Clinical trials: sponsored by Poitiers University Hospital
End Stage Renal Disease (ESRD)
Effect of Medium Cut-Off Hemodialysis on Protein Energy Wasting: The EMCOPEW Study
In patients on maintenance hemodialysis (HD), protein energy wasting (PEW) defined as loss of muscle mass and fuel reserves of the body is frequent and associated with severe morbidity and mortality.
- Trial name
- EMCOPEW (NCT05309109)
- Testing
- Hemodialysis sessions
- Where
- 2 sites in France
- Volunteers
- 65 people
- Sponsor
- Poitiers University Hospital
Intermittent Hypoxia, Healthy Volunteers
Influence of Intermittent Hypoxia on Loop Gain in Healthy Subjects
Sleep apnoea-hypopnoea syndrome (SAHOS), which causes numerous comorbidities, particularly cardiovascular ones, is widespread worldwide today and incurs significant healthcare costs.
- Trial name
- HI-LOOP (NCT07409649)
- Testing
- Intermittent hypoxia, Normoxia
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Neuropsychological Tests, Memory
Adaptation and Normalization of a Verbal Episodic Memory Test in French Sign Language
To date, neuropsychological assessment of deaf signing persons is complicated by a lack of resources, especially the absence of tools available in French Sign Language (LSF).
- Conditions
- Neuropsychological Tests, Memory, Alzheimer Disease, Deafness
- Trial name
- RL-RI-LSF (NCT06902753)
- Testing
- Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Mycobacterium; Xenopi, Lung Diseases
Amikacin Liposome Inhalation Suspension for Treatment of Mycobacterium Xenopi Pulmonary Infection
Treatment of Mycobacterium xenopi (MX) lung disease is not-well- tolerated and concerned a growing number of patients, especially with chronic pulmonary diseases or immunosuppression.
- Trial name
- AKAPI (NCT06585020)
- Testing
- Arikayce, standard treatment
- Where
- France
- Volunteers
- 190 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Type 1 Diabetes, Coronary Artery Calcification
Cardiovascular Risk Stratification in Young People With Type 1 Diabetes
The aim of the study is to compare ESC recommendations on cardiovascular (CV) risk stratification with the achievement of a CAC (Coronary Artery Calcification).
- Trial name
- CACD1 (NCT05283538)
- Testing
- Coronary Artery Calcification Realization
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Poitiers University Hospital
Medical Imaging
Defining Dosimetric Reference Levels in Computed Tomography Spectral Scanning
Spectral computed tomography or dual-energy CT imaging can overcome the limitations of conventional CT in differentiating between two materials with equivalent total attenuation.
- Trial name
- NR Spectral (NCT07305103)
- Testing
- Spectral ComputedTomography
- Where
- France
- Volunteers
- 9,600 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Permanent Atrial Fibrillation, Preserved Ejection Fraction
Bundle Branch Pacing to Preserve Ejection Fraction in Atrial Fibrillation Trial
The goal of this clinical trial is to learn whether left bundle branch area pacing, a technique designed to activate the heart's natural electrical conduction system, is better than conventional right ventricular pacing in adults…
- Trial name
- BEAT (NCT07759700)
- Testing
- LBBA pacing, Conventional pacing
- Where
- France
- Volunteers
- 642 people
- Sponsor
- Poitiers University Hospital
Heart Failure
HeartLogic™ in Patients With Heart Failure.
This randomized, multicenter clinical trial will evaluate whether remote management guided by the HeartLogic™ algorithm improves outcomes compared with traditional face-to-face follow-up in adult patients with heart failure…
- Trial name
- HERO (NCT07544771)
- Testing
- Alert-guided remote follow-up, Traditional follow up
- Where
- 15 sites in France
- Volunteers
- 578 people
- Sponsor
- Poitiers University Hospital
Myocardial Infarction
CARdiAc Mri and BiOLogical samplEs at the Acute Phase of a Myocardial Infarction (CARAMBOLE)
ST-Segment Elevation Myocardial infarction (STEMI) corresponding to acute occlusion of cornary artery is the most severe ischemic myocardial disease and a leading cause of mortality of heart failure worldwide.
- Trial name
- CARAMBOLE (NCT06278519)
- Testing
- Blood, urinary and feces collection, Cardiac MRI, Quality of life and cognitive status questionnaire
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Poitiers University Hospital
Dyspnea
The Impact of Telemedicine, Using the Caller's Mobile Phone Camera, on the Quality of Care Provided to Adult Patients Contacting the 15 Centre for Acute Dyspnea
Dyspnea is the subjective sensation of difficult or uncomfortable breathing. It accounts for approximately 10% of emergency department visits and 8% of calls to Emergency Medical Communication Centers.
- Trial name
- TELEDYS (NCT07726628)
- Testing
- Addition of telemedine to standard medical dispatching process
- Where
- 10 sites in France
- Volunteers
- 778 people
- Sponsor
- Poitiers University Hospital
Alzheimer Disease, Magnetic Resonance Spectroscopy
New Imaging Biomarkers Predictive of MA Progression
The pathophysiology of AD is complex. In addition to amyloid plaques and neurofibrillary degeneration, there is a metabolic alteration of the energy pathways, oxidative phosphorylation and glycolysis, which are involved in brain…
- Conditions
- Alzheimer Disease, Magnetic Resonance Spectroscopy, Ultra High Field 7T, Progression of Disease
- Trial name
- MR7T-PRADA (NCT05939362)
- Testing
- MRI follow-up
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Poitiers University Hospital
Middle Cerebral Artery Acute Ischemic Stroke
Predictive Multimodal MRI Factors in Subacute Cerebral Artery Occlusiontreated by Thrombectomy (PIMISUTT)
Our study aims to measure metabolic and functional parameters of the infarcted territory by multimodal cerebral MRI in patients diagnosed with unilateral proximal occlusion of the middle cerebral artery and treated by…
- Trial name
- PIMISUTT (NCT04651010)
- Testing
- Multimodal MRI
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Poitiers University Hospital
Pneumocystis Pneumonia, Pneumocystis Jirovecii Infection
CaspoNEB: Efficacy and Safety of Caspofungin Aerosols for the Curative Treatment of Pneumocystis Pneumonia
To assess the efficacy of administrating daily caspofungin aerosols versus placebo for seven days, in adjunction of conventional systemic antifungal therapy during curative treatment of Pneumocystis pneumonia, on the clinical…
- Conditions
- Pneumocystis Pneumonia, Pneumocystis Jirovecii Infection, Pneumocystis Infections
- Trial name
- CaspoNEB (NCT06892951)
- Testing
- Caspofungin Acetate 50 MG, Physiologic saline
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Hypothermia; Anesthesia, Perioperative/Postoperative Complications
Impact of a Global Warming Strategy of the Patient on the Prevalence of Hypothermia in the Recovering Room
50% of patients are hypothermic when they arrive in the recovery room. This hypothermia is potentially at risk for the patient (increases bleeding, risk of infection, risk of cardiac involvement, morbid mortality) and 33,2% steel…
- Trial name
- REGLO (NCT06551558)
- Testing
- global warming, per operative warming
- Where
- France
- Volunteers
- 174 people
- Sponsor
- Poitiers University Hospital
Intensive Care Unit (ICU), Sleep Disruption
Impact on Prognosis of Increased Sleep Quality Obtained by Personalized Night-time Nursing Care in Critically Ill Patients
Sleep disturbances are common among intensive care unit (ICU) patients and have been associated with difficult weaning from invasive mechanical ventilation, with an increased risk of endotracheal intubation.
- Conditions
- Intensive Care Unit (ICU), Sleep Disruption, Sleep Monitoring
- Trial name
- MEDICOSLEEP (NCT07606495)
- Testing
- Sleepscan device, Sleep-guided nursing care
- Where
- 7 sites in France
- Volunteers
- 460 people
- Sponsor
- Poitiers University Hospital
Alzheimer Disease (AD)
Assessment of Changes in Autonomy Through Analysis of Smartphone Usage Data in Patients With Alzheimer's Disease
Alzheimer's disease is the leading cause of dementia worldwide. The first cognitive function to be affected is memory. As the disease progresses, other cognitive systems are affected, leading to a gradual loss of independence for…
- Trial name
- AUMASMART (NCT07826975)
- Testing
- Data collection, Neuropsychological assesment, Autonomy questionnaire
- Volunteers
- 100 people
- Sponsor
- Poitiers University Hospital
Bladder Cancer, Transurethral Resection of the Bladder
Relevance of the Urine Bacterial Culture Performed Before TransUrethral Resection of the Bladder for Post-operative Febrile Urinary Tract Infections Prevention: a Non-inferiority Randomized Controlled Trial
The main objective of the study is to demonstrate that not performing a systematic UC before the TURB procedure is non-inferior to performing a systematic UC in terms of the incidence of febrile UTIs during the first 30…
- Conditions
- Bladder Cancer, Transurethral Resection of the Bladder, Urinary Tract Infection Bacterial
- Trial name
- RUPTURE (NCT07463963)
- Testing
- Urine bacterial Culture (UC), No intervention before TURB surgery
- Where
- 15 sites in France
- Volunteers
- 2,600 people
- Sponsor
- Poitiers University Hospital
Non Muscle-invasive Bladder Cancer
Evaluation of Immediate Preoperative Instillation (IPOI) of Mitomycin C Compared to Early Postoperative Instillation (IPOP) in Non-muscle Invasive Bladder Cancer
This study seeks to optimize the management of TVNIM (reduction of the risk of reccurence of the disease) by comparing in terms of efficacy and tolerance the immediate preoperative administration of mitomycin C (IPOI) to an early…
- Trial name
- NCT02075060
- Testing
- IPOI, IPOP
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- Poitiers University Hospital
Out-of-hospital Setting, Dyspnea
Videoconferencing for the Management of Paediatric Dyspnoea in an Emergency Medical Call Centre
Dyspnoea is defined as the sensation of difficult or uncomfortable breathing experienced by a patient. It is a significant concern in emergency care, accounting for 8% of calls to the emergency medical call centre (EMCC) and 10%…
- Trial name
- VISIODYS-PED (NCT06847997)
- Testing
- Addition of telemedicine to standard medical dispatching process (Experimental Group)
- Where
- France
- Volunteers
- 339 people
- Sponsor
- Poitiers University Hospital
Peripheral Venous Catheterization
Comparison of the Effectiveness of Ultrasound-guided Techniques and Infrared Illumination, Compared With the Standard Approach to Peripheral Venous Line Placement in People With Difficult Venous Access
Peripheral venous catheterization (PVC) is the most common invasive procedure in healthcare worldwide. Improving the success rate of PVC on the first attempt is crucial for patients, as it impacts pain, anxiety, the risk of…
- Trial name
- REUSSIR-VVP (NCT06838364)
- Testing
- Infrared peripheral venous technique, Ultrasound-guided peripheral venous technique, Landmark technique
- Where
- France
- Volunteers
- 264 people
- Sponsor
- Poitiers University Hospital