Clinical trials: sponsored by Assiut University
Postoperative Acute Kidney Injury
Processed Electroencephalography-guided General Anesthesia and Outcomes in Major Abdominal Surgery
This study aims to evaluate whether the reduction in the amount of intraoperative norepinephrine required to prevent hypotension, facilitated by processed electroencephalography (pEEG) -guided general anesthesia, will lead to a…
- Trial name
- NCT06753409
- Testing
- Processed electroencephalography (pEEG) Guided General Anesthesia, Non-pEEG-Guided General Anesthesia (with blinded pEEG monitoring)
- Where
- Egypt
- Volunteers
- 162 people
- Sponsor
- Assiut University
Acute Kidney Injury Due to Sepsis
Hemodynamic Resuscitation Guided by Non-Invasive Mean Systemic Filling Pressure to Prevent Acute Kidney Injury in Septic Shock
The goal of this clinical trial is to evaluate the efficacy of a hemodynamic resuscitation protocol guided by the Venous Return Gradient (Pmsf - CVP), measured via the non-invasive arm cuff technique, in reducing the incidence of…
- Trial name
- NCT07481097
- Testing
- Hemodynamic measurements during reduction in Norepinephrine and fluid boli.
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Stage III Periodontitis
Injectable Platelet-Rich Fibrin (i-PRF) and Oxygen-Releasing Gel in the Treatment of Stage II Periodontitis.
Periodontitis is a chronic multifactorial inflammatory disorder affecting the periodontium, often implicated with microbial dysbiosis.
- Trial name
- NCT07859358
- Testing
- Injectable Platelet-Rich Fibrin (i-PRF, Peroxoborate Oxygen-Releasing Oral Gel, Sterile 0.9% Saline Solution
- Where
- 2 sites in Egypt
- Volunteers
- 24 people
- Sponsor
- Assiut University
Laparoscopic Cholecystectomy
Adding Magnesium Sulfate or Dexmedetomidine to Bupivacaine in Oblique Subcostal Tap Block for Laparoscopic Cholecystectomy: A Randomized Double -Blind Controlled Study
Laparoscopic cholecystectomy (LC) is one of the commonly performed surgical procedures associated with a moderate degree of postoperative pain especially on the 1st postoperative day.
- Trial name
- NCT06743919
- Testing
- Magnesium sulfate 50% - 1g/h, dexmedetomidine 0.5 µg/kg IV, Bupivacaine
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Assiut University
Lifestyle Behaviors
Lifestyle Behaviors and Their Associations With Mental Health, Aggressive Behaviors and Academic Performance Among Assiut University Students
To promote the health and well-being of Assiut University students and promote healthy lifestyle, health-related behaviors and sleep quality.
- Trial name
- NCT07879248
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- Assiut University
Tuberculosis
KAP Regarding Tuberculosis Among Physicians in Assiut City
To Strengthen tuberculosis education and awareness among physicians in Assiut city in the framework of national tuberculosis control program.
- Trial name
- NCT05805878
- Where
- Egypt
- Volunteers
- 296 people
- Sponsor
- Assiut University
Right Ventricular Dysfunction
Evaluation of Right Ventricular Function Post Mitral Valve Operations
We aim to determine the function of Right ventricle post mitral valve surgeries in patients with pulmonary hypertension using transthoracic echocardiography3- and 6-months post-operatively to detect the effect of mitral valve…
- Trial name
- NCT05620992
- Testing
- Echocardiography
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Post-Traumatic Subarachnoid Hemorrhage
Superior Cervical Sympathetic Block Versus Stellate Ganglion Block in Post-traumatic Subarachnoid Hemorrhage
Posttraumatic Subarachnoid hemorrhage (SAH) is a life-threatening neurological problem with a high mortality rate. Delayed cerebral ischemia (DCI) is the second-leading cause of death and disability in patients suffering from…
- Trial name
- NCT06134583
- Testing
- Superior cervical sympathetic block group, Stellate ganglion block group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Cardiac Surgeries
Early Cardiopulmonary Rehabilitation Bundle Functional Capacity and Outcomes of Cardiac Surgeries Patients
The goal of this quasi-experimental study is to evaluate the impact of Early. Cardiopulmonary Rehabilitation Bundle on Functional Capacity and Outcomes in Cardiac Surgeries Patients The main question is Patients receive early…
- Trial name
- NCT07724353
- Testing
- Early cardiopulmonary rehabilitation bundle
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gallstones, Pain
Comparison of the Efficacy of Different Analgesic Strategies for Pain Control After Laparoscopic Cholecystectomy (LC)
The investigators collected 200 patients underwent safe uncomplicated laparoscopic cholecystectomy, then different strategies of pain control are used.
- Trial name
- Randomized (NCT07897435)
- Testing
- Low pneumoperitoneum, Local anaesthetic instillation to gallbladder bed
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Leukemia
Glycemic Control in Leukemia Patients
Glycemic control in leukemia patients
- Trial name
- NCT07898488
- Volunteers
- 54 people
- Sponsor
- Assiut University
Chronic Total Occlusion (CTO), Frontal QRS-T Angle
Relationship Between Frontal QRS-T Angle and Collateral Circulation in Coronary Artery Chronic Total Occlusion
Aim of the work: To examine the relationship between collateral circulation and the frontal QRS-T angle in patients with chronic total occlusion (CTO)
- Trial name
- NCT07743437
- Testing
- 12-lead Electrocardiogram (ECG) and Coronary Angiography
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Spinal Cord Ischemia
Risk Factors for Spinal Cord Injury After Minimally Invasive Aortic Repair
This study aims to identify factors linked to spinal cord injury after aortic repair. The aorta is the body's main artery. The repairs studied use a fabric-covered tube, called a stent graft, placed inside the aorta.
- Trial name
- SCI-AORTA (NCT07896564)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Bronchiectasis, Sleep-Disordered Breathing
Sleep Quality in Patients With Non-cystic Fibrosis Bronchiectasis
Non-cystic fibrosis (non-CF) bronchiectasis is a chronic, heterogeneous airway disease characterized by irreversible bronchial dilatation, persistent airway infection, and neutrophilic inflammation that together drive daily…
- Trial name
- NCT07147803
- Testing
- Pittsburgh Sleep Quality Index
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
MRI in Evaluation of Fecal Incontinence
Fecal Incontinence (FI) is a Debilitating Physical and Psychological Disorder Characterizedbytheinvoluntary Loss of Flatus or Liquid/Solid Stool.
Fecal incontinence (FI) is a debilitating physical and psychological disorder characterizedbytheinvoluntary loss of flatus or liquid/solid stool.
- Trial name
- NCT07898748
- Testing
- 3DendoanalultrasoundversusexternalphasedarrayMRI inevaluationoffecal Incontinence
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cervical Intraepithelial Neoplasia, Uterine Cervical Neoplasms
Clinical Audit of Cervical Cytology Services in an Early Cancer Detection Unit
Cervical cancer is largely preventable when precancerous changes are detected and treated early. However, an effective screening program requires not only collecting a screening test, but also ensuring seamless continuity across…
- Conditions
- Cervical Intraepithelial Neoplasia, Uterine Cervical Neoplasms, Cervical Precancerous Lesions, Cervical Dysplasia
- Trial name
- NCT07897786
- Volunteers
- 500 people
- Sponsor
- Assiut University
Respiratory Insufficiency, Wounds and Injuries
Humidification Effects on Airway Complications and Clinical Outcomes in Trauma ICU Patients on Mechanical Ventilation
This study compares the effects of two primary airway humidification methods-active heated humidifiers (HHs) and passive heat-and-moisture exchangers (HMEs)-on trauma intensive care unit (ICU) patients requiring prolonged…
- Conditions
- Respiratory Insufficiency, Wounds and Injuries, Critical Illness
- Trial name
- NCT07713238
- Testing
- Airway Humidification Device
- Where
- Egypt
- Volunteers
- 162 people
- Sponsor
- Assiut University
Intra-Bony Defects in Periodontitis Patients
The Efficacy of Exosomes Combined With Synthetic Bone Graft for the Treatment of Periodontal Intra-bony Defects
The aim of this study will be to evaluate clinically, radiographically and biochemically the efficacy of exosomes combined with synthetic bone graft for the treatment of periodontal intra-bony defects.
- Trial name
- NCT07897292
- Testing
- single flap approach, single flap approach combined with nanocrystalline hydroxyapatite bone substitute, Exosomes
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Khoshoe Al-mokhtar Mohammed
Rheumatoid Arthritis
Efficacy of JAK STAT Pathways Inhibitors in Treatment of Patients With Rheumatoid Arthritis
There is no treatment that could utterly cure Rheumatoid arthritis (RA), but the disease is mainly improved by conventional disease-modifying anti rheumatic drugs.
- Trial name
- NCT05788705
- Testing
- Green Tea Polyphenolics (EGCG), Chamomile (Matricaria recutita), Licorice
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Adel A.Gomaa
Critical Illness, Hyperglycemia
Stress Hyperglycemia Ratio and Glucose Variability in Critically Ill Patients
This prospective cohort study aims to evaluate the stress hyperglycemia ratio and glucose variability among critically ill patients admitted to the intensive care unit.
- Trial name
- NCT07892222
- Volunteers
- 75 people
- Sponsor
- Assiut University
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