Clinical trials: sponsored by Xijing Hospital
Ulcerative Colitis
Efficacy of Treatment With Berberine to Maintain Remission in Ulcerative Colitis
The research aim to find out whether berberine can reduce the annual recurrence rate of ulcerative colitis in remission. A total of 238 patients with ulcerative colitis in remission will be randomly divided into two groups.One…
- Trial name
- NCT02962245
- Testing
- berberine, regular treatment
- Sponsor
- Xijing Hospital of Digestive Diseases
Crohn's Disease, Oral Ulcer
The Efficacy of Topical Mesalazine Sustained-Release Tablets in Crohn's Disease Patients With Oral Ulcer
This study aims at evaluating efficacy and safety of topical using Mesalazine Sustained-Release Tablets in in the treatment of oral ulcers in patients with Crohn's disease.
- Trial name
- NCT02769494
- Testing
- Mesalazine Sustained-Release Tablets, Riboflavin Sodium Phosphate Injection
- Where
- China
- Sponsor
- Xijing Hospital of Digestive Diseases
Refractory Reflux Esophagitis
Trimebutine Maleate Combined With Rabeprazole in Patients With Grade A or B Reflux Esophagitis Whose Symptoms Refractory to Rabeprazole
The research aims to investigate whether trimebutine maleate combined with rabeprazole can improve the clinical efficacy in patients With refractory Los Angeles grade A or B reflux esophagitis .
- Trial name
- rRE (NCT02986685)
- Testing
- Trimebutine Maleate, rabeprazole
- Where
- China
- Sponsor
- Xijing Hospital of Digestive Diseases
Bile Reflux, Gastric Cancer
Associations Among Serum and Gastric Juice Bile Acid Profile, Bile Acid-microbiota Cross-talk in Stomach and the Development of Gastric Cancer
To explore the associations among bile acid profile, bile acid-microbiota cross-talk and the development of gastric cancer, so as to better prevent the occurrence and development of gastric cancer
- Conditions
- Bile Reflux, Gastric Cancer, Precancerous Lesion
- Trial name
- NCT04660058
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Dyspepsia, Chronic Gastritis
Helicobacter Pylori Eradication With Berberine Plus Amoxicillin Triple Therapy Versus Bismuth-containing Quadruple Therapy
This study aims at evaluating efficacy and safety of berberine hydrochloride, amoxicillin and rabeprazole triple therapy versus bismuth-containing quadruple therapy(amoxicillin, clarithromycin, rabeprazole and bismuth) in the…
- Conditions
- Dyspepsia, Chronic Gastritis, Gastric Cancer, Helicobacter Pylori Infection
- Trial name
- NCT04697186
- Testing
- Berberine, Amoxicillin, Rabeprazole
- Where
- China
- Volunteers
- 524 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Gastritis, Dyspepsia
Helicobacter Rescue Therapy With High-dose Esomeprazole and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy
This study aims at evaluating efficacy and safety of high-dose esomeprazole and amoxicillin dual therapy(esomeprazole and amoxicillin) versus bismuth-containing quadruple Therapy(bismuth，esomeprazole，tetracycline and…
- Conditions
- Gastritis, Dyspepsia, Helicobacter Pylori Infection, Gastric Cancer
- Trial name
- NCT04678492
- Testing
- Esomeprazole, Amoxicillin, Bismuth
- Where
- China
- Volunteers
- 658 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Gastric Cancer, Helicobacter Pylori Infection
A Real World Study of Bismuth Colloidal Pectin Granules Quadruple Therapy for H. Pylori Eradication
To observe the eradication rate of H. pylori infection, symptom improvement and the incidence of adverse effects in patients using a bismuth colloidal pectin granules quadruple therapy.
- Conditions
- Gastric Cancer, Helicobacter Pylori Infection, Bismuth
- Trial name
- NCT04660123
- Testing
- Bismuth Colloidal Pectin Granules Quadruple Therapy for H. Pylori Eradication
- Where
- China
- Volunteers
- 959 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Helicobacter Pylori Infection, Chronic Gastritis
Study on The Efficacy and Safety of Berberine-containing Triple Therapy in Helicobacter Pylori First-Line Eradication
The purpose of this study is to assess the efficacy and safety of berberine, amoxicillin and vonoprazan containing triple therapy in Helicobacter Pylori first-line eradication.
- Trial name
- NCT05014334
- Testing
- Berberine, Vonoprazan, Amoxicillin
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Sepsis, Prognosis
Study on the Establishment of a System for Early Warning and Prognostic Evaluation of Patients With Sepsis
Sepsis is a clinical syndrome with high morbidity and high fatality rate in emergency department. Patients with acute liver or kidney injury are more likely to develop Multiple Organ Dysfunction Syndrome(MODS) secondary to the…
- Conditions
- Sepsis, Prognosis, Liver Injury, Kidney Injury
- Trial name
- NCT05229328
- Testing
- Peripheral blood test
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
ESCC
DCF Combined With Camrelizumab in the Treatment of Esophageal Cancer
To evaluate the safety and feasibility of DCF combined with camrelizumab in the treatment of locally advanced ESCC
- Trial name
- NCT05050760
- Testing
- Camrelizumab, DCF
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Xijing Hospital
Esophageal Squamous Cell Carcinoma
The Efficacy of N-acetylcysteine on Alleviating Symptom Caused by Lugol Chromoendoscopy
Lugol chromoendoscopy is essential in detecting and characterizing squamous cell carcinoma of esophagus. Esophageal irritating symptom has been reported as an common adverse event, which could be alleviated by sodium thiosulfate…
- Trial name
- NCT04764643
- Testing
- N-acetylcysteine solution, sodium thiosulfate solution
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Nausea and Vomiting
The Safety and Effectiveness of Palonosetron Hydrochloride Capsule Was Used to CINV
To observe and evaluate the safety and effectiveness of Palonosetron hydrochloride capsule in preventing acute nausea and vomiting caused by moderate emetic chemotherapy; The characteristics of the applicable population, clinical…
- Trial name
- TSEPHCC (NCT05690802)
- Testing
- Palonosetron hydrochloride capsules
- Where
- China
- Volunteers
- 1,060 people
- Sponsor
- Xijing Hospital
Postoperative Pain
Comparison of Postoperative Pain Application of Alfentanil or Remifentanil in TIVA
Total intravenous anesthesia (TIVA) is maintained by intermittent or continuous combined intravenous injection of a variety of short-acting intravenous anesthetics, which can provide safe and rapid induction, maintenance and…
- Trial name
- TIVA (NCT05344911)
- Testing
- Propofol combined with alfentanil, Propofol combined with remifentanil
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Data Collecting and Analyzing of Different Treatment of Structural Heart Diseases
Surgery and Transcatheter Intervention for Structural Heart Diseases
This project aimed to optimize the therapeutic strategy for structural heart disease by choosing optimal treatment, such as,surgical treatment,interventional and surgery combined with interventional hybrid treatment.
- Trial name
- NCT02917980
- Where
- China
- Volunteers
- 883 people
- Sponsor
- Xijing Hospital
Drug Refractory Epilepsy
cTBS Targeting Cerebellum for Drug-refractory Epilepsy
This study aims to observe the effect and safety of cerebellar continuous θ burst stimulation (cTBS) for drug-refractory epilepsy(DRE), in order to provide a new treatment for DRE and improve the quality of life of those…
- Trial name
- NCT05042726
- Testing
- cTBS First, Pseudo-stimulation First
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Xijing Hospital
Stroke Patients
Prevention and Treatment of Reperfusion Injury After Mechanical Thrombectomy in Acute Ischemic Stroke
Ischemic stroke accounts for 80% of all strokes and there is a lack of effective treatment options.Mechanical thrombectomy can significantly improve the vascular recanalization rate and reduce the disability rate of stroke, but…
- Trial name
- NCT05282290
- Testing
- Antihypertensive drugs (no restriction on the type of drugs)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital
Disorder of Consciousness
Gamma Entrainment Improve the Recovery of Awareness
The purpose of this study is to elucidate the occurrence of Gamma entrainment and optimize the acousto-optic stimulation parameters to induce it in patients with disorders of consciousness (DOC), to explore the prognostic value…
- Trial name
- NCT05640544
- Testing
- Sound and light stimulation in Gamma band
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Gut Microbiota
Establishment of Individualized Immunotherapy Strategy and Platform Based on Changes of Intestinal Microbiota
To explore and analyze the relationship between intestinal flora changes and the efficacy of individualized immunotherapy in patients with upper gastrointestinal cancer, and to find new biomarkers to predict the efficacy of…
- Trial name
- NCT05065515
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Chronic Total Occlusion of Coronary Artery
Antegrade and Retrograde Dissection and Re-entry Approach for CTO
BACKGROUND：Chronic total occlusion (CTO) angioplasty is one of the most challenging procedures remaining for the interventional operator.
- Trial name
- LOTUS (NCT03769038)
- Testing
- chronic total occlusion
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Helicobacter Pylori
Vonoprazan Hp Dual or Triple Eradication Regimes
To evaluate the efficacy and safety of dual or triple regimes for Helicobacter Pylori eradication using Vonoprazan as the antiacid agent.
- Trial name
- NCT05345210
- Testing
- Vonoprazan Fumarate+Amoxycillin+Clarithromycin 14days (VAC14), Vonoprazan Fumarate+Amoxycillin 14days (VA14), Vonoprazan Fumarate+Amoxycillin 7days (VA7)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xijing Hospital of Digestive Diseases