Clinical trials: sponsored by Linkoeping University
Crowding of Teeth, Malocclusion; Displaced Teeth
Timing, Trajectories and Prediction in Severe Dental Crowding: The Create SPACE (cSPACE)
Dental crowding is the most common malocclusion affecting up to 45% of the population and represents one of the leading reasons for seeking orthodontic treatment.
- Conditions
- Crowding of Teeth, Malocclusion; Displaced Teeth, Malocclusion in Children
- Trial name
- cSPACE (NCT07911176)
- Testing
- Early first premolar extraction with observation, Early first premolar extraction with planned fixed orthodontic treatment
- Volunteers
- 300 people
- Sponsor
- Vastra Gotaland Region
Thoracolumbar Burst Fracture
StUdy oN Burst Fractures (SunBurst)
Thoracolumbar (TL) burst fractures are seen in all ages and usually associated with high-energy trauma. Treatment include both surgical and non-surgical options.
- Trial name
- SunBurst (NCT05003180)
- Testing
- Surgical stabilization
- Where
- 17 sites in Norway, Sweden
- Volunteers
- 202 people
- Sponsor
- Uppsala University
RSI, Rapid Sequence Induction
RSI Observation Follow-up
The purpose of this prospective observational study is to determine if compliance to local guildelines for the RSI procedure, after introduction of a RSI-check list, persists over time (36-60months).
- Conditions
- RSI, Rapid Sequence Induction, Complication of Anesthesia, Compliant Behavior
- Trial name
- NCT05775029
- Where
- 2 sites in Sweden
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Jakob Zeuchner
Cancer
Feasibility Study of a Co-Designed Gamified Medical Yoga App for Home-Based Cancer Rehabilitation
The project aims to develop a gamified medical yoga intervention through co-design with patients with cancer and key stakeholders, ensuring alignment with user needs and requirements.
- Trial name
- NCT07872956
- Testing
- Medical yoga
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Linkoeping University
Hypercholesterolemia, Familial, Clinical Decision Support
Clinical Decision Support for Familial Hypercholesterolemia
A cluster randomized study in the primary care setting to evaluate a computer-based clinical decision support system to aid in the identification and management of patients with FH.
- Trial name
- CDS-FH (NCT03989167)
- Testing
- Clinical decision support
- Where
- Sweden
- Volunteers
- 472,029 people
- Sponsor
- University Hospital, Linkoeping
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Cirrhosis
MASLD in Type 2 Diabetes in Primary Care - a Follow-up Study
The goal of this observational study is to understand how metabolic dysfunction-associated steatotic liver disease (MASLD) changes over time in individuals with type 2 diabetes who previously participated in the EPSONIP study.
- Conditions
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Cirrhosis, Advanced Fibrosis, Sarcopenia
- Trial name
- EPSOMIP2 (NCT07312136)
- Where
- Sweden
- Volunteers
- 317 people
- Sponsor
- Linkoeping University
Atrial Fibrillation (AF), Atrial Fibrillation Ablation
Catheter Ablation vs Conservative Care in Elderly Patients With Atrial Fibrillation
ACE-AF is a multicenter randomized study in people aged 78 years and older with symptomatic atrial fibrillation (AF). AF is a common heart rhythm disorder in older adults and can cause reduced quality of life and lead to serious…
- Conditions
- Atrial Fibrillation (AF), Atrial Fibrillation Ablation, Elderly
- Trial name
- ACE-AF (NCT07424690)
- Testing
- Catheter Ablation for Atrial Fibrillation, Optimized Medical Therapy for Atrial Fibrillation, Implantable Loop Recorder (ILR)
- Where
- 2 sites in Sweden
- Volunteers
- 282 people
- Sponsor
- Karolinska University Hospital
Diverticulitis Colon
Scandinavian Diverticulitis Trial SCANDIV-II
This study focuses on the treatment for complicated diverticulitis classified as Hinchey I-IV. The aim of this prospective observational study is to evaluate type of treatment and the success rate of treatment in acute…
- Trial name
- SCANDIV-II (NCT04254224)
- Testing
- colon resection, stoma
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Uppsala University
Work-Related Musculoskeletal Disorders
Reducing Physical Workload Among Assistant Nurses Through Ergonomic Work Technique Training With or Without Biofeedback
Assistant nurses often develop work-related pain in the back, neck and shoulders because their work involves frequent patient handling and movement.
- Trial name
- HUMLA (NCT07805629)
- Testing
- Group A. Patient handling and movement training, Group B: Patient handling and movement training plus biofeedback
- Volunteers
- 60 people
- Sponsor
- Linkoeping University
Cardiac Arrest (CA)
Effects of a Web-based Support Programme for Cardiac Arrest Survivors
The overall goal of this clinical trial is to learn if a web-based support programme can improve wellbeing in cardiac arrest survivors by helping them manage emotional, cognitive, and physical challenges.
- Trial name
- CARDIS (NCT07240714)
- Testing
- Digital Support Programme
- Where
- 9 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Linkoeping University
Osteoporosis
Patient Education in Osteoporosis (RCT-PATOS)
The objective of this randomized clinical trial is to assess both the effectiveness and underlying mechanisms of patient education for individuals aged 50 years and older with osteoporosis.
- Trial name
- RCT-PATOS (NCT07367776)
- Testing
- Digital patient education, Face-to-face patient education, General information on osteoporosis (open website)
- Where
- 7 sites in Sweden
- Volunteers
- 600 people
- Sponsor
- University Hospital, Linkoeping
Cervical Radiculopathy
Functioning in Individuals With Cervical Radiculopathy After Posterior Cervical Decompression
Compression on structures, as spinal nerves, in the cervical spine can cause cervical radiculopathy which leads to pain, disability, and reduced quality of life for the affected individual.
- Trial name
- NCT05310578
- Testing
- Posterior cervical foraminotomy (with our without laminectomy)
- Where
- 3 sites in Sweden
- Volunteers
- 154 people
- Sponsor
- Linkoeping University
Myocardial Infarction, Frailty
Management and Outcomes of Patients Admitted to Coronary Care Units, Depending on Degree of Frailty and Comorbidities
Background Patients less than 80 years of age, who suffer a myocardial infarction (MI) are usually (>90%) offered an early invasive strategy including coronary angiography possibly followed by intervention, preferably…
- Trial name
- NCT04488536
- Testing
- Clinical Frailty Scale
- Where
- 2 sites in Sweden
- Volunteers
- 10,000 people
- Sponsor
- Linkoeping University
Chronic Kidney Diseases
Evaluation of an Internet Based Education and Support Program for Patients Awaiting Kidney Transplantation
The goal of this study is to test the feasibility study of an internet based education and support program for patients awaiting kidney transplantation.
- Trial name
- INSERT (NCT06332469)
- Testing
- Internet based education and support program for patients awaiting kidney transplantation
- Where
- 2 sites in Sweden
- Volunteers
- 30 people
- Sponsor
- Linkoeping University
Idiopathic Scoliosis
Scoliosis-specific Exercises for Mild Idiopathic Scoliosis
Idiopathic scoliosis is the most common spinal deformity in children and adolescents with an estimated prevalence of 3%. About one tenth of the children with scoliosis develop a deformity that requires treatment with brace or…
- Trial name
- NCT05138393
- Testing
- Active self-corrective exercises, Observation
- Where
- 2 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Idiopathic Scoliosis
Trial on Three Treatments for Scoliosis
Idiopathic scoliosis is a three-dimensional structural deformity of the spine that occurs in children. Recent reviews on bracing and exercise treatment have provided some evidence for effect of these interventions.
- Trial name
- CONTRAIS (NCT01761305)
- Testing
- Hypercorrective night-time brace, Scoliosis specific exercises., Self-mediated physical activity.
- Where
- 7 sites in Sweden
- Volunteers
- 135 people
- Sponsor
- Karolinska Institutet
Postpartum
Effectiveness of a Smartphone App (PRIMI) to Promote Healthy Diet and Physical Activity After Pregnancy in Migrant Women
The PRIMI trial (Promoting Reproductive health In MIgrant women) is a randomized controlled trial evaluating the effectiveness of a smartphone app designed to promote a healthy diet, physical activity, and health literacy among…
- Trial name
- NCT06881277
- Testing
- Mobile phone based intervention
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Linkoeping University
Non-cardiac Chest Pain, Cardiac Anxiety
iCBT for Cardiac Anxiety in Patients With NCCP
Non-cardiac chest pain (NCCP) is a common condition that significantly affects patients' mental well-being, overall quality of life, and healthcare use.
- Trial name
- IKSIT2 (NCT06136494)
- Testing
- Internet-delivered cognitive behavioural therapy, Attention control
- Where
- Sweden
- Volunteers
- 126 people
- Sponsor
- Linkoeping University
Idiopathic Scoliosis
Brace Treatment for Idiopathic Scoliosis; PReventing Idiopathic SCOliosis PROgression
Idiopathic scoliosis is the most common spinal deformity in children and adolescents with an estimated prevalence of 3%. About one tenth of the children with scoliosis develop a deformity that requires treatment with brace or…
- Trial name
- PRISCOPRO (NCT04805437)
- Testing
- 3D TLSO, Standard TLSO
- Where
- 2 sites in Sweden
- Volunteers
- 170 people
- Sponsor
- Karolinska Institutet
Bladder Cancer
Information Needs and Supportive Rehabilitation Over Time in Patients Undergoing Cystectomy in Bladder Cancer
Bladder cancer is one of the diseases that can affect the urinary tract. Globally, it is the tenth most common cancer, with an incidence rate of 9.5 per 100,000 persons per year for men and 2.4 for women.
- Trial name
- CaRe (NCT07180121)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Linkoeping University