Clinical trials: sponsored by Zealand University Hospital
Delirium
External Validation of Delirium Prediction Models for Intensive Care Patients
Delirium is frequently observed among critically ill patients and is associated with detrimental outcomes. Currently, no evidence-based prevention or treatment exists for delirium, and especially, the inability to identify…
- Trial name
- NCT05084482
- Testing
- Prediction models
- Where
- Denmark
- Volunteers
- 660 people
- Sponsor
- Zealand University Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Reducing Sedentary Behavior in Patients with Severe COPD: a Feasibility Study on Nurse-Led Motivational Intervention
This feasibility study aims to assess the practicality and acceptability of a nurse-led motivational interview intervention designed to reduce sedentary behavior in patients with severe Chronic Obstructive Pulmonary Disease…
- Trial name
- NCT06882863
- Testing
- Motivational interviewing
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Zealand University Hospital
Lung Cancer, Lymphoma
Improving Genomic Profiling and Reducing Time to Cancer Treatment Via Targeted Use of Endoscopic Ultrasound
Aim: To investigate whether the novel 3rd generation FNB needle provides a better diagnostic accuracy than a standard FNA needle in EUS-B guided diagnosis of common deep seated thoracic malignancies (lung cancer and lymphoma).
- Conditions
- Lung Cancer, Lymphoma, Sarcoidosis
- Trial name
- IMPROVED (NCT06848738)
- Testing
- FNB, FNA
- Where
- 3 sites in Denmark
- Volunteers
- 362 people
- Sponsor
- Zealand University Hospital
Expectations, Surgery
Patients' Expectations Before Spinal Surgery
With this study the investigators want to perform a prospective observational cohort study at Zealand University Hospital, Koege, Denmark. The purpose of this study is twofold: 1.
- Conditions
- Expectations, Surgery, Pain, Quality of Life
- Trial name
- NCT06080997
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Zealand University Hospital
Schizophrenia, Schizophrenia Spectrum and Other Psychotic Disorders
Sex, Psychopharmacology, and Diabetes
The term sexual (SD) dysfunction covers conditions that prevent people from having a satisfactory sex life. SD is a frequent and sometimes debilitating complication of mental illness and a known adverse reaction to…
- Conditions
- Schizophrenia, Schizophrenia Spectrum and Other Psychotic Disorders, Diabetes Mellitus, PreDiabetes
- Trial name
- SECRET (NCT05951660)
- Testing
- Educational intervention
- Where
- Denmark
- Volunteers
- 256 people
- Sponsor
- Zealand University Hospital
Shoulder Fractures
Rehabilitation Following Displaced Proximal Humerus Fractures
Proximal humerus fractures (PHFs) are the third most common non-vertebral fractures in the elderly. Most elderly experience loss of function following a PHF regardless of treatment.
- Trial name
- NCT05302089
- Testing
- Pain management and shoulder bandage, One-time physiotherapy instruction, Usual rehabilitation care
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Zealand University Hospital
COVID-19, SARS-CoV-2
Biomarkers for Post-COVID Conditions
The COVID-19 infection affects humans differently. While some recover quickly and fully, others develop serious illnesses and late complications.
- Conditions
- COVID-19, SARS-CoV-2, Biomarkers, Post-acute COVID-19 Syndrome
- Trial name
- NCT05196516
- Where
- Denmark
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Dementia, Dementia With Lewy Bodies
Monitoring Anti-Dementia Drugs by Serum Levels
The main objective of the MONANTI study is twofold: Firstly, to determine the serum concentration (SC) the anti-dementia drugs donepezil and memantine in a broadly defined clinical population of patients suffering from dementia…
- Conditions
- Dementia, Dementia With Lewy Bodies, Dementia in Parkinsons Disease, Dementia Alzheimers
- Trial name
- MONANTI (NCT04117178)
- Testing
- Donepezil, Memantine, Measurement of serum level of anti-dementia drug
- Where
- Denmark
- Volunteers
- 132 people
- Sponsor
- Zealand University Hospital
Distal Forearm Fracture, Distal Radius Fracture
Is Casting of Displaced Pediatric Distal Forearm Fractures Non-inferior to Reduction in General Anesthesia?
Treatment of displaced distal forearm fractures (DFF) in children have traditionally been closed reduction and pin fixation, although they might heal and remodel without manipulation, with no functional impairment.
- Trial name
- CASTING (NCT05736068)
- Testing
- Non-surgical treatment, Surgical treatment
- Where
- 4 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Zealand University Hospital
Colorectal Cancer, Anastomotic Leak
Quantitative ICG Fluorescence Angiography in Colorectal Surgery
Fluorescence angiography with indocyanine green (ICG-FA) has gained increased popularity in colorectal surgery to check perfusion to the newly-formed anastomotic area and decrease the rate of postoperative anastomotic leakage.
- Trial name
- QUANTICO (NCT05153954)
- Testing
- Quantitative Indocyanine Green Fluorescence Angiography
- Where
- 2 sites in Denmark
- Volunteers
- 114 people
- Sponsor
- Zealand University Hospital
Obstructive Sleep Apnea (OSA), Excessive Daytime Sleepiness
SLEEPINESS - a Search for a Biomarker of Excessive Daytime Sleepiness in Severe Obstructive Sleep Apnoea - An Explorative Study
Study aim: This study aims to use a new brainwave monitoring device that meassure brainwaves 24 hours a day to create better understanding of sleep-wake interplay as a biomarker for excessive daytime sleepiness because of…
- Trial name
- NCT06711159
- Testing
- continuous positive airway pressure
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Zealand University Hospital
Complicated Appendicitis
Per Oral Versus Intravenous Postoperative Antibiotics After Surgery for Complicated Appendicitis.
The PIPA trial is a prospective, multicentre, cluster randomized cluster crossover non-inferiority study. We aim to test whether a three-day postoperative course of per oral antibiotics is non-inferior to a three-day…
- Trial name
- PIPA (NCT04803422)
- Testing
- Antibiotic
- Where
- 2 sites in Denmark
- Volunteers
- 3,193 people
- Sponsor
- Zealand University Hospital
Inguinal Hernia, Femoral Hernia
Fibrin Glue Versus Tacked Fixation in Groin Hernia Repair (TAPP)
In this study the researchers want to compare fibrin glue versus tacked fixation in fixation of the mesh in laparoscopic groin hernia repair. The primary endpoints are early pain in the first 3 days postoperative days.
- Trial name
- NCT01000116
- Testing
- Fibrin glue, Tacks
- Where
- Denmark
- Volunteers
- 112 people
- Sponsor
- Zealand University Hospital
Inguinal Hernia, Convalescence
Pain and Convalescence After Laparoscopic Groin Hernia Repair
The investigators want to identify limiting factors for short convalescence after laparoscopic groin hernia repair. Before the operation patients are given intensive structured information about one day´s convalescence.
- Trial name
- Lap-Lyske (NCT00962338)
- Testing
- Information
- Where
- Denmark
- Volunteers
- 210 people
- Sponsor
- Zealand University Hospital
Ventral Hernia
Reoperation Rate Versus Clinical Recurrence After Ventral Hernia Repair
The risk for recurrence after ventral hernia repair is often based on reoperation rates with short follow-up rather than recurrences identified by clinical examinations.
- Trial name
- NCT01325246
- Where
- Denmark
- Volunteers
- 945 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Coronary Artery Disease
Nurse-led Sheath Insertion in Cardiac Patients
The aim of project NUSHI is to elucidate, that radial sheath insertion can be performed by nurses and physicians with the same level of comfort and safety.
- Trial name
- NUSHI (NCT05470335)
- Testing
- nurse-led sheath insertion
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- Zealand University Hospital
Stroke, Acute, Behavior
MONitoring Sedentary Behavior and Light Physical Activity in Patients With Stroke
This randomized control trial (RCT) aims to test the effect of a 12 weeks tailored behavioral intervention on stroke survivors living in the community and compare the results to a control group of stroke survivors participating…
- Conditions
- Stroke, Acute, Behavior, Physical Inactivity, Sedentary Behavior
- Trial name
- MONSS (NCT05793177)
- Testing
- Everyday Life is Rehabilitation
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Zealand University Hospital
Liver Diseases
Evaluation of Liver Disease in Individuals Attending Alcohol Abuse Treatment - a Randomized Controlled Pilot Trial
This pilot study aims to evaluate the feasibility of a non-blinded randomized controlled trial with a parallel group design of an invitation to an evaluation of liver disease (intervention) compared to standard care with no…
- Trial name
- NCT05244720
- Testing
- Fibroscan, Blood samples
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Zealand University Hospital
Pancreatic Cancer, Surgery
Examining Safety, Efficacy and Feasibility of Preoperative Propranolol in Patients With PDAC.
The IMPULS trial is a randomized, triple-blinded, placebo controlled, single center, pilot trial examining the efficacy and safety of preoperative propranolol in patients scheduled for pancreatic cancer surgery.
- Trial name
- IMPULS (NCT06145074)
- Testing
- Propranolol
- Where
- 2 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- Zealand University Hospital
Ureteral Neoplasms
Lymphadenectomy in Urothelial Carcinoma
Two out of three tumours in the upper urinary tract are located in the renal pelvis. Muscle-invasive urothelial carcinoma is probably more common among tumours in the upper urinary tract compared to tumours in the urinary…
- Trial name
- NCT02607709
- Testing
- Lymphadenectomy in conjugation with nephroureterectomy, Nephroureterectomy without lymphadenectomy
- Where
- Denmark
- Volunteers
- 366 people
- Sponsor
- Zealand University Hospital