reduced incidence of…
- Trial name
- NCT04045938
- Testing
- Low Glycemic Index or Glycemic Load
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Amino Acids, Dietary Protein
Influence of Sex and Training on de Novo Muscle Protein Synthesis
Acute exercise increases the incorporation of dietary amino acids into de novo myofibrillar proteins after a single meal in controlled laboratory studies in males.
- Conditions
- Amino Acids, Dietary Protein, Sex, Resistance Exercise
- Trial name
- TUT (NCT04887883)
- Testing
- Resistance exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Adult Males
Development of Oral Amino Acid Tracers to Study Protein Turnover in Humans
Previous studies have used a combination of oral L-[1-13C]leucine and intravenous labeled L-[5,5,5-2H3]leucine to assess the acute postprandial changes in whole-body protein turnover (12, 19).
- Trial name
- NCT04887727
- Testing
- Crystalline amino acids to assess myofibrillar protein synthesis rates, Crystalline amino acids to assess whole-body protein turnover, amino acid oxidation, and net protein balance
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Toronto