Clinical trials: sponsored by Minia University
Postoperative Pain
Clinical Efficacy of a Natural Biopolymer-Based Irrigant
One primary objective in the root canal treatments is to ensure chemo mechanical removal of microorganisms and organic/inorganic tissue residues from the infected root canals.
- Trial name
- NCT07901127
- Testing
- Chitosan Nanoparticles
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Minia University
Post Operative Cognitive Dysfunction
Pre-operative Intra-nasal Dexmedetomidine or Insulin for Prevention of Early Post-operative Cognitive Dysfunction in Patients Undergoing Elective Coronary Artery Bypass Graft.
On pump coronary revascularization is a very common leading cause for post-operative cognitive dysfunction regarding patient age grouping and diffuse systemic inflammatory response induced by bypass machine .
- Trial name
- NCT06741566
- Testing
- intranasal saline group, intranasal insulin, Intranasal dexmedetomidine
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
Deep Sclerectomy With Trabeculotomy in Advanced Glaucoma
Short-Term Efficacy and Safety of Combined Deep Sclerectomy With Trabeculotomy in Advanced Glaucoma: A Prospective Interventional Study
Brief Summary Glaucoma is a progressive eye disease that can lead to irreversible vision loss if intraocular pressure (IOP) is not adequately controlled.
- Trial name
- NCT07895537
- Testing
- Combined Deep Sclerectomy with Trabeculotomy
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Minia University
Chronic Apical Periodontitis
Effect of Cyperus Articulatus on Bacterial Reduction and Postoperative Pain
Successful endodontic treatment depends on effective elimination of microorganisms from the infected root canal system and prevention of reinfection.
- Trial name
- NCT07892690
- Testing
- Cyperus articulatus
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Periapical Healing
Evaluation of Three Different Intra-canal Medicaments
Periapical lesions are the commonly occurring pathologic lesions that affect the periradicular tissues of the tooth . This lesion can be classified as granuloma, cystic, or abscess .The pathologic changes seen in some…
- Trial name
- NCT07892703
- Testing
- Metapaste Calcium Hydroxide
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Minia University
Difficult Airway Management
Prediction of Difficult Mask Ventilation in Obese Population Undergoing Emergency Surgery
The current study is an observational, prospective study. It will be conducted in the emergency operative theatre, Alfayoum University, Alfayoum, Egypt.
- Trial name
- NCT07887503
- Volunteers
- 550 people
- Sponsor
- Minia University
Ventilator-associated Pneumonia, Traumatic Brain Injury
Closed Versus Open Endotracheal Suctioning and Ventilator-Associated Pneumonia in Severe Traumatic Brain Injury
This randomized controlled trial will compare closed versus open endotracheal suctioning techniques for preventing ventilator-associated pneumonia (VAP) in adults with severe traumatic brain injury (TBI) who need mechanical…
- Trial name
- NCT07883083
- Testing
- Closed endotracheal suction system, Open endotracheal suction
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Minia University
Obesity, Morbid
Sleeve Gastrectomy With Jejuno-ileal Bypass Versus Single Anastomosis Sleeve Jejunal Bypass
sleeve gastrectomy with jejunoileal bypass (SGJIB) is a novel technique for the surgical treatment of obesity. The aim of the study is to compare this maneuver with single anastomosis sleeve jejunal bypass (SAS-JB)
- Trial name
- NCT06530212
- Testing
- SGJIB, SAS-JB
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Minia University
Postoperative Analgesia in Patients Undergoing Open Renal Surgery
Ultrasound-Guided Midpoint Transverse Process to Pleura Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Patients Undergoing Open Renal Surgery :A Randomized Comparative Study.
The goal of this randomized comparative clinical trial is to compare the analgesic effectiveness of ultrasound-guided Midpoint Transverse Process to Pleura (MTP) block versus Erector Spinae Plane (ESP) block in adult patients…
- Trial name
- NCT07881523
- Testing
- Midpoint Transverse Process to Pleura (MTP)Block, Erector spinae plane (ESP) block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Minia University
Obesity, Morbid
Naturally Banded Versus Synthetic Banding of Sleeve Gastrectomy
to compare banding sleeve gastrectomy using silicone ring Versus using natural flap ( round ligament of the liver)
- Trial name
- NCT06298942
- Testing
- natural band, silicone band
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Minia University
Postoperative Pain, Middle Ear Surgery
Dexmedetomidine as an Adjuvant to Greater Auricular Nerve Block in Middle Ear Surgeries
This randomized, double-blind, controlled study will evaluate whether adding dexmedetomidine to bupivacaine in an ultrasound-guided greater auricular nerve block prolongs pain relief after middle ear surgery.
- Trial name
- NCT07878533
- Testing
- Bupivacaine, Dexmedetomidine, Normal saline
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Surgery, Neoadjuvant Chemotherapy
Comparative Study Between Immediate Surgery Versus Neoadjuvant Chemotherapy for Management of Resectable Pancreatic Cancer
This trial aimed to determine whether neoadjuvant chemoradiotherapy improves overall survival compared with upfront surgery, both followed by adjuvant chemotherapy in patients with resectable and borderline resectable pancreatic…
- Conditions
- Surgery, Neoadjuvant Chemotherapy, Management, Resectable Pancreatic Cancer
- Trial name
- NCT06978322
- Testing
- Immediate surgery, Neoadjuvant chemotherapy
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Minia University
Obesity, Morbid
Laparoscopic Natural Gastric Banding for Morbid Obesity
to do gastric banding using round ligament or omental flap instead of synesthetic band
- Trial name
- NCT05912920
- Testing
- gastric band
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Tooth Discoloration, Tooth Staining
Peroxide Versus Non-Peroxide In-Office Tooth Bleaching
This randomized clinical trial aims to compare the effectiveness of peroxide and non-peroxide in-office tooth bleaching systems.
- Trial name
- BECTS (NCT07818031)
- Testing
- peroxide -based in office tooth bleaching, non-peroxide -based in office tooth bleaching
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Minia University
Calcular Obstructive Jaundice, Gall Bladder Disease
One Session Vs Staged Management of Calcular Obstructive Jaundice
to compare the outcomes between doing ERCP and laparoscopic cholecystectomy in one session Vs staged management
- Trial name
- NCT05979233
- Testing
- staged managment, one session ERCP then LC, one session LC then ERCP
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Minia University
Vitiligo
Tyrosine Vs Tacrolimus With NB-UVB in Vitiligo
The goal of this clinical trial is to learn if adding topical tacrolimus or topical tyrosine to narrowband UVB phototherapy works to treat vitiligo in adults. It will also learn about the safety of both combinations.
- Trial name
- NCT07532330
- Testing
- Narrowband UVB Phototherapy, Topical Tacrolimus 0.1% ointment, Topical Tyrosine 2% cream
- Where
- Egypt
- Volunteers
- 67 people
- Sponsor
- Minia University
Post Operative Pain, Thoracic Surgery
Comparative Study Between Erector Spinae Plane Block Versus Combined Pectoralis and Serratus Interfascial Plane Blocks for Post-operative Analgesia After Thoracic Surgery.
The aim of this study is to evaluate the effect of combined pectoralis II and serratus interfascial plane blocks in comparison with erector spinae plane block on post-operative analgesia after thoracic surgeries.
- Trial name
- NCT07855549
- Testing
- Erector spinae plane block, Combined pectoralis and serratus anterior plane blocks
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Minia University
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Muscle Weakness
Growth Differentiation Factor 15 in ICU Acquired Muscle Weakness
Intensive care unit -acquired weakness (ICU- AW) is a common consequence linked to a worse outcome as evidenced by prolonged mechanical ventilation, longer ICU stays, greater mortality rates and a lower quality of life for…
- Trial name
- NCT06713746
- Testing
- growth differentiation factor 15
- Where
- Egypt
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Minia University
Pancreatic Cancer, Periampullary Cancer
Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas
This is a single-center, randomized controlled trial comparing the efficacy of pancreaticojejunostomy with modified N-butyl-2-cyanoacrylate(Glubran® 2) versus standard pancreaticojejunostomy without cyanoacrylate in preventing…
- Conditions
- Pancreatic Cancer, Periampullary Cancer, Duodenal Cancer, Cholangiocarcinoma
- Trial name
- NBCA-MS (NCT07155525)
- Testing
- Pancreaticojejunostomy with Modified N-Butyl-2-Cyanoacrylate (Glubran® 2), Standard(duct-to-mucosa) Pancreaticojejunostomy
- Where
- Egypt
- Volunteers
- 194 people
- Sponsor
- Minia University