Clinical trials: sponsored by Xuanwu Hospital, Beijing
Non-small Cell Lung Cancer
Cancer Genome Atlas of China:Lung Cancer
Based on 2500 lung cancer tumor tissue samples from about 40 clinical centers in China, the molecular typing of lung cancer in China will be figured out by high throughput sequencing, which will provide the basis for the…
- Trial name
- NCT04266483
- Where
- 34 sites in China
- Volunteers
- 2,500 people
- Sponsor
- Xuanwu Hospital, Beijing
Spinal Cord Astrocytoma
Genomic Landscape of Intramedullary Astrocytoma
intramedullary astrocytoma is a rare and devastating spinal cord glioma. while the management of intracranial astrocytoma includes gross total resection, radiotherapy and chemotherapy, spinal cord astrocytoma is very difficult to…
- Trial name
- GIMA (NCT04211974)
- Testing
- whole-exome sequencing
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xuanwu Hospital, Beijing
Atherosclerosis, In-stent Arterial Restenosis
Clinical Study of Stent Versus Direct Atherectomy Versus Angioplasty to Treat Lower Limb In-stent Restenosis
This is a randomized study comparing Stent Versus Direct Atherectomy Versus Angioplasty to Treat Lower Limb In-stent Restenosis (superficial femoral or popliteal artery).
- Trial name
- NCT02832024
- Testing
- plaque excision system, stent, Balloon
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xuanwu Hospital, Beijing
Atherosclerosis, Ischemia
Clinical Study of Stent Versus Direct Atherectomy to Treat Arteriosclerosis Occlusive Disease of Lower Extremity
This is a randomized study comparing stent and plaque excision systems in treatment of Arteriosclerosis occlusive disease of lower extremity (superficial femoral or popliteal artery)
- Trial name
- NCT02840786
- Testing
- plaque excision system, balloon and Stent
- Where
- China
- Volunteers
- 221 people
- Sponsor
- Xuanwu Hospital, Beijing
Lung Cancer Stage II, PD-1 Antibody
A Study of SHR-1210 in Combination With Carboplatin+Paclitaxel-albumin in Subjects With Resectable NSCLC
This study is a randomized, controlled, open-label, prospective, single-center phase II clinical study. Target population is patients with stage II and IIIA resectable non-small cell lung cancer who had not received systemic…
- Conditions
- Lung Cancer Stage II, PD-1 Antibody, Non-small Cell Lung Cancer
- Trial name
- NCT04108013
- Testing
- SHR-1210, Carboplatin and Paclitaxel-albumin
- Volunteers
- 38 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke, Atrial Fibrillation
Registration Study of Acute Ischemic Stroke/Transient Ischemic Attack (TIA) With Atrial Fibrillation
Patient Registration Study of Acute Ischemic Stroke/transient ischemic attack(TIA) With Atrial Fibrillation (AISWAF) is a single-center prospective, consecutively, observational study, was conducted in patients with acute…
- Trial name
- AISWAF (NCT04080830)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Post-stroke Depression
Transcranial Alternating Current Stimulation Treating Post-stroke Depression
Post-stroke depression (PSD) is one of the most common complications after stroke, with a high prevalence. PSD can affect prognosis and rehabilitation of stroke, increase risks of mortality and suicide, and escalate the economic…
- Trial name
- NCT03903068
- Testing
- NEXALIN ADI AC stimulator, Pseudo-stimulator
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Xuanwu Hospital, Beijing
Chronic Paraplegia
Training With Brain-machine Interfaces, Visuo-tactile Feedback and Assisted Locomotion for Patients With Chronic Complete Paraplegia
The purpose of this research is to compare the effectiveness of a training protocol integrating Brain-machine Interfaces, Visuo-tactile feedback and Assisted Locomotion (referred to as the Walk Again Neurorehabilitation protocol…
- Trial name
- NCT03992690
- Testing
- Brain-machine Interfaces, Visuo-tactile Feedback and Assisted Locomotion, or the WANR protocol, Training with traditional physiotherapy protocol
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xuanwu Hospital, Beijing
Generalized Convulsive Status Epilepticus
Phenobarbital Versus Valproate for Generalized Convulsive Status Epilepticus
Although generalized convulsive status epilepticus (GCSE) is a life-threatening emergency, evidence-based data to guide initial drug treatment choices are lacking in the Chinese population.
- Trial name
- NCT03025906
- Testing
- Phenobarbital, Valproate
- Where
- 6 sites in China
- Volunteers
- 120 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Lymphoblastic Leukemia
CD19 hsCAR-T for Refractory/Relapsed CD19+ B-ALL Patients
This Phase II study is to evaluate the efficacy and safety of a CD19-targeting humanized selective CAR-T (CD19 hsCAR-T) in refractory/relapsed CD19+ B-ALL leukemia patients who have no available curative treatment options, have a…
- Trial name
- NCT03902197
- Testing
- CD19 hsCAR-T
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Xuanwu Hospital, Beijing
Lung Cancer, Breast Cancer
Clinical Study on Anti-tumor Effect Induced by Activated Primary Natural Killer（NK）Cells
This study will analyze and evaluate the following items: 1. The safety of natural killer（NK） cells for treatment of subjects with solid tumors.
- Conditions
- Lung Cancer, Breast Cancer, Colon Cancer, Pancreatic Cancer
- Trial name
- NCT03634501
- Testing
- Activated NK
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Popliteal Stenosis, Popliteal Artery Occlusion
DCB Compared Stenting in Popliteal Lesions
This is a randomized prospective study aiming to compare drug-coated balloons and stent deployment in Popliteal atherosclerotic occlusive lesions.
- Conditions
- Popliteal Stenosis, Popliteal Artery Occlusion, Diabetes
- Trial name
- NCT03739580
- Testing
- DCB angioplasty (Orchid, Acotec Scientific Co. Ltd.), Stent (Maris,Medtronic.USA or Sinus/Supera, Germany)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xuanwu Hospital, Beijing
Subclavian Occlusion
Bare-metal Stent vs Covered Stent in Chinese Patients With Subclavian Occlusive Lesions
Bare-metal stent vs Covered stent with subclavian occlusive lesions to verify the efficacy and safety.Study Design are prospective, multiple center, randomized, open, positive controlled, non-inferiority trail.Case total numbers…
- Trial name
- BASELINE (NCT03737162)
- Testing
- Stent implantation of subclavian artery
- Where
- 6 sites in China
- Volunteers
- 408 people
- Sponsor
- Xuanwu Hospital, Beijing
Carotid Stenosis
Endarterectomy vs Stenting in Chinese Asymptomatic Carotid Stenosis Patients
Endarterectomy vs Stenting Asymptomatic Carotid stenosis patients to verify the efficacy and safety.
- Trial name
- ESCALATE (NCT03737175)
- Testing
- Carotid Artery Stenting, Carotid Endarterectomy
- Where
- 6 sites in China
- Volunteers
- 600 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke
TCD Monitoring Technology Guides the Precise Control of Blood Pressure After EVT
Investigators hypothesized that the precise regulation of blood pressure based on the changes of cerebral blood flow parameters under TCD monitoring can better improve the state of cerebral blood flow, reduce the risk of early…
- Trial name
- NCT03529149
- Testing
- Urapidil Hydrochloride Injection
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xuanwu Hospital, Beijing
Intracranial Aneurysm
Evaluation of Postoperative Cognitive Function, Anxiety, Depression and Quality of Life in Patients With Unruptured Intracranial Aneurysms
This prospective single-center cohort study aims to identify the incidence of cognitive dysfunction after unruptured aneurysm operation and explore the influencing factors.
- Trial name
- NCT03494608
- Volunteers
- 350 people
- Sponsor
- Xuanwu Hospital, Beijing
Cerebrovascular Disease
Individualized Antithrombotic Therapy for Patients With Ischemic Cerebrovascular Disease
To investigate the therapeutic effect of individualized treatment of antiplatelet in secondary prevention of ischemic stroke.
- Trial name
- NCT03471169
- Testing
- Desirable TEG, Undesirable TEG
- Where
- China
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Neuro-Degenerative Disease
Large Sample PD Patients and Healthy Controls
Resting-state functional magnetic resonance imaging (RS-fMRI) has frequently been used to investigate local spontaneous brain activity in Parkinson's disease (PD) in a whole-brain, voxel-wise manner.
- Trial name
- NCT03439163
- Testing
- MRI scan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Hypothermia, Aneurysmal Subarachnoid Hemorrhage
Trial of Long-term Therapeutic Hypothermia for Poor-grade Aneurysmal Subarachnoid Hemorrhage
This study is a prospective, multi-centre, randomized,controlled trial to compare the efficacy of long-term mild hypothermia with normothermic intensive management in patients with poor-grade aneurysmal subarachnoid hemorrhage.
- Trial name
- NCT03442608
- Testing
- Zoll 2000 and/or CureWrap 3500 cooling system
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke
Evaluation Of HUK in Acute Stroke Patients: MRS and CTP
Background: Acute ischemic stroke (AIS) is a leading cause of morbidity and mortality worldwide. Human urinary kallidinogenase (HUK), a glycoprotein extracted from male urine currently used in China for enhancing cerebral…
- Trial name
- NCT03431909
- Testing
- Human urinary kallidinogenase (HUK), aspirin® , clopidogrel® , atorvastatin®
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing