Clinical trials: sponsored by Emory University
Pediatric Cancer
Distress in the Pediatric Oncology Setting: Intervention Versus Natural Adaptation
Children with cancer undergo many procedures as part of their treatment, and are often hospitalized or have frequent clinic visits, which can be distressing.
- Trial name
- MSAD (NCT04409301)
- Testing
- My Special Aflac Duck (MSAD), Standard of care control
- Where
- 8 sites in United States
- Volunteers
- 160 people
- Sponsor
- Emory University
Social Emotional Learning
Learning for Hearts and Minds in Elementary School
ABSTRACT- Introduction: Skills such as recognizing and managing emotions, developing empathy, building cooperative relationships, solving problems effectively and obtaining communication skills have gained importance in several…
- Trial name
- NCT06174467
- Testing
- SEELearning Training, Waiting list group of the intervention
- Where
- Brazil
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Patellofemoral Pain Syndrome, Patellofemoral Pain
Neural Correlates of Knee Sensorimotor Control in Patients With Patellofemoral Pain Syndrome
This study aims to determine the neural correlates of knee motor control in young females with patellofemoral pain (PFP). Each participant will attend a single study visit which may last up to 3 hours.
- Trial name
- NCT04099004
- Testing
- Neural Imaging
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Emory University
Cystic Fibrosis, Dysbiosis
Vitamin D and Prebiotics for Intestinal Health in Cystic Fibrosis
The study will assess if administration of high-dose vitamin D and a commonly used prebiotic (inulin) is effective to reduce gastrointestinal dysbiosis and to improve critical intestinal functions in Cystic Fibrosis with the…
- Trial name
- NCT04118010
- Testing
- Vitamin D3, Inulin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Emory University
Metastatic Colorectal Cancer, Colorectal Adenocarcinoma
Durvalumab Plus CV301 With Maintenance Chemotherapy in Metastatic Colorectal or Pancreatic Adenocarcinoma
This is a dual arm, open label phase I/II study to evaluate the safety and clinical activity of the combination of durvalumab with CV301 in combination with maintenance chemotherapy for patients with metastatic colorectal or…
- Conditions
- Metastatic Colorectal Cancer, Colorectal Adenocarcinoma, Pancreatic Adenocarcinoma, Metastatic Pancreatic Cancer
- Trial name
- NCT03376659
- Testing
- Durvalumab, CV301, Capecitabine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Georgetown University
HIV/AIDS
Implementation of Rapid HIV Self-Testing Among MSM Project
This study will use online materials and strategies to recruit 3600 Black and Hispanic men who have sex with men (MSM) and transgender women (TGW) to participate in a study evaluating the effectiveness of the Know@Home mobile app…
- Trial name
- iSTAMP (NCT04219878)
- Testing
- Know@Home, Self-test Kit
- Where
- United States
- Volunteers
- 2,195 people
- Sponsor
- Emory University
Encopresis, Autism Spectrum Disorder
Treatment of Encopresis in Children With Autism Spectrum Disorders
This study is comparing a multidisciplinary intervention for encopresis (MIE), consisting of both medical and behavioral components to treatment as usual control (TAU).
- Trial name
- NCT03197922
- Testing
- MIE Treatment, Glycerin Suppository, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Emory University
Influenza
Bone Marrow and Peripheral Blood Immune Responses Study
The purpose of this study is to evaluate the immune response of the killed flu vaccine in healthy subjects. Participants in this study are considered to be healthy volunteers.
- Trial name
- NCT05616546
- Testing
- Influenza Vaccine
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Emory University
Skin Lesion
Ultrasound in Diagnosing Patients With Skin Lesions
This trial studies the use of a novel non-invasive ultrasound technique in diagnosing patents with skin lesions. Diagnostic procedures, such as ultrasound, may be a less invasive way to check skin lesions for skin cancer and…
- Trial name
- NCT03914846
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Emory University
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma
Radioembolization of Metastatic Breast Cancer to the Liver as a 2nd/3rd Line Therapy
This phase II trial studies the effects of radioembolization with yttrium Y-90 works as a 2nd or 3rd line therapy for treating patients with breast cancer that has spread to the liver (metastatic to the liver).
- Conditions
- Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Metastatic Carcinoma in the Liver, Prognostic Stage IV Breast Cancer AJCC v8
- Trial name
- NCT05315687
- Testing
- Y-90 SIR-Spheres, Yttrium-90 Microsphere Radioembolization, Systemic Therapy
- Where
- United States
- Sponsor
- Emory University
Hemophilia A
Emicizumab PUPs and Nuwiq ITI Study
This study prospectively investigates the safety, FVIII immunogenicity, and hemostatic efficacy of prophylactic HEMLIBRA® given with a concomitant low dose recombinant factor VIII (rFVIII) known as NUWIQ®, in HA infants and…
- Trial name
- NCT04030052
- Testing
- Nuwiq (low dose protocol), HEMLIBRA, Nuwiq (Atlanta protocol)
- Where
- 8 sites in United States
- Sponsor
- Emory University
Alzheimer Disease, Dementia
Harmony at Home: A Pilot Telehealth Program for Rural ADRD Caregivers
There is a need for caregiver-initiated and -implemented non-pharmacological interventions directly to and for the person with dementia, including environmental assessment and modification, as first-line treatments for behavioral…
- Conditions
- Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases
- Trial name
- NCT05202223
- Testing
- Harmony at HOME (H@H)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Elizabeth K Rhodus
Major Depression
Bupropion Versus Escitalopram on Reward Circuitry and Motivational Deficits
This study is designed to determine whether bupropion (vs escitalopram) increases functional connectivity (FC) within reward-related neurocircuits and decreases motivational deficits in depressed patients with increased…
- Trial name
- NCT04352101
- Testing
- Bupropion XL, Escitalopram
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Emory University
Resectable Intrahepatic Cholangiocarcinoma, Stage 0 Intrahepatic Cholangiocarcinoma AJCC v8
Preoperative Nab-paclitaxel, Cisplatin, and Gemcitabine Chemotherapy With or Without Infigratinib Targeted Therapy for the Treatment of Resectable Intrahepatic Cholangiocarcinoma, The OPTIC Trial
This phase II trial assesses the feasibility (including both safety and tolerability) of conducting Next Generation Sequencing and administering targeted therapy (infigratinib) in the preoperative setting for patients with…
- Conditions
- Resectable Intrahepatic Cholangiocarcinoma, Stage 0 Intrahepatic Cholangiocarcinoma AJCC v8, Stage I Intrahepatic Cholangiocarcinoma AJCC v8, Stage II Intrahepatic Cholangiocarcinoma AJCC v8
- Trial name
- NCT05514912
- Testing
- Cisplatin, Gemcitabine Hydrochloride, Infigratinib Phosphate
- Sponsor
- Emory University
Drug Use, Peer Influence
The Peer-Based Retention of People Who Use Drugs in Rural Research
The purpose of this study is to, through several aims, test the effectiveness of peer-driven intervention and inform methods to optimize engagement in research in people who use drugs (PWUD) in rural America.
- Trial name
- PROUD-R2 (NCT03885024)
- Testing
- Retention Video
- Where
- 3 sites in United States
- Volunteers
- 850 people
- Sponsor
- Oregon Health and Science University
Substance Use, HIV Infections
Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)
This study will test the effects of an intervention to reduce substance use and related harms among people leaving rural jails or otherwise involved in the criminal justice system.
- Conditions
- Substance Use, HIV Infections, HCV Infection, Sexually Transmitted Infections (Not HIV or Hepatitis)
- Trial name
- NCT04134767
- Testing
- Health Linkage, Overdose Education
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- April M Young
Chemotherapy Effect
Evaluation of a Mobile App to Promote Social Support for Oncology Patients
Our study will evaluate patient and caregiver use of a new mobile application (app) to support patients undergoing chemotherapy treatment for cancer.
- Trial name
- NCT04331678
- Testing
- Comparator App
- Where
- 3 sites in United States
- Volunteers
- 230 people
- Sponsor
- West Cancer Center
Chronic Heart Failure
Cost and Shared Decision-Making for Heart Failure
This study is designed to understand the impact of providing patient-specific cost at the time of the clinical encounter on decision-making for heart failure medications.
- Trial name
- NCT04793880
- Testing
- Medication Cost Information, Heart Failure Medicines Checklist
- Where
- 4 sites in United States
- Volunteers
- 247 people
- Sponsor
- Emory University
Brain Injuries, Traumatic, Concussion, Brain
Longitudinal Assessment of Post-concussion Driving in Young Adults
Upwards of 3.8 million concussions occur annually in the United States. Driving is a highly complicated activity that requires visual, motor, and cognitive skills, which are commonly impaired after concussion.
- Conditions
- Brain Injuries, Traumatic, Concussion, Brain, Brain Injury Traumatic Mild
- Trial name
- LAPDYA (NCT05942638)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Georgia
Sickle Cell Disease
iCanCope With Sickle Cell Pain
The project will test a tailored web and smartphone-based application (iCanCope with SCD) to improve pain self-management and functioning in youth (aged 12-18) with sickle cell disease.
- Trial name
- NCT03201874
- Testing
- Pain self-management, Education
- Where
- 4 sites in United States, Canada
- Volunteers
- 137 people
- Sponsor
- Seattle Children's Hospital
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