Clinical trials: sponsored by Northwestern University
Whiplash Associated Disorders (WAD), Whiplash
Neuromuscular Mechanisms Underlying Poor Recovery From Whiplash Injuries
This study is investigating whether changes in the shape and size of bodily muscles and spinal cord anatomy can influence recovery rates following a motor vehicle collision (MVC).
- Trial name
- NCT02157038
- Testing
- Pedometer, MRI
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Northwestern University
Cutaneous T Cell Lymphoma
Characterization of the Microbiome in Cutaneous T Cell Lymphoma
Investigators plan to perform a pilot study that aims to characterize the microbiome of human cutaneous T cell lymphoma patients and compare this to the microbiome of age and sex matched controls.
- Trial name
- NCT03932279
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pain, Chronic
VR and Cooled Genicular Nerve Radio Frequency Ablation for Chronic Knee Pain
This study will examine the impact of virtual reality used in conjunction with sedation compared to sedation alone in patients undergoing watervcooled genicular nerve ablations for chronic knee pain.
- Trial name
- NCT06336447
- Testing
- Experimental: Group #1: Virtual Reality Headset, Group 2 No Virtual Reality Headset
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Northwestern University
Anxiety
Impact of Virtual Reality on Anxiety in Patients Undergoing Interventional Procedures
Periprocedural anxiety is a common problem for patients who undergo interventional pain procedures. Virtual Reality (VR) is an immersive experience that has gained acceptance in the medical field as a tool for reducing anxiety…
- Trial name
- NCT05744336
- Testing
- Group 1 Immersive Virtual Reality (VR), Group 2 Control Group
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Northwestern University
Breast Cancer, Arthralgia
Web-based Pain Coping Skills Training for Breast Cancer Survivors With AI-Associated Arthralgia
The main goal of this clinical trial is to test benefits of completing online pain coping skills training program in women who have been diagnosed with stage I-III breast cancer, who have completed their primary cancer treatment…
- Conditions
- Breast Cancer, Arthralgia, Pain, Chronic
- Trial name
- NCT05703178
- Testing
- Online Pain Coping Skills Training, Education
- Where
- 2 sites in United States
- Volunteers
- 452 people
- Sponsor
- Northwestern University
Nonsuicidal Self Injury, Suicidal Ideation
Digital Mental Health Intervention for Nonsuicidal Self-Injury in Young Adults
This is a feasibility trial of a digital mental health intervention aimed at young adults (ages 18-25) with nonsuicidal self-injury and who are not currently engaged in mental health treatment.
- Conditions
- Nonsuicidal Self Injury, Suicidal Ideation, Depression, Anxiety
- Trial name
- NCT05325944
- Testing
- Self-guided digital intervention for NSSI, Digital intervention for NSSI with coaching, Active control
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Northwestern University
Sudden Sensorineural Hearing Loss
Oral Statins and Protection From Hearing Loss
A small clinical trial for idiopathic sudden sensorineural hearing loss (ISSNHL). Will the addition of an oral statin to the standard treatment (oral methylprednesolone and the salvage therapy of intratympanic dexamethasone)…
- Trial name
- NCT04826237
- Testing
- Statin, methylprednisolone, dexamethasone
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Northwestern University
Melanoma (Skin Cancer)
Sun Exposure and Activities After Skin Cancer: Optimization of mHealth Interventions
The purpose of this study is to evaluate 5 different smartphone administered sun protection interventions that aim to reduce unprotected sun exposure in melanoma survivors.
- Trial name
- SESAME (NCT07556380)
- Testing
- UV Real-Time Alerts, Track Your Sun Protection, Current Conditions
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Northwestern University
Borderline Resectable Pancreatic Ductal Adenocarcinoma, Resectable Pancreatic Ductal Adenocarcinoma
SMAD4 Tailored Neoadjuvant Therapy for the Treatment of Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma, SMART-PANC Trial
This phase II trial tests the impact of using SMAD4-mutant status to personalize chemotherapy in treating patients with pancreatic ductal adenocarcinoma (PDAC) that can be removed by surgery (resectable) or that may be between…
- Trial name
- NCT07748611
- Testing
- Biospecimen Collection, Computed Tomography, Electronic Health Record Review
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Northwestern University
Liver Transplant Rejection
Erythropoietin Therapy to Induce Regulatory T Cells in Liver Transplant Recipients
The goal of this proof-of-concept study is to EPO increases the frequency, stability and/or function of Tregs in liver transplant recipients.
- Trial name
- NCT05325073
- Testing
- Erythropoietin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Northwestern University
Colorectal Cancer
The PRIME-CRC Trial to Promote CRC Screening in Rural Communities
The investigators will expand an existing, patient-centered, health literacy strategy to promote longer-term adherence to colorectal cancer (CRC) screening in resource-limited, rural health clinics via colonoscopy or annual fecal…
- Trial name
- NCT04313114
- Testing
- health literacy appropriate education and demonstration, shared decision making, automated call reminders or automated texts
- Where
- 3 sites in United States
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Healthy Adult, Flushing
ALDH2 Genetic Testing in East Asian Community
The goal of this clinical trial is to learn whether education plus genetic testing for ALDH2*2 and ADH1B*2 is feasible and acceptable and whether it influences modifiable health behaviors in East Asian American adults who…
- Trial name
- NCT07392775
- Testing
- Genetic Test Results Return, Alcohol Flushing Education
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Alzheimer's Disease (AD), Dementia
Negotiation Training for Family Caregivers of People With Alzheimer's Disease
Family caregivers of people living with Alzheimer's disease and related dementias often experience conflicts and communication challenges when coordinating care, making decisions, and interacting with family members and…
- Conditions
- Alzheimer's Disease (AD), Dementia, Cognitive Impairment
- Trial name
- NCT07859540
- Testing
- NegotiAge, PlanYourLifespan
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northwestern University
HIV/AIDS, Gonorrhea
A Pragmatic Trial of Two Strategies for Implementing an Effective eHealth HIV Prevention Program (Keep It Up! 3.0)
This study evaluates and compares two implementation strategies of an online HIV prevention intervention: Strategy 1 in which community-based organizations apply, and are selected, for funding to deliver Keep It Up! through…
- Conditions
- HIV/AIDS, Gonorrhea, Chlamydia
- Trial name
- NCT03896776
- Testing
- Keep It Up! 3.0
- Where
- United States
- Volunteers
- 2,249 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Trauma, Appendectomy
Hospital Based Continuous Patient Monitoring System
In Ghana, and many other low and middle income countries in Africa, manual vital signs monitoring is the prevalent mode of vital signs monitoring because continuous bedside monitors are non-functional.
- Conditions
- Trauma, Appendectomy, Pediatric ALL, Vital Signs Monitoring
- Trial name
- NCT06739447
- Testing
- Consumer Wearable Device Vital Sign Measurement
- Where
- Ghana
- Volunteers
- 250 people
- Sponsor
- University of Alabama at Birmingham
Hypertensive Disorders of Pregnancy, Preeclampsia
Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
The overall goal of this large, pragmatic, comparative effectiveness trial is to test the hypothesis that among at-risk individuals, 162 mg/day aspirin is superior to 81 mg/day in preventing Hypertensive disorders of pregnancy…
- Conditions
- Hypertensive Disorders of Pregnancy, Preeclampsia, Gestational Hypertension
- Trial name
- ASPIRIN (NCT06468202)
- Testing
- Aspirin 81 mg, Aspirin 162 mg
- Where
- 20 sites in United States
- Volunteers
- 10,742 people
- Sponsor
- Ohio State University
Lung Carcinoma, Lung Non-Small Cell Carcinoma
Using an Artificial Intelligence Software Tool (iSeg) During Radiation Treatment Planning for Patients With Lung Tumors
This clinical trial studies whether an artificial intelligence (AI) software tool called iSeg can be safely and effectively used during routine radiation treatment planning for patients with lung tumors.
- Conditions
- Lung Carcinoma, Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Lung
- Trial name
- NCT07898241
- Testing
- Artificial Intelligence-based Intervention, Best Practice, Computed Tomography
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Northwestern University
Glioblastoma, Gliosarcoma
Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma
Paclitaxel is among the most active agents against glioblastoma in preclinical models. However, its clinical use has been hampered by the blood-brain barrier (BBB).
- Conditions
- Glioblastoma, Gliosarcoma, GBM, Glioblastoma Multiforme
- Trial name
- SC9/ABX (NCT04528680)
- Testing
- Sonication for opening of blood-brain barrier, Chemotherapy, albumin-bound paclitaxel, Chemotherapy, carboplatin
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Northwestern University
Chronic Low Back Pain
The Ability of Chronic Pain Patients to Self-diagnose Their Chief Source of Low Back Pain
The investigative team will provide 27 (28 with title) slides with bullet points and images of pain referral patterns for different causes (e.g., herniated disc, facet joint arthritis) for patients seen for a new visit with a…
- Trial name
- NCT06630676
- Testing
- Control, Education
- Where
- 2 sites in United States
- Volunteers
- 288 people
- Sponsor
- Northwestern University
Ulcerative Colitis
Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)
Chronic intestinal hypoxia and accompanying mucosal inflammation is a hallmark of ulcerative colitis (UC). Hyperbaric oxygen therapy (HBOT) involves breathing 100% oxygen under increased atmospheric pressure to increase tissue…
- Trial name
- HBOT-UC (NCT05987852)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- 13 sites in United States
- Volunteers
- 126 people
- Sponsor
- Northwestern University
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