Clinical trials: sponsored by Alcon Research
Cataract, Astigmatism
AcrySof IQ Toric A-Code Post-Market Clinical Study
The purpose of this study is to clinically confirm the rotational stability of a modified AcrySof IQ toric intraocular lens (IOL) in a Japanese population.
- Trial name
- NCT03350503
- Testing
- AcrySof IQ Toric A-code IOL, Cataract surgery
- Where
- 4 sites in Japan
- Volunteers
- 125 people
- Sponsor
- Alcon Research
Comparison of 3D Visualization and Microscope for VR Surgery
Damages From Macular Grasping During Vitrectomy Comparing Traditional and 3D Microscope
Randomized, prospective, descriptive and comparative clinical study. The comparison is between a group of patients affected by macular pucker or macular hole, whose macular peeling is performed using a traditional optical…
- Trial name
- NCT05113212
- Testing
- Macular surgery with NGENUITY surgical display system, Macular surgery with standard operating microscope
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Anna Rita Daniele, MD
Contact Lens Complication, Dry Eye
Total30 Sphere Contact Lenses
The purpose of this study is to map comfort over the full wear day in established, asymptomatic, soft CL wearers who are refit in Total30 Sphere CLs.
- Trial name
- NCT05183022
- Testing
- Total30 Sphere Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cataract
Trifocal Intraocular Lens (IOL) Aberrometry Outcomes
The goal of this study is to evaluate subject outcomes and spectacle independence with intraoperative aberrometry and trifocal IOL implantation.
- Trial name
- NCT04196569
- Testing
- Alcon Trifocal and Trifocal Toric Intraocular Lenses
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Weill Medical College of Cornell University
Refractive Errors, Ametropia
Clinical Performance of Two Commercial, Daily Disposable Contact Lenses
The purpose of this study is to compare the clinical performance of DAILIES TOTAL1 ( DT1) contact lenses with Infuse contact lenses.
- Conditions
- Refractive Errors, Ametropia, Myopia
- Trial name
- NCT05010512
- Testing
- Delefilcon A contact lenses, Kalifilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Cataract, IOL
Visual Outcomes With a Trifocal IOL in Subjects With Open-angle Glaucoma
This study will examine the visual outcomes of subjects undergoing cataract surgery and minimally invasive glaucoma surgery with the implantation of a trifocal intraocular lens.
- Conditions
- Cataract, IOL, Glaucoma, Open-Angle
- Trial name
- NCT04619654
- Testing
- Cataract surgery with implantation of trifocal IOL combined with trabecular scaffold
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Vold Vision P.L.L.C
Vitrectomy
Beveled-Tip Versus(vs) Standard-Tip Vitrectomy Probe
The purpose of this study is to compare the efficiency of the new Utravit High-Speed 10000 cpm Beveled Probe to the current standard vitrector probe- Alcon (non-beveled) Ultravit 7500 cpm.
- Trial name
- NCT04076072
- Testing
- Utravit High-Speed 10000 cpm Beveled Probe, standard vitrector probe- Alcon (non-beveled) Ultravit 7500 cpm
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Refractive Errors, Ametropia
Clinical Performance of Two Daily Disposable Toric Soft Contact Lenses
The purpose of this study is to compare the clinical performance of PRECISION1™ for Astigmatism (P1fA) contact lenses with 1-DAY ACUVUE MOIST® for ASTIGMATISM (AMfA) contact lenses.
- Conditions
- Refractive Errors, Ametropia, Astigmatism
- Trial name
- NCT04908488
- Testing
- Verofilcon A toric contact lenses, Etafilcon A toric contact lenses
- Where
- 8 sites in United States
- Volunteers
- 115 people
- Sponsor
- Alcon Research
Dry Eye
Digital Device Users Who Are Treated With Systane Hydration PF
Systane Hydration PF is a recently released preservative-free artificial tear that is able to supplement the ocular surface's moisture while simultaneously soothing the eye.
- Trial name
- NCT04837807
- Testing
- Systane Hydration PF
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Myopia, Ametropia
Clinical Comparison of Two Daily Disposable Contact Lenses - Pilot Study 3
The purpose of this study is to evaluate the overall performance of PRECISION1™ contact lenses when compared to INFUSE™ contact lenses.
- Trial name
- NCT04942925
- Testing
- Verofilcon A contact lenses, Kalifilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Alcon Research
Aphakia, Corneal Astigmatism
Clinical Investigation of an AcrySof IQ PanOptix Toric Intraocular Lens
The purpose of this study is to evaluate the effectiveness and safety of the TFNT20 low cylinder power intraocular lens when implanted in the eye to replace the natural lens following cataract removal.
- Trial name
- NCT04542525
- Testing
- ACRYSOF IQ PanOptix Toric Trifocal IOL, Cataract surgery
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- Alcon Research
Macular Disease
Standard Cut Rate 27-Gauge System Versus Ultrahigh-Speed 27-Gauge System in Macular Surgery
The purpose of this study is to compare the efficiency and safety of ultrahigh-speed cut rate 27-gauge system (27+®GA HYPERVIT® Vitrectomy Probe (Alcon Laboratories, Fort Worth, TX, USA)) and standard cut rate 27-gauge vitrectomy…
- Trial name
- NCT05497128
- Testing
- Ultrahigh-speed cut rate 27-gauge system, Standard cut rate 27-gauge system
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Seoul National University Bundang Hospital
Refractive Errors
Clinical Evaluation of a Daily Wear Frequent Replacement Silicone Hydrogel Lens
The purpose of this clinical study is to demonstrate the safety and performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn in a daily wear modality.
- Trial name
- NCT03920280
- Testing
- LID015385 contact lenses, Comfilcon A soft contact lenses, CLEAR CARE
- Where
- 8 sites in United States
- Volunteers
- 120 people
- Sponsor
- Alcon Research
Refractive Errors
Clinical Comparison of Two Daily Disposable Contact Lenses
The purpose of this study is to compare the clinical performance of PRECISION1™ contact lenses to Clariti® 1 day contact lenses.
- Trial name
- NCT04865354
- Testing
- Verofilcon A contact lenses, Somofilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 170 people
- Sponsor
- Alcon Research
Cataract
Comfort Operative Ocular Light Study
Digital 3D microscopes require less light and may be more comfortable for patients requiring cataract surgery under topical anesthesia compared to conventional microscopes.
- Trial name
- COOL (NCT05085314)
- Testing
- Ngenuity digital 3D microscope, Conventional microscope
- Where
- 2 sites in France
- Volunteers
- 134 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Refractive Errors
Three Daily Wear Monthly Replacement Silicone Hydrogel Contact Lenses With Two Multi-purpose Disinfecting Solution Combinations
The purpose of this study is to evaluate corneal staining observed after 2 hours of wear with an investigational contact lens against both PureVision contact lenses pre-cycled with Biotrue and Biofinity contact lenses pre-cycled…
- Trial name
- NCT04789382
- Testing
- LID018869+RepleniSH, LID018869+Biotrue, Biofinity+RepleniSH
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Aphakia
Clinical Investigation of the AcrySof IQ Vivity Extended Vision Intraocular Lens (IOL)
The purpose of this study is to compare the visual disturbance profile of an intraocular lens (IOL) using nondiffractive optics, the VIVITY IOL, to two diffractive IOLs in subjects requiring bilateral cataract surgery.
- Trial name
- NCT04098367
- Testing
- VIVITY, SYMFONY, AT LARA
- Where
- 12 sites in Australia, New Zealand
- Volunteers
- 222 people
- Sponsor
- Alcon Research
Refractive Errors, Ametropia
Clinical Comparison of Two Daily Wear Frequent Replacement Silicone Hydrogel Soft Contact Lenses
The primary objective of this study is to evaluate the overall performance of an investigational silicone hydrogel lens when compared to ACUVUE OASYS® with HYDRACLEAR® PLUS (AOHP).
- Trial name
- NCT04532099
- Testing
- Lehfilcon A contact lenses, Senofilcon A contact lenses, Comfilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 132 people
- Sponsor
- Alcon Research
Refractive Error - Myopia Severe, Refractive Error - Myopia Simple
Early Feasibility Study of UV-Femtosecond Laser Assisted Lenticular Extraction
The purpose of this study is to evaluate the initial safety of the UV-FS laser in humans.
- Trial name
- NCT03021707
- Testing
- WaveLight® Ultraviolet Femtosecond (FS) Laser System, Laser Assisted Lenticular Extraction
- Where
- 4 sites in United States, Ireland and 1 more
- Volunteers
- 7 people
- Sponsor
- Alcon Research
Dry Eye Disease
Systane Complete Multi-symptom Relief
The purpose of this study is to demonstrate effective symptom relief with the use of Systane Complete among subjects with dry eye disease (DED).
- Trial name
- NCT05056155
- Testing
- Systane Complete
- Where
- 4 sites in United States
- Volunteers
- 119 people
- Sponsor
- Alcon Research