Clinical trials: sponsored by University of Bern
Chronic Hepatitis C
High Dose Ribavirin in the Treatment of Chronic Hepatitis C
Treatment of patients with chronic hepatitis C infected with genotype 1 hepatitis C virus (HCV) consists of combined peginterferon/ribavirin for 48 weeks.
- Trial name
- NCT00944684
- Testing
- High ribavirin dose, Standard ribavirin dose
- Where
- 5 sites in Switzerland
- Volunteers
- 32 people
- Sponsor
- University of Bern
Stroke, Transient Ischemic Attack
Copeptin for Risk Stratification in Acute Stroke Patients: the CoRisk Study
Prospective observational multicenter study to evaluate copeptin as a prognostic marker in patients with an acute cerebrovascular event.
- Trial name
- CoRisk (NCT00878813)
- Testing
- Sampling of 15ml blood, Blood-Sampling
- Where
- 4 sites in Germany, Switzerland
- Volunteers
- 1,102 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Low Back Pain
Spinal Manipulative Therapy for Low Back Pain
Context: Acute low back pain (LBP) is a common reason for consultations in primary care. Reducing the pain in the first hours and days and restoring the functional capacity of the lumbar spine may result in a decrease in medical…
- Trial name
- NCT00294229
- Testing
- manipulative therapy
- Where
- Switzerland
- Volunteers
- 104 people
- Sponsor
- University of Bern
Sleep Disorders
Patient Preference, Sleep Quality, and Anxiety/Depression: A Randomized Comparison of Etravirine and Efavirenz
Efavirenz causes neuropsychiatric side effects and sleep disturbance, including vivid dreams, dizziness, and abnormal tiredness.
- Trial name
- SWITCH-EE (NCT00792584)
- Testing
- etravirine, efavirenz
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Geneva
Neoplasm, Hepatic, Pancreatic Neoplasms
Impact of Microparticles on Postoperative Complications in Surgical Patients
Microparticles are cellular fragments which are released actively or passively under conditions of inflammation and stress. The impact of surgical operations on quantity and quality of microparticles remains unknown.
- Conditions
- Neoplasm, Hepatic, Pancreatic Neoplasms, Colorectal Neoplasms
- Trial name
- NCT00677781
- Where
- Switzerland
- Volunteers
- 108 people
- Sponsor
- University of Bern
Primary Prevention, Stress
Efficacy of Taiji Training as a Program for Stress Prevention
Background: Excessive exposure to psychosocial stress can be a potent trigger for somatic diseases and psychological disorders, a cause for missing work, and eventually lead to high economic loss.
- Conditions
- Primary Prevention, Stress, Tai ji, Adult
- Trial name
- NCT01122706
- Testing
- Taiji training
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Bern
Women With Vulvar Intraephitelial Neoplasia or Vulvar Cancer
A New Patient Reported Outcome Instrument to Assess Symptom Experience in Women With Vulvar Neoplasms (WOMAN-PRO)
Post-surgery complications in women with vulvar neoplasms (vulvar intraepithelial neoplasia and vulvar cancer) are still high and an instrument assessing patients self-reported post-vulval surgery symptom experiences is missing.
- Trial name
- WOMAN-PRO (NCT01300663)
- Where
- 8 sites in Germany, Switzerland
- Volunteers
- 150 people
- Sponsor
- University of Basel
Myocardial Ischemia, Exercise
Exercise-induced Changes in Cardiac Function & Morphology
Until now it has been assumed that regular endurance training has a positive influence on cardiac function and that the positive effect increases with increasing intensity.
- Conditions
- Myocardial Ischemia, Exercise, Myocardial Contraction, Myocardial Stunning
- Trial name
- NCT01179802
- Testing
- Strenuous Endurance exercise
- Where
- Switzerland
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hepatocellular Carcinoma
Sorafenib With TACE to Treat Hepatocellular Carcinoma
The purpose of this study is to determine the feasibility to combine sorafenib with transarterial chemoembolisation in patients suffering from hepatocellular carcinoma.The hypothesis is that sorafenib may prevent the development…
- Trial name
- S-TACE (NCT00478374)
- Testing
- Sorafenib, Transarterial chemoembolisation with doxorubicin
- Where
- Switzerland
- Volunteers
- 21 people
- Sponsor
- University of Bern
Sleep Disorders, HIV Infections
Patient Preference, Sleep Quality, and Anxiety/Depression: A Comparison of Raltegravir and Efavirenz
Efavirenz causes neuropsychiatric side effects and sleep disturbance, including vivid dreams, dizziness, and abnormal tiredness.
- Trial name
- Switch-ER (NCT00944957)
- Testing
- Raltegravir for the first 2 weeks, Efavirenz for the last 2 weeks, Efavirenz for the first 2 weeks
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Geneva
Eosinophilic Esophagitis, Esophageal Stenosis
Eosinophilic Esophagitis: Influence of Dilation on Dysphagia and Inflammation
A database analysis and review of histological slides (retrospective) and a patient questionnaire analysis (prospective) will be conducted in Bern (Switzerland) to evaluate the efficacy and safety of esophageal dilation and its…
- Conditions
- Eosinophilic Esophagitis, Esophageal Stenosis, Esophageal Dilation, Esophageal Dilatation
- Trial name
- NCT00667524
- Where
- Switzerland
- Volunteers
- 207 people
- Sponsor
- University of Bern
Aortic Regurgitation
Diastolic Dysfunction in Aortic Regurgitation
Follow-up study in patients with severe aortic regurgitation after successful valve replacement. Systolic and diastolic function were assessed and persistent diastolic dysfunction was observed late (7-10 years) after operation.
- Trial name
- NCT00976625
- Testing
- Aortic Valve Replacement
- Where
- Switzerland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Bern
Carpal Tunnel Syndrome
Sonographic Follow-up of Patients With Carpal Tunnel Syndrome Undergoing Surgical or Conservative Treatment
In wrists with carpal tunnel syndrome (CTS) the sonographically measured largest cross-sectional area (CSA) of the median nerve is increased.
- Trial name
- CTS (NCT00694265)
- Testing
- Decompression, Conservative treatment
- Where
- Switzerland
- Volunteers
- 55 people
- Sponsor
- University of Bern
Dermatitis, Atopic
Immunopharmacological Effects of Rituximab in Atopic Dermatitis
Protocol Title: Immunopharmacological effects of Rituximab in atopic dermatitis Study Phase: Investigator driven study Study Design: Open-label, single center.
- Trial name
- NCT00267826
- Testing
- Rituximab
- Where
- Switzerland
- Volunteers
- 6 people
- Sponsor
- University of Bern
Liver Injury
Non-Operative Management of High Grade Blunt Hepatic Injury: Clinical Complications and the Role of Collateral Damage
Little is known about the role of collateral damage in patients with high grade liver injuries (LI). This retrospective single centre study investigates the safety of the non-operative management of patients with high grade blunt…
- Trial name
- NOMLI (NCT00694499)
- Where
- Switzerland
- Volunteers
- 183 people
- Sponsor
- University of Bern
Thyroid Surgery for Benign Disease
Steroid Before Thyroidectomy
We evaluated the effects of giving a single dose of steroid before thyroid surgery in a single institutional, double-blinded, randomized controlled trial.
- Trial name
- NCT00619086
- Testing
- Dexamethason Helvepharm ®
- Where
- Switzerland
- Volunteers
- 72 people
- Sponsor
- University of Bern
Coronary Heart Disease
Sirolimus-Eluting Versus Paclitaxel-Eluting Stents for Coronary Revascularization
Context: Sirolimus-eluting stents and paclitaxel-eluting stents, as compared with bare-metal stents, reduce the risk of restenosis.
- Trial name
- NCT00297661
- Testing
- Sirolimus-eluting stent, Paclitaxel-eluting stent
- Where
- Switzerland
- Volunteers
- 1,012 people
- Sponsor
- University of Bern
Arterial Occlusive Diseases
Rio Trial - ReoPro and Peripheral Arterial Intervention to Improve Clinical Outcome in Patients With Peripheral Arterial Disease
The Rio Study is a randomized, double blinded German- Swiss- Austria multi-centre trial on the efficacy and safety of ReoPro together with interventional recanalization of TASC D lesions in the SFA and popliteal artery.
- Trial name
- NCT00156611
- Testing
- Balloon Angioplasty, ReoPro
- Where
- Germany
- Volunteers
- 420 people
- Sponsor
- University Hospital Tuebingen