Clinical trials: sponsored by Zagazig University
Mastectomy, Postoperative Pain
s Serratus Anterior Block for Perioperative Analgesia
Modified radical mastectomy is one of the commonly performed breast surgery. Postoperative pain following mastectomy should be minimised, as in a number of women it may chronically persist for months in the form of postmastectomy…
- Trial name
- NCT06410378
- Testing
- Erector Spinae Plane Block, Serratus Anterior Plane Block, controll group
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Zagazig University
Acne Vulgaris
Anti-microbial Role of Non-antibiotic Agents Against Cutibacterium Acnes in Patients With Acne Vulgaris
To evaluate and compare the anti-biofilm activity of Salicylic acid, Isotretinoin, and N-acetylcysteine against C. acne . To assess the possible role of Salicylic acid, Isotretinoin, and N-acetylcysteine in improving the…
- Trial name
- NCT06179056
- Testing
- assess the possible role of Salicylic acid, Isotretinoin, and N-acetylcysteine in improving the susceptibility of C. acne for Azithromycin and Doxycycline.
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Colorectal Cancer
Incidence and Risk Factors of Low Anterior Resection Syndrome
Sphincter sparing surgery is oftentimes associated with bowel dysfunction complaints, namely the low anterior resection syndrome (LARS). The LARS questionnaire is widely used to assess this syndrome.
- Trial name
- NCT06359730
- Testing
- LARS score questionnaire
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Zagazig University
Embryo Implantation, ART
The Impact of Endometrial Compaction on Assisted Reproductive Technology Outcome
Absence of endometrial compaction on the day of ET has adverse effects on success of ART outcome.
- Trial name
- NCT04721522
- Testing
- blood sampling & ultrasound
- Where
- Egypt
- Volunteers
- 356 people
- Sponsor
- Zagazig University
Non-alcoholic Fatty Liver Disease
Semaglutide in Nonalcoholic Fatty Liver Disease
The goal of this clinical trial is to test the therapeutic effect of Semaglutide in NAFLD and its sequelae in obesity and/or type 2 diabetes mellitus.
- Trial name
- NCT05813249
- Testing
- Rybelsus Oral Product, Ozempic Injectable Product, Tocopherol and/or Actos
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Zagazig University
Adrenal Tumor
Side-specific Factors for Conversion in Adrenalectomy for Pheochromocytoma.
Context: Adrenalectomy for pheochromocytoma (PHEO) poses difficulties due to the elevated chance of conversion. The objective of this study was to conduct a comparative analysis of the occurrence and determinants of conversion in…
- Trial name
- NCT06330558
- Testing
- laparoscopic right adrenalectomy
- Volunteers
- 271 people
- Sponsor
- Zagazig University
Laparoscopic Surgery
Laparoscopic Splenectomy in Isolated High Grades Splenic Injuries
Background: Trauma laparoscopic splenectomy has no defined reasons. Compared trauma patient characteristics and results with laparoscopic and open splenectomies.
- Trial name
- NCT04329845
- Testing
- open splenectomy, laparoscopic splenectomy for splenic injury in trauma
- Volunteers
- 2 people
- Sponsor
- Zagazig University
Ilioinguinal Nerve Section, Pain Prevention
Prophylactic Ilioinguinal Neurectomy During Open Tension-Free Inguinal Hernia Repair
postoperative chronic inguinal pain is a common postoperative complication after open inguinal hernia repair. Chronic inguinal pain is a common complication following open inguinal hernia repair.
- Conditions
- Ilioinguinal Nerve Section, Pain Prevention, Hernioplasty
- Trial name
- NCT06327763
- Testing
- ilioinguinal nerve section
- Where
- Egypt
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Colorectal Cancer
Prognostic Factors Influencing the Recurrence Rate and Survival of Patients With Colorectal Cancer: a Single Institution Experience
over the past decade colon cancer has emerged as the second most deadly and the third most common type of cancer in the world with increasing incidence in Egypt due to life style and diet change.
- Trial name
- NCT06325410
- Testing
- resection of colorectal cancer
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Zagazig University
Perianal Fistula
Diagnostic Value of Recto-perineal Ultrasound in Perianal Fistula
Perianal fistula is a common anal problem. It needs only surgery. MRI is the best preoperative diagnostic tool, but it is demanding as it is expensive, time consuming and needs an experienced radiologist.
- Trial name
- NCT06314945
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Zagazig University
Suicide and Depression
Accelerated Theta Burst Stimulation for Treatment of Suicidality in Depressed Patients
The objective of this study is to investigate efficacy of accelerated theta burst stimulation (TBS) in suicidal reduction in patients with unipolar and bipolar depression
- Trial name
- NCT06289842
- Testing
- Transcranial Magnetic Stimulation MagPro R30 with the MCF-B70 figure-of-eight coil (MagVenture, Denmark)
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Zagazig University
Procedural Sedation
Dexmedetomidine and Midazolam Nebulization as Sedation During Cesarean Delivery in Pre-eclampsia
Null hypothesis: There is no difference between the effects of nebulization of dexmedetomidine and midazolam as procedural sedation during cesarean delivery under spinal Anesthesia in pre-eclamptic parturients Alternative…
- Trial name
- NCT04873596
- Testing
- Nebulized dexmedetomidine, Nebulized midazolam
- Where
- Egypt
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Analgesia
Ultrasound Guided Retrolaminar Versus Erector Spinae Plane Block for Postoperative Analgesia
Thoracic epidural anesthesia (TEA) and paravertebral block (PVB) have been utilized to give perioperative regional anesthesia in the trunk.
- Trial name
- NCT04531215
- Testing
- ultrasound guided Retrolaminar Block, ultrasound guided Erector Spinae Plane
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Anesthesia Intubation Complication
Dexmedetomidine or Lidocaine for Lessening the Hemodynamic Responses to Laryngoscopy and Intubation
Laryngoscopy, tracheal intubation, surgical stimulation, and extubation unleash remarkable sympathetic activity and are associated with transient but significant hemodynamic changes.
- Trial name
- NCT05941767
- Testing
- Dexmedetomidine nebulization, Lidocaine nebulization, Dexmedetomidine IV
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Sickle Cell Disease, Vitamin D Deficiency
High Dose Vitamin D Supplementation in Children With Sickle Cell Disease
Suboptimal vitamin D status is well reported in sickle cell disease (SCD) patients and associated with a negative impact on health-related quality of life (HRQL).
- Conditions
- Sickle Cell Disease, Vitamin D Deficiency, Health Related Quality of Life, Hand Grip Strength
- Trial name
- NCT06274203
- Testing
- Vitamin D3
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Breast Neoplasms
New Formula to Predict the Need for Reconstructive Coverage Following Mastectomy
Mastectomy is a cornerstone operative procedure in breast cancer treatment leaving a raw area behind with possibility of failure of primary closure sometimes with unavailability of facilities of reconstruction.
- Trial name
- NCT04677075
- Testing
- mastectomy
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Zagazig University
Obesity, Morbid, Endoscopy
Endoscopic Gastric Reduction of Gastric Mucosa in Obesity
In the stomach, the ghrelin-containing cells are more abundant in the fundus than in the pylorus originally termed X/A-like cells.
- Trial name
- ETO (NCT06231251)
- Testing
- upper gastrointestinal endoscopy
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Cardiac Surgery
Transversus Thoracis Plane Block Versus Parasternal Intercostal Nerve Plane Block for Cardiac Surgery
Traditionally postoperative pain management after cardiac surgery has been based on opiate analgesics. However, opiates have some undesirable dose-related side-effects such as nausea, constipation, vomiting, dizziness, mental…
- Trial name
- NCT06155097
- Testing
- transversus thoracis muscle plane block (TTP), parasternal intercostal nerve block (PSI block)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Zagazig University
Knee Osteoarthritis
Adherence to Treatment in Egyptian Patients With Knee Osteoarthritis
the aim is to measure the level of adherence of knee osteoartheritis patients to a Carefully curated program that follows the American College of Rheumatology/Arthritis (ACR) recommendation guidelines and investigate the factor…
- Trial name
- OA (NCT06064253)
- Testing
- health education
- Where
- Egypt
- Volunteers
- 154 people
- Sponsor
- Zagazig University
Melasma
Oral Isotretinoin in Melasma a Randomized Controlled Trial
Melasma is a common refractory acquired hyperpigmentation of the skin having a serious impact on patients' quality of life. Melasma is challenging to treat. Treatment is often a multimodality approach.
- Trial name
- NCT06201624
- Testing
- Isotretinoin, Triple combination formula
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Zagazig University