Clinical trials: sponsored by Zhujiang Hospital
Depression
The Effect of Oral Bifidobacterium on Exogenous Creatine Absorption in Adult Subjects
The purpose of this clinical trial is to learn if Bifidobacterium has antidepressant-like effects by enhancing creatine absorption in adults.
- Trial name
- NCT06594406
- Testing
- Creatine, Bifidobacterium and creatine
- Where
- China
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Carcinoma, Hepatocellular
CT Imaging for Guiding PA-TACE for HCC
Postoperative adjuvant transarterial chemoembolization (PA-TACE) may improve survival outcomes in a subset of patients with resected hepatocellular carcinoma (HCC), reliable biomarkers for the criterion for the selection of…
- Trial name
- NCT06156748
- Testing
- postoperative adjuvant transarterial chemoembolization
- Where
- China
- Volunteers
- 1,770 people
- Sponsor
- Zhujiang Hospital
Stroke, Acute, Ischemic Stroke
The Correlation of Intracranial Artery Calcification and Outcomes of Mechanical Thrombectomy
CAIS-MT is a single-center, prospective cohort study, to evaluate the correlation between outcomes of endovascular treatment(EVT) and intracranial artery calcification(IAC) in patients with acute ischemic stroke due to large or…
- Conditions
- Stroke, Acute, Ischemic Stroke, Vascular Diseases, Central Nervous System Diseases
- Trial name
- CAIS-MT (NCT06418698)
- Where
- China
- Volunteers
- 434 people
- Sponsor
- Zhujiang Hospital
Brain Diseases, Ischemic Stroke
Interleukin-6 Receptor Inhibition for Symptomatic Intracranial Atherosclerosis
IRIS-sICAS is a multicenter, randomized, double-blind, placebo-controlled clinical trialis a multicenter, randomized, double-blind, placebo-controlled clinical trial, to assess the safety and efficacy of tocilizumab injection in…
- Conditions
- Brain Diseases, Ischemic Stroke, Ischemia, Stroke
- Trial name
- IRIS-sICAS (NCT06447701)
- Testing
- Tocilizumab, NaCl 0.9% 100ml
- Volunteers
- 486 people
- Sponsor
- Zhujiang Hospital
Arterial Aneurysm Wall Enhancement on HRMRI
Risk Assessment and Mechanism Analysis of Intracranial Multiple Aneurysm Instability Based on High-resolution Magnetic Resonance, Imaging Histology and Hemodynamics
This project proposes to establish a prospective cohort of MIA based on a preexisting multicenter MIA database and to combine multidimensional methods such as high-resolution magnetic resonance, hemodynamics, ambulatory blood…
- Trial name
- NCT06539767
- Where
- 2 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Zhujiang Hospital
Cotinine Levels, Arterial Aneurysm Wall Enhancement on HRMRI
A Study on the Correlation Between Cotinine Levels and Aneurysm Wall Enhancement on HRMRI.
This study aims to collect clinical, laboratory, and imaging data from patients with unruptured intracranial aneurysms, and collect blood or urine samples for cotinine testing.
- Trial name
- NCT06447714
- Testing
- smoke
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Hemodynamics;In-stent Stenosis;Transcranial Doppler;Intracranial Aneurysm;Flow Diverter; Prospective Cohort Study
Hemodynamic Study of In-Stent Stenosis(I) After Flow Diverter(F) Based on 3D-DSA(D) Combined With TCCD(T)
DTFI is a single-center, prospective cohort study aimed at evaluating the hemodynamics of in-stent stenosis after flow diverter implantation, seeking to identify the threshold effect of blood flow in stenosis.
- Trial name
- DTFI (NCT06448949)
- Testing
- Flow Diverter Implantation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Zhujiang Hospital
Electrolyte Disorder, Arrhythmia
Validation of the Accuracy of a Novel POCT Dry Electrolyte Analysis System in the Acute Care Setting
The goal of this study is to compare the performance of a novel Point-of-Care Testing (POCT) dry electrolyte analyzer (P1) with the Nova Stat Profile pHOx Ultra Analyzer System (Nova) in an acute care setting.
- Conditions
- Electrolyte Disorder, Arrhythmia, Stroke
- Trial name
- NCT06726460
- Testing
- Nova Stat Profile pHOx Ultra Analyzer System(Nova), Novel POCT dry electrolyte analysis system(P1)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Zhujiang Hospital
Respiratory Failure, Acid-Base Balance Disorder
Validation of the Accuracy of a Novel POCT Dry Blood Gas Analyzer in Acute Care Settings
The goal of this observational study is to validate the performance of the novel POCT dry blood gas analyzer EG-i30, against the currently widely used traditional wet blood gas analyzer, Radiometer ABL90, in acute care settings.
- Conditions
- Respiratory Failure, Acid-Base Balance Disorder, Sepsis, Shock
- Trial name
- NCT06726473
- Testing
- Wet Blood Gas Analyzer (ABL90), Dry Blood Gas Analyzer (EG-i30)
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Zhujiang Hospital
Acute Lymphoblastic Leukemia
CD19 CAR-T Cell Infusion as Consolidation Therapy in Adolescent and Adult Patients With Acute B-ALL Ineligible for Allogeneic HSCT: A Clinical Study
This clinical study investigates a novel treatment option for adolescents and adults with acute B-lymphoblastic leukemia (B-ALL).
- Trial name
- NCT07072494
- Testing
- CD19 CAR-T cells injection
- Where
- 2 sites in China
- Volunteers
- 30 people
- Sponsor
- Zhujiang Hospital
Ischemic Stroke, Acute, Ischemic Stroke
A Dose-Response Controlled Trial of Bevifibatide for Acute Ischemic Stroke
BCAIS-I is a single-center, randomized, double-blind, dose-response controlled clinical Trial, to preliminarily explore the efficacy of two different maintenance doses of bevifibatide citrate injection in improving 90-day…
- Conditions
- Ischemic Stroke, Acute, Ischemic Stroke, Cerebral Infarction, Brain Diseases
- Trial name
- BCAIS-I (NCT06712004)
- Testing
- Bevifibatide citrate injection
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhujiang Hospital
Papillomavirus Infections, Uterine Cervical Neoplasms
HPV Infection and Genital Microecology of Childbearing-age Female in China: A Cohort and Multicenter Study
The purpose of this study to access the relations between genital microecology, HPV infection and cervical intraepithelial neoplasia of childbearing-age female in China
- Conditions
- Papillomavirus Infections, Uterine Cervical Neoplasms, Sexual Transmitted Disease
- Trial name
- NCT04694495
- Testing
- 16S rRNA gene sequencing of cervical secretions
- Where
- 42 sites in China
- Volunteers
- 7,500 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Vegan Diet
Effect of Vegan Diet on Microbiome and Metabolism
The goal of this interventional study is to investigate how vegan diet affects health in healthy volunteers, Men and women ages 20 - 30 years old.
- Trial name
- NCT07003230
- Testing
- vegan and omnivorous diet
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Teaching Innovation, Medical Education
Effectiveness of Teacher-Student Interactive Immersive Mixed Reality Technology on Anatomy Education
Background: Novice surgeons often struggle to translate anatomical knowledge into clinical practice, primarily due to a lack of resources, significant variability in anatomical structures, and limited hands-on experience.
- Conditions
- Teaching Innovation, Medical Education, Anatomy Education
- Trial name
- NCT06739590
- Testing
- Learning with CT scans, Learning with 3D visualization models, Learning with 3D-MR visualization models
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Monoclonal Gammopathy, Multiple Myeloma
Multi-center Screening for Serum M Protein
This study aims to utilize a highly sensitive method for detecting M protein in serum to examine the prevalence of M protein in various age groups of individuals aged over 30 who underwent physical examinations in different…
- Conditions
- Monoclonal Gammopathy, Multiple Myeloma, M-protein
- Trial name
- NCT06750965
- Testing
- Serum M protein screening
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Monoclonal Gammopathies, Multiple Myeloma
Screening and Therapeutic Monitoring of Multiple Myeloma by MALDI-TOF MS Analysis
To provide a comprehensive MALDI-TOF mass spectrometry method for detecting, characterizing, and quantifying M-protein, and to track M-protein in a very sensitive and specific manner during patient treatment, providing a more…
- Conditions
- Monoclonal Gammopathies, Multiple Myeloma, M-protein
- Trial name
- NCT05686447
- Testing
- Observational studies, no intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Relapsed/Refractory Diffuse Large B-cell Lymphoma
Safety and Efficacy of Early Second Infusion of Axi-cel Based on ctDNA for R/R Large B - Cell Lymphoma
The goal of this clinical trial is to evaluate the efficacy and safety of early secondary infusion of CD19 CAR T-cell therapy in adults with relapsed/refractory diffuse large B-cell lymphoma (DLBCL), guided by ctDNA monitoring.
- Trial name
- NCT06902012
- Testing
- Infusion of Axicabtagene Ciloleucel
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Zhujiang Hospital
Hyperlipidemia
Observation on the Correlation Between Serum/Fecal Isoflavones, Abundance of TMA-producing Bacteria and Serum TMAO in Hyperlipidemia and Healthy Subjects
Previous studies have shown that trimethylamine N-oxide (TMAO), a gut microbiota-related metabolite, plays a significant role in the development and progression of cardiovascular disease (CVD).
- Trial name
- NCT06890780
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Artificial Intelligence (AI), Deep Learning
The Construction and Effect Verification of a Deep Learning-based Automated Semantic Segmentation Model for Medical Imaging
Hepatocellular Carcinoma(HCC) is a common disease in China, ranking as the fourth most prevalent malignant tumor and the third leading cause of cancer-related deaths in the country.
- Conditions
- Artificial Intelligence (AI), Deep Learning, Laparoscopic Surgery
- Trial name
- NCT06864702
- Testing
- Whether the patient received diagnosis and treatment at Zhujiang Hospital of Southern Medical University and retained medical images such as abdominal
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Hepatocellular Carcinoma (HCC)
Exploring the Value of Urine Proteomics-based Dynamic Surveillance for Early Recurrence After Radical Surgery for Hepatocellular Carcinoma: a Prospective Cohort Study
In this study, we explored and validated the predictive value of the longitudinal monitoring model of urinary proteomics for postoperative recurrence of hepatocellular carcinoma and the predictive value of minimal residual…
- Trial name
- NCT06861114
- Testing
- Urine proteomics
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Zhujiang Hospital