Clinical trials: sponsored by Rennes University Hospital
PAD - Peripheral Arterial Disease, Lumbar Spinal Stenosis
CLE-PAD : Prevalence of PAD in Patients With Surgically Lumbar Spinal Stenosis
The goal of this interventional study is to evaluate the rate of existing lower limb peripheral artery disease (PAD) in patients with surgically lumbar spinal stenosis (LSS).
- Conditions
- PAD - Peripheral Arterial Disease, Lumbar Spinal Stenosis, Lower Limb Arterial Disease
- Trial name
- CLE-PAD (NCT07469020)
- Testing
- contrast-enhanced CT scan
- Where
- 3 sites in France
- Volunteers
- 49 people
- Sponsor
- Rennes University Hospital
Cardiac Surgery
Evaluation of Preoperative Anxiety Level Based on the Day of Admission for Cardiac Surgery
Prospective, observational, non-randomized study that evaluates the impact of the admission day (J-1 vs J-0) on preoperative anxiety in cardiac surgery patients.
- Trial name
- ADMITY (NCT06794697)
- Testing
- Questionnaire including APAIS scale
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Rennes University Hospital
Prehospital Emergency, Neck Injury
IPSTRAUC : Impact on Care Pathways of a New Management of Cervical Trauma in Conscious Patients Stable in Pre-hospital Care
The aim of the study is to evaluate the application of Canadian C-Spine rules adapted to pre-hospital settings in France in order to improve the appropriateness of cervical spine immobilisation, reduce unnecessary imaging…
- Conditions
- Prehospital Emergency, Neck Injury, Neck Trauma, Emergency Medical Services
- Trial name
- IPSTRAUC (NCT06983873)
- Testing
- adapted Canadian C-Spine rules
- Where
- 14 sites in France
- Volunteers
- 840 people
- Sponsor
- Rennes University Hospital
Interprofessional Education
Impact of IPE in Multidisciplinary Primary Care Centres on Collaborative Competency of Healthcare Students (FLIRT-MSP)
The aim of our study is to evaluate the impact of interprofessional education program (IPEP) for healthcare students in clinical placement in MPCC on interprofessional collaboration (IPC), comparing the acquisition of…
- Trial name
- FLIRT-MSP (NCT06789939)
- Testing
- Train the trainer program for MPCC professionals
- Where
- 26 sites in France
- Volunteers
- 96 people
- Sponsor
- Rennes University Hospital
Self-management
Self-management Education in Multi-professional Health Centres
The goal of this observational study is to learn about the best educative and organizational dimensions favouring the development of self-management education in multiprofessional health centres.
- Trial name
- ETHOPEE (NCT05950451)
- Testing
- No intervention
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Rennes University Hospital
Stroke (CVA) or Transient Ischemic Attack, Stroke (CVA) or TIA
Trunk Impairment Scale - Adaptation and Validation in French
The objective of this project is to verify the validity and determine the clinimetric properties after translation and adaptation into French of the Trunk Impairment Scale (TIS), a scale for measuring trunk control and seated…
- Trial name
- KER-TIS fr (NCT07419087)
- Testing
- Evaluation by the TIS
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape
Age-related Macular Degeneration
Multicenter Real-life Observational Study Switched Aflibercept or Ranibizumab to Faricimab in Patients With AMD.
Age-related macular degeneration (AMD) is a degenerative retinal disease. The prognosis of the exudative form was transformed by the introduction of the anti-VEGF monoclonal antibody treatments ranibizumab [1] and aflibercept [2]…
- Trial name
- FAR-WEST (NCT06271330)
- Testing
- Faricimab
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Stroke Sequelae
Mechanisms of Balance Disorders in a Seated Position Following a Stroke
One of the causes of disability in stroke patients is postural disturbances that result in postural asymmetry in the standing position, characterized during an evaluation on a force platform by a greater displacement of the…
- Trial name
- HEMISEAT (NCT04152616)
- Testing
- Instrumental evaluation of posture
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Aging, Frailty
Evaluation of a Health Monitoring Platform for Elderly in Home Care Context
This study aims at, as a primary objective, studying acceptability of elderly about a health monitoring platform for home support and home care.
- Trial name
- ACCORDS (NCT04514536)
- Testing
- Health monitors
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Infant, Premature
Preliminary Study to the Conception of a Non-invasive Neonatal Monitoring System With Development of a Database
Each year, 300 000 new borns are hospitalised in neonatology units in Europe. This period is very sensitive as newborns are exposed to a high risk of morbidity and mortality, with severe impact on neuro-developmental prognostic.
- Trial name
- Digi-NewB (NCT02863978)
- Testing
- Multimodal signal acquisitions
- Where
- 6 sites in France
- Volunteers
- 746 people
- Sponsor
- Rennes University Hospital
Infertility, Intellectual Disability
Prospective Study to Assess Medical Performance of Optical Mapping and Long Read Sequencing in Detecting Numerical and Structural Chromosome Abnormalities
Chromosomal aberrations are major causes of developmental disorders (Intellectual disability (ID), multiple congenital anomalies (MCA), autism spectrum disorders (ASD)) as well as reproductive disorders (RD) in particular…
- Conditions
- Infertility, Intellectual Disability, Malformation, Miscarriage
- Trial name
- CHROMAPS (NCT05290051)
- Testing
- Optical Genome Mapping (Bionano®), Longread sequencing (Nanopore®)
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Metastatic Clear Cell Renal Cell Carcinoma
Validation of a Predictive Nomogram of Response or Resistance to Targeted Therapies in Metastatic Clear Cell Renal Cell Carcinoma
The purpose of this study is to validate of a predictive nomogram of response or resistance to targeted therapies in metastatic clear cell renal cell carcinoma
- Trial name
- RTKI (NCT02848768)
- Testing
- Sunitinib
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Rennes University Hospital
Lung Diseases
Phenotypic Characterization of Alveolar Macrophages 2016 (Caract-Aires-2016)
The aim of the study is to investigate by flow cytometry the phenotype of alveolar macrophages (AMs) isolated from patients with non-infectious lung diseases.
- Trial name
- Caract-Aires (NCT03250897)
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Rennes University Hospital
Digestive System Diseases, Inflammatory Bowel Disease, Ulcerative Colitis Type
Intestinal Organoids
Over the last decade, the use of mini-organ or organoids has been increasingly developed in fundamental research. Indeed, digestive organoids represent an essential advance compared to classical culture systems (epithelial cell…
- Conditions
- Digestive System Diseases, Inflammatory Bowel Disease, Ulcerative Colitis Type, Crohn Disease
- Trial name
- BIOÏDES (NCT05294107)
- Testing
- additional biopsies
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Rennes University Hospital
Liver Transplantation, Acute Kidney Injury
Influence of Human Albumin Supplementation on Kidney Dysfunction After Liver Transplantation
To verify whether albumin administration to achieve serum concentration above 30g/L (treated group) and its maintenance within plasmatic physiologic range (above 30 g/L) for five days diminishes rate of AKI at Day 7 after liver…
- Trial name
- HALT (NCT06535945)
- Testing
- Albumin administration
- Where
- 8 sites in France
- Volunteers
- 400 people
- Sponsor
- Rennes University Hospital
Neurological Diseases, Central Nervous System
Rapid Declarative Neocortical Declarative Learning in Aging and Memory Diseases (ANéRAVIMM)
Learning a person's name, new words, or simply remembering where the last conversation with a friend was held are examples of associative memory, frequently disturbed in brain pathologies, but also by aging.
- Trial name
- ANéRAVIMM (NCT04846764)
- Testing
- Neuropsychological tests
- Where
- France
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Oocyte Retrieval, Local Anaesthesia
Assessment of the Influence of the Virtual Reality Headset on Pain and Anxiety During Oocyte Retrieval Under Local Anesthesia
Medically Assisted Reproduction provides help to infertile couples, single women and couples of women with a pregnancy project, and to women who wish to preserve their gametes.
- Conditions
- Oocyte Retrieval, Local Anaesthesia, Virtual Reality
- Trial name
- OVOREV (NCT05528497)
- Testing
- VR+
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Rennes University Hospital
Alzheimer Disease, Early Onset
MIMA Pilot Study: MIcrostructure of the Medial Temporal Lobe in Early Alzheimer's Disease
Patients with Mild Cognitive Impairment (MCI) or Subjective Cognitive Decline (SCD) may or may not develop Alzheimer's disease (AD) dementia.
- Trial name
- MIMA-P (NCT06099587)
- Testing
- high-resolution diffusion MRI
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Nursing Homes, Clinical Trial
MAÏA - MAintain the Level of Independence Through Alimentation
Malnutrition has serious consequences: increased risk of falls, hospitalization and mortality. Malnutrition may accompany or aggravate another geriatric syndrome.
- Conditions
- Nursing Homes, Clinical Trial, Food
- Trial name
- MAÏA (NCT05628155)
- Testing
- Oral diet including n-3 PUFA intake
- Where
- France
- Volunteers
- 315 people
- Sponsor
- Rennes University Hospital
Sleep Apnea Syndrome, Obstructive
Treatment Failure of Continuous Positive Airway Pressure (CPAP) in Patients With Obstructive Sleep Apnea Syndrome (OSA): A Trial Comparing Polysomnography and the Sunrise Device to Drive Treatment-Adjustment Decisions.
The goal of this clinical trial is to determine whether treatment-adjustment decisions based on one night of home monitoring with the Sunrise device are comparable to decisions based on one night of in-laboratory polysomnography…
- Trial name
- SUNCPAP (NCT07530302)
- Testing
- Sunrise
- Where
- France
- Volunteers
- 105 people
- Sponsor
- University Hospital, Grenoble