Clinical trials: sponsored by Xijing Hospital
Peripheral Nerve Injuries
Preliminary Evaluation of the Clinical Safety and Effectiveness of the Bionic Nerve Scaffold
The objective of the study is to preliminarily evaluate the clinical safety and effectiveness of the bionic nerve scaffold with longitudinally oriented microchannels.
- Trial name
- NCT03780855
- Testing
- nerve scaffold
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xijing Hospital
Type 2 Diabetes Mellitus
Comparison of Exenatide vs. Biphasic Insulin Aspart 30 on Glucose Variability in Type 2 Diabetes
This is a multi-centre, open-label, randomized, parallel trial to compare the effect of Exenatide versus Biphasic insulin Aspart 30 on glucose variability and inflammatory markers in type 2 diabetes mellitus (T2DM) patients…
- Trial name
- NCT02449603
- Testing
- Exenatide, Biphasic insulin Aspart 30
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital
Prediabetes
Effects of Berberine Hydrochloride and Bifidobacterium in Prediabetes Prevention and Treatment
The aim of this study is to assess the beneficial effects of Bifidobacterium and Berberine Hydrochloride on lowering glucose and delaying progress to diabetes in patients with prediabetes and to detect the potential mechanism.
- Trial name
- NCT02082756
- Testing
- Bifidobacterium viable pharmaceutics, Berberine Hydrochloride
- Where
- 4 sites in China
- Sponsor
- Xijing Hospital
Type 2 Diabetes Mellitus
Effects of Berberine Hydrochloride and Bifidobacterium in Diabetes Mellitus Prevention and Treatment
The aim of this study is to assess the beneficial effects of Bifidobacterium Hydrochloride and Berberine on lowering glucose in patients with type 2 diabetes mellitus and to detect the potential mechanism.
- Trial name
- NCT02084004
- Testing
- Bifidobacterium viable pharmaceutics, Berberine Hydrochloride
- Where
- 4 sites in China
- Sponsor
- Xijing Hospital
Surgical Flaps, Skin Pigmentation
Evaluation of the Postoperative Effect of Expanded Pedicled Deltopectoral Flap to Repair the Facial-Cervical Scars
This study evaluates the effect of Expanded Pedicled Deltopectoral Flap on facial-cervical scars repair, including flap sensation, L*a*b* value,flap's elasticity,melanin content, hemoglobin content, and evaluation of scar and…
- Conditions
- Surgical Flaps, Skin Pigmentation, Sensory Defect
- Trial name
- NCT03735641
- Testing
- Expanded Pedicled Deltopectoral Flap
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Tic Disorder, Childhood
A Study of Cranial Electrotherapy Stimulation as an Add-on Treatment for Tic Disorders (SCATT)
Tic disorders is recognized as a neuropsychiatric disease. The treatments of tic disorders include drug therapy, psychotherapy and physical therapy.
- Trial name
- SCATT (NCT03705988)
- Testing
- Cranial Electrotherapy Stimulation(CES)
- Volunteers
- 100 people
- Sponsor
- Xijing Hospital
Hypertrophic Cardiomyopathy, Depression
Efficacy of Psychotherapy for Improving Quality of Life in Patients With Hypertrophic Cardiomyopathy and Depression
A Study to evaluate the efficacy of psychotherapy for easing the cardiac symptoms and improving and quality of life in patients with hypertrophic cardiomyopathy accompanied with depression
- Conditions
- Hypertrophic Cardiomyopathy, Depression, Anxiety, Psychotherapy
- Trial name
- NCT03706001
- Testing
- Psychotherapy
- Volunteers
- 100 people
- Sponsor
- Xijing Hospital
Acute-On-Chronic Liver Failure
Mesenchymal Stem Cell Transplantation for Acute-on-chronic Liver Failure
Mesenchymal stem cells (MSC) has been reported to improved outcomes of acute-on-chronic liver failure(ACLF). More randomization controlled studies are needed to confirm the effect of MSC treatment for ACLF.
- Trial name
- NCT03668171
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Primary Biliary Cirrhosis
Mesenchymal Stem Cell Transplantation for Refractory Primary Biliary Cholangitis
Ursodeoxycholic acid is the mainstay treatment medicine for primary biliary cholangitis(PBC). About 1/3 of the patients do not respond to UDCA, which is defined as refractory PBC.
- Trial name
- NCT03668145
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Liver Cirrhosis
Trial of Mesenchymal Stem Cell Transplantation in Decompensated Liver Cirrhosis
There has been great interest in recent years to take advantage of stem cells to treat liver cirrhosis. Mesenchymal stem cells (MSC) has been shown to be safe and effective for liver diseases in some studies.
- Trial name
- NCT03209986
- Testing
- mesenchymal stem cell transplantation via peripheral vein, mesenchymal stem cell
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Spinal Cord Injuries, Photobiology
Clinical Study of Treatment of Acute Spinal Cord Injury by Near Infrared Light Irradiation
The purpose of this study was to observe the therapeutic effect of near-infrared light irradiation on the treatment of acute spinal cord injury in humans, and whether it can promote the recovery of neurological function.
- Conditions
- Spinal Cord Injuries, Photobiology, Neurological Rehabilitation, Near Infrared Light Irradiation
- Trial name
- NCT03643419
- Testing
- Laminectomy, Spinal nerve laser therapeutic apparatus（Composed of 808-band fully automatic control laser device and implantable 360° scattering medical fiber）
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Depressive Disorder, Major
Probing Prefrontal Cortex Hemodynamic Alterations for Major Depression Disorder
Major depression disorder (MDD) has high estimated lifetime prevalence rates of 16.6%. Currently, the diagnosis for the MDD mainly depends on patients' reports of symptoms, observed behaviors and disease course.
- Trial name
- MDD (NCT03595020)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Polyps, Colorectal Neoplasm
Colorectal Polyps Screening With Low-dose CT Colonoscopy
This preliminary clinical trial aims to evaluate the performance of the low-dose CT colonoscopy (CTC) with computer aided detection (CAD) on polyps detection compared with optical colonoscopy (OC), and explore the possible…
- Trial name
- NCT03064828
- Testing
- CT colonoscopy(normal dose), CT colonoscopy (low dose)
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Vancomycin
Vancomycin in the Target Site Treatment of Intracranial Infection
Vancomycin, a novel intravenously administered antibiotic, currently plays a key role in the management of complicated multi-organism infections.
- Trial name
- NCT03585426
- Testing
- Vancomycin
- Volunteers
- 2 people
- Sponsor
- Xijing Hospital
Burn
Research on the Key Technology of Burn Wound Treatment
Burns are common injuries in the daily life and wars. With the development of medical techniques, the mortality has been significantly reduced.
- Trial name
- NCT03279549
- Testing
- Routine dressing change, Limited debridement & Acellular dermal matrix dressing, Limited debridement & Epidermal cell spraying
- Volunteers
- 200 people
- Sponsor
- Xijing Hospital
Postoperative, Acute Pain
TEAS-induced Analgesia: Dual vs Single Acupoints
The purpose of this study is to evaluate the effects of transcutaneous electric acupoint stimulation(TEAS) at single acupoint or dual acupoints on opioid consumption and postoperative pain in patients undergoing radical mastectomy
- Conditions
- Postoperative, Acute Pain, Chronic Pain
- Trial name
- TADS (NCT02543580)
- Testing
- transcutaneous electric acupoint stimulation, electrode attached but no stimulation
- Where
- China
- Volunteers
- 153 people
- Sponsor
- Xijing Hospital
Quality of Life
Effects of Camouflage on the Life Quality of Patients With Vitiligo
Vitiligo is a common depigmented skin disease characterized by destruction of functional melanocyte.The recent therapies to vitiligo are including oral or external glucocorticoids, antioxidants, calcineurin inhibitors or…
- Trial name
- NCT03540966
- Testing
- CapulinTM, Chinese version of the vitiligo life quality index, VLQI-C
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Gene Product Sequence Variation
Candidate Gene Screening for Attention Deficit/Hyperactive Disorder (ADHD)
Source: Sample bank of Xijing Hospital and Children's Hospital Affiliated to Soochow University; Sample form: Whole blood; Estimated number of samples: 100 patients with ADHD and age, sex matched healthy controls; Case exclusion…
- Trial name
- NCT03018574
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Hyperthyroidism
A Trial for the Evaluation of the Treatment and Outcome of Hyperthyroidism With Iodized Salt and Non Iodized Salt
To clarify the influence of iodine intake in salt on the incidence and treatment of hyperthyroidism patients, so as to provide theoretical basis for accurate formulation of iodine intake in salt, and provide strategies for…
- Trial name
- NCT03444246
- Testing
- Iodine free diet group, Normal iodine diet group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Heart Valve Diseases, Heart; Complications, Valve, Prosthesis
Prevention of Renal Failure by Nitric Oxide in Prolonged Cardiopulmonary Bypass.
Prolonged periods of cardiopulmonary bypass (CPB) cause high levels of plasma free haemoglobin(Hb) and are associated with increased morbidity.
- Conditions
- Heart Valve Diseases, Heart; Complications, Valve, Prosthesis, Cardiac Valve Replacement Complication
- Trial name
- NCT01802619
- Testing
- inhaled nitric oxide, inhaled Nitrogen
- Where
- China
- Volunteers
- 217 people
- Sponsor
- Xijing Hospital