Clinical trials: sponsored by Xuanwu Hospital, Beijing
Adult Spinal Deformity, Sagittal Deformity
A Novel Classification of Sagittal Spinal Alignment to Aid Surgical Planning for Adult Spinal Deformity
Surgical outcomes, including radiographic outcomes, patient-reported outcomes, postoperative complications, and revision surgery rates, were compared in patients with adult spinal deformity who underwent correction surgery with…
- Conditions
- Adult Spinal Deformity, Sagittal Deformity, Sagittal Alignment, Sagittal Imbalance
- Trial name
- CSSAASD (NCT06470152)
- Testing
- Correction strategy in reference to our PI-dependent clustering of sagittal alignment, Correction strategy in reference to the SAAS score
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
VaD-MCI
Clinical Multicenter Randomized Controlled Study of Simultaneous Cognitive Training With Transcranial Magnetic Stimulation in the Treatment of VaD-MCI Patients
A multicenter randomized controlled clinical study was conducted in the Xuanwu hospital of Capital Medical University to preliminarily explore the efficacy and safety of simultaneous cognitive training with transcranial magnetic…
- Trial name
- NCT06470113
- Testing
- simultaneous cognitive training with transcranial magnetic stimulation
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Xuanwu Hospital, Beijing
Age Problem, Disability
Beijing Disability Risk and Ageing Monitoring Study
This is a community-based prospective cohort study in Beijing, China. The study has been initialized in 2023 and enrolled older residents.
- Conditions
- Age Problem, Disability, Death
- Trial name
- BEAM (NCT06394817)
- Testing
- No intervention
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Treatment
Pipeline Embolization Device for the Treatment of Intracranial Aneurysms on the Long Term Safety and Efficacy
Since its launch in China in 2014, Pipeline Embolization Device (PED) has been widely used in the treatment of intracranial aneurysms.
- Trial name
- NCT06456697
- Where
- China
- Volunteers
- 482 people
- Sponsor
- Xuanwu Hospital, Beijing
Parkinson Disease
AV133 Longitudinal Imaging Study in Patients With Early and Prdromal Parkinson's Disease
A total of 38 patients with early-stage Parkinson's disease and 38 patients with prodromal Parkinson's disease are planned to be enrolled in this study and examined for longitudinal changes in [18F]AV-133 through follow-up…
- Trial name
- NCT06456684
- Testing
- Fluoro[18F]promethazine
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Xuanwu Hospital, Beijing
Multiple Sclerosis, NMO Spectrum Disorder
National, Multicentric Registry Study on Neuroimmunological Diseases in China
The aim of this study is to establish a real-world clinical neuroimmune disease research cohort, to follow up and observe the prognosis of patients with different subtypes and subgroups, and to provide support for the treatment…
- Conditions
- Multiple Sclerosis, NMO Spectrum Disorder, Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease, Myasthenia Gravis
- Trial name
- NIDBase (NCT06443333)
- Testing
- Data collection and follow-up observation, Data collection
- Where
- China
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Disorder of Consciousness
Study of Brain Function Evaluation and Intervention System for Acute and Prolonged Disorders of Consciousness
The research focuses on establishing a system for validating the effectiveness of key technologies for targeted combined non-invasive interventions in awakening consciousness.
- Trial name
- NCT05682248
- Testing
- Transcranial magnetic stimulation
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke
Registry of Acute Ischemic Stroke With Large- or Medium-vessel Occlusion
This study is designed to observe the treatment options in real-world clinical practice as well as the safety and efficacy of different treatment strategies.
- Trial name
- LOMEVO (NCT05779215)
- Testing
- Visit at D90
- Where
- China
- Volunteers
- 50,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Hydrocephalus, Idiopathic Normal Pressure Hydrocephalus
Clinical Outcome in Patients With INPH
The aim of this study is to determine the clinical spectrum and natural progression of idiopathic normal pressure hydrocephalus （iNPH ) and related disorders in a prospective single center study, identify digital, imaging and…
- Conditions
- Hydrocephalus, Idiopathic Normal Pressure Hydrocephalus, CSF, Glympathic System
- Trial name
- NCT06428734
- Testing
- hydrocephalus group, normal group
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Cognitive Impairment, Mild, Dementia
Effects of Training Dose on Computerized Cognitive Training in Patients With Cognitive Impairment
The goal of this observational study is to explore the optimal dose of computerized cognitive training in patients with cognitive impairment.
- Trial name
- NCT05922319
- Testing
- Computerized cognitive training with different training doses
- Where
- China
- Volunteers
- 21,845 people
- Sponsor
- Xuanwu Hospital, Beijing
Patent Foramen Ovale
Long-term Procedural and Device Related Complications of PFO Closure
We aimed to explore: (1）long-term complications of PFO closure; (2) antiplate or anticoagulation use after PFO closure.
- Trial name
- NCT06413147
- Testing
- PFO closure
- Volunteers
- 100 people
- Sponsor
- Xuanwu Hospital, Beijing
Myocardial Infarction
Warning Model of Myocardial Remodeling After Acute Myocardial Infarction Using Multimodal Feature Structure Technology
Acute myocardial infarction (AMI) is one of the most important diseases threatening human life. The existing MI prognosis prediction scales mostly predict the incidence of death, recurrent MI and heart failure through 6-8…
- Trial name
- NCT06062316
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Syringomyelia
Subarachnoid-Subarachnoid (S-S) Bypass Versus Adhesion Lysis in Spinal Arachnoiditis and Syringomyelia
To determine whether Subarachnoid-Subarachnoid (S-S) Bypass results in better patient outcomes with fewer complications and improved quality of life compared to intradural adhesion lysis in individuals with Spinal Arachnoiditis…
- Trial name
- NCT06375759
- Testing
- Subarachnoid-Subarachnoid (S-S) Bypass, Intradural Adhesion Lysis
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Subarachnoid Hemorrhage
Transcranial Alternating Current Stimulation Prevents Delirium in Patients With Subarachnoid Hemorrhage
The goal of this clinical trial is to learn about using the latest transcranial alternating current stimulation (tACS) to reduce the incidence of delirium in patients with subarachnoid hemorrhage.
- Trial name
- TACS (NCT06375408)
- Testing
- Real transcranial alternating electrical stimulation
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Xuanwu Hospital, Beijing
Patent Foramen Ovale
Anticoagulants for PFO Patients
Patients who underwent both bubble transcranial Doppler (bubble-TCD) and transoesophageal echocardiography (TEE) at our institution were consecutively enrolled in this real-world case-control study from August 2016 through August…
- Trial name
- NCT06375070
- Testing
- PFO closure, anticoagulant
- Volunteers
- 277 people
- Sponsor
- Xuanwu Hospital, Beijing
Cerebral Angiography, Heparinization
Safety and Efficacy of Low-dose hEparinization in Cerebral Angiography sTudy
Purpose: Systemic heparinization is a widely used technique on digital subtraction angiography (DSA). Heparin, however, is associated with a variety of complications, including hemorrhage, thrombocytopenia, and hematomas.
- Trial name
- SELECT (NCT06365398)
- Testing
- Heparin, Heparin Sodium Injection, No heparinization
- Where
- 2 sites in China
- Volunteers
- 180 people
- Sponsor
- Xuanwu Hospital, Beijing
Tourette's Syndrome
Exploring DBS Efficacy in Treatment-refractory Tourette's Syndrome
The primary purpose of this study is to investigate the effect of deep brain stimulation (DBS) in patients with Treatment-refractory Tourette's syndrome (TR-TS) implantation targeting the Antero-medial globus pallidus interna…
- Trial name
- NCT06361004
- Testing
- Deep Brain Stimulation (DBS)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xuanwu Hospital, Beijing
Obsessive-Compulsive Disorder (OCD)
DBS for Treatment-resistant Obsessive-compulsive Disorder
The primary purpose of this study is to investigate the effect of deep brain stimulation (DBS) implantation targeting the anteromedial region of subthalamic nucleus (amSTN), or nucleus accumbens (NAc), or bed nucleus of the stria…
- Trial name
- NCT06360991
- Testing
- Deep brain stimulation (DBS)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xuanwu Hospital, Beijing
Carotid Stenosis, Ischemic Stroke
Comprehensive Assessment of Atherosclerotic Ischemic Stroke Risk and Development of a Prediction Model
This observational study was designed for the assessment of plaque vulnerability in patients with carotid atherosclerotic stenosis and the development of predictive models for the occurrence and recurrence of atherosclerotic…
- Trial name
- CAIS-pre (NCT06315153)
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- Xuanwu Hospital, Beijing
Syringomyelia
The Therapeutic Effect of Betaine in Syringomyelia
Purpose: This clinical trial aims to evaluate the indications, therapeutic effects and side effects of betaine in refractory syringomyelia. Primary outcome measure: The primary endpoint is the change of ASIA at week 12.
- Trial name
- NCT06308367
- Testing
- Betaine
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xuanwu Hospital, Beijing