Clinical trials: sponsored by University of Toronto
Healthy, Overweight and Obesity
Strategies To OPpose Sugars With Non-nutritive Sweeteners Or Water (STOP Sugars NOW) Trial
Health authorities recommend a reduction in added sugars from sugar-sweetened beverages (SSBs) due to risk of obesity and diabetes. As a sugar-reduction strategy, finding the ideal SSB replacement is of the utmost importance.
- Conditions
- Healthy, Overweight and Obesity, Metabolic Syndrome, PreDiabetes
- Trial name
- NCT03543644
- Testing
- Sugar-sweetened beverage (SSB), Non-nutritive sweetened beverages (NSB), Water
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Communication Research, Breast Cancer
Randomized Trial of eOncoNote
Improving Cancer Care Together through eOncoNote is a pragmatic randomized trial involving a secure online eConsultation system (referred to as eOncoNote) that will allow primary care providers and cancer specialist providers to…
- Conditions
- Communication Research, Breast Cancer, Prostate Cancer, Colorectal Cancer
- Trial name
- NCT03333785
- Testing
- eOncoNote
- Where
- Canada
- Volunteers
- 181 people
- Sponsor
- University of Toronto
Women's Health
South Asian Women Together in a Health Initiative: A Pilot RCT
The overall goal of this pilot study is to assess the feasibility, acceptability and potential effects of a culturally tailored 12-week peer-based physical activity intervention compared with a control group, among young…
- Trial name
- SATHI (NCT03667976)
- Testing
- SATHI
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
Effect of Amino Acid on Muscle Damage
The primary objective is to determine the impact of essential amino acids on integrated muscle protein synthesis over 4 days after resistance exercise.
- Trial name
- NCT03319147
- Testing
- Active
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto
ARDS
Ultra-Low Tidal Volume Mechanical Ventilation in ARDS Through ECMO
Primary Research Question for the Full ULTIMATE Randomized Clinical Trial (RCT): What is the effect of ultra-protective ventilation facilitated by extracorporeal membrane oxygenation (ECMO) versus best current conventional…
- Trial name
- ULTIMATE (NCT04832789)
- Testing
- Venovenous ECMO
- Where
- 11 sites in United States, Canada
- Volunteers
- 72 people
- Sponsor
- University of Toronto
Stroke, Balance
Does a Group, Task-oriented Community-based Exercise Program Improve Everyday Function in People With Stroke?
After a stroke, people find it difficult to perform everyday activities independently, like getting dressed, preparing meals, and shopping, limiting their independence and requiring the assistance of a family member, friend or a…
- Conditions
- Stroke, Balance, Mobility Limitation, Activities of Daily Living
- Trial name
- NCT03122626
- Testing
- Together in Movement and Exercise (TIME) Program
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- University of Toronto
Parkinson Disease
Asymmetric Subthalamic Deep Brain Stimulation for Axial Motor Dysfunction in Parkinson's Disease
This single-center, randomized, quadruple-blinded, double-crossover comparative efficacy trial will study the effects of unilateral 50% voltage reduction in axial motor dysfunction for patients with Parkinson's disease that…
- Trial name
- NCT03462082
- Testing
- Asymmetric STN-DBS
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Toronto
Motor Development, Physical Activity
Evaluation of the Move 2 Learn (M2L) Program for Young Children
Move 2 Learn (M2L) is a 10-week movement and pre-literacy program for preschool aged children and their parents designed to improve both movement and reading skills as well as support their overall cognitive, physical, and…
- Trial name
- NCT03999619
- Testing
- Move 2 Learn
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Mobile Applications, Diet, Healthy
Systematic Review of Health App Gamification for Lifestyle Intervention Adherence
Health behaviour applications (also referred to as "apps") have the potential to provide several advantages for motivating behaviour change for health and well-being.
- Conditions
- Mobile Applications, Diet, Healthy, Behavior, Health
- Trial name
- NCT04633070
- Testing
- Gamification
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Sleep Deprivation
Feasibility, Acceptability and Effectiveness of the SOmNI Mobile Phone App for Sleep Promotion in Adolescents
This study evaluates the acceptability, feasibility, and efficacy of an intervention using wearable sensors and a mHealth application, SOmNI, to promote sleep for adolescents.
- Trial name
- SOmNI (NCT04089007)
- Testing
- SOmNI app, Control group
- Where
- Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy, Diabetes
Meta-analysis of Oats for Diabetes Prevention and Management
Oats are a commonly consumed source of viscous soluble fibre, which has an established role in cardiovascular disease risk management including in cholesterol and glycemic control.
- Conditions
- Healthy, Diabetes, Metabolic Syndrome, Overweight and Obesity
- Trial name
- NCT04631913
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Sarcopenia, Muscle Weakness
Functional Changes and Power Training in Older Women.
Extending quality of life and attenuating functional decline is paramount in older adults. This study investigates the effects of low-intensity power-training in older women and its effects on functional outcomes.
- Trial name
- F-POW (NCT02530723)
- Testing
- power training
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Consumer Behavior, Diet, Food, and Nutrition
FoodFLIP: Testing the Effectiveness of a Food Information App to Promote the Selection of Healthier Foods
There is a lot of confusion when it comes to understanding nutrition information on food packages, thus making it difficult for consumers to choose healthy products.
- Trial name
- NCT02814604
- Testing
- Nutrition Rating Systems
- Where
- Canada
- Volunteers
- 2,008 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Prostate Cancer
High-Intensity Training for Men With Prostate Cancer on Active Surveillance: A Feasibility Study
This is a randomized study aiming to assess the feasibility of a phase II randomized controlled trial of different high-intensity training interventions and usual care (UC) in men with prostate cancer (PCa) undergoing active…
- Trial name
- NCT04266262
- Testing
- High-intensity interval training (HIIT), High-Intensity resistance training (HIRT)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of Toronto
Type2 Diabetes, Heart Failure
Meta-analysis of Fish Oil Supplementation and Cardiovascular Outcomes in Diabetes
Fish oil contains a large amount of long-chain omega-3 polyunsaturated fatty acids, which are considered an important component of a healthy diet.
- Conditions
- Type2 Diabetes, Heart Failure, Myocardial Infarction, Stroke
- Trial name
- NCT04327713
- Testing
- fish oil supplement
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Type 2 Diabetes Mellitus, Obesity
Form of Dairy Products on Satiety, Food Intake and Post-meal Glycaemia in Young and Older Adults
The proposed study is planned to determine the potential role for regular fat dairy products in short-term metabolic control in younger and older adults and the metabolic flexibility in response to food components, which are…
- Trial name
- NCT02491801
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Paroxysmal Atrial Fibrillation
Atrial Electromechanical Function in Endurance Athletes With and Without Atrial Fibrillation
This study evaluates cardiac structure and function differences between healthy endurance trained athletes with atrial fibrillation and healthy age matched endurance trained athletes without atrial fibrillation.
- Trial name
- NCT03305744
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Blood Pressure
Comparison of Blood Pressure Measurements Between Transdermal Optical Imaging and Standard of Care
Participants (patients and volunteers) will be recruited to have their blood pressure measured by standard blood pressure assessment methods while having their face video recorded.
- Trial name
- NCT04539860
- Testing
- Transdermal Optical Imaging
- Where
- 3 sites in Canada, China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Voice Disorders, RRP
Comparison of BL and KTP Laser for Treatment of Benign Vocal Fold Lesions
Preliminary investigations suggest that a novel blue light (BL) laser with a wavelength of 445nm is comparable to the commonly utilized KTP laser (532nm) for treatment of laryngeal pathologies.
- Trial name
- NCT04513392
- Testing
- Laser treatment
- Volunteers
- 80 people
- Sponsor
- University of Toronto
Stigma, Social, HIV/AIDS
Transgender Education for Affirmative and Competent HIV and Healthcare
Educational workshops are an efficacious strategy to increase healthcare providers' ability to provide gender-affirming care for transgender (trans) people.
- Conditions
- Stigma, Social, HIV/AIDS, Health Care Acceptability
- Trial name
- TEACHH (NCT04096053)
- Testing
- TEACHH
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Toronto