Clinical trials: sponsored by Xuanwu Hospital, Beijing
Syringomyelia/Hydromyelia
Clinical Outcome in Patients With Syringomyelia（COPSM）
The aim of this study is to determine the clinical spectrum and natural progression of Syringomyelia (SM) and related disorders in a prospective single center study, identify digital, imaging and molecular biomarkers that can…
- Trial name
- NCT04856839
- Testing
- high throughput sequencing and electromyography
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Parkinson's Disease
rTMS for the Treatment of Freezing of Gait in Parkinson's Disease
This study is a double blind comparative study examining the effectiveness of the rTMS treatment on Freezing of Gait (FOG) in patients with Parkinson's disease (PD).
- Trial name
- NCT03219892
- Testing
- High-frequency rTMS
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xuanwu Hospital, Beijing
Nutrition Disorders, Neurologic Disorder
The Effects of Enteral Whey Protein Supplement on Serum Albumin Level in Acute Critically Ill Neurological Patients
The incidence of malnutrition in patients with severe neurological diseases is approximately 37%, among which hypoproteinemia is a common manifestation.
- Trial name
- NCT04361357
- Testing
- whey protein
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Xuanwu Hospital, Beijing
Parkinson Disease
LRRK2 Activity and Markers of Parkinson's Disease in G2385R Carriers
The goals of this study are 1. To compare the functional effects of the LRRK2 G2385R variant among carriers with and without Parkinson's disease (PD) and non-carriers with and without PD 2.
- Trial name
- NCT04349865
- Where
- China
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Central Nervous System (CNS) Infection, Encephalitis
Establishment of Prevention and Control System of Central Nervous System Infection
Central nervous system (CNS) infection is a common nervous system acute and severe disease, mainly manifested as encephalitis, meningitis and meningoencephalitis, but also manifested as brain abscess and brain granuloma et al.
- Conditions
- Central Nervous System (CNS) Infection, Encephalitis, Meningitis
- Trial name
- NCT04722328
- Testing
- CSF metagenomic next generation sequencing (mNGS)
- Where
- China
- Volunteers
- 715 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Acute
Rehabilitative BCI in Acute Ischemic Stroke
In order to explore the role and expound the mechanism of rehabilitative brain computer interface (BCI)-based training (referred to as the Walk Again Neurorehabilitation protocol) in neurofunctional reconstruction in acute phase…
- Trial name
- NCT04704427
- Testing
- Non-invasive BCI training, Traditional Physiotherapy protocol
- Volunteers
- 40 people
- Sponsor
- Xuanwu Hospital, Beijing
Combined Central and Peripheral Demyelination Disease
The Clinical Features of Combined Central and Peripheral Demyelination
The investigators conduct this study to clarify the clinical features and to evaluate the prevalence of anti-nodal/paranodal antibodies of patients with combined central and peripheral demyelination (CCPD) .
- Trial name
- CCPD (NCT04664647)
- Volunteers
- 30 people
- Sponsor
- Xuanwu Hospital, Beijing
Transcranial Alternating Current Stimulation
Atlas of Intracranial Recordings on Cortical Responses After Functional tACS
By analyzing the SEEG recordings, we explore the range of cortical functional responses to strings of 77.5Hz stimulations delivered by tACS,
- Trial name
- AIRCRAFT (NCT04560959)
- Testing
- tACS
- Volunteers
- 30 people
- Sponsor
- Xuanwu Hospital, Beijing
Sleep Apnea Syndromes, Atherosclerosis
The Influence of Mandibular Advancement Device Treating OSAHS on Primary Prevention of Ischemic Stroke
1. The purpose of this study is to detect the differences of carotid atherosclerosis severity between patients with or without OSAHS(Obstructive Sleep Apnea and Hypopnea Syndrome) in a cross-sectional study in a large sample. 2.
- Conditions
- Sleep Apnea Syndromes, Atherosclerosis, Carotid Plaque
- Trial name
- NCT03665818
- Testing
- oral appliance treatment
- Volunteers
- 100 people
- Sponsor
- Xuanwu Hospital, Beijing
Pancreatitis,Acute Necrotizing, Pancreas Necrosis
Perform Necrotic Cavity Lavage or Not After Debridement of Infected Pancreatic Necrosis
The infected pancreatic necrosis (IPN) should be treated by debridement and drainage. In recent years, the results of clinical research show that minimally invasive debridement such as video-assisted (laparoscope, nephroscope…
- Trial name
- NCLAD (NCT04275466)
- Testing
- necrotic cavity lavage
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Xuanwu Hospital, Beijing
Glioma of Brain, Recurrence
Efficacy of Kangliuwan for Recurrent Grade IV Glioma
A Prospective Exploratory Clinical Study to explore the efficacy of Hospital Traditional Chinese Medicine Preparation Kangliuwan for Recurrent Grade IV Glioma.
- Trial name
- NCT03949192
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Xuanwu Hospital, Beijing
Prostate Cancer
PD-L1-expressing Regulatory T Cells in Localized Prostate Cancer Patients Undergoing Iodine-125 Permanent Brachytherapy
Immunotherapy is currently revolutionizing the field in oncology. However, prostate cancer is poorly responsive to immune checkpoint inhibition.
- Trial name
- NCT04369508
- Testing
- permanent brachytherapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Renal Cell Carcinoma
RFR Change of Precise Segmental Versus Complete Renal Arterial Clamping During LPN for Clinical T1 RCC
Renal functional reserve may be better in patients with clinical T1 renal cell carcinoma(RCC) undergoing laparoscopic partial nephrectomy with precise segmental renal artery clamping than those with complete renal arterial…
- Trial name
- NCT03259477
- Testing
- precise segmental renal arterial clamping, laparoscopic partial nephrectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xuanwu Hospital, Beijing
Spinal Vascular Disorder Nos, Neurogenic Bladder Dysfunction Nos
Measurement of Bladder Function Change In Patients With SVMs Before and After Surgical Intervention
The investigators goal is to create a better understanding of patient with SVMs reported outcomes for bladder management strategies before and after surgery.
- Trial name
- NCT03280186
- Testing
- surgery
- Volunteers
- 100 people
- Sponsor
- Xuanwu Hospital, Beijing
Spinal Vascular Disorder Nos, Overactive Bladder
Efficacy Comparison Between Different Management Strategies for Consistent OAB in Patients With SVMs After Surgery
The investigators' goal is to compare the efficacy of three different management strategies (sacral neuromodulation, botulinum toxin, M receptor antagonist) in treating consistent OAB in patients with SVMs after surgery.
- Trial name
- NCT03280316
- Testing
- surgery, sacral neuromodulation, botulinum toxin A injection
- Volunteers
- 100 people
- Sponsor
- Xuanwu Hospital, Beijing
Atherosclerosis of Artery, In-stent Arterial Restenosis
Clinical Study of Excimer Laser and Drug Coated Balloon Versus Excimer Laser and Plain Balloon Versus Plain Balloon and Drug Coated Balloon to Treat Femoropopliteal In-stent Restenosis
This is a randomized study comparing Excimer laser and drug coated balloon Versus Excimer laser and plain balloon versus plain balloon and drug coated balloon to Treat femoropopliteal in-stent restenosis
- Trial name
- Excellent (NCT04365062)
- Testing
- Excimer laser and drug coated balloon, Excimer laser and plain balloon, plain balloon and drug coated balloon
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Xuanwu Hospital, Beijing
Iliac Artery Occlusion
Clinical Study of Stent Versus Direct Atherectomy to Treat Iliac Artery Occlusive Diseases
This is a randomized study comparing stent and plaque excision systems in treatment of Iliac artery occlusive disease.
- Trial name
- NCT04361071
- Testing
- stent, plaque excision system
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xuanwu Hospital, Beijing
Transcranial Magnetic Stimulation, Parkinson Disease
TMS Treatment in Parkinson's Disease With Pain.
Transcranial magnetic stimulation (TMS) is a procedure that has been shown to improve pain in chronic sufferers. It is a well-tolerated procedure that can be performed on an outpatient basis.
- Conditions
- Transcranial Magnetic Stimulation, Parkinson Disease, Pain
- Trial name
- TMSPDP (NCT04048265)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Xuanwu Hospital, Beijing
Cerebral Edema
Molecular Mechanisms of Malignant Cerebral Edema After LHI
The study is to explore the molecular mechanisms underlying the occurrence of malignant cerebral edema (cerebral hernia) after large hemispheric infarction.
- Trial name
- LHI (NCT03703284)
- Testing
- Treatments to reduce intracranial pressure
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Non-small Cell Lung Cancer
Cancer Genome Atlas of China:Lung Cancer
Based on 2500 lung cancer tumor tissue samples from about 40 clinical centers in China, the molecular typing of lung cancer in China will be figured out by high throughput sequencing, which will provide the basis for the…
- Trial name
- NCT04266483
- Where
- 34 sites in China
- Volunteers
- 2,500 people
- Sponsor
- Xuanwu Hospital, Beijing